• Title/Summary/Keyword: Health damage

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The Beneficial Effects of Vitamin E on the Irradiation-induced Testis Damage

  • Ahn, Seung-Ju;Kim, Kgu-Hwan
    • Biomedical Science Letters
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    • v.17 no.3
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    • pp.239-243
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    • 2011
  • Radiation exposure may cause tissue damage by ionized or excited atoms. The molecules are transformed from water or they directly interact with cells. Antioxidants such as vitamin E, vitamin C are used to reduce the interference of radiation. Especially, vitamin E inhibits the formation and accumulation of lipid and oxidation and the activity of drug-metabolizing enzymes. After irradiation of 3 Gy to the testis, the entire shape of testis was partly depressed and an irregular vacuole was observed to the edge. The 3 Gy group after treatment with vitamin E showed the low destruction of spermatogonia and partial tissue damage as compared to the 3 Gy group. Vitamin E inhibited the production of vacuoles from the cell death and generated the block to prevent the condensation of the seminiferous tubules.

Statistical approach to a SHM benchmark problem

  • Casciati, Sara
    • Smart Structures and Systems
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    • v.6 no.1
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    • pp.17-27
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    • 2010
  • The approach to damage detection and localization adopted in this paper is based on a statistical comparison of models built from the response time histories collected at different stages during the structure lifetime. Some of these time histories are known to have been recorded when the structural system was undamaged. The consistency of the models associated to two different stages, both undamaged, is first recognized. By contrast, the method detects the discrepancies between the models from measurements collected for a damaged situation and for the undamaged reference situation. The damage detection and localization is pursued by a comparison of the SSE (sum of the squared errors) histograms. The validity of the proposed approach is tested by applying it to the analytical benchmark problem developed by the ASCE Task Group on Structural Health Monitoring (SHM). In the paper, the results of the benchmark studies are presented and the performance of the method is discussed.

Realtime Detection of Damage in Composite Structures by Using PVDE Sensor (압전고분자 센서를 이용한 복합재 구조의 실시간 손상탐지)

  • ;Y. A. Dzenis
    • Proceedings of the Korean Society For Composite Materials Conference
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    • 2002.10a
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    • pp.118-121
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    • 2002
  • Polyvinylidene di-fluoride (PVDF) film sensor appeared to be practically useful for the structural health monitoring of composite materials and structures. PVDF film sensors were either attached to or embedded in the graphite/epoxy composite (CFRP) samples to detect the fatigue damage at the bondline of single-lap joints or the tensile failure of unidirectional laminates. PVDF sensors were sensitive enough to detect and determine the crack front in linear location since composites usually produce very energetic acoustic emission (AE). PVDF sensors are extremely cost-effective, as flexible as other plastic films, in low profile as thin as a few tens of microns, and have relatively wide-band response, all of which characteristics are readily utilized for the structural health monitoring of composite structures. Signals due to fatigue damage showed a characteristics of mode II (shear) type failure whereas those from fiber breakage at DEN notches showed that of mode I (tensile) type fracture.

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Identification of reinforced concrete beam-like structures subjected to distributed damage from experimental static measurements

  • Lakshmanan, N.;Raghuprasad, B.K.;Muthumani, K.;Gopalakrishnan, N.;Basu, D.
    • Computers and Concrete
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    • v.5 no.1
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    • pp.37-60
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    • 2008
  • Structural health monitoring of existing infrastructure is currently an important field of research, where elaborate experimental programs and advanced analytical methods are used in identifying the current state of health of critical and important structures. The paper outlines two methods of system identification of beam-like reinforced concrete structures representing bridges, through static measurements, in a distributed damage scenario. The first one is similar to the stiffness method, re-cast and the second one to flexibility method. A least square error (LSE) based solution method is used for the estimation of flexural rigidities and damages of simply supported, cantilever and propped cantilever beam from the measured deformation values. The performance of both methods in the presence of measurement errors is demonstrated. An experiment on an un-symmetrically damaged simply supported reinforced concrete beam is used to validate the developed method. A method for damage prognosis is demonstrated using a generalized, indeterminate, propped cantilever beam.

Hybrid Damage Detection in Prestressed Concrete Girder Bridges (프리스트레스트 콘크리트 거더교의 하이브리드 손상 검색)

  • Hong, Dong-Soo;Lee, Jung-Mi;Na, Won-Bae;Kim, Jeong-Tae
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2007.04a
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    • pp.669-674
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    • 2007
  • To develop a promising hybrid structural health monitoring (SHM) system, a combined use of structural vibration and electro-mechanical (EM) impedance is proposed. The hybrid SHM system is designed to use vibration characteristics as global index and EM impedance as local index. The proposed health monitoring scheme is implemented into prestressed concrete (PSC) girder bridges for which a series of damage scenarios are designed to simulate various prestress-loss situations at which the target bridges car experience during their service life. The measured experimental results, modal parameters and electro-magnetic impedance signatures, are carefully analyzed to recognize the occurrence of damage and furthermore to indicate its location.

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Effects of Reactive Oxygen Species on DNA Stability in Humnn Spermatozoa

  • Kang, Hee-Gyoo;Kim, Tai-Jeon;Bae, Hyung-Joon;Moon, Hi-Joo;Kim, Myo-Kyung;Kim, Dong-Hoon;Sungwon-Han;Lee, Ho-Joon;Yang, Hye-Young
    • Biomedical Science Letters
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    • v.7 no.4
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    • pp.181-190
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    • 2001
  • This study was designed to investigate the effects of reactive oxygen species (ROS) on DNA stability in human spermatozoa. To verify human spermatozoa were incubated with xanthine-xanthine oxidase (X 100$\mu$M-XO 50 mlU ~ 400 mIU), $H_2O_2$ (125 $\mu$M ~ 1 mM), sodium nitroprusside (SNP 0.1 $\mu$M ~ 100 $\mu$M) or lymphocyte. Otherwise, spermatozoa were incubated under low $O_2$ (5%) condition. Damage of sperm DNA was analyzed by single cell electrophoresis (Comet assay) and flow cytometry after acridine orange staining. In the presence of ROS, there was increase in DNA damage. The rate of DNA single strand breakage (9.0$\pm$1.0% ~ 46.0$\pm$4.6%) and DNA fragmentation (7.51$\pm$1.0% ~ 29.5$\pm$4.6%) were similar regardless of the kinds of ROS and exposure time. DNA damage in the lower $O_2$ condition (5%) was lower than ambient $O_2$ condition (20%). Taken together, it suggested that sperm DNA might be damaged by ROS. In the presence of ROS, increase in DNA damage and chromatin instability was obvious in spite of short exposure. Although present study reconfirmed that sperm incubation in the low concentration of ROS have the benefit m the induction of capacitation and Ah, the increase in DNA damage by ROS and possible genetic problem should be considered before the human trials.

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Information entropy based algorithm of sensor placement optimization for structural damage detection

  • Ye, S.Q.;Ni, Y.Q.
    • Smart Structures and Systems
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    • v.10 no.4_5
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    • pp.443-458
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    • 2012
  • The structural health monitoring (SHM) benchmark study on optimal sensor placement problem for the instrumented Canton Tower has been launched. It follows the success of the modal identification and model updating for the Canton Tower in the previous benchmark study, and focuses on the optimal placement of vibration sensors (accelerometers) in the interest of bettering the SHM system. In this paper, the sensor placement problem for the Canton Tower and the benchmark model for this study are first detailed. Then an information entropy based sensor placement method with the purpose of damage detection is proposed and applied to the benchmark problem. The procedure that will be implemented for structural damage detection using the data obtained from the optimal sensor placement strategy is introduced and the information on structural damage is specified. The information entropy based method is applied to measure the uncertainties throughout the damage detection process with the use of the obtained data. Accordingly, a multi-objective optimal problem in terms of sensor placement is formulated. The optimal solution is determined as the one that provides equally most informative data for all objectives, and thus the data obtained is most informative for structural damage detection. To validate the effectiveness of the optimally determined sensor placement, damage detection is performed on different damage scenarios of the benchmark model using the noise-free and noise-corrupted measured information, respectively. The results show that in comparison with the existing in-service sensor deployment on the structure, the optimally determined one is capable of further enhancing the capability of damage detection.

Hybrid Structural Health Monitoring of Steel Plate-Girder Bridges using Acceleration-Impedance Features (가속도-임피던스 특성을 이용한 강판형교의 하이브리드 구조건전성 모니터링)

  • Hong, Dong-Soo;Do, Han-Sung;Na, Won-Bae;Kim, Jeong-Tae
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.29 no.1A
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    • pp.61-73
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    • 2009
  • In this paper, hybrid health monitoring techniques using acceleration-impedance features are newly proposed to detect two damage-type in steel plate-girder bridges, which are girder's stiffness-loss and support perturbation. The hybrid techniques mainly consists of three sequential phases: 1) to alarm the occurrence of damage in global manner, 2) to classify the alarmed damage into subsystems of the structure, and 3) to estimate the classified damage in detail using methods suitable for the subsystems. In the first phase, the global occurrence of damage is alarmed by monitoring changes in acceleration features. In the second phase, the alarmed damage is classified into subsystems by recognizing patterns of impedance features. In the final phase, the location and the extent of damage are estimated by using modal strain energy-based damage index method and root mean square deviation (RMSD) method. The feasibility of the proposed hybrid technique is evaluated on a laboratory-scaled steel plate-girder bridge model for which hybrid acceleration-impedance signatures were measured for several damage scenarios. Also, the effect of temperature on the accuracy of the impedance-based damage monitoring results are experimentally examined from combined scenarios of support damage cases and temperature changes.

Research on Consciousness for General Infectious Disease Prevention and Sterilization Mediated by Vermin (전염병의 매개체인 해충의 피해 예방 및 소독에 대한 의식 조사 연구 - 위생 관련 산업체 종사자와 일반업체 종사자를 대상으로 의식 차이 비교 분석 -)

  • Kim, Hae-Ja;Bae, Ci-Ae;Rha, Young-Ah
    • Culinary science and hospitality research
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    • v.12 no.2 s.29
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    • pp.151-167
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    • 2006
  • This study shows the differences among residents’ consciousness for general infectious disease and sterilization mediated by vermin. We categorized both industry-related people who work in restaurants, hygiene service shops, whole sales, government organizations, PC shops, factories, department stores and non-industry-related people who work in schools, general offices into two groups for this study. The discovery of vermin held 86% of total exam cases. The vermin included mosquitoes, cockroaches, ants, flies, and so on. People thought these vermin might mediate bacteria infection to human. 80.3% of persons thought mite might exist in blankets, beds and couches. Among 66.6% of total experience of vermin damage, the main damage came from mosquitoes. Frequently used methods of prevention from vermin damage were as follows: "spray of effective chemicals", "install traps" and " report to a prevention company" in order. It indicated that people did not take special actions to repel vermin in spite of their knowing seriousness of damage. Furthermore, just half cases were executed regular sanitization.

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Embedment of structural monitoring algorithms in a wireless sensing unit

  • Lynch, Jerome Peter;Sundararajan, Arvind;Law, Kincho H.;Kiremidjian, Anne S.;Kenny, Thomas;Carryer, Ed
    • Structural Engineering and Mechanics
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    • v.15 no.3
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    • pp.285-297
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    • 2003
  • Complementing recent advances made in the field of structural health monitoring and damage detection, the concept of a wireless sensing network with distributed computational power is proposed. The fundamental building block of the proposed sensing network is a wireless sensing unit capable of acquiring measurement data, interrogating the data and transmitting the data in real time. The computational core of a prototype wireless sensing unit can potentially be utilized for execution of embedded engineering analyses such as damage detection and system identification. To illustrate the computational capabilities of the proposed wireless sensing unit, the fast Fourier transform and auto-regressive time-series modeling are locally executed by the unit. Fast Fourier transforms and auto-regressive models are two important techniques that have been previously used for the identification of damage in structural systems. Their embedment illustrates the computational capabilities of the prototype wireless sensing unit and suggests strong potential for unit installation in automated structural health monitoring systems.