• Korean Journal of Radiology
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• 제22권7호
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• pp.1110-1123
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• 2021

Owing to improvements in surgical techniques and medical care, living-donor liver transplantation has become an established treatment modality in patients with end-stage liver disease. However, various vascular or non-vascular complications may occur during or after transplantation. Herein, we review how interventional radiologic techniques can be used to treat these complications.

• Archives of Plastic Surgery
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• 제33권4호
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• pp.454-457
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• 2006

Purpose: The anastomosis of hepatic artery to recipient vessel has a major role in a liver transplantation, so its occlusion is the most important cause of failure of liver transplantations. We made the study to reveal the peculiarities in pediatric liver transplantations compared with adult cases. Methods: From January 1999 to September 2005, we performed 99 cases of pediatric liver transplantation. The mean age at operation was 4.17 years of age. The hepatic vein and portal vein are anastomosed by the general surgeons and then the hepatic artery is anastomosed by the plastic surgeons. The Doppler ultrasonography and computed tomography were used for postoperative checkup for hepatic artery patency. Results: There were no immediate complications, but hepatic arterial occlusion was developed in 3 cases (2.8%). In pediatric patients, the anastomosis of hepatic artery is more difficult than adults because of the rapid respiratory and pulse rate, the small vascular diameter, and the large gap of diameter difference between the recipient and the donor vessels. Conclusion: We could confirm that pediatric liver transplantations are relatively safe but long learning curve was needed.

• 대한영상의학회지
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• 제84권3호
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• pp.586-595
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• 2023

제대 정맥 카테터는 미숙아 혹은 위중한 만삭아에게 중심 정맥을 통한 총 비경구 영양 및 약물을 제공하기 위해 흔하게 사용된다. 하지만 제대 정맥 사용은 감염, 문맥 혈전증 및 간 조직 손상을 포함하는 합병증을 유발할 수 있다. 잘못 거치된 제대 정맥 카테터를 통하여 부주의하게 고장성 액체를 투여 시 액체 저류를 동반한 간실질 손상을 유발할 수 있으며, 영상검사에서 이러한 액체 저류는 종양성 병변으로 오인될 수 있다. 초음파와 엑스선 검사는 이러한 제대 정맥 카테터 관련 합병증을 감지하는 데 필수적인 역할을 한다. 이 논문에서는 신생아의 제대 정맥 카테터 관련 간 합병증의 영상 소견에 대해 기술할 것이다.

• Journal of Nutrition and Health
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• 제40권4호
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• pp.295-302
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• 2007

This study was designed to examine the effects of fractions of ethanol extract of Benincasa hispida (wax gourd) on hepatic antioxidative status in streptozotocin (STZ) induced diabetic rats. Sprague-Dawley rats were induced diabetes mellitus by STZ injection (45 mg/kg) into the tail vein and were divided into 5 groups: normal, STZ-control, three experimental diabetic groups. Fractions of ethanol extract of Benincasa hispida were administered orally into the diabetic rats for 14 days. Hepatic glutathione peroxidase (GSH-px) activity (determined with H$_2$O$_2$ as substrate) was increased in the groups supplemented with chloroform (CHCl$_3$) and butanol (BuOH) fractions. Glutathione peroxidase (GR) activity in the liver cytosol of H$_2$O fraction groups was significantly lower than that of STZ-control group. The H$_{2}$O fraction supplemented group has been shown the notably decrease in the hepatic superoxide dismutase (SOD) activity. The hepatic cytosol catalase (CAT) activity was significant decreased by the supplementation with BuOH fraction. It was found from the results that the supplementation of BuOH and H$_2$O fractions of Benincasa hispida extract could be beneficial for the diabetic complications and damages from the lipid peroxidation.

• Journal of Yeungnam Medical Science
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• 제32권1호
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• pp.38-41
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• 2015

Pyogenic liver abscess with metastatic septic complications is a rare and serious infectious disease if not treated properly. Pyogenic liver abscesses are caused by bacterial, fungal, or parasitic organisms. Escherichia coli used to be the predominant causative agent, but Klebsiella pneumoniae emerged as a major cause in the 1990s. Liver abscesses are caused by hepatic invasion via many routes, such as, the biliary tree, portal vein, hepatic artery, direct extension, or penetrating trauma. Furthermore, diabetes mellitus and malignant conditions are established important risk factors of K. pneumoniae liver abscesses and of septic metastasis, and several recent studies have asserted that K. pneumoniae liver abscess might be a presentation of occult or silent colon cancer. We report a case of K. pneumoniae liver abscess, metastatic septic pulmonary embolism, and endophthalmitis associated with diabetes and advanced gastric cancer.

• Journal of Trauma and Injury
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• 제26권1호
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• pp.22-25
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• 2013

Severe blunt abdominal trauma frequently involves the liver. The development of nonsurgical treatment of liver trauma has led to more frequent appearance of unusual complications. A hepatic arterioportal fistula (APF) is a rare complication of liver trauma. We present a case of traumatic APF in a patient with liver trauma. A 31-year-old male visited our emergency department with pain in the right upper abdomen following a traffic accident. Initial physical exam and abdominal computed tomography (CT) revealed liver laceration with hemoperitoneum. An abdominal CT obtained on day 11 revealed early opacification of the right portal vein on the arterial phase. After we had come to suspect an APF of the liver, its presence was confirmed on angiography. It was subsequently managed by using transcatheter coil embolization. In patients with portal hypertension and no evidence or history of cirrhosis, one should consider an APF as a potential etiology if history of liver biopsy or penetrating trauma exists. In a patient with liver trauma, serial abdominal CT is important for early detection and treatment of an APF.

• Annals of Surgical Treatment and Research
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• 제95권6호
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• pp.333-339
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• 2018

Purpose: The purpose of this study was to describe the long-term effects of stenting in patients with hepatic venous outflow obstruction (HVOO), who underwent living donor liver transplantation (LDLT). Methods: Between January 2000 and December 2009, 622 adult patients underwent LDLT at our hospital, and of these patients, 21 (3.3%) were diagnosed with HVOO; among these patients, 17 underwent stenting. The patients were divided into early or late groups according to the time of their HVOO diagnoses (cutoff: 60 days after liver transplantation). Results: The median follow-up period was 54.2 months (range, 0.5-192.4 months). Stent insertion was successful in 8 of 10 patients in the early group and 6 of 7 in the late group. The 5-year primary patency rates were 46% and 20%, respectively. In both groups, patients with recurrent HVOO at the beginning showed kinking confirmed by venography. Patients who carried their stents for more than 3 years maintained long-term patency. There was no significant difference in spleen size between groups; however, when the groups were compared according to whether they maintained patency, spleens tended to be smaller in the patency-maintained group. Conclusion: Unlike stenosis, if kinking is confirmed on venography, stenting is not feasible in the long term for patients with LDLT.

• 대한수의학회지
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• 제31권1호
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• pp.109-121
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• 1991

소의 지방간(脂肪肝)의 이환율(罹患率)을 조사(調査)하고 fine needle aspiration biopsy에 의한 지방간(脂肪肝)의 세포학적진단(細胞學的診斷)을 시도(試圖)하였다. 육안적(肉眼的) 또는 부유법(浮遊法)에 의한 간장지방함량(肝臟脂肪含量)에 기초(基礎)한 소의 지방간(脂肪肝)의 발생율(發生率)은 한우(韓牛)암소에서 0.30%, 유우(乳牛)암소에서 4.70%, 유우(乳牛)숫소에서 0.15%였다. 지방간(脂肪肝)은 육안적(肉眼的) 소견(所見)으로 간장(肝臟)이 종대(腫大)되고 변연(邊緣)이 둔하며 가볍고 창백(蒼白)에서 주황색(朱黃色) 색조(色調)를 보이나 간장(肝臟)의 색조(色調)와 지방간(脂肪肝)의 중증도간(重症度間)에 환상(桓常) 상관관계(相關關係)가 인정(認定)되지는 않았다. 대부분의 정상간장(正常肝臟)과 중도(重度)의 지방간(脂肪肝)을 제외(除外)하고는 간장(肝臟)의 지방침윤(脂肪浸潤)은 중심정맥주위(中心靜脈周圍)에서는 거대지방구(巨大脂肪球)와 변연부(邊緣部)에서는 소지방구(小脂肪球) 그리고 맥관부(脈管部)에 지방침윤(脂肪浸潤)의 소견(所見)을 보였다. 부유법(浮遊法)에 의한 간장지방함량(肝臟脂肪含量)과 비교(比較)한 세포학상(細胞學上)의 민감도(敏感度), 특이도(特異度), 정확도(正確度)는 정상(正常)에서 94.4%, 95.2%, 94.9%, 경도(輕度)에서 64.3%, 100%, 87.2%, 중등도(中等度)에서 100%, 83.39%, 82.2%, 그리고 중도(重度)에서 모두 100%였다. 세포학적(細胞學的) 소견(所見)은 조직학적(組織學的) 소견(所見)과 잘 일치(一致)하였다. Fine needle aspiraton biopsy에 의한 합병증(合倂症)은 임상적(臨床的)으로 인지(認知)되지 않았다. 결론적(結論的)으로 needle aspiration biopsy에 의한 세포학적(細胞學的) 진단(診斷)은 소의 지방간(脂肪肝) 진단(診斷)에 있어서 조직학적(組織學的) 기법(技法)과 비교(比較)했을 때 단순(單純)하고 신속(迅速)하며 안전(安全)하며 경제적(經濟的)인 방법(方法)으로 사료(思料)된다.

• Journal of Nutrition and Health
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• 제41권7호
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• pp.583-593
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• 2008

This study was designed to examine the effects of Salicornia herbacea L. (glasswort: GW) on hepatic antioxidative enzyme activities in diabetic rats. Diabetes mellitus was induced in male Sprague-Dawley rats weighing 200-220g by an injection of streptozotocin (STZ) dissolved in a citrate buffer into the tail vein at a dose of 45 mg/kg of body weight. Sprague-Dawley rats were fed an AIN-93 recommended diet and the experimental groups were fed a modified diet containing 10% and 20% of glasswort powder for 4 weeks. The experimental groups were divided into 6 groups which consisted of normal (N)-control group, N-GW 10% and N-GW 20% treated groups, STZ-control, STZ-GW 10% and STZ-GW 20% treated groups. The activities of Xanthine oxidase (XOD), glutathione- S-transferase (GST), glutathione peroxidase (GPX), glutathione reductase (GR), superoxide dismutase (SOD) and CAT (CAT) were measured in the homogenates of liver. The activity of CAT was lower in the supplementary group with glasswort compare to the STZcontrol group but it was not significantly different. The activity of SOD was not significant in all of experimental groups. The activity of GR was significantly increased in the normal supplementary group with glasswort, and GPX activity was significantly increased in STZ-GW 10% group compare to the STZ-control group. The activity of XOD was significantly decreased in the all of supplementary groups with glasswort. The activity of GST was significantly increased in the N-GW 20% group and it was significantly decreased in the STZ-GW 20% group. These results show that the supplementation of glasswort may have favorable influence on antioxidative status in diabetic rats and it may be useful for the diabetic complications as functional food.

• Journal of Chest Surgery
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• 제35권3호
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• pp.239-243
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• 2002

본 증례의 39세 남자는 전신부종과 간부전증을 일으키는 Budd-Chiari syndrome과 상대정맥 폐색증을 가지고 입원하였다. 보존적 내과 치료 후 방사선과의 침습적 방법에 의한 확장술에 실패하여 하공정맥-우심방 단락술을 시행하였다. 수술은 정중흉골 절제술 및 직사행 복부 절제술을 통하여 직경 24 mm의 Dacron graft를 사용하여 좌신정맥 하에서 하공정맥-우심방 단락술을 체외순환을 하지 않고 시행하였다 수술후 출혈이나 합병증없이 양호한 결과를 보였으며 수술당일부터 항응고제 치료를 병행하였다. 술후 26일째 시행한 복부 도플러 초음파 상에서 graft의 유통성이 양호함을 확인하였다. 퇴원시 상대정맥 폐색 증상은 남아 있었으나 외래 추적 검사시 상대정맥 폐색 증상도 호전되었음을 확인할 수 있었다