Biomedical Science Letters (대한의생명과학회지)

The Korean Society for Biomedical Laboratory Sciences (대한의생명과학회)
권호 표지

The Beneficial Effects of Vitamin E on the Irradiation-induced Testis Damage

  • Ahn, Seung-Ju (Department of Clinical Pathology, Daegu Health College) ;
  • Kim, Kgu-Hwan (Department of Radiologic Technology, Daegu Health College)
  • ;
  • 김구환 (대구보건대학 방사선과)
  • Received : 2010.11.17
  • Accepted : 2011.07.09
  • Published : 2011.09.30
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Abstract

Radiation exposure may cause tissue damage by ionized or excited atoms. The molecules are transformed from water or they directly interact with cells. Antioxidants such as vitamin E, vitamin C are used to reduce the interference of radiation. Especially, vitamin E inhibits the formation and accumulation of lipid and oxidation and the activity of drug-metabolizing enzymes. After irradiation of 3 Gy to the testis, the entire shape of testis was partly depressed and an irregular vacuole was observed to the edge. The 3 Gy group after treatment with vitamin E showed the low destruction of spermatogonia and partial tissue damage as compared to the 3 Gy group. Vitamin E inhibited the production of vacuoles from the cell death and generated the block to prevent the condensation of the seminiferous tubules.

Keywords

References

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