• Journal of Oral Medicine and Pain
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• 제15권1호
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• pp.37-44
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• 1991

The author has synchronously recorded average electromyographic activities of temporalis anteriors and masseter muscles and the maximum bite force on the mandibular first molar on the prferred chewing side. These activities were recorded in order to study the EMG activity pattern of the working side and the balancing side to maximum bete force and functioning state of muscle in 30 patients with TMD and in 30 healthy subjects as controls. The results were as follows : 1. The maximum bite force on the mandibular first molar on the preferred chewing side was 20.63kg in TMD patients and 53.30kg in the healthy subjects(p<0.01). The maximum bite force in TMD patients was 38.7% of the healthy subjects. 2. The average electromyographic activities of temporalis anterioris and masseter muscles on the working side and the balancing side during maximum bite force were lower in TMD patients than in the healthy subjects(p<0.01). The average electromyographic activities of each muscle in TMD patients were 61.0%-62.8% of the healthy subjects. 3. The proportionalities of average electromyographic activities of temporalis anteriors and masseter muscles on the working side and the balancing side to maximum bite force were greater in TMD patients than in the healthy subjects(p<0.01). 4. Between the working side and the balancing side, the proportionality of average electromyographic activity of temporalis anterior to maximum bite force on the working healthy subjects (p<0.01). The proportionality of average electromyographic activity of working side and the balancing side in both groups (p<0.05).

• 한국전문물리치료학회지
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• 제9권2호
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• pp.33-42
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• 2002

The purpose of this study was to compare the onset times of muscle activities and the order of muscle firing in hamstring gluteus maximus, and lumbar erector spinae muscle during active hip extension between subjects with low back pain (LBP) and healthy subjects. Thirty subjects, 15 with LBP and 15 healthy subjects, participated in this study. Electromyographic activity was recorded during active hip extension in prone and standing position. Relative onset times of these muscle activities were determined. Similar muscle firing order in hamstring, gluteus maximus, and lumbar erector spinae muscle showed in both groups and positions. However, the onset time of gluteus maximus was significantly later in prone and standing active hip extension in subjects with LBP than in healthy subjects. The onset time of lumber erector spinae muscle activity was significantly delayed in subjects with LBP in standing active hip extension, The delayed onset times of gluteus maximus and lumbar erector spinae muscles' activities were probably related to LBP. Further studies are needed to identify whether the delayed onset times of gluteus maximus and lumbar erector spinae muscle activities are the contributing factors to LBP.

• 대한물리의학회지
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• 제7권4호
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• pp.423-432
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• 2012

PURPOSE: The purpose of this study was to investigate balance changes in young patients with neck pain by comparing postural sway velocity and velocity moment between young patients with neck pain and healthy subjects. METHODS: The cross-sectional study enrolled fifteen young patients with over 3-month duration of the neck pain and twelve healthy subjects between the ages of 20 and 30 years old. All subjects were measured their postural sway velocity and velocity moment during quiet standing with eyes open and eyes closed conditions. We compared the differences of postural sway velocity and velocity moment between neck pain patients and healthy subjects, and between eye open and eye close. RESULTS: Significant differences were evident in the anteroposterior and mediolateral sway velocity, and velocity moment of center-of-pressure (COP) between patients with neck pain and healthy subjects (p<.05), and in patients with neck pain in the eyes open and eyes closed conditions (p<.05). CONCLUSION: These results indicate that the balance of young patients with neck pain was worse than healthy subjects during quiet standing, and was especially lessened in the absence of vision. The finding may inform management program to decrease the balance deficits in young patients with neck pain.

• Journal of Periodontal and Implant Science
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• 제47권3호
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• pp.174-181
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• 2017

Purpose: Epitope spreading is a phenomenon in which distinct subdominant epitopes become major targets of the immune response. Heat shock protein (HSP) 60 from Porphyromonas gingivalis (PgHSP60) and peptide 19 from PgHSP60 (Pep19) are immunodominant epitopes in autoimmune disease patients, including those with periodontitis. It remains unclear whether Pep19 is a dominant epitope in subjects without periodontitis or autoimmune disease. The purpose of this study was to determine the epitope spreading pattern and verify Pep19 as an immunodominant epitope in healthy teenagers using dot immunoblot analysis. The patterns of epitope spreading in age-matched patients with type 1 diabetes mellitus (type 1 DM) and healthy 20- to 29-year old subjects were compared with those of healthy teenagers. Methods: Peptide from PgHSP60, Mycobacterium tuberculosis HSP60 (MtHSP60), and Chlamydia pneumoniae HSP60 (CpHSP60) was synthesized for comparative recognition by sera from healthy subjects and patients with autoimmune disease (type 1 DM). Dot immunoblot analysis against a panel of peptides of PgHSP60 and human HSP60 (HuHSP60) was performed to identify epitope spreading, and a densitometric image analysis was conducted. Results: Of the peptide from PgHSP60, MtHSP60, and CpHSP60, PgHSP60 was the predominant epitope and was most consistently recognized by the serum samples of healthy teenagers. Most sera from healthy subjects and patients with type 1 DM reacted more strongly with PgHSP60 and Pep19 than the other peptides. The relative intensity of antibody reactivity to Pep19 was higher in the type 1 DM group than in the healthy groups. Conclusions: Pep19 is an immunodominant epitope, not only in autoimmune disease patients, but also in healthy young subjects, as evidenced by their robust immunoreactivity. This result suggests that the Pep19-specific immune response may be an initiator that triggers autoimmune diseases.

• Journal of Nutrition and Health
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• 제39권8호
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• pp.832-840
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• 2006

This study was performed to investigate the relationship between diet quality and food cost and identify the effects of food cost on healthy diet among Korean adult. Among the subjects of 2001 National Health and Nutrition Survey 1,641 men and 1,765 women aged from 30 to 49 years were selected and their information of dietary intakes, socio-demo-graphic information, and anthropometric data were analyzed. For the analysis, subjects were classified to quartile based on their daily food cost. Food guidelines provided by Korean Nutrition Society was regarded as a model of healthy diet. Subjects in the lowest quartile of food cost consumed inadequate amount of food from all food categories of the guidelines. Many subjects in the highest quartile not only satisfied the recommended amount of the Food Guide but also seemed to overeat high energy density foods. Even in the highest quartile, about 90% of subjects did not satisfied recommended amount of dairy products. According to the calculated cost of healthy diet, the average cost did not seem to be more expensive than the current mean food cost of the subjects, and most cost-sensitive food intake was observed in the meat fish beans eggs category. The implications of study results were: 1) all the high cost diets did not indicate the high quality of diet, 2) most practical matter of healthy diet in low income group seemed whether they could afford the expense of meat and fish, 3) nutrition education was required to most subjects for healthy diet.

• 한국식품영양학회지
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• 제30권1호
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• pp.83-95
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• 2017

This study examined the socioeconomic factors that affect self-rated health (SRH) in healthy adults, and the relationship of SRH to health-related habits, serum biochemical indices, and nutritional intakes. Subjects consisted of 1,154 healthy adults without any known disease, aged 19 to 65 years (average age of 36.7), whose information was obtained from the 2013 Korean National Health and Nutritional Examination Survey data. Of these subjects, 73 rated themselves as 'very healthy,' 460 indicated that they were 'healthy,' 568 self-identified as 'ordinary', and 53 put themselves in the 'unhealthy' category. The proportion of subjects who chose 'unhealthy' was significantly increased with higher frequencies of disruptions in their daily lives (p<0.05), regret after drinking (p<0.05), smoking (p<0.001), and higher levels of stress (p<0.001). On the other hand, the proportion of subjects reported as 'very healthy' was significantly higher with regular intense (p<0.001) or moderate physical activities (p<0.05), regular walking (p<0.05), a perception of being 'normal' in their body image (p<0.01), a decrease of body weight more than 3 kg in the past year (p<0.05), and without risk factors for metabolic syndrome (p<0.05). Serum triglyceride level was lower, and 25-(OH) vitamin D content was significantly higher, in the 'very healthy' group as compared to the 'unhealthy' group (p<0.05). Dietary fiber and vitamin C intakes were significantly higher in the 'very healthy' group than 'unhealthy' group (p<0.05). The overall results suggest that a healthy lifestyle, including regular exercise, non-smoking, good stress management, and higher intakes of fiber and vitamin C, may be potential factors that affect one's positive perception of health.

• The Journal of Korean Physical Therapy
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• 제21권1호
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• pp.73-80
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• 2009

Purpose: In order to examine difference in the activity of potential of spinal neurons and cortical neurons according to muscle contraction type in post stroke hemiplegic subjects and healthy subjects, the present study conducted an experiment as follows. Methods: The subjects in the experimental group were 17 left-side hemiplegic subjects (9 female, 8 male; mean age, 63.41$\pm$9.86 years) with the right hand as the dominant hand selected among post stroke hemiplegic subjects, and 17 age matched healthy control subjects (10 female, 7 male; mean age, 64.12$\pm$12.07 years). Movement-related cortical potentials (MRCPs) were measured using surface electromyography and electroencephalography while concentric and eccentric movements were made alternately. Results: As to the pattern of the activity of MRCP, which indicates the activity of motor cortical neurons, we found that the amplitude is high (p<0.01), the length of excitement is short (p<0.01) and the ascending gradient of amplitude to the peak increases (p<0.05) in post stroke hemiplegic subjects' lesion sites different from healthy subjects. Conclusion: The activity of cortical neurons was no difference in activity according to contraction type was observed in post stroke hemiplegic subjects' lesion sites. This suggests that there is no distinction in the activity of cortical neurons between concentric contraction and eccentric contraction. Accordingly, if post stroke hemiplegic subjects' activity of motor cortex is analyzed by measuring MRCPs, it is considered useful in research on neural plasticity or as a ground of clinical effects in the area of physical therapy for the central nervous system.

• Allergy, Asthma & Immunology Research
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• 제10권6호
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• pp.662-674
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• 2018

Purpose: Group 2 innate lymphoid cells (ILC2s) have been implicated in the pathogenesis of allergic disease. However, the effect of allergen-specific immunotherapy (AIT) on ILCs remains to be clarified. The aim of this study was to evaluate the levels of ILC subsets in allergic rhinitis (AR) patients in response to house dust mite (HDM)-specific immunotherapy. Methods: We enrolled 37 AR patients undergoing AIT (16 responders and 11 non-responders) for 2 years, 35 HDM AR patients and 28 healthy subjects. Peripheral blood mononuclear cells (PBMCs) were analyzed by flow cytometry to identify ILC subsets. Stimulation of ILC2s with recombinant allergen-specific protein was used to determine ILC2's activation (CD69 expression). Results: Responder AIT patients and healthy subjects had a decreased frequency of circulating ILC2s compared to non-responder AIT and AR patients. Conversely, ILC1s from responder AIT patients and healthy subjects showed increased frequency compared to non-responder AIT and AR patients. The frequency of ILC3s natural cytotoxicity receptor $(NCR)^+$ and $NCR^-$ in responder AIT patients was significantly lower compared to AR patients and healthy subjects. The ILC1: ILC2 proportion in responder AIT patients was similar to that of healthy subjects. PBMCs from patients who were responders to AIT had a significantly lower expression of the activation marker CD69 on ILC2s in response to allergen re-stimulation compared to AR patients, but no difference compared to non-responder AIT patients and healthy subjects. Conclusions: We propose that AIT might affect ILC responses. The activation of ILC2s was reduced in AR patients treated with AIT. Our results indicate that a relative ILC1/ILC2 skewed response is a possible key to successful AIT.

• 동아시아식생활학회지
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• 제19권4호
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• pp.515-524
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• 2009

This study was a preliminary investigation of healthy breads in the domestic bakery industry and examined conditions for consumer purchases. The analyzed data will be used for future product improvements within for the domestic bakery market. The key results were as follows: First, the subjects' choosing of healthy breads was 'Usually' (34.1%) and women were more knowledgeable about healthy breads than men. About 31.2% of the subjects responded 'Do not know well', but 98% had clear purchase intentions and showed positive acclaims for healthy breads. Second, the ranking of selection factors that subjects considered when buying healthy breads was 'curiosity>taste>safety>health>price>diet>employee representation> brand'. Women (3.89) had more sensitive reactions than men (3.47) to the 'Diet' variable, and there were statistical differences in 'Health', 'Taste', and 'Employee explanation' (p<0.05, p<0.001). Finally, highly educated considered brand more (3.87).

• PNF and Movement
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• 제12권1호
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• pp.39-43
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• 2014

Purpose: This study was to examine lateral abdominal muscle activation during maximum expiration exercise between healthy and chronic low back pain(CLBP) patients. Methods: The subjects were 16 CLBP patients and 16 healthy people between the ages of 22 and 53. The thickness of the abdominal muscles was measured using ultrasonography(LOGIQ Book XP, GE, USA). We instructed the subjects how to perform the exercises and measured changes in thickness of the transversus abdominis(TrA) and internal oblique(IO) muscles during the maximum expiration. The main outcome variables were the ratios of the TrA and IO thickness during the exercise versus in the relaxed position(TrA and IO activation ratios). Results: There were significant differences between CLBP patients and healthy subjects for TrA in the relaxed position. However there was no difference in the ratio of change in the muscle activity(TrA, IO). Conclusion: These findings, CLBP patients exhibited atrophy of the TrA muscle, but voluntary TrA muscle activation was similar to that of the normal subjects. Therefore, this exercise could be used during core strengthening in CLBP patients.