• Title/Summary/Keyword: Health state analysis

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Current Evidence on the Association between rs3757318 of C6orf97 and Breast Cancer Risk: a Meta-Analysis

  • Hong, Yuan;Chen, Xue-Qin;Li, Jiao-Yuan;Liu, Cheng;Shen, Na;Zhu, Bei-Bei;Gong, Jing;Chen, Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8051-8055
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    • 2014
  • Background: A common genetic variant rs3757318, located in intron of C6orf97, was firstly identified to be associated with breast cancer (BC) risk by a genome-wide association (GWA) study. However, subsequent validation studies with different ethnicities have yielded conflicting results. Materials and Methods: We performed a meta-analysis to synthesize all available data for evaluating the precise effect of this variant on BC susceptibility. Results: A total of 8 articles containing 11 studies with 62,891 cases and 65,635 controls were included in this meta-analysis. When compared to the G allele, the rs3757318-A allele was significantly associated with BC risk with the pooled OR of 1.21 (95% CI=1.15 - 1.29, P<0.001) but with obvious between-study heterogeneity (P=0.040). Stratified analysis suggested that diversity of ethnicity along with control source may explain part of the heterogeneity. Similarly, significant associations were also identified in heterozygote, homozygote, dominant and recessive genetic models. Sensitivity and publication bias analyses indicated robust stability of our results. Conclusions: Our present meta-analysis demonstrated that the variant rs3757318 is associated with increased BC risk. Nevertheless, further studies are needed to clarify the underlying biological mechanisms.

Online automatic structural health assessment of the Shanghai Tower

  • Zhang, Qilin;Tang, Xiaoxiang;Wu, Jie;Yang, Bin
    • Smart Structures and Systems
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    • v.24 no.3
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    • pp.319-332
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    • 2019
  • Structural health monitoring (SHM) is of great importance to super high-rise buildings. The Shanghai Tower is currently the tallest building in China, and a complete SHM system was simultaneously constructed at the beginning of the construction of the tower. Due to the variety of sensor types and the large number of measurement points in the SHM system, an online automatic structural health assessment method with few computations and no manual intervention is needed. This paper introduces a structural health assessment method for the Shanghai Tower that uses the coefficients of an autoregressive (AR) time series model as structural state indicators. An analysis of collected data indicates that the coefficients of the AR model are affected by environmental factors, and the principal component analysis method is used to remove the influence of environmental factors. Finally, the control chart method is used to track the changes in structural state indicators, and a plan for online automatic structure health state evaluation is proposed. This method is applied to long-term acceleration and inclination data from the Shanghai Tower and successfully identifies the changes in the structural state. Overall, the structural state indicators of the Shanghai Tower are stable, and the structure is in a healthy state.

Melanoma Incidence Mortality Rates and Clinico-Pathological Types in the Siberian Area of the Russian Federation

  • Gyrylova, Svetlana Nikolaevna;Aksenenko, Mariya Borisovna;Gavrilyuk, Dmitriy Vladimirovich;Palkina, Nadezda Vladimirovna;Dyhno, Yuriy Alexandrovich;Ruksha, Tatiana Gennadievna;Artyukhov, Ivan Pavlovich
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2201-2204
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    • 2014
  • Russian rates for melanoma incidence and mortality are relatively low as compared to some other white populations but the tumor is of increasing importance. In this paper, data are based on a retrospective descriptive analysis of melanoma epidemiology and clinicopathological characteristics in Krasnoyarsk Territory belonging to the Siberian Federal District of the Russian Federation. The age-adjusted incidence and mortality rates for the period 1996-2009 were determined with subsequent retrospective analysis of clinicopathological data of 103 primary melanoma cases. Our results showed that incidence and mortality rates in the region under consideration match the Russian national trends and correspond to epidemiological data of the countries of Eastern Europe. Stratification of melanoma cases by age, sex, clinicopathological state and localization revealed a prevalence of lesions on the trunk and lower extremities. Most melanomas diagnosed were of superficial spreading type and the third Clark's level of tumor invasion and stage II according to AJCC. In spite of comparatively low rates of incidence and mortality the trend to increase of melanoma cases in the region under consideration obviously calls for more attention and further investigation.

A Study of Factors influencing Health Promotion Lifestyle in Women College Students (비건강 관련 학과 여대생의 건강증진생활양식과 영향요인)

  • Yoo, Kyung-Hee;Cho, Kyung-Mi
    • The Journal of Korean Academic Society of Nursing Education
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    • v.18 no.2
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    • pp.343-352
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    • 2012
  • Purpose: The purpose of this study was to identify the factors influencing Health Promotion Lifestyle Profile of women college students. Methods: The sample consisted of 248 women college students in P city. Self report questionnaires were used to measure the variables. In data analysis, SPSSWIN 20.0 program was utilized for descriptive statistics, Pearson's correlation coefficients, and regression analysis. Results: The mean score for Health Promotion Lifestyle Profile was 2.27. In the the highest subcategories, the highest degree of performance was interpersonal relationships and the lowest degree was health responsibility. Health Promotion Lifestyle Profile was significantly different according to religion (F=3.48, p=.017), economic state(F=3.01,p=.031), perceived health state(F=8.07, p<.001), exercise frequency (F=16.02, p<.001), and self-rated knowledge about health (F=21.08, p<.001). In regression of analysis, perceived health state, exercise frequency, and self-rated knowledge about health were significant predictors explaining 30.5%. Conclusion: This study suggests that perceived health state, exercise frequency, and self-rated knowledge about health are significantly influencing factors in Health Promotion Lifestyle Profile in women college students. Therefore, the strategies of nursing intervention which improve these variables must be developed for women college students.

A Study on the Stress and Adjustment to College Life among Nursing Students (간호대학생의 대학생활스트레스와 대학생활적응)

  • Yoo, Kyung Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.24 no.3
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    • pp.269-278
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    • 2018
  • Purpose: This study was conducted to investigate the correlation between stress and adjustment to college life among nursing students. Methods: The sample consisted of 183 university students in C & S cities. Self-report questionnaires were used to measure the variables. In data analysis, SPSSWIN 23.0 program was utilized for descriptive statistics, Pearson's correlation coefficients, and regression analysis. Results: The mean scores of stress and adjustment to college life were 2.55 and 3.24. Stress was significantly different according to grade (F=7.30, p<.001), economic state (F=14.39, p<.001), perceived health state (F=6.66, p<.001). In regression analysis, stress for college life, perceived health state, and college life satisfaction were significant predictors of adjustment to college life explaining 68%. Conclusion: This study suggests that perceived health state was a significant factor on adjustment to college life among nursing students. Therefore, the strategies of nursing intervention which improve perceived health state must be developed for college students.

The relationship of oral state and health condition among elderly people (노인의 구강건강상태와 전신건강의 상태)

  • Won, Young-Soon;Jin, Ki-Nam
    • Journal of Korean society of Dental Hygiene
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    • v.3 no.2
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    • pp.157-168
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    • 2003
  • The purpose of this study was to examine the relationship of oral state and health condition among elderly people. The subjects in this study were 220 senior citizens who were randomly selected from among dwellers in Eunpyeong-gu and Jongno-gu, Seoul. A survey was conducted by one-on-one interview to find out their oral state and health condition. The collected data were analyzed with SPSS 10.0 program, and variance analysis, correlation analysis and regression procedure were employed. The findings of this study were as follows: First, Regarding subjective oral health state, 52.3 percent of the elderly people, more than the half, considered their mouth to be in good health. The number of their mean remaining permanent teeth was 14.85, which was one of the indexes to indicate their objective oral state. Second, Concerning their abnormal oral health experience, 75 percent didn't feel that their masticatory force was good enough, and 55.9 percent felt pain in their teeth, 70.0 percent suffered from mouth dryness. Those fact showed that a lot of the elderly people felt there was something wrong with their oral cavity, and the unhealthy oral state made it difficult for them to eat food, as their masticatory force weakened and they couldn't get a good taste for food. Third, Those who viewed their oral cavity as healthy thought that they were in good shape, and there was a significant correlational relationship between their subjective oral and overall physical health states. Their own perception of oral state made a difference to their subjective health status, and the subjective oral health was significantly related to ADL as well, which implied that their ADL was different according to the way they looked at their own oral health status.

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Factors Affecting Mental Health among College Students - Sassang Constitution and Ego State centered Approach- (대학생의 정신건강에 영향을 주는 요인 - 사상체질과 자아상태를 중심으로 -)

  • Kim, Myoung-Hee
    • Journal of Korean Public Health Nursing
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    • v.27 no.3
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    • pp.564-577
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    • 2013
  • Purpose: The purpose of this study was to address differences between mental health according to sasang constitution and ego state among college students. Methods: Data for this cross-sectional study were collected by administration of questionnaires eliciting Woo's ego state scale, QSCC II for the sasang constitution classification, and SCL-90-R for mental health to 393 college students. Analysis was performed using IBM SPSS (version 19.0). Results: The Free Child ego and Adapted Child ego differed significantly among sasang types. The ego-gram pattern of So-eum type exhibited the N pattern (Nurturing Parent (NP)>Adapted Child (AC)>Adult (A)>Free Child (FC)>Critical Parent (CP), AC-high type), however, the ego-gram pattern of other constitution types showed the M pattern (NP>FC>A>AC>CP). No statistically significant differences in mental health were observed among sasang types, however, among ego states, AC and CP showed negative correlation with mental health status. Between So-eum type and So-yang type, AC was the factor predicting mental health. Between Tae-eum type and undefined type, AC and CP were factors predicting mental health. Conclusion: These findings suggest that sasang constitution could be an important factor in understanding the ego state and mental health status. We conclude that sasang constitution should be considered in interpretation of mental health status presentation in clients.

Factors Influencing Health Promoting Behavior among Hospital Registered Nurses - Mood States, Resourcefulness, and Health Perception - (일부 병원 간호사의 기분상태, 자원동원성 및 건강지각이 건강증진행위에 미치는 영향)

  • Yeun, Eun-Ja;Kim, Hee-Jeong;Jeon, Mi-Soon
    • Journal of Korean Academy of Nursing Administration
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    • v.17 no.2
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    • pp.198-208
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    • 2011
  • Purpose: This study was done to examine the effects of mood state, resourcefulness, and health perception on health promoting behavior of hospital nurses. Methods: Convenience sampling was conducted for nurses working at three University hospital and 336 nurses were selected. Data were analyzed using SPSS 18.0. Results: The results of the analysis showed that the score for nurses' mood state was $41.76{\pm}18.90$; for resourcefulness, $11.30{\pm}20.63$; for health perception, $3.32{\pm}.77$, and for health promoting behavior, $111.55{\pm}17.76$. Mood state, resourcefulness, and health perception were significantly correlated with health promoting behavior. The overall explanatory power of the effects of nurses' mood state, resourcefulness, and health perception on health promoting behavior was 27.8%. Conclusion: Study results indicate that better mood state, higher resourcefulness, and higher health perception result in more health promoting behavior.

Influence of Age-Identity on Existential Identity and Psychological Well-Being of the Elderly (노인의 연령정체감이 실존적 정체감과 심리적 안녕감에 미치는 영향)

  • Lee, Shin Sook
    • Human Ecology Research
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    • v.52 no.2
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    • pp.151-164
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    • 2014
  • This study was conducted to explore the relationships between the elderly's existential identity and psychological well-being in accordance with the elderly's age-identity so as to improve the quality of life in the elderly with prolonged lives. The data were collected from respondents who were more than 60 years in age who live in city Suncheon. The statistics used for the data analysis were reliability, frequency, percentage, mean, standard deviation, one way analysis of variance, and multiple regression. The results of this study were as follows: (1) A majority of the elderly (49.8%) acknowledged psychological age as actual age. (2) The degrees of the elderly's existential identity was 54.90, while the degree of the elderly's psychological well-being was 33.07. (3) The elderly's existential identity level was significantly affected by economic state, spouse, age-identity, monthly living expenses, household, religion, career, age, and health state. Further, the elderly's psychological well-being level was significantly affected by existential identity, economic state, spouse, health state, age-identity, monthly living expenses, household, education, career, and age. (4) The variables that affect the elderly's existential identity were age-identity, economic state, health state, religion, monthly living expenses, and career, indicating an explanatory power of 38%. Moreover the variables that affect the elderly's psychological well-being were existential identity, age-identity, economic state, health state, and monthly living expenses, explaining approximately 55% of the total variance.

Relationship between Quality of Life and validated for constituent concepts validity using OHIP (OHIP의 구성개념 타당성 검증 및 삶의 질과의 관련성)

  • Kim, Hye-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.7 no.4
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    • pp.441-453
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    • 2007
  • This study was conducted among 831 industrial workers in Gumi City in Gyung-Sang-Buk Do for the purpose of acquiring knowledge to improve quality of life though industrial workers' oral health promotion. Oral examination and questionnaire surveying were used to evaluate workers' oral health state and subjective health state and analyze their effect on quality of life. At the same time, the scales used in measuring the subjects' health state and quality of life-OHIP and WHOQOL-BREF-were validated for their constituent concepts and their relations were analyzed through structural modeling. The analysis results can be summarized as follows; The constituent concepts of OHIP and QOL factor structural models were validated since they were all in the range of appropriateness, as shown in the result of analysis using Indices of Fit-GFI, CFL, TLI and RMSEA. The result of analysis of constituent concepts to identitify the relations between OHIP and QOL confirmed that OHIP influences QOL.

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