• Journal of Life Science
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• v.21 no.4
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• pp.515-520
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• 2011

This study was carried out to evaluate the immunomodulatory capacity of edible mushrooms, including Lepista nuda, Corprinis comatus, Letinus edodes, and Pleurotus eryngii, in mice. BALB/c mice were administered 1, 50, and 500 mg/kg body weight of various mushrooms five times a week over 4 weeks through gastric intubation. The control mice were administered distilled water. No significant changes in body weight were observed. IL-4 and IFN${\gamma}$ production was evaluated with splenic T lymphocytes stimulated in vitro with phytohemagglutinins for 48 hr. The mice group administered L. edodes showed significantly higher ratio of IFN${\gamma}$ versus IL-4 than the other groups. In addition, the ratio of plasma IgG2a versus IgG1 was also significantly elevated in mice treated with L. edodes. However, no significant change was observed in ratio of IgG2a versus IgG1 in splenic B lymphocytes stimulated in vitro with lipopolysaccharides for 7 days. These results indicate that L. edodes can enhance type-1 helper T cell-mediated cellular immunity.

• Cartoon and Animation Studies
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• s.41
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• pp.107-131
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• 2015

This study is on the modification of characters' role and personality between spin-off animation and original works. For this, one of box office hits, (2011) and (2015) have been analyzed with Enneagram and Greimas' Actantial model. The result shows, firstly, the protagonist of spin-off work plays subject role in a new narrative comparing that he/she plays faithful helper's role in original work. Secondly, the protagonist's personality does not show big difference between in spin-off and in original. But, anyway, there's a small change that the secondary personality in original stands out as a primary personality in spin-off. Finally, the standing out personality of the protagonist tends to be 'achiever' or 'loyalist', those of stereotype successful animation characters. In conclusion, the role change according to new narrative seems to be unavoidable. And, the personality change is, too. However, the personality change is partial and it has continuity from the original considering the potential audiences' expectation.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.4
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• pp.924-933
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• 1999

This study investigated the effects of vitamin E supplementation on immune responses and antioxidant status in healthy Korean old and young women. Blood samples were obtained from 15 healthy old women (over 60 years old) and from 15 healthy young women(20 years old) before and 4 weeks after vitamin E( tocopherol acetate) supplementation(400IU/day). Daily nutrient intakes were calculated, and plasma vitamin E concentration, numbers and percentages of white blood cell and their subpopulation, percentages of lymphocytes and subpopulation, NK cell percentages, plasma immunoglobulin A, G, M and C3 concentration, proliferation of PMN with mitogen were measured. Also plasma TBARS concentration and radical scavenger activity of erythrocytes were investigated. Plasma vitamin E concentrations were significantly increased after supplementation in both groups. In elderly women, vitamin E supplementation restored the per centages of neutrophils, lymphocytes, and eosinophils which had been out of normal ranges before supple mentation. And after vitamin E supplementation, helper T cell percentages significantly increased in elderly. Plasma immunoglobulin and complement C3 concentrations were not affected by vitamin E supplementation in both groups. PMN proliferations with mitogen were significantly lower in old women than in young women, and there was no effect of vitamin E supplementation. Vitamin E supplementation significantly decreased plasma TBARS concentrations in old and young women. RSA of erythrocytes was increased in both groups, but the statistical significant was only found in young women group. Therefore, these results suggest that the moderate vitamin E supplementation in old women improves immune responses, especially nonspecific immunity and cell mediated immunity, via protection of oxidant stress.

• YAKHAK HOEJI
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• v.46 no.4
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• pp.258-264
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• 2002

Zinc plays an important role in immunobiological responses, while excessive zinc attenuates immune functions in a dose-dependent manner. Zinc excess has been reported to increase levels of plasma prostaglandin E$_2$ (PGE$_2$), which is known to inhibit production of Th (helper T) 1-associated cytokines and to induce inflammatory responses. Thus, this study was investigated the effects of indomethacin, a potent inhibitor of PGE$_2$ synthesis, on the proinflammatory cytokine and lymphokine production in ICR mice exposed to excessive zinc. Indomethacin at doses of 5 mg/kg was administered i.p. 30 minutes before zinc chloride (Zn) 30 mg/kg orally daily for 10 days. Excessive Zn remarkedly increased tumor necrosis factor (TNF)-$\alpha$ and interleukin (IL)-1$\beta$ levels in both serum and splenic supernatants compared with those in controls, while indomethacin significantly reduced the excessive Zn-induced levels of IL-1$\beta$. In serum, excessive Zn significantly decreased the levels of IL-2 and interferon (IFN)-${\gamma}$ compared with those in controls, whereas indomethacin significantly enhanced the excessive Zn-decreased levels of IFN-${\gamma}$ but did not affect the Zn-decreased levels of serum IL-2. In splenic supernatants, All of excessive Zn, indomethacin, and combination of Zn and indomethacin significantly enhanced IL-2 levels compared with those in controls, but indomethacin didn't affect the Zn-induced production of IL-2. These data, therefore, suggest that indomethacin significantly attenuated the in vivo and ex vivo IL-1$\beta$ production increased by excessive zinc and remarkedly enhanced the in vivo excessive zinc-suppressed production of IFN-${\gamma}$ but not IL-2.

• Journal of Korean Academy of Nursing
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• v.46 no.1
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• pp.39-49
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• 2016

Purpose: This study was done to develop a postural-stability patient transfer technique for care helpers in nursing homes and to evaluate its effectiveness. Methods: Four types of patient transfer techniques (Lifting towards the head board of the bed, turning to the lateral position, sitting upright on the bed, transferring from wheel chair to bed) were practiced in accordance with the following three methods; Care helpers habitually used transfer methods (Method 1), patient transfer methods according to care helper standard textbooks (Method 2), and a method developed by the author ensuring postural-stability (Method 3). The care helpers' muscle activity and four joint angles were measured. The collected data were analyzed using the program SPSS Statistic 21.0. To differentiate the muscle activity and joint angle, the Friedman test was executed and the post-hoc analysis was conducted using the Wilcoxon Signed Rank test. Results: Muscle activity was significantly lower during Method 3 compared to Methods 1 and 2. In addition, the joint angle was significantly lower for the knee and shoulder joint angle while performing Method 3 compared to Methods 1 and 2. Discussion: Findings indicate that using postural-stability patient transfer techniques can contribute to the prevention of musculoskeletal disease which care helpers suffer from due to physically demanding patient care in nursing homes.

• Journal of Korean Academy of Nursing
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• v.46 no.6
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• pp.836-847
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• 2016

Purpose: The purpose of this study was to examine the association between utilization of home care services under the national long-term care insurance system and family caregiver distress. Methods: A secondary data analysis was conducted in this study using data collected in 2011 and 2012 from the Korean version of International Resident Assessment Instrument (interRAI) Home Care assessment system. The study sample included 228 clients receiving community based home care and their family caregivers in Korea. Descriptive statistics, $x^2$ test, t-test, and Heckman selection model analysis were conducted using SAS 9.3. Results: Presence of family caregiver distress was significantly associated with days of nurse visits (${\beta}$=-.89, p=<.001) and home helper visits (${\beta}$=-.53, p=.014). Level of caregiver distress was also significantly associated with days of nurse visits (${\beta}$=-.66, p=.028). Other factors which were significantly associated with caregiver distress were depression, cognitive function, inadequate pain control, social support for older adult, and caregiver relationship to the older adult. Conclusion: The results of this study show that visiting nurse service and appropriate support programs for Older Adults and family caregivers experiencing caregiver distress should be developed and provided to families based on the health care needs of older adults and their family caregivers for effective and sustainable home care.

• Journal of Periodontal and Implant Science
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• v.40 no.2
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• pp.61-68
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• 2010

Purpose: The present study was performed to clarify the relationship between periodontal disease severity and selected immunological parameters consisting of serum IgG titer against periodontopathogenic bacteria, the expression of the helper T-cell cytokine by gingival mononuclear cells, and patients' immunoreactivity to cross-reactive heat shock protein (HSP) epitope peptide from P. gingivalis HSP60. Methods: Twenty-five patients with moderate periodontitis had their gingival connective tissue harvested of gingival mononuclear cells during an open flap debridement procedure and peripheral blood was drawn by venipuncture to collect serum. The mean level of interproximal alveolar bone was calculated to be used as an index for periodontal disease severity for a given patient. Each of selected immunologic parameters was subject to statistical management to seek their correlations with the severity of periodontal disease. Results: A significant correlation could not be identified between serum IgG titers against specific bacteria (Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Actinobacillus actinomycetemcomitans, and Streptococcus mutans) and the severity of periodontal disease. Expression of interleukin (IL)-10 by gingival mononuclear cells was statistically significant in the group of patients who had higher levels of alveolar bone height. However, a similar correlation could not be demonstrated in cases for IL-4 or interferon-$\gamma$. Patients' serum reactivity to cross-reactive epitope peptide showed a significant correlation with the amount of alveolar bone. Conclusions: It was concluded that expression of IL-10 by gingival mononuclear cells and patients' sero-reactivity to the cross-reactive HSP peptide of P. gingivalis HSP60 were significantly correlated with alveolar bone height.

• Journal of the Korean Home Economics Association
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• v.42 no.9
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• pp.111-134
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• 2004

The purpose of this dissertation is firstly to examine the level of pro-environmental behavior of urban employed wives depending on their life style type and secondly to identify effective ways to promote their pro-environmental behavior. A structured questionnaire interview was conducted with 700 urban employed wives who lived in the Seoul Metropolitan area, and 566 of the responses were valid for analysis. For statistical analysis, this research reviewed the frequencies, percentage, mean, standard deviation(SD), Pearson's correlations, Cronbach's u, factor analysis, cluster analysis, ANOVA, $\chi$$^2$-test, Duncan's Multiple Range Test, and multiple regression using SPSS/PC WIN. The findings of analysis of the study are as follows: 1. Among life style types of employed wives, the order of ecological value was orientation type (37.3%), followed by economical value orientation type (25.8%), uninterested type (18.7%), and convenience-centric value orientation type (18.2%).Pro-environmental behavior scored relatively highly at 3.45 in average. 2. In the analysis of the relationship between life style and background variations, every variation except environmental knowledge was meaningful. 3. In the relationship between pro-environment behavior and background variations, every variation was meaningful except housing types, having helper or not, and environmental knowledge. 4. The recognition level of environmental pollution was important among the variations affecting pro-environmental behavior. 5. There was a difference in pro-environmental behaviors by the following life style types: ecological value orientation, economical value orientation, convenience centric orientation and uninterested. 6. For the relative contribution comparison of background variations (socio-economic variation and environmental variation) and life style variations to the pro-environmental behavior of urban empolyed wives, this research additionally applied each independent variable group. As a result, the explanation level drastically increased in the third step that analyzed the relationship with life style.

• Journal of Korean Home Economics Education Association
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• v.18 no.3 s.41
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• pp.163-173
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• 2006

The purpose of this study was to investigate the marital satisfaction and family strengths in dual-Income teachers. The subjects of this study were 289 dual-income teachers in the Gyeongnam Area. Korea. The major findings obtained from this study are summarized as follows: 1) The degree of marital satisfaction of the dual-Income teachers was 5.22 on a scale of 0-7.0. The significant variables were sex, the educational degree, religion, the type of family. housework-helper, self-esteem and job satisfaction in dual-Income teachers. 2) The degree of family strengths of dual-Income teachers was 3.88 on a scale 0-5.0. The significant variables were economic level, self-esteem, job satisfaction, and marital satisfaction in dual-Income teachers. 3) There was a close correlation between the marital satisfaction and family strengths in dual-Income teachers.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.7
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• pp.1565-1570
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• 2014

In networking communication, nodes and base station send data to each nodes and destination nodes. In this perspective, it is very important to determine the direction in which data sent to each nodes or destination nodes. Ad-hoc routing protocol is a standard routing protocol that determines how the packets sent to destination. Ad-hoc routing protocol includes protocols such as Ad-hoc On-demand Distance Vector (AODV) and Dynamic Source Routing (DSR). In our efficient proposed protocol based on small end-to-end sequence numbers, route direction can be changed properly with the assistance of helper nodes. In this paper, we focus on the simulation analysis of proposed protocol and comparison with other routing protocol models such as AODV and DSR. We simulated using Network Simulator (NS-2) by parameters such as simulation time, number of nodes and packet size based on our metrics (packet delivery fraction, routing load, data throughput). Our proposed protocol based on small end-to-end sequence numbers shows better performance and superior to other two protocols.