• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제31권6호
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• pp.481-491
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• 2005

Purpose: The aim of the present study is to evaluate the effect of autogenous bone and allograft material coverd with a bioresorbable membrane on bone regeneration after a simultaneous installation of implant. Materials and methods: Twelve healthy rabbits, weighing about $3{\sim}4$ kg, were used in this experiment. Following impalnt(with 3.25 mm diameter and 8 mm length) site preparation by surgical protocol of $Oraltronics^{(R)}$, artificial bony defect, 5mm sized in height and depth, was created on femoral condyle using trephine drill(with 5 mm diameter and 5 mm length). Then implant was inserted. In the experimental group A, the bony defect was filled with autogenous particulated bone and coverd with $Lyoplant^{(R)}$ resorbable membrane. In the experimental group B, the bony defect was filled with allograft material(Orthoblast $II^{(R)}$) containing demineralized bone matrix and covered with $Lyoplant^{(R)}$. In the control group, without any graft materials, the bony defect was covered with $Lyoplant^{(R)}$. The experimental group A and B were divided into each 9 cases and control group into 3 cases. The experimental animals were sacrificed at 3, 6 and 8 weeks after surgery and block specimens were obtained. With histologic and histomorphometric analysis, we observed the histologic changes of the cells and bone formation after H-E staining and then, measured BIC and bone density with KAPPA Image $Base^{(R)}$ system. Results: As a result of this experiment, bone formation and active remodeling process were examined in all experimental groups and the control. But, the ability of bone formation of the experimental group A was somewhat better than any other groups. Especially bone to-implant contact fraction ranged from 12.7% to 43.45% in the autogenous bone group and from 9.02% to 29.83% in DBM group, at 3 and 8 weeks. But, bone density ranged from 15.67% to 23.17% in the autogenous bone group and from 25.95% to 46.06% in DBM group at 3 and 6 weeks, respectively. Although the bone density of DBM group was better than that of autogenous bone group at 3 and 6weeks, the latter was better than the former at 8 weeks, 54.3% and 45.1%, respectively. Therefore these results showed that DBM enhanced the density of newly formed bone at least initially.

• 대한의용생체공학회:의공학회지
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• 제24권4호
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• pp.241-246
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• 2003

정상 성인을 대상으로 언어생성과제의 시각적 지시과제와 청각적 지시과제에 대한 기능적 MR영상들을 비교하고자 하였다. 6명의 정상 성인을 대상으로 자기공명영상기기를 이용하였다 시각적, 청각적 언어 지시과제는 명사의 언어를 이용하여. 휴지기. 확성기를 각각 6번 구성하였다. 뇌의 활성영역의 휴지기와 확성기의 신호변화에 따른 데이터는 MRDx 프로그램으로 처리하였고 cross correlation 방법으로 통계 처리하였다. 시각적, 청각적 지시과제의 분석방법은 lateralization index 공식으로 뇌 반구의 활성화 voxel의 총합과 좌$.$우 반구의 픽셀 수를 구하였고, 지시 과제에 대한 활성화 영역을 “Area of Activation Cells” 값에 따라 4등급으로 분류하여 비교 분석하였다. 시간적 청각적 지시과제에서 Broca, Wernicke 영역 등에서 크기는 다르지만 모두 활성화가 관찰되었다. lateralization index에서 뇌반구의 활성화 값에 차이는 시각적 지시과제에 비해 청각적 지시과제가 높은 활성화 값을 보였다. 그러므로 언어영역에 대한 뇌의 기능적 영상을 얻는데 두 방법 모두 유용하다고 생각된다.

• 대한원격탐사학회지
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• 제30권5호
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• pp.665-675
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• 2014

본 연구에서는 소나무재선충병이 확산되어 있는 거제도를 대상으로 소나무재선충병 감염목 특성분석을 위하여 지상용 초분광 카메라를 활용하여 2012년과 2013년에 걸쳐 대상 임목을 촬영하였다. 영상 촬영은 소나무재선충병이 확산되는 시기인 6~9월 기간에 개체목 단위와 임분 단위로 구분하여, 개체목은 인위적으로 소나무재선충병을 주입한 공시목을 대상으로 실시하고, 임분은 소나무재선충병이 자연적으로 발생한 임분을 대상으로 실시하였다. 수백개의 파장대역 정보를 담고 있는 지상용 초분광 영상을 이용하여 소나무재선충병 감염단계에서부터 고사단계에 이르기까지 파장대역 변화와 특성분석을 진행하였다. 그 결과, 전체 파장대역 중 적색영역(550~700 nm)의 변화가 두드러지게 나타났으며 특히, 688 nm 전후의 파장대역에서 고사목과 정상목간의 가장 많은 변화폭이 관측되었다. 향후 초분광 항공사진을 활용한 소나무재선충병 감염목 탐지 활용가능성 판단을 위하여 개체목 단위 촬영영상보다 대면적의 임분단위 촬영영상을 활용한 분석이 진행되었다. 가장 큰 변화를 나타낸 688 nm 구간의 식생지수 활용을 위하여 Normalized Difference Vegetation Index(NDVI), Red Edge Normalized Difference Vegetation Index(reNDVI), Photochemical Reflectance Index(PRI), Anthocyanin Reflectance Index 2(ARI2) 식생지수에 대한 비교 분석을 실시하였다. 감염목 탐지에 효율성이 높다고 판단되는 지수는 NDVI와 reNDVI으로 나타났으며 688 nm를 NDVI와 reNDVI식 적색영역에 적용한 결과 688 nm를 포함하여 적용한 지수값에서 감염진행에 따른 가장 큰 변화폭을 나타내어 감염목 탐지에 가장 효율적인 것으로 판단되었다.

• 유통과학연구
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• 제12권8호
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• pp.17-29
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• 2014

Purpose - The use of corporate social activities to implement the concept of corporate social responsibility enhances brand equity and attitude, and strengthens economic competitiveness. In areas such as mobile communications, companies take the responsibility of protecting customers and enhance the quality of the mobile communication service, helping to make an effort to obey the regulations of the public trade order and fair trade agreement, enabling a healthy society through communication with elderly living alone or youths without parents, and enhancing marketing strategies. Research design, data, and methodology - To test the hypothesis, a survey was conducted. The surveyed population includes people who use the big three mobile communication services. The survey was conducted from October 4th to October 14th, 2013. A total of 500 survey questionnaires were circulated and 483 were collected; out of these, 32 were excluded due to missing or incomprehensible information. The data was analyzed with SPSS 18.0 via frequency analysis, trust analysis, search factor analysis, relationship analysis, confirmation factor analysis using AMOS 18.0, and structural equation model analysis. Results - Research on corporate social responsibility has been frequently conducted recently. Companies are perceived as social constituents satisfying the social desires of people in addition to customer needs. Further, companies are returning profits to society to satisfy community needs, because there is greater emphasis on the social responsibilities of companies. Companies' social responsibilities should include marketing strategies and the identification of customer needs. This study shows that social service activities influence brand value, which influences customer attitudes; therefore, social service activities indirectly influence customer attitudes. In order to increase customers' purchasing intention, it is essential to improve brand image via social services and provide a distinctive quality of service. Conclusions - This research has used the purposive selection method in the empirical analysis to identify the effect of social services on brand value and customer attitude. Therefore, this study revealed that businesses, whose ultimate objective is to improve customers' purchasing intention, should promote their brand equity through corporate social responsibility activities and offer a distinct service quality. Limitations in the progress of research were found and future indications to overcome these limitations are suggested as follows. First, survey responders had a limited understanding of social responsibilities; therefore, this concept needs to be explained to people first. Second, the research was done on people who live in Daejeon; thus, it is not representative of the entire country. The research has to be repeated with people in other cities. Third, there is a limitation in the study because the purposive selection method was used on Daejeon customers. In the future, a more precise selection of the population is needed. Fourth, Daejeon has unique geographical and size characteristics. Thus, customers in Seoul and other areas may display different characteristics and research on them may reveal different findings. Therefore, again, this study has to be repeated in other areas.

• 가족자원경영과 정책
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• 제25권3호
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• pp.17-30
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• 2021

본 연구는 2019년 현재 가족친화인증을 유지하고 있는 501개 기업(관)을 대상으로 인증 획득 후 가족친화경영 수준을 파악하고 기업(관)이 인지하는 기업성과와 사회적 성과를 분석하였다. 또한 인증 후 컨설팅, 가족친화 직장교육 등 사후지원이 인증기업(관)의 가족친화경영과 성과에 어떠한 영향을 미치는지에 대한 분석을 통해 가족친화경영의 활성화 방안을 도출하고자 하였다. 주요결과와 제언은 다음과 같다. 첫째, 인증기업(관)의 가족친화경영과 관련하여 가족친화 관련 제도의 규정화 운영수준은 높은 편이나, 성과지표 관리 측면은 가장 취약한 부분으로 나타났다. 이는 기업(관)의 실질적인 성과와 연동되는 가족친화경영 성과지표 산정과 측정 관리가 필요함을 시사한다. 둘째, 기업성과 중 기업(관) 홍보 및 이미지 개선과 조직신뢰향상, 사회적 성과 중 조직리더의 가족친화인식 향상과 성평등 직장문화 조성을 높게 인식하는 점을 정책적으로 홍보하고 기업(관)의 유인책으로 활용할 필요가 있다. 나아가 기존의 듀얼 아젠다 관점에서 확대된 제3의 아젠다인 사회적 성과로서 가족친화 사회환경 조성을 위한 기업(관)의 파급력을 강조할 것을 제안한다. 셋째, 전반적으로 인증 후 컨설팅이나 가족친화 직장교육의 경험이 있는 기업(관)이 없는 기업(관) 보다 가족친화경영 수준, 기업성과, 사회적 성과가 통계적으로 유의미하게 높은 것으로 나타났다. 이러한 결과는 가족친화경영이 지속적으로 활성화되고 기업 및 사회적 성과 달성을 위해서는 기업(관)의 장기적이고 체계적인 노력이 필요함을 시사한다.

• 대한소아치과학회지
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• 제48권3호
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• pp.245-254
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• 2021

이 연구의 목적은 소아 환자들의 측모방사선 사진을 대상으로 시판되는 3종의 자동 계측점 식별 프로그램의 정확성을 평가하고 소아치과 임상에서의 사용 가능성을 예측하는 것이다. 영구 중절치가 맹출한 만 7 - 12세 건강한 어린이 60명의 측모방사선 사진에 14개의 계측점을 표시하였다. 1명의 검사자가 3회 반복 측정한 결과의 평균을 기준점으로 정의하여 자동으로 식별된 계측점과의 거리 차이를 계측하였다. 3종의 자동 계측점 식별 프로그램은 평균 2.53 mm의 오차를 나타냈다. Orbitale과 Gonion을 제외한 12개의 계측점에서 3종의 프로그램 사이에 유의미한 차이는 없었으나, 검사자가 모든 계측점에서 3종의 프로그램보다 유의미하게 높은 정확도를 보였다. 이 연구를 통하여 사춘기 전 소아의 측모방사선 분석 시 자동 계측점 식별 프로그램이 검사자를 대체할 정도는 아니나 짧은 소요시간과 임상 허용 가능한 범위 이내의 정확도를 갖는 효과적인 진단 보조기구임을 알 수 있다.

• 생물정신의학
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• 제26권1호
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• pp.22-31
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• 2019

Objectives Previous studies have revealed inconsistent results on amygdala volume in adult bipolar disorder (BD) patients compared to healthy controls (HC). Since the amygdala encompasses multiple subregions, the subtle volume changes in each amygdala nucleus might have not been fully reflected in the measure of the total amygdala volume, causing discrepant results. Thus, we aimed to investigate volume changes in each amygdala subregion and their association with subtypes of BD, lithium use and clinical status of BD. Methods Fifty-five BD patients and 55 HC underwent T1-weighted structural magnetic resonance imaging. We analyzed volumes of the whole amygdala and each amygdala subregion, including the anterior amygdaloid area, cortico-amygdaloid transition area, basal, lateral, accessory basal, central, cortical, medial and paralaminar nuclei using the atlas in the FreeSurfer. The volume difference was analyzed using a one-way analysis of covariance with individual volumes as dependent variables, and age, sex, and total intracranial volume as covariates. Results The volumes of whole right amygdala and subregions including basal nucleus, accessory basal nucleus, anterior amygdaloid area, and cortico-amygdaloid transition area in the right amygdala of BD patients were significantly smaller for the HC group. No significant volume difference between bipolar I disorder and bipolar II disorder was found after the Bonferroni correction. The trend of larger volume in medial nucleus with lithium treatment was not significant after the Bonferroni correction. No significant correlation between illness duration and amygdala volume, and insignificant negative correlation were found between right central nucleus volume and depression severity. Conclusions Significant volume decrements of the whole amygdala, basal nucleus, accessory basal nucleus, anterior amygdaloid area, and cortico-amygdaloid transition area were found in the right hemisphere in adult BD patients, compared to HC group. We postulate that such volume changes are associated with altered functional activity and connectivity of amygdala nuclei in BD.

• Journal of the Korean Physical Society
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• 제73권10호
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• pp.1584-1588
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• 2018

During hyperthermia therapy, cancer cells are heated to a temperature in the range of $40{\sim}45^{\circ}C$ for a defined time period to damage these cells while keeping healthy tissues at safe temperatures. Prior to hyperthermia therapy, the amount of heat energy transferred to the cancer cells must be predicted. Among various non-invasive methods, the thermal prediction method using the specific absorption rate (SAR) is the most widely used method. The existing methods predict the thermal distribution by using a single constant for the mass density in one organ through assignment. However, because the SAR and the bio heat equation (BHE) vary with the mass density, the mass density of each organ must be accurately considered. In this study, the mass density distribution was calculated using the relationship between the Hounsfield unit and the mass density of tissues in preceding research. The SAR distribution was found using a quasi-static approximation to Maxwell's equation and was used to calculate the potential distribution and the energy distributions for capacitive RF heating. The thermal distribution during exposure to RF waves was determined by solving the BHE with consideration given to the considering contributions of heat conduction and external heating. Compared with reference data for the mass density, our results was within 1%. When the reconstructed temperature distribution was compared to the measured temperature distribution, the difference was within 3%. In this study, the density distribution and the thermal distribution were reconstructed for the agar phantom. Based on these data, we developed an algorithm that could be applied to patients.

• 한국시뮬레이션학회논문지
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• 제30권2호
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• pp.41-48
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• 2021

농촌 인구의 감소와 고령화가 지속되면서 농업 생상성 향상의 중요성이 높아지고 있는 가운데, 농작물 품질에 대한 조기 예측은 농업 생산성 및 수익성 향상에 중요한 역할을 할 수 있다. 최근 CNN 기반의 딥러닝 기술 및 전이 학습을 활용하여 농작물의 질병을 분류하거나 수확량을 예측하는 연구가 활발하게 진행되고 있지만, 수확 후 농작물의 품질을 식재단계에서 조기에 예측하는 연구는 찾아보기 힘들다. 본 연구에서는 건강 기능성 식품으로 주목받고 있는 새싹삼을 대상으로, 수확 후 새싹삼의 품질을 식재단계에서 조기에 예측하는 모델을 제안한다. 이를 위하여 묘삼의 이미지를 촬영한 후 수경재배를 통해 새싹삼을 재배하였고, 수확 후 새싹삼의 품질을 분류하여 실험 데이터를 수집하였다. 다수의 CNN 기반의 사전 학습된 모델을 활용하여 새싹삼 조기 품질 예측 모델을 구축하고, 수집된 데이터를 이용하여 각 모델의 학습 및 예측 성능을 비교 분석하였다. 분석 결과 모든 예측 모델에서 80% 이상의 예측 정확도를 보였으며, 특히 ResNet152V2 기반의 예측 모델에서 가장 높은 정확도를 보였다. 본 연구를 통해 인력에 의존하던 기존의 묘삼 선별 작업을 자동화하여 새싹삼의 품질을 높이고 생산량을 증대시켜 농가의 수익창출에 기여할 수 있을 것으로 기대된다.

• 한국임상수의학회지
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• 제38권3호
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• pp.135-142
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• 2021

The aim of this study was to evaluate the contrast effect if a saline flush following low-volume contrast medium bolus improves vascular and parenchymal enhancement using a saphenous vein in abdominal CT for small animals. Six clinically healthy beagle dogs underwent abdominal contrast-enhanced CT. They were divided into nine groups (each group, n = 6), according to the volume of contrast medium 1, 2, and 3 mL/kg, and volume of the saline solution 0, 5, and 10 mL. Dynamic CT scanning was performed at the hepatic hilum level. The maximum contrast enhancement, time to maximum enhancement, and time to equilibrium phase were calculated from the time attenuation curves. Mean attenuation values for all groups were measured in the aorta, portal vein, and liver. After contrast enhancement, grading of image quality regarding surrounding artifacts and evaluation of the hepatic hilum structures was performed. For comparison of the effect of the contrast material and saline solution doses, differences in mean attenuation values between the contrast medium 2 mL/kg without saline flush group and the remaining groups, and between contrast medium 3 mL/kg without saline flush group and the remaining groups, were analyzed for statistical significance. There were no significant differences between with and without saline flushing at the same contrast medium dose groups. There were no significant differences in peak values between the 3 mL/kg dose of contrast medium alone and the 2 mL/kg dose of contrast medium with saline solution flush. However, there was a significant difference in peak values between the 3 mL/kg dose of the contrast medium without the saline flush group and the 2 mL/kg dose of the contrast medium alone group. Grades of the artifacts were not significantly different in the saline flush regardless of the dose of the contrast medium. Using 2 mL/kg of contrast medium with saline solution flush resulted in similar liver parenchyma attenuation, compared with using 3 mL/kg of contrast medium without saline solution flush. In CT evaluation of hepatic parenchymal diseases, using 2 mL/kg of contrast medium with saline solution flush may yield decreased risk of contrast nephropathy and cost-saving.