• Korean Journal of Radiology
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• 제2권1호
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• pp.21-27
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• 2001

Objective: To identify and evaluate the lateral border zone by comparing the size and distribution of the abnormal signal area demonstrated by MR imaging with the infarct area revealed by pathological examination in a reperfused myocardial infarction cat model. Materials and Methods: In eight cats, the left anterior descending coronary artery was occluded for 90 minutes, and this was followed by 90 minutes of reperfusion. ECG-triggered breath-hold turbo spin-echo T2-weighted MR images were initially obtained along the short axis of the heart before the administration of contrast media. After the injection of Gadomer-17 and Gadophrin-2, contrast-enhanced T1-weighted MR images were obtained for three hours. The size of the abnormal signal area seen on each image was compared with that of the infarct area after TTC staining. To assess ultrastructural changes in the myocardium at the infarct area, lateral border zone and normal myocardium, electron microscopic examination was performed. Results: The high signal area seen on T2-weighted images and the enhanced area seen on Gadomer-17-enhanced T1WI were larger than the enhanced area on Gadophrin-2-enhanced T1WI and the infarct area revealed by TTC staining; the difference was expressed as a percentage of the size of the total left ventricle mass (T2= 39.2 %; Gadomer-17 =37.25 % vs Gadophrin-2 = 29.6 %; TTC staining = 28.2 %; p < 0.05). The ultrastructural changes seen at the lateral border zone were compatible with reversible myocardial damage. Conclusion: In a reperfused myocardial infarction cat model, the presence and size of the lateral border zone can be determined by means of Gadomer-17- and Gadophrin-2-enhanced MR imaging.

• 대한자기공명의과학회:학술대회논문집
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• 대한자기공명의과학회 1998년도 제3차 추계학술대회 초록집
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• pp.114-118
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• 1998

• Journal of Cardiovascular Imaging
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• 제31권1호
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• pp.51-61
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• 2023

BACKGROUND: Valvular heart disease (VHD) is a common cause of cardiovascular morbidity and mortality worldwide; however, its epidemiological profile in Korea requires elucidation. METHODS: In this nationwide retrospective cohort study from the Korean valve survey, which collected clinical and echocardiographic data on VHD from 45 medical centers, we identified 4,089 patients with VHD between September and October 2019. RESULTS: The aortic valve was the most commonly affected valve (n = 1,956 [47.8%]), followed by the mitral valve (n = 1,598 [39.1%]) and tricuspid valve (n = 1,172 [28.6%]). There were 1,188 cases of aortic stenosis (AS) and 926 cases of aortic regurgitation. The most common etiology of AS was degenerative disease (78.9%). The proportion of AS increased with age and accounted for the largest proportion of VHD in patients aged 80-89 years. There were 1,384 cases of mitral regurgitation (MR) and 244 cases of mitral stenosis (MS). The most common etiologies for primary and secondary MR were degenerative disease (44.3%) and non-ischemic heart disease (63.0%), respectively, whereas rheumatic disease (74.6%) was the predominant cause of MS. There were 1,172 tricuspid regurgitation (TR) cases, of which 46.9% were isolated and 53.1% were associated with other valvular diseases, most commonly with MR. The most common type of TR was secondary (90.2%), while primary accounted for 6.1%. CONCLUSIONS: This report demonstrates the current epidemiological status of VHD in Korea. The results of this study can be used as fundamental data for developing Korean guidelines for VHD.

• Journal of Korean Neurosurgical Society
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• 제30권3호
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• pp.389-394
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• 2001

경막정맥동 혈전증은 다양한 원인을 가진 비교적 드문 질환으로 알려져왔으며 임상양상 및 발현형태가 매우 다양하여 임상적 진단이 쉽지 않았다. 그러나 최근에는 여러 영상진단 방법, 특히 자기공명영상 혈관 촬영등을 통해 조기 진단이 가능하게되었다. 치료 방법을 결정할 때, 환자의 임상증상과 정맥순환계의 개인간 차이가 매우 중요한 인자중 하나이다. 저자들은 보존적 치료로 좋은 결과를 얻은 2례의 경막정맥동 환자의 특성을 문헌고찰과 함께 보고하는 바이다.

• 대한영상의학회지
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• 제79권5호
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• pp.294-301
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• 2018

상의하세포종은 드문 중추신경계 종양으로 두개내 발생하는 종양의 0.7%를 차지한다. 두개내 상의하세포종은 위치에 따라 특징적인 MR 소견을 보여주는데 가끔 비전형적인 소견도 존재할 수 있다. 또한 매우 드물게는 척수내에 발생하기도 한다. 우리는 각각 뇌실내 위치에도 불구하고 비전형적인 소견을 보인 경우와 드물게 척수 내에 나타난 상의하세포종의 경우, 두 가지 조직학적으로 확진된 상의하세포종 증례를 소개하고 그 임상적 증상과 영상학적 소견에 대해 고찰하려고 한다.

• Journal of Chest Surgery
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• 제27권8호
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• pp.656-663
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• 1994

Evaluation of heart function is of importance in assessing the results of valvular heart surgery. Information on volume and functional change of heart chamber can be obtained by cardiac catheterization and echocardiography. We studied 41 patients with mitral stenosis[MS] and 23 patients with mitral regurgitation[MR] using M-mode echocardiography before and after mitral valve replacement[MVR] at Pusan Paik Hospital. Preoperative cardiac catheterization was available in 56 cases, and the results were obtained as follows. 1. In patients with MS, preoperative average LV end-diastolic dimension[EDD] and end-systolic dimension[ESD] were remained within normal range, but postoperative EDD and ESD were significantly decreased[P<0.01]. The preoperative and postoperative LV ejection fraction[EF] were remained within the normal range and no significant change[P>0.05]. The preoperative left atrial dimension[LAD] was enlarged considerably above normal[P<0.01], but was significantly decreased after surgery[P<0.001]. The preoperative LV posterior wall thickness[PWTh] was within normal range, and no significant change after surgery[P>0.05]. 2. In patients with MR, preoperative average end-diastolic dimension[EDD] and end-systolic dimension[ESD] were significantly greater than normal[P<005], but postoperative EDD and ESD were significantly decreased[P<0.01]. The preoperative LV ejection fraction[EF] and fractional shortening[FS] were within normal range, and no significant change after surgery[P>0.05].The preoperative left atrial dimension[LAD] was enlarged considerably above normal [P<0.01], but was significantly decreased after surgery[P<0.001].The preoperative LV posterior wall thickness[PWTh] was within normal range, and no significant change after surgery[P>0.05].

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제22권6호
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• pp.594-600
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• 2019

With improving survival of children with complex congenital heart disease (CCHD), postoperative complications, like protein-losing enteropathy (PLE) are increasingly encountered. A 3-year-old girl with surgically corrected CCHD (ventricular inversion/L-transposition of the great arteries, ventricular septal defect, pulmonary atresia, postdouble switch procedure [Rastelli and Glenn]) developed chylothoraces. She was treated with pleurodesis, thoracic duct ligation and subsequently developed chylous ascites and PLE (serum albumin ${\leq}0.9g/dL$) and was malnourished, despite nutritional rehabilitation. Lymphangioscintigraphy/single-photon emission computed tomography showed lymphatic obstruction at the cisterna chyli level. A segmental chyle leak and chylous lymphangiectasia were confirmed by gastrointestinal endoscopy, magnetic resonance (MR) enterography, and MR lymphangiography. Selective glue embolization of leaking intestinal lymphatic trunks led to prompt reversal of PLE. Serum albumin level and weight gain markedly improved and have been maintained for over 3 years. Selective interventional embolization reversed this devastating lymphatic complication of surgically corrected CCHD.

• 대한한방소아과학회지
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• 제22권1호
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• pp.13-24
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• 2008

Objectives This study was designed to analyze the clinical studies on Mental retardation(MR) in traditional Chinese medicine(TCM). Methods For this study, we searched the clinical studies on MR, which had been published from 2003 to 2007, through web site CNKI(中國知識基礎設施工 http://www.cnki.net). There were 17 clinical studies and we focused on those studies. Results 1. In those Chinese studies, they used following words to describe Mental retardation; 小人弱智($xi\check{a}o\acute{e}rru\grave{o}zh\grave{i}$), 智能發育不全($zh\grave{i}n\acute{e}ngf\bar{a}y\grave{u}buqu\acute{a}n$), 智力低下($zh\grave{i}l\grave{i}d\bar{i}xi\grave{a}$), 精神發育遲滯($j\bar{i}ngsh\acute{e}f\bar{a}y\grave{u}ch\acute{i}zh\grave{i}$), 智能落后($zh\grave{i}n\acute{e}nglu\grave{o}h\grave{o}u$), 智能落后($zh\grave{i}n\acute{e}ngch\acute{i}hu\check{a}n$), 失天愚型患人($xi\bar{a}nti\bar{a}ny\acute{u}x\acute{i}nghu\grave{a}n'\acute{e}r$). 2. There were many kinds of TCM treatment methods for MR, such as herbal medicine, acupuncture, electroacupunture, acupoint injection, Chuna therapy, and special education. And those TCM treatments methods showed higher efficacies in the treatment of MR compared with Western medicine. 3. Mental retardation was related with the deficiency of heart, kidney, liver, spleen(心虛, 腎虛, 肝虛, 脾虛) and the pathological mechanism of Phlegm(絹) and Blood stasis(慫沂)in the studies about the Bian Zheng-the types of differential diagnosis- of MR. 4. Most of studies used Intelligence Quotient(IQ) to assess the efficacy of TCM treatment of MR. And the duration of treatment, the degree of illness, the age of patient, and the cause of illness affected the prognosis of MR. Conclusions These results suggest that traditional medicine could be one of the useful treatments on MR. And these results could be used in the clinical practices and studies on MR in Korea.

• 한국의학물리학회지:의학물리
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• 제13권4호
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• pp.224-228
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• 2002

MR영상에 Spatial Modulation of Magnetization (SPAMM)과 같은 lagging 기법을 이용하여 심근의 움직임을 분석하여 임상에 적용하려는 많은 노력들이 이루어지고 있다. Tagging 대조도는 자동 tagline 검출 알고리즘을 사용하는 경우, 그 정확도에 영향을 미칠 수 있으며, 이는 tagline들 간의 간격에 의해 영향을 받을 수 있다. 본 연구의 목적은 SPAMM 영상에서 tagline 간격과 tagging 대조도와의 관계를 생체내 연구를 통해 알아보고자 하였다. 두 명의 건강한 지원자를 대상으로 1.5T MR 시스템에서 SPAMM 기반의 ECG triggered MR 영상을 획득하였다. 영상을 획득할 때, 먼저 3.6 mm에서 9.6 mm 사이의 간격을 가지는 수평 tagging stripe pattern의 tagline을 가하였다. 심실의 영상은 심장주기가 진행되는 동안 field echo EPI (FE-EPI) 기법을 이용하여 심실 중간 부분에서 얻었다 각 영상에 대한 tagging contrast-to-noise ratio (CNR)는 IDL을 이용한 프로그램을 사용하여 측정하였다. 분석 결과는, 심근의 수축이 진행되는 동안, tagline 간격이 좁은 경우 CNR은 급격한 감소를 나타내었으나, 간격이 넓은 경우에서는 CNR 감소 현상이 보이지 않았다. 같은 심장 위상에서, CNR은 tagline 간격이 넓어짐에 따라 증가하는 경향을 보였다. 특히, 완전히 수축한 심장 위상에서는, CNR의 변화가 다른 위상일 때와 비교해서 그 증가율이 높음을 알 수 있었다. 이러한 양상은 움직임이 없는 다른 주변 조직에서는 관찰되지 않았다. 결론적으로, 본 연구에서는 lagging 대조도가 tagline 간격 및 심근의 수축에 영향을 받을 수 있음을 알 수 있었으며, 앞으로 정확한 심근 움직임 연구를 위한 기초 자료로 쓰여질 수 있을 것이라 생각된다.

• Journal of Chest Surgery
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• 제30권6호
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• pp.598-606
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• 1997

1994년 9월부러 1995년 8월까지 일년동안 부천 세종병원에서 시행된 승모판막질환 수술은 총 136례였으 며 이중 인공판륜을 사용하여 판막성형술을 시행된 44례를 대상으로 평가하였다 이 44례의 평균 연령은 38.2세(범위: 5세~63세)였으며 남성이 18례 여성이 26례였다, 사용된 인공판륜은 Carpentier ring이 32례, Dmm ring 이 12례였다. 판막질환의 원인은 류마치스가 30례(68%), 퇴행성 질환에 기인한 것이 13례(30%)였으며, 1례는 선천성 승 모판 부전증이었다. 판막질환의 형태로 보면 승모판막부전증이 33례(76%),승모판 협착증이 2 례(5%), 승모판 협착부전증이 9례(19%) 있었다. Carpentier의 기능적 분류는 I형이 5례(11%), II형이 24례(55%), III형이 4례(9%) 있었으며, II형과 III형의 혼합형이 11례(25%)에서 관찰되었고, 매 환자당 평균 3.7가지의 병변이 있었다. 승모판에 시행한 수술 수기는 전례에서 인공판륜성형술을 시행하였으며 한 환자 당 평균 3.4가지의 수기 를 사용하였다. 수술 사망은 2례에서 발생하였으며, 수술 후 승모판 부전증이 진행되어 2주에 시행한 재수술이 일 례 있 었다. 12개월의 추적 관찰에서 수술 전후의 NYHA 기능적 鈞畢\ulcorner평균 3.0에서 1.3으로 개선되었다. 심장 초음파 검사에서 술후의 승모판 면적은 2.07$\pm$0.11 cm2(평균 $\pm$ 표준오차)이었으며, 좌심실 수축력의 호전을 보였고, 판막부전의 정도는 전혀 판막부전 소견이 없어진 경우가 23례(53%), 경미한 폐쇄부전이 있는 경우가 18례(42%)였고, II도 부전의 소견을 보인 례가 2례(5%) 있었다.