• Journal of Korean Society of Industrial and Systems Engineering
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• v.12 no.20
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• pp.123-138
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• 1989

The primary objective of the agency research in the game theory lives in the maintenance of Pareto is optimal condition for the optimal incentive contract. The basic concepts which are related to this objective are reviewed in connection with the general assumptions to model it, the moral hazard and adverse selection which arised from the information asymmetry, and finally the problem of risk distribution. The demand for auditing and the role of auditor have been addressed by ASOBAC. Issues which an auditor is explicitly introduced in a principal-agent framework have been addressed in this paper. These issues must be confronted to appropriately with the auditor, and to achieve an adequate understanding of optimal confronting arrangement with the auditor. The first step in introducing an auditor into this analysis is to examine the game-theoretic foundation of such a expended agency model. The Mathematical program formulated may not yield solution that are resonable. This arises because the program may call for the auditor and manager to play dominated Nash equilibra in some subgame. The nontrivial natures of the subgame implies that randomized strategies by the auditor and manager nay be of crucial importance. The possibilities for overcoming the randomized strategy problem were suggested; change the rule of the game and or impose covexity condition. The former seems unjustifiable in on auditing context, and the latter promising but difficult to achieve. The discussion ended with an extension of the revelation principle to the owner manager-auditor game, assuming strategies. An examination of the restriction and improvement direction of the basic concept of agency theory was addressed in the later part of this paper. Many important aspects of auditor incentives are inherently multiple-agent, multiple-period, multiple-objectine, phenomena and require further analyses and researches.

• Journal of Convergence for Information Technology
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• v.10 no.10
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• pp.128-134
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• 2020

Recently, the damages by typhoons and heavy rains are increasing due to the climate change. However, we are still vulnerable to inundation disaster due to various causes such as poor physical flood control and lacks of disaster and safety management. Therefore, it is necessary to establish systems to ensure safety and prepare practical countermeasures that can minimize damage when an inundation occurs, thereby minimizing economic loss and casualty. In this study, hydrodynamic inundation modelings were implemented to analyze the "Noryangjin reservoir inundation accident" and "Choryang No. 1 underground road inundation accident." and spatial risk was assessed by a quantitative hazard index. In addition, cause and effect diagrams were provided to present the risk causes in terms of physical and managemental aspects.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.3917-3921
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• 2016

Background: The association between calcium channel blockers (CCBs) and survival in cancer patients remains unclear and the results of related studies are conflicting. The objective of the study was to investigate the association between calcium channel blockers (CCBs) use and survival in cancer patients. Materials and Methods: We searched PubMed, EMBASE, Web of Science and Cochrane Library for studies published before January 2016 with the terms related to CCBs and survival in cancer patients. The information was reviewed and extracted by two evaluators independently. Data of publications was extracted and calculated into hazard ratios (HRs) for overall survival (OS). Statistical analysis was performed by using Review Manager 5.3. Results: There were 11 studies included in our meta-analysis. Analysis of all studies showed that CCBs use was not associated with survival in cancer patients (HR=1.07; 95% CI: 0.91-1.25; P=0.42). No association between CCBs use and overall survival in cancer patients was existed whether in Asian (HR=1.18, 95% CI: 0.72-1.93; P=0.52) or Caucasian population (HR=1.03, 95% CI: 0.89-1.20; P=0.66). Conclusions: There is no evidence that CCBs use is associated with a better or worse outcome of survival in cancer patients.

• Journal of Environmental Policy
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• v.8 no.1
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• pp.129-143
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• 2009

In South Korea, Mine industries were encouraged to obtain the natural resource from 1960 to 1980. However, the depletion of natural resource and decreasing price have been caused by the voluntary closure of non-economical mines and a cut of their production since 1990. Harmful wastewater containing such heavy metals as iron, aluminum, arsenic, and cadmium are being discharged from abandoned pits and waste stone and tailing dumping sites following the closure of mines. Therefore, the objective of this paper suggests a policy of mine hazard prevention(PMHP) and method that allows the combination of new spatial data and as well as collected data on resources for the sustainable mine reclamation and management using EGIS/MGIS technique to develop an integrated plan and management techniques.

• Journal of agricultural medicine and community health
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• v.41 no.2
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• pp.63-74
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• 2016

Objectives: We surveyed the awareness and current status of using fumigant carbon disulfide for exterminate Curculio sikkimensis among chestnut farmers in Chungnam Province to suggest directions for health education and public relations. Methods: We designed questionnaires to evaluate recognition of fumigant carbon disulfide. We conducted a questionnaire survey to assess recognition and recognition level of fumigant carbon disulfide by the study variables. Results: The recognition status for fumigant carbon disulfide was 74.5%, but the recognition level was low (know well 27.5%). The path of recognition was 45.1% and 15.7% for neighbor and rural technology center, respectively. The recognition status for warning label of fumigant carbon disulfide was 52.9%. Recognition for warning label of fumigant carbon disulfide was tended to increase with high educational attainment, bigger owning land area. Recognition on the content of warning label were 29.4%, 27.5%, 21.6%, and 21.6% for inflammability, toxicity, hazard, and explosiveness, respectively. Using personal protection equipment was tended to increase with the high status of awareness on fumigant carbon disulfide. Conclusions: Health education programs for using fumigant carbon disulfide are needed for chestnut farmers. In addition, publicity information activities about prevention and protection of carbon disulfide poisoning are needed for high risk farmers.

• Journal of the korean academy of Pediatric Dentistry
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• v.44 no.3
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• pp.317-326
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• 2017

The aim of this study was to investigate the survival and success rates of autotransplanted maxillary canine at the artificially formed recipient socket and evaluate the factors that influence survival and success rates. A total of 28 children who had 37 impacted canines were reviewed over the mean observation time of 25.1 months. Tooth mobility, pathologic root resorption, vertical bone loss, periapical lesion and anklyosis of donor tooth were investigated clinically and radiographically. The survival rate was 100%. The success rate was 64.9%, because 13 teeth were evaluated as unsuccessful. Significant parameter in determining the success rate of autotransplantation was enlarged follicle size of donor tooth according to Cox proportional hazard regression model. The results provide information necessary for clinician to make a better treatment decision about autotransplantation at the artificially formed recipient socket.

• Molecules and Cells
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• v.25 no.2
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• pp.272-278
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• 2008

The carbon-ion beam (CIB) generated by the heavy-ion medical accelerator in Chiba (HIMAC) was targeted to 7-day-old rice. Physiological parameters such as growth, and gene expression profiles were examined immediately after CIB irradiation. Dose-dependent growth suppression was seen three days post-irradiation (PI), and all the irradiated plants died by 15 days PI. Microarray (Agilent rice 22K) analysis of the plants immediately after irradiation (iai) revealed effects on gene expression at 270 Gy; 353 genes were up-regulated and 87 down-regulated. Exactly the same set of genes was affected at 90 Gy. Among the highly induced genes were genes involved in information storage and processing, cellular processes and signaling, and metabolism. RT-PCR analysis confirmed the microarray data.

• International Journal of Highway Engineering
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• v.14 no.6
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• pp.103-110
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• 2012

PURPOSES : In Korea, over 70 percent of the land consists of mountainous and rolling area. Thus, tunnels continue its upward trend as road network are extended. In these circumstances, the importance of tunnel has been increased nowadays and then its safety investigation and research should be performed. This study is focus on confirming and improving the safety of tunnel. On tunnel hood, sunglare effect can irritate driver's behavior instantly and this can result in incident. METHODS : The study of this phenomenon is rarely conducted in domestic and foreign papers, so there is no proper measure for this. This study analyzes the driving environment of the effect of sunglare effect on tunnel hood. RESULTS : Traffic accidents stem from complex set of factors. This study build the Traffic Accident Prediction Models to find out the effect of sunglare effect on tunnel's hood. The independent variables are traffic volume, geometric design of road, length of tunnel and road side environment. Using these variables, this model estimates accident frequency on tunnel hood by Poisson regression model and Negative binomial regression model. Although Poisson regression model have more proper goodness of fit than Negative binomial regression model, Poisson regression model has overdipersion problem. So the Negative binomial regression model is used in this analysis. CONCLUSIONS : Consequently, the model shows that sunglare effect can play a role in driving safety on tunnel hood. As a result, the information of sunglare effect should be noticed ahead of tunnel hood so this can prevent drivers from being in hazard situation.

• Journal of Korean Society of Rural Planning
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• v.11 no.2 s.27
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• pp.9-19
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• 2005

The purpose of this study is to analyze the potential soil loss and hazard zone by the Revised Universal Soil Loss Equation(RUSLE) for preservation and management of land resources which is the base of ecosystem, and to grasp the relationship between RUSLE factors in the Nakdong River Basin. All thematic maps used in RUSLE are constructed through GIS and spatial analysis method derived from digital topographic maps, detailed soil maps, land-cover maps, and mean annual precipitation of 30 years collected respectively from National Geographic Information Institute, National Institute of Agricultural Science and Technology, and Ministry of Environment. The slope length of LS-factor that takes much times by the study area's wideness was calculated automatically through AML(Arc Macro Language) program developed by Van Remortel et al.(2001, 2003). The results are as follows; First, according to the soil loss estimation by the RUSLE, it shows that approximately 82% of the study area have relatively lower possibility of soil loss which is the 1 ton/ha in annual soil loss. While, 9.4% ($2,228km^2$) needed intensive and continuous management for soil loss. Because the amount of their annual soil loss was greater than 10 ton/ha that is optimum level suggested by Morgan(1995). For these areas, the author believe that a new approach which can minimize environmental impacts from soil loss through improvement of cultivation process and buffer forest zone should be applied. Second, according to the relationship between the RUSLE factors, topographical(LS-factor) and cover management(C-factor) conditions have a lot of influence on soil loss in case of the Nakdong River Basin. However, because of RUSLE factor's influence that affect to soil loss might be different based on the variety of spatial hierarchy and extent, it is necessary to analyze and evaluate factor's relationship in terms of spatial hierarchy and extent through field observations and further studies.

• Genomics & Informatics
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• v.8 no.1
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• pp.9-18
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• 2010

Integrins are transmembrane receptor proteins that mediate cell-cell adhesion and cell-extracellular matrix (ECM) adhesion. The deregulation of cell-ECM adhesion and the abnormal expression of beta1 (${\beta}1$) integrins (ITGB1s) are involved in tumor development and metastasis. In the liver, the expression of integrins and ECM proteins can be a cause of hepatocellular carcinoma (HCC) development. We performed direct DNA sequencing of 24 individuals, and identified 23 sequence variants of ITGB1 polymorphisms. Among these 23 variants, 7 common variants were selected based on frequencies and linkage disequilibrium, and then genotyped in a larger-scale group of subjects (n=1,103). The genetic associations of ITGB1 polymorphisms with the clearance of HBV and HCC outcome of HBV patients were analyzed using logistic regression models and Cox relative hazard models. Although there was no significant association observed between the polymorphisms and the HCC outcome of HBV patients, the second most common haplotype (ITGB1 haplotype-2 [C-C-C-C-T-C-T]) was putatively associated with HBV clearance (OR=0.75, p=0.008 and $P^{corr}=0.05$). The minor allele frequency (MAF) of ITGB1 haplotype -2 of the spontaneously recovered (SR) group was significantly higher than that of the chronic carrier group (CC) (freq. = 0.248 vs. 0.199). The information derived from this study could be valuable for understanding the genetic factors involved in the clearance of HBV.