Journal of Cardiovascular Imaging

Korean Society of Echocardiography (한국심초음파학회)
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Epidemiologic Profile of Patients With Valvular Heart Disease in Korea: A Nationwide Hospital-Based Registry Study

  • You-Jung Choi (Division of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Korea University) ;
  • Jung-Woo Son (Division of Cardiology, Department of Internal Medicine, Yonsei University, Wonju College of Medicine) ;
  • Eun Kyoung Kim (Division of Cardiology, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • In-Cheol Kim (Division of Cardiology, Department of Internal Medicine, Cardiovascular Center, Keimyung University Dongsan Hospital) ;
  • Hyung Yoon Kim (Department of Cardiovascular Medicine, Chonnam National University Medical School and Hospital) ;
  • Jeong-Sook Seo (Division of Cardiology, Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University) ;
  • Byung Joo Sun (Division of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine) ;
  • Chi Young Shim (Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine) ;
  • Se-Jung Yoon (Division of Cardiology, National Health Insurance Service Ilsan Hospital) ;
  • Sahmin Lee (Division of Cardiology, Heart Institute, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Sun Hwa Lee (Division of Cardiology, Department of Internal Medicine, Jeonbuk National University Hospital, Jeonbuk National University Medical School) ;
  • Jun-Bean Park (Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital) ;
  • Duk-Hyun Kang (Division of Cardiology, Heart Institute, Asan Medical Center, University of Ulsan College of Medicine)
  • Received : 2022.06.20
  • Accepted : 2022.09.13
  • Published : 2023.01.27
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Abstract

BACKGROUND: Valvular heart disease (VHD) is a common cause of cardiovascular morbidity and mortality worldwide; however, its epidemiological profile in Korea requires elucidation. METHODS: In this nationwide retrospective cohort study from the Korean valve survey, which collected clinical and echocardiographic data on VHD from 45 medical centers, we identified 4,089 patients with VHD between September and October 2019. RESULTS: The aortic valve was the most commonly affected valve (n = 1,956 [47.8%]), followed by the mitral valve (n = 1,598 [39.1%]) and tricuspid valve (n = 1,172 [28.6%]). There were 1,188 cases of aortic stenosis (AS) and 926 cases of aortic regurgitation. The most common etiology of AS was degenerative disease (78.9%). The proportion of AS increased with age and accounted for the largest proportion of VHD in patients aged 80-89 years. There were 1,384 cases of mitral regurgitation (MR) and 244 cases of mitral stenosis (MS). The most common etiologies for primary and secondary MR were degenerative disease (44.3%) and non-ischemic heart disease (63.0%), respectively, whereas rheumatic disease (74.6%) was the predominant cause of MS. There were 1,172 tricuspid regurgitation (TR) cases, of which 46.9% were isolated and 53.1% were associated with other valvular diseases, most commonly with MR. The most common type of TR was secondary (90.2%), while primary accounted for 6.1%. CONCLUSIONS: This report demonstrates the current epidemiological status of VHD in Korea. The results of this study can be used as fundamental data for developing Korean guidelines for VHD.

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References

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