• BMB Reports
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• v.40 no.4
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• pp.562-570
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• 2007

Soluble or cell-bound IL-1 receptor accessory protein (IL-1RAcP) does not bind IL-1 but rather forms a complex with IL-1 and IL-1 receptor type I (IL-1RI) resulting in signal transduction. Synthetic peptides to various regions in the Ig-like domains of IL-1RAcP were used to produce antibodies and these antibodies were affinity-purified using the respective antigens. An anti-peptide-4 antibody which targets domain III inhibited 70% of IL-$1\beta$-induced productions of IL-6 and PGE2 from 3T3-L1 cells. Anti-peptide-2 or 3 also inhibited IL-1-induced IL-6 production by 30%. However, antipeptide-1 which is directed against domain I had no effect. The antibody was more effective against IL-$1\beta$ compared to IL-$1\alpha$. IL-1-induced IL-6 production was augmented by coincubation with PGE2. The COX inhibitor ibuprofen blocked IL-1-induced IL-6 and PGE2 production. These results confirm that IL-1RAcP is essential for IL-1 signaling and that increased production of IL-6 by IL-1 needs the co-induction of PGE2. However, the effect of PGE2 is independent of expressions of IL-1RI and IL-1RAcP. Our data suggest that domain III of IL-1RAcP may be involved in the formation or stabilization of the IL-1RI/IL-1 complex by binding to epitopes on domain III of the IL-1RI created following IL-1 binding to the IL-1RI.

• Journal of the Korean Society of Radiology
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• v.13 no.4
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• pp.509-516
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• 2019

In the linear transformation method, the original image is divided into a plurality of range blocks, and a partial transform system for finding an optimal domain block existing in the image for each range block is used to adjust the performance of the compression ratio and the picture quality, The nonlinear transformation method uses only the rotation transformation among eight shuffle transforms. Since the search is performed only in the limited domain block, the coding time is faster than the linear transformation method of searching the domain block for any block in the image, Since the optimal domain block for the range block can not be selected in the image, the performance may be lower than other methods. Therefore, the nonlinear transformation method improves the performance by increasing the approximation degree of the brightness coefficient conversion instead of selecting the optimal domain block, The smaller the size of the block, the higher the PSNR value, The higher the compression ratio is increased groups were quadtree block divided to encode the image at best.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.18 no.2
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• pp.348-369
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• 2024

With the advancement of Industry 4.0 and Industrial Internet of Things (IIoT), manufacturing increasingly seeks automation and intelligence. Temperature and vibration monitoring are essential for machinery health. Traditional abnormal state detection methodologies often overlook the intricate frequency characteristics inherent in vibration time series and are susceptible to erroneously reconstructing temperature abnormalities due to the highly similar waveforms. To address these limitations, we introduce synergistic, end-to-end, unsupervised Frequency-Time Domain Memory-Enhanced Autoencoders (FTD-MAE) capable of identifying abnormalities in both temperature and vibration datasets. This model is adept at accommodating time series with variable frequency complexities and mitigates the risk of overgeneralization. Initially, the frequency domain encoder processes the spectrogram generated through Short-Time Fourier Transform (STFT), while the time domain encoder interprets the raw time series. This results in two disparate sets of latent representations. Subsequently, these are subjected to a memory mechanism and a limiting function, which numerically constrain each memory term. These processed terms are then amalgamated to create two unified, novel representations that the decoder leverages to produce reconstructed samples. Furthermore, the model employs Spectral Entropy to dynamically assess the frequency complexity of the time series, which, in turn, calibrates the weightage attributed to the loss functions of the individual branches, thereby generating definitive abnormal scores. Through extensive experiments, FTD-MAE achieved an average ACC and F1 of 0.9826 and 0.9808 on the CMHS and CWRU datasets, respectively. Compared to the best representative model, the ACC increased by 0.2114 and the F1 by 0.1876.

• Journal of Korean Public Health Nursing
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• v.15 no.2
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• pp.275-284
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• 2001

In order to assess the knowledge and learning needs. 72 patients with the first onset myocardial infarction were interviewed by the structured questionnaires during the period of September, 1999 to July, 2000. The results were as follows 1. As a whole. $57.9\%$ of patient had correct knowledge in relation to myocardial infarction. As for the knowledge score in terms of general characteristics, the patients who were in higher education and living with spouse were significantly higher point than those who were in lower education and living alone. 2. The mean scores of learning need of the subjects was 4.13 measured by Likert 5 point scale, No significant differences were shown in the score of learning need in terms of the general characteristics. As for the learning need according to domain, the subjects had higher leaning needs in the domain of diet, risk factors and activity and exercise. 3. There was no significant correlation between the learning need and the knowledge of myocardial infarction. The results of finding show that education program should be consider the general characteristics. the level of knowledge and learning needs of the myocardial infarction patients.

• Korean Journal of Health Education and Promotion
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• v.21 no.1
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• pp.217-242
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• 2004

This study was carried out to measure job satisfaction and quality of life and to clarify the factors in job satisfaction which influence on quality of life of dental technicians, using developed tools for job satisfaction and WHOQOL-BREF for quality of life. The subjects for this study were 238 people who worked the in the Daegu-Kyungbuk area. The results of this study were as follows； the general characteristics that influenced job satisfaction, were especially education, hobbies, salary level, job career and work hours. The factors that influenced the quality of life, were especially Married status, hobbies, job position, and office hours. All subfactors in job satisfaction were related to each other. Growth-development factor was intensely related with recognition factor. Also, all subfactors in quality of life were in positive relation to each other, especially psychological domain was highly related with social domain. Factors of safety, recognition and accomplishment in job satisfaction intensely affected quality of life. Therefore, It is suggested that social recognition for dental technician should be promoted and it might be needed to adjust office hours and support hobby life.

• Journal of Korean Academy of Nursing
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• v.31 no.5
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• pp.897-911
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• 2001

The purpose of the study was to compare home care nursing intervention activities analyzed by the Nursing Intervention Classification (NIC) system for hospice and general patients. Method: For the descriptive survey study, data was collected by reviewing charts of 151 hospice patients and 421 general patients who registered in the department of home health care nursing at K Hospital. Results: According to the NIC system application, there were 2380 total nursing interventions used for the hospice patients and 8725 for the general home care patients. For both sets of patients (hospice vs. general), the most frequently used nursing intervention in level 1 was the Physiological: Complex domain (40.13 vs. 31.06 percent), followed by the Safety domain; in level 2, the Risk Management class (28.4 vs. 27.70 percent), followed by Tissue Perfusion Management; and in level 3, Vital Sign Monitoring (6.18 vs. 4.84 percent), followed by Health Screening. Conclusion: The study showed that there was a lack of specialized hospice nursing interventions such as emotional, family and spiritual support, and care for dying hospice patients.

• Child Health Nursing Research
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• v.15 no.4
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• pp.375-382
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• 2009

Purpose: The purpose of this study was to examine the relation between parenting stress and depression in mothers of infants and verbal abuse. Methods: The data for this study was collected from 174 mothers of infants 12 to 48 months old who either used one of two pediatric clinics or one kindergarten. The instruments used for this study were a self-report questionnaire, PSI (Parenting Stress Index Short Form by Abidin), BDI (Beck Depression Instrument) and Verbal Abuse Measure. Regression analysis was the statistical method used for data analysis. Results: The mean score for depression in the mothers was 14.7 (range: 2-35), for parenting stress, 81.86 (range: 44-142), and for verbal abuse, 37.9 (range: 25-79). There were significant positive correlations for depression, parenting stress and verbal abuse in the mothers. Significant factors influencing verbal abuse were child domain, parent-child domain. Conclusion: The results of this study suggest that there is a need to design interventions and develop programs for depression management and parenting stress for mothers of infants between 12 and 48 months.

• Korean Journal of Adult Nursing
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• v.14 no.4
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• pp.501-509
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• 2002

Purpose: This study was performed to identify the illness intrusiveness, quality of life, and their relationships in patients with chronic liver disease. Method: Data was collected using scales of illness intrusiveness developed by Devins et al and Korean health related quality of life (KoQoLS) developed by Shim et al to measure the illness intrusiveness and quality of life from 141 chronic liver disease patients. Result: The total mean score of illness intrusiveness was $38.85{\pm}18.45$. The domain of illness intrusiveness which showed the highest mean score was health ($4.60{\pm}2.02$), and the lowest mean score domain was relationship with spouse ($20.4{\pm}1.69$). The subcategory of KoQoLS which showed the highest mean score was bodily pain ($6.96{\pm}2.98$), and the lowest mean score subcategory was vitality ($2.75{\pm}1.20$). There were negative relationships between illness intrusiveness and KoQoLS in all subcategories. Abovel all, Illness intrusiveness had the strongest negative relationship with role limitation (r=-0.641) among the KoQoLS subcategories. Conclusion: Because the illness intrusiveness had negative influence on the quality of life in patients with chronic liver disease, further research will need to specify detailed illness intrusiveness and to explore influencing factors on quality of life in them.

• Journal of the Korean Society of Physical Medicine
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• v.10 no.3
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• pp.47-55
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• 2015

PURPOSE: Stoke is one of most common disabling conditions and it is still lacking of measuring patient's functioning level. The aim of the study was to develop Korean language version of stroke impact scale 3.0. METHODS: Korean version of stroke impact scale 3.0 was developed in idiomatic modern Korean with a standard protocol of multiple forward and backward translations and an expert reviews to achieve equivalence with the original English version. Interviews with clinicians who were currently managing patients with stroke were also conducted for language evaluation. A reliability test was performed to make final adaptation using a pre-final version. To assess the reliability of the translated questionnaire, the intraclass correlation coefficient (ICC) was calculated for each domain of the scale. RESULTS: Thirty subjects (16 male, 14 female) aged from 20 to 75 years old participated to review the translated questionnaire. Reliability of each domain of the questionnaire was found to be good in strength (ICC=0.74), ADL (ICC=0.81), mobility (ICC=0.90), hand function (ICC=0.80) and social participation (ICC=0.79), communication (ICC=0.77) with total (ICC=0.76). However, domains of memory and thinking (ICC=0.66), and emotion (ICC=0.27) and showed poor reliability. CONCLUSION: This study indicates that the Korean version of SIS 3.0 was successfully developed. Future study needed for obtaining the validity of the Korean version of SIS 3.0.

• Korean Journal of Occupational Health Nursing
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• v.24 no.4
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• pp.259-269
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• 2015

Purpose: The study is to identify a correlation among hospital nurses' emotional labor, social support and organizational commitment and to analyze the effects on organizational commitment. Methods: The participants are 300 nurses working at two general hospitals located in Gyeonggi-do, who agreed to join the study. Data collection were done from July to September in 2014. The collected data are analyzed a descriptive statistic, t-test, ANOVA, $Scheff{\acute{e}}$ test, Pearson's correlation coefficient, and multiple regression and SPSS/WIN 15.0 Program was used in the process. Results: Organizational commitment was negatively correlated with emotional works but it was positively correlated with social support. The factors affecting organizational commitment were informational support and evaluative support which were sub-domain of social support as well as level of emotional expression which was a sub-domain of emotional works, their positions and level of education. Conclusion: To increase the level of an organizational commitment, a method of coping in difficult situations and information relating to private assessments is recommended. Also, the organization should prepare a plan that members can properly manage their emotions face-to-face with clients.