• Journal of Veterinary Clinics
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• v.24 no.4
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• pp.593-596
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• 2007

The purpose of this study is to investigate normal hepatobiliary functions in healthy miniature pigs. $^{99m}Tc-DISIDA$ hepatobiliary scintigraphy(HBS) was used for it. Five mCi dose of $^{99m}Tc-DISIDA$ was injected intravenously into 3 healthy adult miniature pigs, and dynamic images were obtained during 1 hour. $^{99m}Tc-DISIDA$ HBS in a miniature pig was evaluated for 6 variables. A cardiac washout occurred within 1 min in all miniature pigs and radioactivities in the gallbladder were not detected in two miniature pigs. Thus, the initial radioactivity and Tmax of the gallbladder were non-available to identify. Mean Tmax of liver was $8.67{\pm}2.08$ min and initial small intestinal radioactivity was seen at $9.67{\pm}2.52$ min after $^{99m}Tc-DISIDA$ injection. Mean hepatic washout time was not detected in 60 min dynamic images. Therefore, $^{99m}Tc-DISIDA$ HBS is the effective diagnostic method to evaluate the function of hepatocyte and bile flow rate. However, it was not a proper method to evaluate the function of gallbladder, which indicates that an additional study is needed to further specify the reasons for the absence of radioactivities in gallbladder of two miniature pigs.

• The Journal of Korean Physical Therapy
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• v.27 no.5
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• pp.299-303
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• 2015

Purpose: The objective of this study was to examine the changes in muscle activity on the anterior deltoid muscle depending on the stretch rate of kinesio tape when applying kinesio tape in healthy adult subjects. Methods: This study was a single-blind randomized controlled trial, including 22 healthy participants (male 15, female 7) with no pathology or past history of shoulder who participated voluntarily. Participants applied a different stretch rate of the kinesio tape, and the functional activity was tested. The stretch rate of kinesio tape was 0%, 10%, and 20%. Subjects lifted a weight (5% of their body weight) to their shoulder height. Subjects lifted a weight up to an angle of 90 degrees in the sagittal plane, and muscle activities (biceps brachii, anterior deltoid, middle deltoid, upper trapezius) were assessed using EMG (electromyography). Analysis of muscle activity was divided into two parts (lift weight and keep holding). The EMG activity of each muscle was normalized to the value of reference voluntary contraction (%RVC) and explored using repeated ANOVA. Results: There were no significant differences in muscle activity depending on the ratio of tape stretch when lifting a weight (p>0.05). There were no significant differences in muscle activity depending on the ratio of tape stretch when holding a weight (p>0.05). Conclusion: According to the results of this study, in the case of applying kinesio taping therapy for healthy people, it was found that the stretch rate of the tape does not have an effect on muscle activity.

• Journal of Nutrition and Health
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• v.36 no.1
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• pp.49-63
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• 2003

The purpose of this study was to obtain the nutritional values and objective data of uncooked powdered food (UPF) in korea. We interviewed 27 healthy female subjects aged over 25 years living in the lksan area. We just replaced common breakfast and dinner of the subjects with UPF. Their dietary intake status was evaluated by 24-hour recall method. Their body compositions were measured using body fat analyzer. Also we conducted hematological and clinical analysis of blood. The intake of energy, lipid and protein has decreased as people started to take UPF, but the intake of vitamins and minerals has increased. The quality of meals has improved after taking UPF. Due to the energy loss by taking UPF, weight and body fat gradually lessened. Among the lost weight the percentage of the body fat was high and we judged that the process of losing weight was successful. It is hard to predict whether weight loss will occur to people who are already in shape or not, but if overweight and obesity people regularly take UPF instead of other food products, we assume that UPF will help lessening body fat. The most positive change among biochemical changes by taking UPF was decreasing of serum lipid contents. The concentrations of total cholesterol and LDL-cholesterol gradually decreased and decreased intently after 12weeks. Serum HDL-cholesterol gradually increased and serum triglyceride showed gradual decrement. When healthy adult women replaced two of three meals with UPF for 3months, we were able to see some useful changes like decrement of body fat and serum lipid control and during this 3month period, no significant nutritional problems occurred. Complete judgement on UPF may be difficult with these conclusions but if people take a nomal meal once and replenish iron from taking UPF twice a day, we assume that replacing UPF with regular meal not be a problem in nutritional status. If other experiments on the effects of UPF proceed, we believe that those experiments will be very helpful in judging the nutritional value of UPF. (Korean J Nutrition 36(1) : 49-63, 2003)

• Korean Journal of Community Nutrition
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• v.25 no.1
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• pp.61-70
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• 2020

Objectives: This study examined the association of the total diet quality with the incidence risk of metabolic syndrome constituents and metabolic syndrome among Korean adults. Methods: Based on a community-based cohort of the Korean Genome and Epidemiology Study (KoGES) from 2001 to 2014, data from a total of 5,549 subjects (2,805 men & 2,744 women) aged 40~69 years at the baseline with a total follow-up period of 38,166 person-years were analyzed. The criteria of the National Cholesterol Education Program Adult Treatment Panel was employed to define metabolic syndrome. The total diet quality was estimated using the Korean Healthy Eating Index (KHEI). Hazard ratios (HR) and 95% confidence intervals (CI) for risk of metabolic syndrome constituents and metabolic syndrome in relation to KHEI quintile groups was calculated by multivariate Cox proportional hazards regression model. Results: After adjusting for age, energy intake, income, education, physical activity, smoking, and drinking, the incidence of abdominal obesity and high blood pressure was significantly lower, by approximately 29.7% (P < 0.01) and 25.2% (P < 0.01), respectively, in the fifth KHEI quintile compared to the first quintile in men. A significant decreasing trend of the metabolic syndrome incidence was observed across the improving levels of KHEI (HRq5vs.q1: 0.775, 95% CIq5vs.q1: 0.619~0.971, P for trend < 0.01). In women, the incidence of abdominal obesity and metabolic syndrome was significantly lower, by approximately 29.8% (P < 0.01) and 22.5% (P < 0.05), respectively, in the fifth KHEI quintile compared to the first quintile adjusting for multiple covariates. On the other hand, the linear trend of metabolic syndrome risk across the KHEI levels did not reach the significance level. Conclusions: A better diet quality can prevent future metabolic syndrome and its certain risk factors among Korean men and women.

• Nutrition Research and Practice
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• v.10 no.2
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• pp.182-187
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• 2016

BACKGROUND/OBJECTIVES: Supplementation with n-3 polyunsaturated fatty acids (PUFAs) has been shown to generally decrease levels of innate immune markers and inflammatory cytokines, but the specific associations between blood levels of PUFAs and those of innate immune markers have not been investigated. Thus, the present study was conducted to test the hypothesis that innate immune markers as well as cytokines are negatively associated with n-3 PUFAs but positively associated with n-6 PUFAs in healthy adults. MATERIALS/METHODS: One hundred sixty-five healthy Korean adults aged 25-70 years old were included in this cross-sectional study. RESULTS: Serum levels of n-3 PUFAs, such as 18:3n3, 20:5n3, 22:5n3, and 22:6n3 were negatively correlated with eosinophil and basophil counts and $TNF-{\alpha}$, $IFN-{\gamma}$, IL-4, and IL-10 levels. Multivariate analysis also showed that serum levels of n-3 PUFAs were negatively associated with monocyte, eosinophil, and basophil counts and $TNF-{\alpha}$, $IFN-{\gamma}$, IL-4, and IL-12 levels. Additionally, the ratio of 20:4n6 to 20:5n3 was positively correlated with eosinophil counts and associated with $TNF-{\alpha}$, $IFN-{\gamma}$, and IL-4 levels. However, NK cell activity was not associated with serum fatty acid composition. CONCLUSIONS: Innate immune markers such as eosinophil, monocyte, and basophil counts were inversely associated with serum levels of n-3 PUFAs, but were positively associated with the 20:4n6/20:5n3 ratio in this population.

• The Korean Journal of Pain
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• v.31 no.1
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• pp.16-26
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• 2018

Background: The aim of this study was to investigate the association between neuroticism, pain catastrophizing, and experimentally induced pain threshold and pain tolerance in a healthy adult sample from two regions of the country of Croatia: the island of Korcula and city of Split. Methods: A total of 1,322 participants were enrolled from the Island of Korcula (n = 824) and the city of Split (n = 498). Participants completed a self-reported personality measure Eysenck Personality Questionnaire (EPQ) and pain catastrophizing questionnaire Pain Catastrophizing Scale (PCS), followed by a mechanical pain pressure threshold and tolerance test. We have explored the mediating role of catastrophizing in the relationship between neuroticism and pain intensity. Results: The results showed that pain catastrophizing partially mediated the relationship between neuroticism and pain intensity, suggesting the importance of pain catastrophizing in increasing vulnerability to pain. The results also indicated gender-related differences, marked by the higher pain threshold and tolerance in men. Conclusions: This study adds to the understanding of the complex interplay between personality and pain, by providing a better understanding of such mechanisms in healthy adults.

• Journal of the Korean Society of Physical Medicine
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• v.15 no.2
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• pp.1-9
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• 2020

PURPOSE: This study examined the effects of different external loads on the muscle activities around the hip during prone hip extension with knee flexion (PHEKF) exercise in healthy young men. METHODS: Sixteen healthy adult males participated in the study. A pressure biofeedback unit was used to provide feedback to the participants during the abdominal drawing-in maneuver (ADIM) with PHEKF. Sandbags (0 kg, 1 kg, 2 kg, and 3 kg) were used to provide external resistance. The quadriceps was contracted to maintain knee flexion 90° against resistance. Each resistance condition using a sandbag weight was given in random order. Surface electromyography (sEMG) was used to measure the electrical activity of the gluteus maximus, biceps femoris, and erector spinae during PHEKF. RESULTS: The muscle activity of the gluteus maximus was highest with the 3 kg resistance and lowest with 0 kg (F = 128.46, P = .00). The muscle activities of the biceps femoris and erector spinae were highest with 0 kg and lowest with 3 kg (F = 29.49, P = .00). The muscle activity rate of the gluteus maximus/biceps femoris was highest with 3 kg and lowest with 0 kg (F = 37.49, P = .00). CONCLUSION: The activity of the gluteus maximus was increased using a higher external weight load during PHEKF, while the activity of the biceps femoris decreased. These findings suggest that an external weight is needed during hip extensor exercise to strengthen the gluteus maximus and inhibit the biceps femoris.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.7043-7052
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• 2015

This study divides subjects into people with metabolically healthy obesity and those with metabolically unhealthy obesity to identify the physical activities and nutrients influencing adults with obesity. Participants in the sixth Korea National Health and Nutrition Examination Survey conducted from January through December 2013 were selected as the subjects, and an analysis of complex survey samples was conducted with them. It was found that the number of days of a flexibility exercise (Odds ratio (OR)=1.18, 95% confidence interval (95% CI)=1.01-1.38), water intake (OR=1.04, 95% CI=1.01-1.06) and protein intake (OR=1.07, 95% CI=1.02-1.13) for one week were higher in people with metabolically healthy obesity than in those with metabolically unhealthy obesity, while their fat intake (OR=0.99, 95% CI=0.98-1.00)and carbohydrate intake (OR=0.98, 95% CI=0.97-0.99) were lower. Based on the results of this study, it was found that nursing intervention for obesity would need an approach according to the metabolic condition of obesity.

• Journal of Veterinary Clinics
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• v.24 no.2
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• pp.160-163
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• 2007

Patients often present with spontaneous bleeding, or a bleeding disorder may be discovered when an otherwise healthy dog develops marked bleeding during or after surgery. In this study, we were aimed to elucidate whether the cesarean section in dogs has influence on the coagulation profiles. And we gained the normal data on a panel of screening laboratory tests which allow accurate characterization of a hemostatic defects in dogs. Of the 20 healthy adult dogs, buccal mucosa bleeding time (BMBT) was $83.0{\pm}10.5$ seconds, platelet count was $24.0{\pm}3.5{\times}10^4/{\mu}l$, activated partial thromboplastin time (APTT) was $8.8{\pm}2.0$ seconds, the concentration of fibrinogen was $288.5{\pm}77.9mg/dl$, and the concentration of fibrin degradation products (D-dimer) was <250.0 ng/ml. Coagulation profiles before and after cesarean section of 13 cesarean sectioned dogs were in the normal range and there were no statistical differences in coagulation profiles between normal dogs and cesarean sectioned dogs (p>0.05). The results suggested that labor and cesarean section in healthy dogs did not alter coagulation profiles.

• PNF and Movement
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• v.13 no.3
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• pp.119-125
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• 2015

Purpose: The current study seeks to examine the effects of stabilizing reversal(SR) and rhythmic stabilization(RS) in proprioceptive neuromuscular facilitation (PNF) techniques on static balance in normal female adults. Methods: Subjects included 20 healthy women in their 20s. They were randomly divided into SR and RS groups. To assess static balance before and after PNF intervention, the good balance system was used to measure the interior and exterior center of pressure (COP) movement distance, front and rear COP movement distance before and after the intervention, and velocity moment. Results: Interior and exterior COP movement distance, front and rear COP movement distance, and velocity moment decreased in the SR group, but no statistically significant differences were observed. In the RS group, the interior and exterior COP movement distance declined without any significant difference, while the front and rear COP movement distance and velocity moment significantly decreased. The interior and exterior COP movement distance, front and rear COP movement distance, and velocity moment declined more in the RS group than in the SR group. Conclusion: The findings of the current study indicate that the RS technique is more effective than the SR technique for improving the balance ability of healthy female adults. The results of this study can thus be utilized in the selection of effective interventions for improving the balance ability of healthy female adults.