• Journal of the Korean Institute of Gas
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• v.13 no.3
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• pp.49-53
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• 2009

Relief systems can improve the process safety because it has the function for the prevention of overpressure. Flare stacks is necessary to avoid explosion, radiation, or toxicity by waste-gas emitted from relief system. Safe combustion is one of the important factors to improve safety and the quantity and velocity emitted is ruled in the API code 521. Due to the pressure of released gas and mass flow, a flame from flare stack is similar to jet fire. In this study, we have investigated the effect of flame form on complete combustion and heat emission. API code was similar to jet fire model in flame length, the flame had an effect on the ground.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3471-3476
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• 2012

Background and Objective: Histone deacetylase (HDAC) inhibitors represent a promising class of potential anticancer agents for treatment of human malignancies. In this study, we investigated the effect of trichostatin A (TSA), one such HDAC inhibitor, in combination with docetaxel (TXT), a cytotoxic chemotherapy agent or erlotinib, a novel molecular target therapy drug, on lung cancer A549 cells. Methods: A549 cells were treated with TXT, erlotinib alone or in combination with TSA, respectively. Cell viability, apoptosis, and cell cycle distribution were evaluated using MTT (3- (4, 5-dimethylthiazol-2-yl) -2, 5-diphenyltetrazolium bromide) assay, Hochst33258 staining and flow cytometry. Moreover, immunofluorescent staining and Western blot analysis were employed to examine alterations of ${\alpha}$-tubulin, heat shock protein 90 (hsp90), epidermal growth factor receptor (EGFR), and caspase-3 in response to the different exogenous stimuli. Results: Compared with single-agent treatment, co-treatment of A549 cells with TSA/TXT or TSA/erlotinib synergistically inhibited cell proliferation, induced apoptosis, and caused cell cycle delay at the $G_2/M$ transition. Treatment with TSA/TXT or TSA/erlotinib led to a significant increase of cleaved caspase-3 expression, also resulting in elevated acetylation of ${\alpha}$-tubulin or hsp90 and decreased expression of EGFR, which was negatively associated with the level of acetylated hsp90. Conclusions: Synergistic anti-tumor effects are observed between TXT or erlotinib and TSA on lung cancer cells. Such combinations may provide a more effective strategy for treating human lung cancer.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.9
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• pp.1700-1710
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• 1992

The boundary element method is applied to determine thermal stress intensity factors for a cusp crack in transient state. In the steady temperature field, numerical values of thermal stress intensity factors for a Grifith crack and a symmetric lip cusp crack in a finite body are in good agreement within .+-. 5% with the previous solutions. In transient state, the numerical values of thermal stress intensity factors for the Griffith crack are also in good agreement with the pervious solutions. In both steady and transient states, those for the symmetric lip cusp crack with the crack surface insulated or fixed to the constant temperature are calculates for various effective crack lengths, configuration parameters and uniform heat flow angles. The variations of the thermal boundary conditions of the crack surface have a effect on stress intensity factors. The signs on the values of thermal stress intensity factors can be changed in time variation.

• Journal of Energy Engineering
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• v.24 no.2
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• pp.72-78
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• 2015

In the present study, a recuperator to improve the thermal efficiency of a micro gas turbine is considered. The counter flow plate-fin heat exchanger with offset strip fins is chosen as the type of the recuperator. From the optimization study as varying design parameters of the recuperator determined from the ideal cycle analysis, the internal structure of the recuperator is determined. The recuperator is made from stainless steel 304. In order to evaluate performance of the recuperator, experimental investigation is performed. The effects of inlet temperature of hot-side of the recuperator on the thermal performance of the recuperator are investigated. As a result, effectiveness of the recuperator obtained from the experiments is well consistent with that obtained from the correlations.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.8
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• pp.749-754
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• 2010

Knowledge of the characteristics of airflow in nasal cavities is essential to understand the physiological and pathological aspects of nasal breathing. In our laboratory, a series of experimental investigations on the nasal airflow was conducted; airflow in models of normal and deformed nasal cavities under both constant and periodic flow conditions was studied by PIV. Some of the patients with asymmetric nasal cavities experience pain or discomfort, while other patients with asymmetric nasal cavities do not experience pain. Airflows inside asymmetric nasal cavities with and without obstructions due to a bent nasal septum are investigated both experimentally by PIV and numerically by using the general-purpose FVM code in order to determine the reason for the above-mentioned discrepancy. The comparisons between two cases are tried. Heat and humidity distribution are investigated numerically.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.11
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• pp.1091-1097
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• 2017

Sales of commercial-type cooling fans intended for application in military electronics are often discontinued during equipment production. This results in requirements for alternative fan selection as well as equipment performance and reliability tests, such as high-temperature operation testing. This study deals with alternative fan selection and verification methods that can be used during the production process. First, an alternative fan was selected by calculating the flow and pressure required to effectively cool the equipment, then the feasibility of the selected fan was verified using a reliable CFD heat dissipation analysis model. Following this, a high-temperature operation test was performed using the alternative fan in the equipment. Results demonstrated that the equipment satisfied its required function in a high-temperature environment, and the main parts as well as internal air temperature were found to be thermally stable.

• Journal of the Korean Society of Propulsion Engineers
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• v.20 no.6
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• pp.46-53
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• 2016

It is required to predict a limit cycle amplitude controlled by system's nonlinear behavior as well as an eigen-frequency and initial growth rate of instabilities under the linear motions, in order to fully understand combustion instabilities in a lean premixed gas turbine combustor. Special focus of the current work is placed on the limit cycle amplitude prediction using flame describing function(FDF) where the ratio of a heat release fluctuation to a given flow perturbation is expressed as a function of frequency and amplitude. In this study, the CFD modeling work based on RANS is carried out to obtain FDF, which makes that the nonlinear thermo-acoustic model is successfully developed for predicting the limit cycle amplitude of the combustion instability.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.19 no.12
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• pp.842-849
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• 2007

For a $CO_2$ two-stage twin rotary compressor used for heat pump water heater system, changes of $CO_2$ solubility in PAG oil were investigated along the gas passages from the first stage suction to final discharge. Only slight changes in solubility took place in suction chambers for both of the first and second stages, but for compression chambers, solubility variation ranged from 0.115 to 0.136, and from 0.133 to 0.182, respectively for the first and second stages. Calculation of gas flashing in parts of leakage oil flows and of oil contained in control volumes due to solubility changes was conducted and included in gas pressure calculation. For the second stage, gas flashing amounts to around $5%\sim6%$ for most leakage flows. Cooling capacity, compressor input, and COP obtained by calculation were well compared to the experimental results. Effects of operation speed on the compressor performance was also studied: as the shaft speed increased, adiabatic efficiency decreased rapidly due to increased over-compression loss.

• Proceedings of the SAREK Conference
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• 2008.06a
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• pp.304-308
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• 2008

The optimal design of two stage evaporation & absorption system which is related to the large temperature difference system was investigated numerically in the absorption refrigeration system. The concentrations at inlet & oulet of absorber are 62.9% and 56.9%, but in two stage absorption system the values are 62.2% and 56.2%. Therefore strong solution & weak solution became diluted than the standard value. The amount of weak solution circulation can be reduced in absorption refrigeration system, and the sensible heat load is more reduced to enhance the COP of system. As UAR is increased, COP becomes larger, and this means the role of top section is more important than bottom section in two stage evaporation & absorption system. But the increase of COP becomes slower at 0.7 of UAR ratio. The performance of Type2 is higher than Type1 in COP with the flow direction of cooling waters. This phenomena is due to the active absorption of vapor -absorption & lower temp. cooling water is more effective. The pressure at bottom section becomes higher & that at top section becomes lower and therefore the circulation rate can be diminished more.

• Nuclear Engineering and Technology
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• v.23 no.2
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• pp.183-199
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• 1991

Transient response of temperature distributions in a Pressurized Water Reactor (PWR) pressurizer vessel wall for the Inadvertent Auxiliary Spray transient has been analyzed with conservatism accounted for the resulting thermal stresses in the regions of the vessel wall which are wetted by the spray water droplets. In order to determine the forced convective heat transfer coefficient at the inner boundary surface of vessel wall where the droplets impinge on and flow down, the transient temperatures of spray droplets when they reach the inner surface of the vessel wall after travelling from the spray nozzle through the pressurizer interior space occupied with the saturated steam-noncondensable hydrogen gas mixture have been predicted. The transient temperature distributions in the vessel wall have been obtained by using the finite element method, and the typical results have been provided. It has been shown that the results of thermal analysis are consistent with representation of the input transient and have plausible physical meaning.