• Title/Summary/Keyword: Herbal Materials

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Research of Traditional Herbal Medicines for Anti-inflammatory Effects - Focusing on in vitro experiments - (항염증 효능을 가진 한약물에 관한 고찰 - 시험관내 실험을 중심으로 -)

  • Lee, Soo-Jin
    • Journal of Haehwa Medicine
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    • v.22 no.1
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    • pp.37-48
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    • 2013
  • This study aims to summarize and makes a reference of anti-inflammatory activities of herbal medicines. In this process, this review collated papers of anti-inflammation-focused studies using herbal medicines in Oriental medical journals since 2003. Finally 221 papers were included and the type of materials, the type and effective classification of herbal medicines, the type of cells used in the experiments and the action and mechanisms of herbal medicine were analysed. The herbal medicines having the effects of decreasing fire and tonifying and nourishment were used the most. Most herbal medicines in this study can decrease proinflammatory cytokines, NO and prostaglandin 2 (PGE 2) production, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by regulating of nuclear factor kappa B (NF-${\kappa}B$) and/or mitogen activated protein kinases (MAPKs).

Studies on the development of functional paper with herbal medicine and herbal medicine waste(Part 1) -Development of functional paper with Astragalus membranaceus, Angelica acutiloba and Artemisia capillaris waste- (한약재 및 한약 폐잔재를 이용한 기능지 개발에 관한 연구(제 1보) - 황기, 당귀, 인진쑥의 폐잔재를 이용한 기능지 개발 -)

  • Kim, Kyoung-Shin;Yoon, Seung-Lak;Ro, Jeong-Kwan;Jo, Hyun-Jin;Kim, Byoung-Soo;Kim, Yun-Geun
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.45 no.3
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    • pp.9-19
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    • 2013
  • This research was performed to make functional papers by using the waste of herbal medicine such as Astragalus membranaceus, Angelica acutiloba, and Artemisia capillaris as additives, and to evaluate their physical and optical properties of the manufactured paper. The physical and optical properties were decreased with the increase of the amount of herbal medicine. Of those manufactured papers, the functional paper with Artemisia capillaris showed the dramatic decrease in its physical properties. Adding the herbal medicine waste as additives developed the aesthetic pattern on the surface of the manufactured paper. The paper showing the black pattern on white surface was most favored. Different patterns could be made by changing the size of fibers and the amount of wastes. There was odor emitted from the paper due to the herbal medicine waste, which make the paper to have a potential for the diverse purpose. The herbal medicine waste can be applied to replace weighting agents in the manufacturing process of paper or used for the fuctional additives, resulting in the reduce of the quantity of a pulp consumed. The paper with 10-20% Angelica acutiloba waste were thought to have the most excellent quality on the process point of view.

Toxicological Study on Korean Tea Materials: Screening of Potential Mutagenic Activities by Using SOS-Chromotest (한국차(韓國茶) 원료(原料)에 대한 독성(毒性) 연구(硏究) -변이원성(變異原性) 검색(檢索)-)

  • Pang, Hyung-Ae;Lee, Young-Wook;Suh, Nan-Joo;Chang, Il-Moo
    • Korean Journal of Pharmacognosy
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    • v.21 no.1
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    • pp.83-87
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    • 1990
  • In terms of regulatory toxicology, especially for the traditional Chinese medicines, problems can be arise from a fact that there is no distinctive barrier between herbal drugs and food/beverage. An example is that many kinds of Chinese herbal materials have been also used as tea materials in Korea, China, Japan and Vietnam. Sixteen tea materials (also used as herbal materials) were extracted with 70% ethanol and the extract further partitioned with chloroform and water. Those ethanol extract and fractions were subjected to the SOS-Chromotest to examine potential mutagenicity. It was found that ethanol extract of Chaenomelis Fructus (Chaenomeles japonica Lindley, 木瓜, Rosaceae) and both ethanol extract and water fraction of Cassiae Semen (Cassia tora Linne, 決明子, Leguminosae) showed relatively high mutagenic activities in SOS-Chromotest.

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Evidence-based herbal medicine in efficacy and safety assessments

  • Park, Jin-Han
    • Advances in Traditional Medicine
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    • v.8 no.2
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    • pp.103-110
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    • 2008
  • Herbal medicine is the use of medicinal plants for prevention and treatment of diseases: it ranges from traditional and popular medicines of every country to the use of standardized and tritated herbal extracts. Generally cultural rootedness enduring and widespread use in a traditional medical system may indicate safety, but also efficacy of treatments, especially in herbal medicine where tradition is almost completely based on remedies containing active principles at very low and ultra low concentrations or relying on magical-energetic principles. The efficacy and safety assessments of medicines, whether modern or herbal, invariably encounter challenges or problems during the course of pre-clinical and clinical research. Some of the challenges in evidence-based herbal medicinal research are unique, and the researcher must be cognizant of them in order to safeguard the quality of the data obtained. Key challenges are: the quality of raw materials; appropriateness of biological/pharmacological activity assessment methodology, and data interpretation; standardization methodology; pharmacokinetics and bioavailability of active constituents and metabolites; clinical dosage formulation/production; and clinical study designs and outcome measures.

Elemental Analysis of herbal medicine, Foundry Air and Hair for the Study of Human Surroundings (인체 환경 연구를 위한 한약재, 작업장 공기 및 모발의 원소분석)

  • 강상훈;이상순;조승연;정용삼
    • Journal of Environmental Health Sciences
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    • v.28 no.3
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    • pp.64-71
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    • 2002
  • Hair provides important information about the body's mineral status. Therefore, we have studied the trace elemental distribution in human hair under different inhalation and ingestion environment using neutron activation analysis (NAA). NAA is a powerful analytical method which can be used successfully to determine trace elements in environmental and biological materials. Total diet and six different herbal medicine were analysed to study ingestion environment. Airborne dust in foundry was analysed and compared with outdoor dust to study inhalation environment. Human hairs of common person, herbal medicine taker and foundry worker were analysed to estimate the trace elemental distribution of people under different inhalation and ingestion environment. Analytical results show that herbal medicines contain higher micronutrients such as Ca, Mg, Mn and Cu that total diet and airborne dust in foundry has high Cr. The concentration of Ca, Mg and Mn in hair of herbal medicine taker is two times higher than in hair of common person and Cr con-centration in hair of foundry worker is about three times higher than in hair of common person. These results show that NAA can be used importantly to monitor human health through biological and environmental samples.

The Changes of Benzo[α]pyrene in Herbal Teas containing Astragalus membranaceus, Schizandra chinensis, Liriope platyphylla and Platycodon grandiflorum Which are affected by the Puffing Conditions (Puffing 조건에 따른 황기, 오미자, 맥문동 및 길경을 첨가한 한방차의 Benzo[α]pyrene 변화)

  • Oh, Sung-Cheon
    • The Korean Journal of Food And Nutrition
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    • v.27 no.1
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    • pp.75-79
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    • 2014
  • The following study is the result of herbal teas puffed at different temperatures between $140{\sim}220^{\circ}C$. Depending on treatment temperatures, the water contents decreased, while some carbonization occurred and crude ash contents relatively increased. Also, the crude protein and crude fat experienced little changes. B(${\alpha}$)P contents (0.16~0.17 ppb) showed little change according to treatment temperatures. From this result, the B(${\alpha}$)P content differed depending on the treatment temperature and raw materials. Solid elution rate figures of the herbal teas ranged from 0.27~0.45% (w/w) and the rate of solid elution increased along with higher puffing temperatures. The reason for the increase in solid elution rates is due to the breakage of cross bridges between the raw materials in the herbal tea which are carbohydrates, proteins, lipids and etc. after treatments of physical changes rather than chemical ones.