• 수면정신생리
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• 제12권1호
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• pp.45-49
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• 2005

연구목적：기면병 환자와 정상 대조군의 생물유전적 기질 및 성격을 비교하기 위한 연구를 시행하였다. 연구방법：국제 수면장애 분류에 따라 진단된 기면병 환자군 22명과 정상 대조군 22명을 대상으로 하였다. 각 군에게 한국어판 기질 및 성격 척도를 작성하도록 하고 그 결과를 비교하였다. 연구결과：정상 대조군에 비해 기면병 환자군은 유의하게 높은 새로운 것을 추구하는 경향(Novelty-Seeking)(ANCOVA, F=5.42, p=0.025), 낮은 완고한 경향(Persistence)(F=8.41, p=0.006), 그리고 낮은 자기중심성(Self-Directedness) (F=4.70, p=0.036)을 보였다. 결 론：기면병 환자들은 특유의 생물유전적 기질을 가지고 있다. 이 연구 결과는 기면병 환자들이 새로운 것에 대해 관심을 보이나 쉽게 포기하는 기질을 가지고 있다는 것을 제시한다. 또한, 이 연구 결과는 기면병 환자들이 비효율적이며, 무력하며, 상처 받기 쉬운 자아상을 가진다는 것을 나타낸다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권12호
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• pp.6295-6298
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• 2012

Oxidant/antioxidant balance has been suggested as an important factor for initiation and progression of cancer. The objective of this study was to determine changes in the levels of malondialdehyde (MDA), nitric oxide (NO), total cholesterol, triglycerides, LDL-cholesterol, HDL-cholesterol, total antioxidant capacity (TAC), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) activities in serum samples of breast cancer patients (n=30) and healthy subjects (n=100). MDA and NO levels were found to be increased in breast cancer patients compared to the healthy subject group (p<0.05). Total cholesterol and triglycerides were elevated; and HDL-cholesterol level was found to be decreased in the cancer patients as compared to the healthy subjects (p<0.05). Compared to the healthy group, both serum TAC levels (p<0.001) and activity of SOD and GSH-Px (p=0.05) were found to be decreased in the breast cancer patients as compared to the healthy controls. Considering the data presented in this study, we suggest that free radicals induce lipid eroxidation and peroxidation of unsaturated fatty acid with decreased activity of enzymatic antioxidants in breast cancer.

• 가정과삶의질연구
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• 제28권3호
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• pp.167-178
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• 2010

The purpose of this study was to analyze the healthy family education, healthy family counseling, a healthy family culture, and healthy families integrated programs for single parent families in family support centers, The data collected came from 59 family support centers located in Seoul and Kyunggi-Do, Korea. Subjects included both single parents and their children. The children were of elementary school age. The types of programs were education, counseling, culture, and integrated program. Education programs were process separately for the parents and for the children. Counseling programs were mostly group-type program that aimed at improving the parent-children relationship. The contents included sections on anger management, reducing stress, enriching self-esteem. The culture programs involved experiences, camps that included cooking, watching movies, similar activities. Integrated programs involved respite support, rearing support, mentor-mentee partnerships, and the formation of self-help groups.

• The Journal of Korean Physical Therapy
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• 제27권5호
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• pp.281-286
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• 2015

Purpose: The study was to determine whether mechanical horseback-riding training according to velocity may improve trunk muscles thickness in healthy adults. Methods: Twenty healthy adults participated in this study. The subjects were divided into 2 groups as follows: 10 subjects in high velocity mechanical horseback-riding training (MHRT) and 10 subjects in low velocity MHRT. Subjects in all groups performed a total of 18 sessions 3 times a day for 20 minutes and this experiment lasted for 6 weeks. Mann-Whitney and Wilcoxon Signed Rank test were used in analysis the results of trunk muscle thickness. Ultrasonography was performed to evaluate for thickness of rectus abdominis (RA), external oblique (EO), internal oblique (IO), transverse abdominis (TrA), erector spine (ES), and multifidus (MF) in trunk muscles. Results: Results on the changes of EO, IO, and ES of high velocity MHRT showed a significant increase after 6 weeks (p<0.05). Regarding the changes of EO, IO, ES, TrA, and MF of low velocity MHRT, a significant increase was observed after 6 weeks (p<0.05). The differences in change of trunk muscle thickness before training, after 6-week training between groups, TrA and MF of low velocity MHRT were significantly higher (p<0.05). Conclusion: Based on the results of the current study, the velocity of MHRT was shown to affect change of trunk muscle thickness in healthy adults. In particular, low velocity MHRT may serve as a useful method to provide for TrA, MF thickness improvement related to trunk stabilizers.

• Journal of Nutrition and Health
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• 제33권7호
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• pp.745-754
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• 2000

Effects of oral taurine supplementation (6g/day)for 2-4 weeks on activities of red blood cell(RBC)total superoxide dismutase (SOD) and plasma glutathione peroxidase(GSH-Px) and the level of malondialdehyde(MDA) were evaluated in healthy female adults (23.6$\pm$0.3 years old). Compared to the value for 0 week plasma GSH-Px activity of the subjects was significantly lower after 2 weeks of taurine supplementation(p<0.05) and recovered to the value similar to 0 week after 4 weeks of taurine supplementation. RBC total SOD activity tended to be decreased after 2 weeks of taurine supplmentation compared to the values for 0 week although the difference between the means of the two group was not statistically significant. Plasma MDA level was not significantly decreased by taurine supplementation most probably due to the fact that the subjects participated in the present study were healthy and their antioxidant defense system had been in the 'normal' range. Plasma MDA concentration was negatively correlated with plasma taurine concentration(r=-0.2003m p<0.05) but tended to be positively correlated with plasma cholesterol concentration(r=0.2465, p=0.0645) as expected Plasma GSH-Px activity was positively associated with the percentage of 22:0 (r=0.2892, p<0.05) or 20:4w6(r=0.2939, p<0.05). On the other hand plasma MDA concentration was positively correlated with the percentage of 20:5w3 in plasma total lipids(r=0.2635 p<0.05) and negatively correlated with $\Delta$5 desaturation index of w6 fatty acids(20:3w6⇒20:4w6) in plamsa total lipids(r=-0.2714, p<0.05) as well as in phospholipids(r=-0.2864, p<0.05). From these results protective effect of taurine supplementation against lipid peroxidation and antioxidant defense system in humans appears to be minimal when the subjects are in a relatively healthy state. Further studies concerning the antioxidant efficacy of taurine should be conducted in human subjects under various disease states related to oxidative stress such as diabetes and artheroxclerosis.

• 한국한의학연구원논문집
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• 제18권3호
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• pp.119-126
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• 2012

1. Objectives Sasang constitutional medicine is unique in Korean traditional medicine. It diagnoses and treats patients based on his/her Sasang constitution (SC). Skin properties have been used as an effective diagnostic component in the classification of SC types in clinics. In this paper, we investigated the SC-based health relevance of skin elasticity and wrinkle properties. 2. Methods The skin elasticity and wrinkle of forearm and dorsal hand were measured in 299 elderly female subjects. To determine the subject's Sasang constitution, we adopted the classification results from a newly developed SC diagnostic tool. The health states of the subjects were scored by two Korean traditional medical doctors, by whom each subject was categorized either into the healthy state or the unhealthy state. 3. Results As a result, the elasticity hysteresis of forearm (E_HYS), the visco-elasticity (VE_MEAN), and the wrinkle frequency energy of backhand (W_HAND) showed significant differences between Taeum-in group and Soeum-in group. In case of the Soeum-in on unhealthy state, VE_MEAN was decreased significantly (p<.05). W_HAND and W_ARM_H of the healthy Taeum-in were less than those of the unhealthy Taem-in. 4. Conclusions In this study we showed that, for an elderly female population, skin elasticity and viscosity were significantly different not only between each SC type but also between healthy group and unhealthy group in each constitution. In particular, Soeum-in subjects were inferred to be superior in retaining skin softness when they were healthy, and Taeum-in subjects were easy to lose their firmness of skin surface when they became unhealthy.

• 대한불안의학회지
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• 제10권2호
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• pp.143-150
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• 2014

Objective : The subgenual cingulate cortex, a part of default-mode network, has been known to playa key role in the pathophysiology of depression. The previous studies have reported abnormal functional connectivity between the subgenual cingulate cortex and other brain regions in the patients with depression. The goal of this shldy was to explore the resting-state functional connectivity of the subgenual cingulate cortex between the patients with depression and healthy subjects. Methods : Twenty patients with major depression and age- and sex-matched 20 healthy subjects underwent 5-minute resting state fMRI scans. The functional connectivity map in each subject was acquired using seed-based correlation analysis with the seed located in the subgenual cingulate cortex (Talairach coordinates; x=-10, y=5, z=-10). The functional connectivity maps were calculated using AFNI and compared between the patient and healthy subject group via two-sample T-test using 3dttest++ in AFNI package. Results : Functional connectivity was decreased between the subgenual cingulate cortex and both sides of fusiform gyrus in depressed subjects. Connectivity was also decreased between the subgenual cingulate cortex and the left cerebellum in the patient group. There was no correlation between the severity of depression and the degree of functional connectivity between the subgenual cingulate cortex and the regions showing decreased functional connectivity. Conclusion : Decreased resting-state functional connectivity between the subgenual cingulate cortex and both sides of fusiform gyrus, and decreased connectivity between the subgenual cingulate cortex and the left cerebellum found in the patients with major depression in comparison to the healthy subjects might be related to abnormal emotional and cognitive processing of depressed patients.

• 한국식품영양학회지
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• 제28권6호
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• pp.1056-1064
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• 2015

This study was designed to provide the basic data of an effective nutrition education for desirable lifestyle and dietary habits to improve the nutritional status for the elderly by investigating health-related lifestyle, dietary habits, nutritional knowledge, and food intake of the elderly. The subjects included 58 elderly men and 146 elderly women. 35.8% had no more than an elementary school education. Most subjects (54.4%) were widows/widowers. Most subjects (71.0%) made over 150,000 won. 52.5% of subjects lived in houses. Smoking, drinking, exercise, the average sleeping time were significantly difference between the gender (p<0.05). In terms of dietary habits, our results showed that 80.9% of respondent eat regularly meals, including breakfast (83.5%). Both sexes prefer soft and salty food. Women enjoys more spicy and salty food compared with men and then shows meaningful difference (p<0.05). Their favorite meals are soup, stew, salad and boiled vegetables. Compared to women, men have a higher rate of correct answers about questions related to nutrition knowledge as showing significantly difference (p<0.05). In a study of dietary habits, they take in carbohydrates with the highest percentage and following by vegetables and fruits. The amount of meat, first and egg they eat is more than the previously. Eating meat is higher men as showing significant difference (p<0.05). In summary, nutritional status for the elderly shows healthy lifestyle and diet about half of those and most them try to live healthy life in future. It is hope that the elderly may need to learn proper nutrition knowledge for healthy lifestyle and nutrition education and counseling for building up healthy lifestyle and desirable dietary habits. Furthermore, it is necessary to start work to establish a baseline nutritious evaluation for the elderly and at a time to study the development of standard eating tool proven reliability and validity, consequently to provide a basic framework for the evaluation of nutritional status.

• Journal of Acupuncture Research
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• 제30권4호
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• pp.1-14
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• 2013

Objectives : The purpose of this study is to investigate the effects of Sa-Am spleen-tonifying acupuncture on radial pulse in healthy human subjects. Methods : Forty healthy human subjects participated in this study, divided into acupuncture group and control group. Radial pulse was measured by 3 dimensional pulse imaging system(DMP-3000) before, right after, 30 minutes after and 60 minutes after acupuncture in the acupuncture group. The subjects in the control group didn't received acupuncture but took a rest and then the radial pulse was measured at the same time points as the acupuncture group. The parameters were analyzed by gender, measuring location, and measuring time point. However the time related parameters exceptionally were analyzed without distinction of measuring location. Results : 1. T, variance of period, T2/T, T4/T, (T-T4)/T, T4/(T-T4), and W significantly changed after acupuncture. 2. Pressure, amplitude of H1, amplitude of H2, Amplitude of H4 and pulse energy significantly changed after acupuncture. 3. Pulse area, systolic pulse area and diastolic pulse area significantly changed after acupuncture. 4. Elasticity, AIx and AIx/HR significantly changed after acupuncture. Conclusions : The effect of Sa-Am spleen-tonifying acupuncture in healthy human may be observed on time, amplitude, pulse area and augmentation index. Further studies on the effects of Sa-Am acupuncture using radial pulse are needed.

• Korean Journal of Acupuncture
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• 제24권3호
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• pp.105-116
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• 2007

Objectives : This study was performed to determine whether a pulse analyzer using array piezoresistive sensor was useful to characterize the variables of pulse wave of hypertentive patients (HT) , compared with those of healthy subjects. Methods : One hundred twenty two subjects participated in this study. Sixty nine subjects had hypertension and fifty three subjects had no specific history or disease associated with hypertension. We used automatic pulse analyzer with array piezoreslstive sensor. Results : Calibrated in Chon, no specific differences was between HT group and the healthy group. Calibrated in Gwan. sum of pulse pressure (SPP) of HT group was higher than that of the healthy group. Calibrated in Cheek, mean of height of main peak (Mm) and height of main peak (h1) of HT group were higher than those of the healthy group. Conclusions : Pulse analyzer was useful to determine the risk degree or development possibility of hypertension.