• 대한예방한의학회지
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• 제21권2호
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• pp.95-103
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• 2017

Objectives : The aim of this study is to analyze the news contents of Korean style medicinal tea and investigate how it is portrayed in the consumer market. Methods : Total of 355 articles are selected by inputting "Korean style medicinal tea" and analyzed; 108 articles for 2013, 107 articles for 2014, 140 articles for 2015. Results : 175 different tea were found from Jan. $1^{st}$ 2013 to Dec. $31^{st}$ 2015, with ginger tea the most frequently covered for 68 times. Among 175 tea, 117 had one ingredient and 58 had more than one ingredient. The most frequently covered category was "Disease and Health Promotion" followed by "Commercial Ads", "Korean style medicinal tea Culture", and others. From 355 articles, 188 provided the information on the efficacy of Korean style medicinal tea, 88 presented the pharmacological activity, 84 addressed the recipe, 80 explained the taste, and 31 included ancient literature. The most frequently covered tea were ginger tea, omija tea, gugija tea, jujube tea, mogwa tea. Autumn and winter had 109 articles, spring had 89, and summer had 86. Conclusions : This study showed the potential of Korean style medicinal tea as a successful future content. Most of the articles about Korean style medicinal tea contained information about the efficacy but practical information such as the recipe and drinking method were not addressed much. Therefore, future study is needed to investigate additional information about Korean style medicinal tea.

• Clinical and Experimental Reproductive Medicine
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• 제40권2호
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• pp.67-75
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• 2013

Objective: To investigate the effect of peroxisome proliferator activated receptor ${\gamma}$(PPAR${\gamma}$) agonist on the cell proliferation properties and expression of human telomerase reverse transcriptase (hTERT) and aromatase in cultured endometrial stromal cell (ESC) from patients with endometriosis. Methods: Human endometrial tissues were obtained from women with endometriosis and healthy women (controls) using endometrial biopsy. Isolated ESCs were cultured and the cell proliferation was measured by 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide assay and expression of hTERT, aromatase, and cyclooxygenase (COX)-2 by western blotting according to the addition of rosiglitazone (PPAR${\gamma}$ agonist). Results: We demonstrate that the cultured ESCs of endometriosis showed hTERT protein overexpression and increased cellular proliferation, which was inhibited by rosiglitazone, in a dose-dependent manner. At the same time, PPAR${\gamma}$ agonist also inhibited aromatase and COX-2 expression, resulting in decreased prostaglandin $E_2$ production in the ESCs of endometriosis. Conclusion: This study suggests that PPAR${\gamma}$ agonist plays an inhibitory role in the proliferative properties of eutopic endometrium with endometriosis by down-regulation of hTERT and COX-2 expression; this could be a new treatment target for endometriosis.

• 대한한방체열의학회지
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• 제3권1호
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• pp.27-35
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• 2004

Today, everybody lives in the stress. So 50% to 80% or 60% to 80% of the modern diseases are estimated what is caused by the stress. And one of the most important point of the stress is a too serious and continuos tension state. Therefore the best way to promotion, persistence, prevention and treatment of the modern man's health will be the relaxion from the tension state. The relax therapy as known as am effective method to the disease which as concerned with stress. that can be adapted to the treatment of anxiety-related diseases, insomnia, hypertension, tension headache, migraine, asthma, preparation of delivery, G-I disorders and menstrual disorders. Until now we guess the change of a relaxed state by the observation to the change of autonomic nervous system(ANS) and EEG. From the point of the ANS, sympathetic nervous system progresses slowly but parasympathetic nervous system increases the activity. In the EEG, both the alpha-wave concerned with the deep physical relaxed state and emotional stability and the theta-wave appeared in the state of meditation are increased. Current studies show that among the biochemical changes, especially serotinin like body hormone is increased by the feeling of the stability or the happiness. So, to see the change of the relaxed state in the image of the D.I.T.I., we used the deviational differences between the pre-relaxed state and the post-relaxed state of 70 people. As a result, the portional deviation of the face is decreased in the image of the D.I.T.I. So it can be thaught that we can determine the changes of the relaxed state by the D.I.T.I.

• 문화기술의 융합
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• 제4권1호
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• pp.315-323
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• 2018

당뇨 환자의 급격한 증가는 한국의 주요 건강문제중 하나이다. 당뇨 예방 또는 치료용 식품개발에 대한 노력의 일환으로 본 연구에서는 고지방식이급여로 유도한 제2형 당뇨동물모델에서 커큐민의 항당뇨효능을 연구하였다. C57BL/6 마우스를 정상식이, 고지방식이, 그리고 고지방식이에 0.02% 커큐민을 급여한 군으로 나누고 각 식이를 총 16주간 급여하였다. 그 결과, 커큐민 급여군이 고지방식이급여군에 비해 체중 증가량, 혈당, 혈중 인슐린, 총콜레스테롤, LDL-콜레스테롤 농도가 유의적으로 감소하였고 반면에 HDL-콜레스테롤 수준은 증가하였다. 또한 커큐민의 급여는 인슐린 신호전달체계를 활성화시켰다. 이러한 결과는 커큐민이 인슐린 저항성을 일부 극복시킴으로써 비만과 연관된 제2형 당뇨병을 개선시킬 수 있음을 제시한다.

• Nutrition Research and Practice
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• 제12권2호
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• pp.166-172
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• 2018

BACKGROUND/OBJECTIVES: Obesity and alcohol drinking are associated with metabolic syndrome. However, few studies show the relationship between alcohol drinking and metabolic syndrome according to varying degrees of obesity. This study aimed to determine the association between alcohol drinking and metabolic syndrome in obese and non-obese Korean male adults. SUBJECTS/METHODS: This cross-sectional study included 5,867 males aged ${\geq}20$ years who were examined at the Soonchunhyang University health promotion center during June 2008-December 2010. The subjects were divided into non-obese (body mass index [BMI] < $25kg/m^2$) and obese (BMI ${\geq}25kg/m^2$) groups and further divided according to weekly alcohol consumption into nondrinking (0 drinks/week), moderate drinking (${\leq}14$ drinks/week), and heavy drinking (> 14 drinks/week) groups. The subjects were also categorized into binge drinking and non-binge drinking groups. To obtain odds ratios (ORs) for metabolic syndrome, binary logistic regression analysis was performed. RESULTS: The overall metabolic syndrome prevalence was 27.3% (12.8%, non-obese group; 50.4%, obese group). After adjusting for age, physical activity, and smoking, in the non-obese group, the OR for heavy drinking with binge drinking (reference: nondrinking) was 1.56 (95% confidence interval [CI] = 1.12-2.18), with a significant increase in metabolic syndrome prevalence. In the obese group, the OR for heavy drinking with binge drinking was 1.42 (95% CI = 1.07-1.88), showing a significant increase in metabolic syndrome prevalence (P < 0.05). CONCLUSIONS: In both non-obese and obese Korean males, heavy drinking with binge drinking was associated with increased risk of metabolic syndrome. Thus, both non-obese and obese males should restrict their alcohol intake and not indulge in binge drinking.

• 기본간호학회지
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• 제12권1호
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• pp.21-29
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• 2005

Purpose: The purpose of this study was to identify the frequency with which nursing interventions according to domains and classes, and core nursing interventions of the Nursing Intervention Classification (NIC) were performed by nurses on orthopedic surgery nursing units. Method: For this purpose, the third edition of NIC was used. Of the 486 nursing interventions, 424 were selected at 75% consent by experts. Data were collected from June, 2003 to July, 2003 5 hospitals and 69 nurses(return rate : 95.8%) in Gwang-ju and Chonnam region. 5 point Likert scale describing frequency was used. Results: The most frequently performed domain was 'physiological : basic'($2.97{\pm}.60$), followed by 'health system'($2.65{\pm}.65$) and 'physiological : complex'($2.55{\pm}.46$). The most frequently performed class was 'activity and exercise management'($3.82{\pm}.89$), followed by 'immobility management'($3.64{\pm}.62$), 'skin/wound management'($3.41 {\pm}.60$), 'physical comfort promotion'($3.23{\pm}.68$) and 'thermoregulation'($3.01{\pm}.91$). The most frequently performed nursing intervention was 'medication administration' ($4.96{\pm}.21$), followed by 'medication administration : intravenous'($4.93{\pm}.31$), 'analgesic administration'($4.91{\pm}.51$), 'pain management'($4.87{\pm}.34$) and 'medication administration : intramuscular'($4.78{\pm}.68$). Conclusion: In conclusion, the third edition of NIC was found to be a general and comprehensive classification system for application on orthopedic surgery nursing units. These findings will help in building of a standardized language for orthopedic surgery nursing units and enhance the quality of nursing care.

• 스트레스연구
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• 제26권4호
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• pp.259-267
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• 2018

본 연구는 독거노인의 인지기능과 삶의 만족도에 영향을 미치는 위험요인을 탐색하고자 하였다. 전국표본추출로 실시된 2014년도 노인실태조사 원시자료 중에서 만 65세 이상인 독거노인 2,449명의 자료를 분석하였다. 인지기능의 위험요인은 고령과 사별경험, 무학력, 운동 안함, 낮은 사회문화 활동만족도로 확인되었다. 삶의 만족도 위험요인은 이혼/미혼/별거경험, 무학력, 미취업, 부정적 건강평가와 우울진단, 운동 안함, 정서적 학대, 경제적 학대, 재정적 방임 경험과 낮은 인지기능 수준으로 확인되었다. 이는 고령의 사별한 독거노인 대상의 적극적인 인지기능 검사 및 강화 프로그램, 사회문화활동 참여를 위한 네트워킹, 우울 예방과 운동 및 건강증진 프로그램, 노인학대 예방을 위한 사회적 노력이 필요함을 시사해준다.

• 문화기술의 융합
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• 제5권2호
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• pp.389-395
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• 2019

본 연구는 인체에 유익한 효과가 있고 부작용 없이 장기간 안전하게 사용할 수 있으며 간보호 및 간기능 개선에 탁월한 효과가 있는지 양배추출물의 간보호 효과에 대하여 알아보았다. 약물(APAP)에 의해 유도된 간손상 동물모델에서 수행된 실험에서, 양배추 추출물은 간손상 마커인 AST 및 ALT를 효과적으로 감소시킴으로써 간 보호 및 간 기능 개선 효과를 나타냄을 알 수 있었다. 양배추 추출물은 간질환의 예방 또는 치료용 약학적 추출물로서 유효하다는 것이다. 특히, 양배추 추출물은 간손상에 수반되는 급성 염증 반응에 관여하는 염증 매개체 iNOS 및 COX-2 및 전염증성 사이토카인 $IL-1{\beta}$의 발현을 감소시킴으로써 간염 염증을 치료하는데 효과적이었다. 그 결과, $100{\sim}150^{\circ}C$에서 열처리 한 배추 추출물은 생배추 추출물에 비해 간기능 개선 효과 또는 항염증 효과가 우수 하였다.

• 한국정보통신학회논문지
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• 제25권5호
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• pp.667-676
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• 2021

최근 우리나라의 청소년들은 스마트폰 과사용, 많은 학습량에 따른 신체활동 부족 등으로 인하여 자세 불균형의 위험에 노출되어있다. 또한 코로나 19로 인해 효과적인 비대면 운동 서비스에 대한 니즈가 증가하고 있는 추세이다. 이에 착안해 본 연구에서는 청소년들을 대상으로 둥근 어깨 개선의 효과를 제공하면서 비대면 서비스의 한계를 극복하기 위해 근전도 센서를 활용한 운동 서비스를 제안하고자 한다. 둥근 어깨를 개선할 수 있는 운동 프로그램을 구성하고, 효과적으로 운동할 수 있도록 근전도 센서를 연동한 어플리케이션을 구현하였다. 운동 프로그램은 4주 동안 타깃 근육 부위를 번갈아 가며 운동할 수 있도록 구성했고, 이에 따라 변화하는 근전도 수치를 측정하여 피드백을 제공할 수 있는 기능을 부가했다. 본 연구를 통하여 운동 기반의 자세 교정 디지털 서비스의 바탕을 제공하고, 이를 통하여 불균형한 신체를 개선함으로써 건강 증진의 가능성을 도모하고자 한다.

• 생약학회지
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• 제52권1호
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• pp.1-12
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• 2021

Platycodon (Platycodon grandiflorum) is used as a food and medicinal ingredient worldwide, particularly in Northeast Asia. Although a large number of studies have been conducted to determine its medicinal efficacy, there is still a paucity of literature summarizing the clinical activity of Platycodon. In this systematic review, we aimed to summarize the clinical efficacy of Platycodon. All literature describing the clinical efficacy of Platycodon was collected from international databases, and relevant papers were carefully evaluated for eligibility. Data were extracted from the selected papers and quality evaluation was conducted in accordance with the standards provided by the National Institutes of Health (NIH), with all procedures being conducted in accordance with PRISMA 2009 checklist guidelines. After the removal of 342 papers, 644 studies were fully screened for their titles and abstracts, among which, 19 studies were finally selected for full summarization. Extraction of data indicated evidence of the effectiveness of Platycodon in the treatment of respiratory system-related diseases and cancer, and in the provision of immunity. However, we found that the quality and objectivity of evaluation, management of variable factors, sample size, and reproducibility were generally poor. Although Platycodon has shown potential antiviral, antibacterial, anticancer, and antidepressant effects, and promotion of immunity in clinical settings, it was not possible to integrate objective indicators to conduct a meta-analysis due to the lack of literature and insufficient studies. More investigations in the clinical setting should be conducted to confirm the functional effects of Platycodon.