• Journal of Microbiology and Biotechnology
• /
• v.3 no.1
• /
• pp.57-60
• /
• 1993

The herbicidal compound, 3D5 was isolated from the culture broth of strain 3D5, a soil isolate. Based on taxonomic studies, this culture was identified as Streptomyces sp. 3D5.

• Journal of Microbiology and Biotechnology
• /
• v.3 no.1
• /
• pp.51-56
• /
• 1993

The structure of herbicidal compound, 3D5, isolated from the culture broth of Streptomyces sp. 3D5, was elucidated as a 16-membered diene macrolide by the spectroscopic method. It was identical with bafilomycin D which has been known to be an insecticidal compound and an inhibitor of $K^{+}-dependent$ ATPase. However, this is the first report which shows that bafilomycin D has a herbicidal activity.

• Korean Journal of Weed Science
• /
• v.30 no.4
• /
• pp.437-444
• /
• 2010

This study was conducted to determine the herbicidal activity of allelochemicals and identify herbicidal compounds in bulbs of Lycoris chinensis var. sinuolata. Methanol extract was purified by a series of silica gel flash column chromatography and HPLC. The final HPLC gave two active fractions and an herbicidal compound was obtained. By GC/MS analysis, the herbicidal compound was identified as montanine ($O^2$-methyl pancracine), an isoquinoline alkaloid. Montanine showed 100% of growth inhibition on the shoot and root of barnyardgrass (Echinochloa crus-galli) seedlings at $50\;{\mu}g\;mL^{-1}$ as compared with the control.

• Microbiology and Biotechnology Letters
• /
• v.24 no.1
• /
• pp.82-86
• /
• 1996

Three thousand microbial strains collected from different sources were screened for herbicidal activity. A strain of ME-9189 showed herbicidal activity against Digitaria sanguinalis and Portulaca oleracea was isolated from a mountainy soil. Based on taxonomic studies, the strain was identified as Streptomyces tubercidicus. The active compound of ME-9189 was purified from the culture broth by charcoal, silica gel, sephadex LH-20 column chromatography and crystalization, consecutively. The ME-9189 compound was identified as tubercidin by spectroscopic methods of UV, $^{1}H$ and $^{13}C$-NMR, and EIMS. In the bioassay, growth of radish shoot and root was inhibited by 50% with tubercidin treatment of 10 ppm, showing 2 times higher activity than that of herbicidin A and similar to that of toyocamycin.

• The Korean Journal of Pesticide Science
• /
• v.3 no.3
• /
• pp.1-5
• /
• 1999

Novel O-quinolinylamidoxime derivatives were prepared by replacement of the carboxylic group at the 8 position of quinclorac with various amidoximes. In the flooded paddy conditions, most of the compounds show good herbicidal activity at a rate of 1 kg/ha. Some of them showed excellent herbicidal activity at a rate of 60 g/ha against barnyardgrass (Echinochloa aryicola) with good selectivity on rice. Under the two-leaf stage of barnyardgrass, most of O-quinolinylamidoximes showed good herbicidal activity, expecially compound 3c which showed excellent herbicidal activity barnyardgrass at a rate of 125 g/ha with good rice seletivity.

• Journal of the Korean Chemical Society
• /
• v.48 no.4
• /
• pp.385-393
• /
• 2004

2-Ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide (8) was synthesized from benzofuroxan and ethyl acetoacetate. The reaction of compound 8 with hydrazine hydrate or selenium dioxide gave 2-hydrazinocarbonyl-3-methylquinoxaline 1,4-dioxide (9) or 2-ethoxycarbonyl-3-formylquinoxaline 1,4-dioxide (10), respectively. The reaction of compound 9 with alkanoyl chlorides, benzoyl chlorides, heteroacyl chlorides, and benzenesulfonyl chlorides afforded 3-methyl-2-(substituted hydrazinocarbonyl)quinoxaline 1,4-dioxides (11-14), respectively. The reaction of compound 9 with sodium azide gave 2-azidocarbonyl-3-methylquinoxaline 1,4-dioxide (15), and then its refluxing in dioxane/alcohols resulted in the Curtius rearrangement to give N-(3-methyl-1,4-dioxoquinoxalin-2-yl)-alkyl carbamates (16). The reaction of compound 15 with substituted anilines afforded 2-(3-substituted phenylureido)-3-methylquinoxaline 1,4-dioxides (17). The reaction of compound 10 with benzoic hydrazide or substituted anilines provided quinoxaline 1,4-di-oxides (18, 19), respectively. The herbicidal and fungicidal activities of the synthesized compounds were investigated.

• The Korean Journal of Pesticide Science
• /
• v.5 no.4
• /
• pp.68-71
• /
• 2001

Of the cyclic imide type compounds, S-275 was known to exhibit a potent herbicidal effects. We have designed and synthesized the compounds having diverse subsutuents in place of the chlorine group of bicyclic 4,5,6,7-tetrahydroindazole part of S-275. Their herbicidal activities were studied under flooded paddy conditions. The results showed that the most compounds gave relatively weak herbicidal activities, whereas tile compound substituted with methylthio group showed potent herbicidal effects against paddy weeds at a rate of 0.015 kg/ha and improved tolerance on rice compared to S-275.

• Korean Journal of Weed Science
• /
• v.31 no.1
• /
• pp.112-117
• /
• 2011

A series of experiments was conducted to investigate the herbicidal activity of natural compound chrysophanic acid under the greenhouse condition in 16 weed species. Chrysophanic acid showed non-selective herbicidal activity. While chrysophanic acid exhibited severe injury by foliar treatment, little or no injury was found by the soil treatment. Among the tested weeds, the most effective activity was found in grass and broad leaf weeds, a lower significant difference in herbicidal activity was found in sedge. At early post-emergence, weeds appeared to be very susceptible to chrysophanic acid with $2,000{\mu}g\;mL^{-1}$. The higher the natural compound concentrations, the lower weed growth. At middle post-emergence, weeds appeared to be very effective to chrysophanic acid with $30,000{\mu}g\;mL^{-1}$.

• The Korean Journal of Pesticide Science
• /
• v.10 no.2
• /
• pp.153-156
• /
• 2006

As an ongoing research program for the development of environmentally friendly new herbicide, several hydantoin derivatives 5a - 5i possessing amide subgroup were synthesized and shown to have interesting herbicidal activities exhibiting symptoms as Protoporphyrinogen IX oxidase inhibitor under postemergence upland greenhouse screening. Among derivatives tested, compound 5h showed superior herbicidal activity against upland problem weed, digitaria sanguinalis and aeschynomene indica to reference compound fluthiacet-methyl.

• Journal of the Korean Chemical Society
• /
• v.47 no.3
• /
• pp.241-249
• /
• 2003

The reaction of 3-(1-ethoxycarbonyl)ethyl-1,2-dihydro-2-oxoquinoxaline (8) with hydrazine hydrate gave 3-(1-hydrazinocarbonyl)ethyl-2-hydroxyquinoxaline (9). The reaction of compound 9 with substituted benzaldehydes and heteroaryl aldehydes afforded 2-hydroxyquinoxalines (10-12), respectively. The reaction of compound 9 with alkyl (ethoxymethylene)cyanoacetates and ethoxymethylenemalononitrile resulted in the intramolecular cyclization to give the 5-amino-1-[2-(3-hydroxyquinoxalin-2-yl)propanoyl]-pyrazoles (13), respectively. Compounds 10-13 showed the tautomerism between the lactam and lactim forms in dimethyl sulfoxide solution. The tautomer ratios were determined by the $^1H$ NMR. The herbicidal and fungicidal activities of the synthesized compounds were investigated.