• Title/Summary/Keyword: Healing condition

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Analysis of optimal activities according to thermal comfort in the forest: focusing on a program for the elderly at the National Forest Therapy Center

  • Tae-Gyu Khil;Ah-Young Jung;Kun-Woo Park;Yang-Soon Oh;Beom Lee;Dawou Joung;Hyelim Lee;Bum-Jin Park
    • Korean Journal of Agricultural Science
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    • v.50 no.4
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    • pp.663-673
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    • 2023
  • The purpose of this study was to scientifically activate the forest healing program activities for the elderly. The predicted mean vote (PMV) and predicted percentage of dissatisfied (PPD), which are indices of thermal comfort in the thermal environment, and degree of canopy closure were compared and analyzed. Based on this information, the study objective was to present the appropriate conditions for maintaining the best comfort for the elderly. Six deck road shelters, which are the most active locations in forest healing programs among the National Center for Forest Therapy, were selected as the study sites. The results indicated that in the case of the conditions of 1 clo (clothing insulation value) and 1 met (metabolic rate) at an air temperature of 19 to 21 degrees in September on the measurement date, the PMV values ranged between -1.85 and -0.98 at all sites, and PPD values ranged between 25.60% and 68.68%. On the other hand, in the case of 1.3 clo and 1.6 met conditions, the PMV values ranged between -0.08 and 0.23 for all sites and PPD values ranged between 5.40 and 6.18. As shown above, the difference in thermal environment comfort and satisfaction according to the condition of the amount of metabolism and the amount of clothing could be confirmed. In addition, an analysis of the relation between PPD and canopy closure suggested a significantly positive correlation between them, and it was found that canopy closure was a factor affecting thermal comfort. Studies on effects of forest thermal environmental comfort and canopy closure on forest healing program areas should be conducted extensively according to seasonal conditions to provide information that can be used for more effective forest healing programs.

Human collagen alpha-2 type I stimulates collagen synthesis, wound healing, and elastin production in normal human dermal fibroblasts (HDFs)

  • Hwang, Su Jin;Ha, Geun-Hyoung;Seo, Woo-Young;Kim, Chung Kwon;Kim, KyeongJin;Lee, Sang Bae
    • BMB Reports
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    • v.53 no.10
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    • pp.539-544
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    • 2020
  • Skin aging appears to be the result of overlapping intrinsic (including genetic and hormonal factors) and extrinsic (external environment including chronic light exposure, chemicals, and toxins) processes. These factors cause decreases in the synthesis of collagen type I and elastin in fibroblasts and increases in the melanin in melanocytes. Collagen Type I is the most abundant type of collagen and is a major structural protein in human body tissues. In previous studies, many products containing collagen derived from land and marine animals as well as other sources have been used for a wide range of purposes in cosmetics and food. However, to our knowledge, the effects of human collagen-derived peptides on improvements in skin condition have not been investigated. Here we isolate and identify the domain of a human COL1A2-derived protein which promotes fibroblast cell proliferation and collagen type I synthesis. This human COL 1A2-derived peptide enhances wound healing and elastin production. Finally, the human collagen alpha-2 type I-derived peptide (SMM) ameliorates collagen type I synthesis, cell proliferation, cell migration, and elastin synthesis, supporting a significant anti-wrinkle effect. Collectively, these results demonstrate that human collagen alpha-2 type I-derived peptides is practically accessible in both cosmetics and food, with the goal of improving skin condition.

A study on the Healing Mechanism of Herbal Medicine, Oryoungsan (오령산의 작용기전(作用機轉)에 대한 고찰(考察))

  • Nam, Hyoung-sin;Cho, Chung-sik;Kim, Chul-jung
    • Journal of Haehwa Medicine
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    • v.10 no.1
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    • pp.157-166
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    • 2001
  • Oryoungsan which first recorded in Sanghanron, the clinical medical book consists of treating acute febrile disease according to its change, is one of the frequently used oriental medicines. these days, it has been prescribed in symptoms accompanied by edema mostly. therefore it is easy to consider it as a type of diuretics. In Sanghanron it was originally used in the symptoms of perspiration, decreased urine volume, thirsty, flatulence. these symptoms indicate loss of body fluid and the prescription which orders "taking warm water sufficiently" supports this. On this background, it is supposed that Oryoungsan treats dehydration after providing water and electrolytes. To consider that herbal medicines consisted of Oryoungsan make electrolytes go out of the body, The healing mechanism of dehydration doesn't meet this. Because Oryoungsan was used in condition of fever or in similar condition, it is more resonable to understand that restoration of increasing blood flow to the subcutaneous venous plexus regulating body temperature in febrile condition into body circulation, resulting into maintaining main blood volume and into treating decreased urine volume and thirsty is Oryoungsan's function in the dehydration or febrile condition. That is, symptoms are decreased or disappeared through restoring unbalance of internal body fluid. The other target is pain controls, especially chronic headache, facial pain and trigeminal neuralgia. it is suggested that the function of pain control of Oryoungsan is related to 5-HT(5-hydroxytrypamine), nerve transmitter in the endogenous analgesic system. Moreover it is also suggested that Oryoungsan is relate to 5-HT, considering the fact that gastroparesis, a symptom of cyclic vomiting syndrome treated with 5-HT1D receptor agonist is similar to the 'bi', symptoms appeared in the Oryoungsan-related disease.

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Initial Changes of Implant Stability from Installation during Early Bone Healing (임플란트 식립 후 초기 안정성의 변화)

  • Park, Chan-Jin;Kim, Dae-Gon;Cho, Lee-Ra
    • Journal of Dental Rehabilitation and Applied Science
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    • v.29 no.3
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    • pp.272-279
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    • 2013
  • The concept of implant stability was basically originated from the relative condition of bone-implant interface and has some meanings for evaluation of that interface. In addtion, it has been used for the investigation of initial bone healing process after fixture installation because a degree of micromotion around interface can affect unfavorable clinical results. The purpose of this study is to investigate the mode of initial bone healing from fixture installation through prospective trial. Thirty fixtures were consecutively installed in mandibles of 26 patients with single tooth loss area and then healing abutment were secured for one-stage surgery meothod. Resonance frequency analysis was performed with one week interval during 12 weeks and periapical radiographs were taken at each month. Although marginal bone level change was not shown through observation period (P>0.05), statistical difference of implant stability was shown through 4 and 6 week (P<0.05) and was not shown after 6 week (P>0.05) according to the bone quality. Initial bone healing process is a successive process of bone resorption and favorable bone healing result might be postulated at 4 week interval after installation through RFA.

A Study on the Conceptual Change and Utilization of the Lobby Space in General Hospitals (국내 종합병원 로비공간의 개념변화와 이용실태에 관한 조사연구)

  • Phyo, Jun-Woo;Yang, Nae-Won
    • Korean Institute of Interior Design Journal
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    • no.34
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    • pp.86-95
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    • 2002
  • In the 1950’s, after modernistic hospital is begun to build in our country, there were much changes in hospital construction plan such as function, scale, operation, technology for 40 years so far. Interest about 'Healing environment furtherance' which is one of basic function of hospital within these change is continued. Specially, concept about furtherance of healing environment limited in ward department in the early time is applied to hospital space magnificently whole coming at present. Entrance of hospital and change of Lobby may speak as the representative example. This interest about practically use of lobby is rising gradually. Lobby adds to existed concept of space to the importance revaluated. The first purpose of this study is to investigates main entrance and lobby of representative hospital in our country and to search change and present condition. The second purpose is hereupon to present necessary objective standard with direction of lobby plan in general hospital forward though this.

High Temperature and Fatigue Strength of crack-healed Mullite/Silicon Carbide Ceramics (균열 치유된 Mullite/SiC 세라믹스의 고온강도와 피로강도)

  • Ando, K.;Chu, M.C.;Tsuji, K.;Sato, S.
    • Journal of Power System Engineering
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    • v.6 no.1
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    • pp.88-95
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    • 2002
  • 본 연구에서는 균열 치유 거동을 가지는 소결된 Mullite/SiC의 모재, 열처리재, 균열재, 치유 균열재의 기계적 특성이 논의되었다. 반타원형 균열의 치수는 $100{\mu}m$$200{\mu}m$이다. 얻어진 결과는 다음과 같다. (a) Mullite/SiC 복합 세라믹스는 균열 치유 능력이 있었다. (b) 최적의 균열 치유 열처리 조건은 $1300^{\circ}C$, 1시간이었다. (c) 치유 가능한 최대 균열 길이는 직경 $100{\mu}m$의 반타원 균열이다. (d) 균열 치유부는 $1200^{\circ}C$이상에서 충분한 강도를 가졌고, 대부분의 시험편은 균열 치유부 이외의 영역에서 파단 하였다. (e) 공기중에서 예열처리는 본 재료의 피로강도 향상에 유용하였다.

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Finite element analysis of tissue differentiation process in fractured bones applied by a composite IM-rod based on a mechano-regulation theory (메카노 규제 이론에 기초한 복합재료 IM-rod가 적용된 골절부의 세포분화과정의 유한요소해석)

  • Son, Dae-Sung;Mehboob, Hassan;Chang, Seung-Hwan
    • Composites Research
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    • v.25 no.5
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    • pp.136-140
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    • 2012
  • This paper describes the bone healing process of fractured long bones such as a tibia applied by composite IM rods using finite element analysis. To simulated tissue differentiation process mechano-regulation theory with a deviatoric strain was implemented and a user's subroutine programmed by a Python code for an iterative calculation was used. To broadly find the appropriate rod modulus for healing bone fractures, composite IM rods were analyzed considering the stacking sequence. To compare mechanical stimulation at fracture gap, two kinds of initial loading conditions were applied. As a result, it was found that the initial loading condition was the most sensitive factor for the healing performance. In case a composite IM rod made of a plain weave carbon fiber/epoxy (WSN3k) had a stacking sequence of $[{\pm}45]_{nT}$, the healing efficiency was the most effective under a initial load of 10%BW.

BONE HEALING CAPACITY IN THE FRACTURE OF RABBIT MANDIBULAR BONE USING LOW-LEVEL LASER (가토 하악골 절단부의 저수준 레이저 처치가 골치유에 미치는 영향)

  • Bae, Yong-Hyeon;Han, Se-Jin;Kim, Kyung-Wook
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.35 no.2
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    • pp.120-124
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    • 2009
  • The concept of biostimulation of wounds by low-level laser therapy(LLLT) is attracting considerable attention. Although its effect on whole tissues has been studied quite extensively, the biological and cellular mechanisms underlying LLLT have not been clarified. In an experimental radius fracture in rabbits, Tang and Chai reported that LLLT enhanced the activity of red blood cells, macrophages, fibroblasts, chondrocytes, and osteoclasts within the fracture area. The purpose of the present study was to evaluate the effect of LLLT with a GaAlAs diode laser device on bone healing in rabbit mandibular fractures. We use 12 rabbits for this study. All rabbits were fractured mandible angle area using saw in anesthetic condition. In control group(n=6), none treatment was performed at fracture site. In experimental group(n=6), LLLT with a GaAlAs diode laser was radiated at fracture site daily for 7 days. All rabbits were sacrificed at 6 weeks later from performed fracture day. We studied the immunohistochemical staining of CD34 and Vimentin and the histochemical analysis for calcium and phosphorus content. The results were as follows. 1. In the histological and immunohistological staining, after 6week, fibroblasts, osteogenic cells and collgen fibers were observed more in experimental group than in control group. 2. In the histochemical analysis, the amount of calcium and phosphorus contents of the experimental group were more than the control group. From the results obtained, we suggest that the bone healing is stimulated by low-level laser irradiation in bone fractures.

Thermographic Evaluation of Beating Process of Experimentally Induced Infectious Arthritis in Horses (실험적으로 유발한 말 감염성 관절염의 치유경과에 대한 체열학적 평가)

  • Yang Young-Jin;Nam Tchi-Chou
    • Journal of Veterinary Clinics
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    • v.23 no.1
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    • pp.22-30
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    • 2006
  • This study was carried out to assess the usefulness of thermography for diagnosis and healing process of musculoskeletal disorder in horses. Horses with experimentally induced infectious arthritis were treated with bee venom or antibiotics for 5 weeks from 24 hours after inoculation of Staphylococcus aureus, the effectiveness of the 2 therapeutic drugs treatment was similar to each other. Thermographic evaluation was similar to any other tests, because the thermal pattern tend to return to normal with declining similar to those of clinical signs, laboratory experiments and healing of the lesion. This ability to assess inflammatory change noninvasively make thermography an ideal imaging tool to aid in the diagnosis of certain lameness condition or musculoskeletal disease in horses. These results suggested that thermographic evaluation in horses with musculoskeletal disorders were useful for diagnosis and helpful for monitoring of healing process.

Effect of a Mixture of Centella asiatica and Rosamarinus officinalis Leaf Extracts on Delayed Cortisol-induced Keratinocyte Migration (병풀과 로즈마리 잎 추출 혼합물의 코티솔로 유도된 각질형성세포 이동지연에 미치는 영향)

  • WonTae Jo;Miji Yeom;ShinHwan Cho;Eunae Cho;Deokhoon Park;Eunsun Jung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.50 no.2
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    • pp.111-118
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    • 2024
  • A key component of wound healing is epithelialization, which involves the proliferation and migration of epidermal keratinocytes surrounding the wound. Increasing cortisol, a stress hormone, is known to slow the healing process by inhibiting cell proliferation and migration. This study aims to develop an ingredient that can promote delayed wound healing by cortisol through a combination of Centella asiatica (C. asiatica), known for its excellent wound healing effect, and Rosamarinus officinalis (R. officinalis) leaf known for their antipsychotic effect. R. officinalis leaf extract was found to inhibit the activity of 11β-HSD1, an enzyme involved in the production of cortisol. A combination of C. asiatica and R. officinalis leaf extracts (AlfaCalm) was found to enhance cortisol induced delayed keratinocyte migration to a greater extent than C. asiatica extract. AlfaCalm enhanced the expression of CDC42 and the formation of filopodia, which are crucial for the relaxation of the actin skeleton. These results suggest that AlfaCalm can be used as an effective wound healing material in stress condition.