• Journal of Veterinary Clinics
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• v.19 no.3
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• pp.375-378
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• 2002

A 3-year-old intact female korean pungsan dog showing chronic intermittent vomiting and anorexia was admitted to The Veterinary Medical leaching Hospital of Seoul National University. The patient had been received antiemetics, antacids or proton pump inhibitor for these symptoms but had not been recovered yet. All results of physical examination, complete blood count, serum chemical analysis, fecal test and radiography were normal. Gastric endoscopic examination was also performed and gastritis with hemorrhage on near antrum region was detected. In PCR assay of bioptic gastric tissues for detecting Helicobacter species infection, Helicobacter heilmannii infection was confirmed. After receiving triple therapy with amoxicillin, metronidazole and omeprazole for 21 days, all symptoms were recovered and had not been occurred again. Helicobacter heilmannii also were not detected.

• Korean Journal of Veterinary Research
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• v.40 no.4
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• pp.747-753
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• 2000

Helicobacter species have commonly been isolated from the gastric mucosa of humans and animals, however have not been known its association with clinical signs. This study was aimed to detect and identify Helicobacter species in the canine stomach by urease test and polymerase chain reaction(PCR). A total of 87 dogs in Kangwon and Kyunggi areas from August, 1998 to June, 1999 were examined. The detection rate of Helicobacter species by urease test for fundal biopsy samples was 83.9%, and positive rate was increased as incubation time was increased. Helicobacter species was detected in the seventy seven dogs(88.5%) of total 87 dogs by PCR. The fifty five strains of the 77 strains of Helicobacter species were identified as H heilmannii and the three strains were identified as H felis by PCR, but the nineteen strains were not identified.