• 한국자기공명학회논문지
• /
• 제12권1호
• /
• pp.40-50
• /
• 2008

Ghrelin is a unique peptide hormone that releases growth factor and it stimulates appetite. It comes from pre pro-ghrelin by the post translational modification process and its innate functions are known as food up-take and the growth hormone regulation. Therefore, the structural information of ghrelin precursor is of importance in understanding it function. From our results, we found that the solution structure of ghrelin is mostly random coil conformation at neutral pH value and the structural population changes with pH environments. Data from circular dichroism in different TFE concentrations revealed that the secondary structure changes from random coil to a-helix and the isodichroic point is observed at 202nm, implying that two equilibrium states exist between random coil and helical structure.

• 대한화학회지
• /
• 제39권10호
• /
• pp.776-782
• /
• 1995

.alpha. 트로포마이신솨 파라마이신등은 .alpha. 나선-사슬이합체를 이룰수 있다. 사슬이합체의 나선에서 코일로의 전이 현상을 적절이 설명할수 있는 이론을 얻을 수 있었다. 이전의 이론은 Zimm-Bragg 매개변수를 사용하는 행렬식으로 올리고펩티드 사슬 이합체의 전이를 설명하였지만 이 이론으로는 올리고펩티드에서 무시할 수 없는 dangling H-bond를 고려할 수 없었다. 본 이론에서는 dangling H-bond까지 고려할수 있는 zipper 모형을 사용하였다. 나선도를 단일 사슬에서 사용되는 나선 개시상수(.sigma.), 나선 안정화(.zeta.)와 소수성상호 인력 매개변수(.omega.) 등의 함수로서 계산할 수 있었다. .alpha. 트로포마이신에서 나선 안정화의 경향을 계산 하였다. 이 올리고펩티드의 온도, 올리고펩티드의 온도, 올리고펩티드농도 변화에 의한 전이는 사슬의 해리와 동시에 일어난다. S-S 결합 등으로 이어진 사슬이 합체나 긴 사슬을 가지는 폴리펩티드는 항상 나선구조로 존재하여 전이가 일어나기 힘들다. 올리고펩티드의 농도에 의한 전이는 사슬의 길이 또는 온도계에 의한 전이보다 급격함을 알 수 있었다.

• Nuclear Engineering and Technology
• /
• 제52권12호
• /
• pp.2699-2708
• /
• 2020

Helical-coil steam generator (HCSG) technology is a major design candidate for small modular reactors due to its compactness and capability to produce superheated steam with high generation efficiency. In this paper, we investigate the feasibility of the passively autonomous power maneuvering by coupling the 3-D transient multi-physics of a soluble-boron-free (SBF) core with a time-dependent HCSG model. The predictor corrector quasi-static method was used to reduce the cost of the transient 3-D neutronic solution. In the numerical system simulations, the feedwater flow rate to the secondary of the HCSGs is adjusted to extract the demanded power from the primary loop. This varies the coolant temperature at the inlet of the SBF core, which governs the passively autonomous power maneuvering due to the strongly negative coolant reactivity feedback. Here, we simulate a 100-50-100 load-follow operation with a 5%/minute power ramping speed to investigate the feasibility of the passively autonomous load-follow in a 450 MW_th SBF PWR. In addition, the passively autonomous frequency control operation is investigated. The various system models are coupled, and they are solved by an in-house Fortran-95 code. The results of this work demonstrate constant steam temperature in the secondary side and limited variation of the primary coolant temperature. Meanwhile, the variations of the core axial shape index and the core power peaking are sufficiently small.

• 대한치과교정학회지
• /
• 제21권2호
• /
• pp.353-366
• /
• 1991

This study was performed to analyze the effects of forces to the alveolar bone by various molar uprighting spring such as helical uprighting spring. T-loop spring, Modified T-loop spring and open coil spring. The simplified two-dimensional photoelastic model was constructed with a lower left posterior quadrant containing the second molar, the first and second premolars and the canine, with the first molar missing. Several molar uprighting springs were fabricated from 0.017 by 0.022 inch blue Elgiloy and applied to the photoelastic model. Two-dimensional photoelastic stress analysis was performed, and the stress distribution was recorded by photography The results obtained were as follows; 1. In all the kinds of the springs, the center of rotation of the mandibular second molar was oserved at the apical 1/5-1/6 between the alveolar crest and the root apex. 2. In all the kinds of the spring, the stress induced in the mesial root surface of the mandibular second molar was relatively homogeneous but there was some difference in the magnitude of the stress. 3. In the kinds of the springs, the distal crown tipping moment of the second molar was increased in turn as open coil spring, helical uprighting spring, T-loop spring, and modified T-loop spring. 4. The largest extrusive force was occured in the T-loop spring, intrusive force was occured in Modified T-loop spring only, and the largest distal tipping force was occured in open coil spring. 5. In the T-loop spring with activation, the stress induced in the mesial root surface of the second molar was increased gradually from the root apex to the alveolar crest and highly concentrated in the alveolar crest.

• 한국추진공학회지
• /
• 제24권3호
• /
• pp.59-70
• /
• 2020

본 논문에서는 기존 적층형 배관의 총 열전달 계수 경험식을 활용할 때 발생하는 한계점을 해결하고자, 외부 총 열전달 계수의 강제 대류 열전달 계수 항을 독립적으로 도출하는 간소화된 모델링을 제안하고, 이를 극저온 환경의 실험 결과로 확인하였다. 액체 산소 냉각 나선형 열교환기가 액체 질소와 열교환하는 실험 장치를 구성하고 열교환기의 열전달량을 계측하여, 외부 총 열전달 계수를 도출하였다. 측정된 외부 총 열전달 계수가 모델링으로 예측 곡선과 일치함을 확인하였다.

• Nuclear Engineering and Technology
• /
• 제49권8호
• /
• pp.1669-1679
• /
• 2017

Background: Steam generator (SG) is one of the significant components in the nuclear steam supply system. A variety of SGs have been designed and used in nuclear reactor systems. Every SG has advantages and disadvantages. A brief account of some of the existing SG designs is presented in this study. A high surface to volume ratio of a SG is required in small modular reactors to occupy the least space. In this paper, performance improvement for SGs of integral small modular reactor is proposed. Aims/Methods: For this purpose, cross-grooved microfins have been incorporated on the inner surface of the helical tube to enhance heat transfer. The primary objective of this work is to investigate thermal-hydraulic behavior of the proposed improvements through modeling in RELAP5-3D. Results and Conclusions: The results are compared with helical-coiled SGs being used in IRIS (International Reactor Innovative and Secure). The results show that the tube length reduces up to 11.56% keeping thermal and hydraulic conditions fixed. In the case of fixed size, the steam outlet temperature increases from 590.1 K to 597.0 K and the capability of power transfer from primary to secondary also increases. However, these advantages are associated with some extra pressure drop, which has to be compensated.

• 한국전자파학회논문지
• /
• 제22권10호
• /
• pp.999-1004
• /
• 2011

본 논문에서는 무선 전력 전송 시스템에서 널리 사용되는 원형 코일 사이의 상호 인덕턴스 계산 방법과 이를 이용한 해석 결과를 제시한다. 두 원형 코일은 수직으로 배열되었다. 상호 인덕턴스 계산을 위해 수직 배열된 수전부 원형 코일의 면적을 일정한 높이의 단위 셀로 나누고, 각 단위 셀에 쇄교하는 자속 밀도를 구하여 상호인덕턴스를 계산하였다. 이를 위해 두 원형 코일을 필라멘트 코일로 모델링하였고, 각 코일에서의 전류는 균일 하다고 하였다. 검증을 위해 헬리컬, 스파이럴 형태로 두 원형 코일을 제작하였고, z 방향의 간격이 50~100 cm인 구간에서 상호 인덕턴스를 측정한 결과, 본 논문에서 제시한 이론값과 일치하였다.

• 대한설비공학회:학술대회논문집
• /
• 대한설비공학회 2007년도 하계학술발표대회 논문집
• /
• pp.12-12
• /
• 2007

• Bulletin of the Korean Chemical Society
• /
• 제17권2호
• /
• pp.131-138
• /
• 1996

The conformational transition of oligopeptide multimer,-(HPPHPPP)n-, is studied (H:hydrophobic amino acid, P:hydrophilic amino acid). The helix/coil transitions are detected in the multimer. The transition depends on the number of amino acid in the sequence, the concentration of the oligopeptide, and temperature which affects helix stability constant (${\xi}$) and hydrophobic interaction parameter (wj). In the thermodynamic equilibrium system jA${\rightarrow}$Aj (where A stands for oligopeptide monomer), Skolnick et al., explained helix/coil transition of dimer by the matrix method using Zimm-Bragg parameters ${\xi}$ and $\sigma$ (helix initiation constant). But the matrix method do not fully explain dangling H-bond effects which are important in oligopeptide systems. In this study we propose a general theory of conformational transitions of oligopeptides in which dimer, trimer, or higher multimer coexists. The partition of trimer is derived by using zipper model which account for dangling H-bond effects. The transitions of multimers which have cross-linked S-S bonds or long chains do not occur, because they keep always helical structures. The transitions due to the concentration of the oligopeptides are steeper than those due to the chain length or temperature.

• 센서학회지
• /
• 제8권4호
• /
• pp.298-307
• /
• 1999

This paper describes the application of the coupled FE-BEM (finite element-boundary element method) for the numerical harmonic analysis of the linear dynamic behaviour of a magnetostrictive Terfenol-D rod in water. The magnetostrictive rod is three-dimensionally simulated to transduce applied electric current in a helical coil around the rod to mechanical displacement. The theoretical derivation of the magnetostrictive matrix equation is described in detail. The steady-state resonance response of the displacement is shown. In addition, the directivity pattern and the radiation impedance are also shown.