• 한국생물물리학회:학술대회논문집
• /
• 한국생물물리학회 2003년도 정기총회 및 학술발표회
• /
• pp.72-72
• /
• 2003

The PAS factor, whose gene has been cloned from V vulnifcus, is a protein secretion factor. Although the role of the PAS factor in Vibrio is still unknown, it may be involved with the bacterial protein secretion. The PAS factor is a 76 amino acid polypeptide, and its expression in E. coli cells makes the host cell membrane leaky, resulting in the excretion of periplasmic proteins into the culture medium. Highly expressed PAS factor is harmful to the cell, this may be due to a disruption of the membrane structure or function.

• 한국철도학회:학술대회논문집
• /
• 한국철도학회 2003년도 추계학술대회 논문집(III)
• /
• pp.617-622
• /
• 2003

Light Flickering of the lamp(fluorescent lamp) with voltage fluctuation operates as an factor harmful to train passengers which is subjective to them. Recently, international flickering standard(IEC61000-3-3) are applied all over the world. However, there are not any study preparing for regulation about light flickering inside running train. In this study, the Flicker phenomenon is investigated from several references and also how the flickermeter is configured and defined. Flicker evaluation using it are studied.

• 한국안전학회지
• /
• 제31권4호
• /
• pp.126-135
• /
• 2016

The purpose of this study is to develop risk assessment techniques and institutional analysis of domestic and international, the management techniques that can efficiently manage the harmful factor of the laboratory and to present the institutional measures that can be efficiently implemented. Due to a variety of adverse factors of laboratory, accidents of laboratory of various forms have occurred, but there is no risk assessment system in order to manage this effectively. So, we investigated this domestic existing risk assessment methods and the outside of the risk assessment system, and also analyzed accidents of domestic laboratory that occurred in 2014. In addition, we targeted the 24 laboratories in 21 universities to investigate the management of harmful factors of the laboratory and performed applying test for 12 domestic laboratories. Existing risk evaluation system, such as PMS, SMS, off-site impact assessment, since the industrial site is the subject, is a difficult problem to be directly applied to the laboratory of the research institute. So, we implemented management status and harmful factors survey and classified the research and development activities based on this data. Finally we developed "pre-hazards risk analysis method" to create each of the safety management measures. In addition, research activities personnel conducted voluntarily risk assessment, which is shared by institutions and government. It is presented the institutional system for safety management of laboratory. Its result, pre-hazards risk analysis method and institutionalization scheme will be able to achieve laboratory accident prevention system.

• 동의신경정신과학회지
• /
• 제19권1호
• /
• pp.71-81
• /
• 2008

Objective: Obesity threatens not only the problem of beauty but also health. Furthermore, it could be harmful a chronic disease to increase mortality rate. A purpose of this study is to show a effect of obesity control as developing a herbal medicine, Gyeongshingangjeehwan16 (GGEx16), in order to control obesity that is a harmful factor for healthy. Method : In order to prove the effect of GGEx16, BMI, fat distribution, fat control and fitness score which are closely related with obesity are considered as variables. Each variable is measured, for statistical analysis, using measurement implement of InBody 3.0 which applied a theory of bioimpedence analysis. Result and Conclusion : As a result of statistical analysis for four variables, it was improved that there are the improved effect for obesity because GGEx16 is statistically meaningful better than prior to taking.

• Journal of Microbiology and Biotechnology
• /
• 제31권10호
• /
• pp.1420-1429
• /
• 2021

The safety of the probiotic strain Q180, which exerts postprandial lipid-lowering effects, was bioinformatically and phenotypically evaluated. The genome of strain Q180 was completely sequenced, and single circular chromosome of 3,197,263 bp without any plasmid was generated. Phylogenetic and related analyses using16S rRNA gene and whole-genome sequences revealed that strain Q180 is a member of Lactiplantibacillus (Lp., formerly Lactobacillus) plantarum. Antimicrobial resistance (AMR) genes were bioinformatically analyzed using all Lp. plantarum genomes available in GenBank, which showed that AMR genes are present differently depending on Lp. plantarum strains. Bioinformatic analysis demonstrated that some mobile genetic elements such as prophages and insertion sequences were identified in the genome of strain Q180, but because they did not contain harmful genes such as AMR genes and virulence factor (VF)- and toxin-related genes, it was suggested that there is no transferability of harmful genes. The minimum inhibition concentrations of seven tested antibiotics suggested by the European Food Safety Authority guidelines were slightly lower than or equal to the microbiological cut-off values for Lp. plantarum. Strain Q180 did not show hemolytic and gelatinase activities and biogenic amine-producing ability. Taken together, this study demonstrated the safety of strain Q180 in terms of absence of AMR genes and VF- and toxin-related genes as a probiotic strain.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1996년도 하계학술대회 논문집 A
• /
• pp.324-327
• /
• 1996

This paper presents the adoption of PWM converter to enhance input power factor in inverter arc welder. By using PWM converter in inverter arc welder, the disadvantages of bridge diode converter such as low input power factor is improved, new NCT(Noise Cut Transformer) is designed to reduce noise which has harmful effect in switching component, half bridge PWM inverter is adopted to reduce cost in inverter arc welder.

• Biomolecules & Therapeutics
• /
• 제5권3호
• /
• pp.316-322
• /
• 1997

CJ-50001 is a recombinant granulocyte-colony stimulating factor (rG-CSF) synthesized by recombi-nant DNA technology using E. coli as an expression system. The general pharmacological properties of CJ-50001 were evaluated in mice, rats, dogs and isolated guinea pig ileum. The doses are 100, 300 and 1, 0007g/kg, i.v. for mice and rats, 1, 10 and 100$\mu$g/kg, 1.v. for dogs and 1 and 10$\mu$g/ml for isolated guinea pig ileum. Intravenous administration of CJ-50001 at this dose range did not affect general behavior, central nervous system, smooth muscles, gastrointestinal system, cardiovascular and respiratory system and water and electro-lytes excretion. In summary, CJ-50001 had no harmful pharmacological erect in these studies even up to the 200-fold expected clinical dose, 2507g/man.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1998년도 하계학술대회 논문집 A
• /
• pp.293-295
• /
• 1998

Linear Induction Motor is driven by inverter for speed control. Inverter contains many harmonics that was generated when the circuits is switching for a energy conversion. This harmonics is injurious, and harmful on the operational efficiency of motors. In this paper, it is certified the efficiency and power factor of LIMs and inverters in consideration with harmonics.

• 보건교육건강증진학회지
• /
• 제19권3호
• /
• pp.73-85
• /
• 2002

This study was conducted to examine community residents' knowledge level and related factor on electronic wave in order to provide basic data for development of education and publicity program. 2,000 people, who lived in five big cities and five small and medium cities, were selected ad subjects of this study. The data were collected from May 1, 200 I to August 31, 2001. The results of this study are as follows. According to the average knowledge level of harmful affect of electronic wave on health in general characteristics, female was higher(37.40 ± 5.24 points) than male; ‘forties’ was highest(37.77 ± 5.69 points); ‘married spouse’ was high(36.84 ± 5.59 points); ‘living in small-ta-medium city’ was high(36.84 ± 5.32 points). ‘university graduate’ was highest(37.41 ± 5.32 points) in education level, ‘middle class’ was high(36.61 ± 4.96 points) in economic status, ‘professional technician’ was higher(36.68 ± 6.55 points) than other occupations in occupational type. According to the knowledge level of harmful affect of electronic wave on health in health condition by self-judgment, ‘good health condition’ was highest(36.77 ± 4.99 points). In the case of the knowledge level of those who visited medical institutions for last one year, ‘never visited’ was highest(37.19 ± 5.02 points). In the kind of medical institutions, ‘those who visited general hospital’ was highest(36.58 ± 5.63 points). In the way of knowledge obtainments of electronic wave through education and publicity media, ‘school education’ was highest(37.55 ± 5.19 points). According to the score of awareness level of disease incidence related to electronic wave, allergy and erethism was highest(57.8 points on the basis of 100 points). It appeared in order of leukemia, skin disease or skin cancer, dementia, various cancers, cataract, and brain tumor. The variables which significantly influenced knowledge level of harm of electronic wave were knowledge obtainments of electronic wave, age, economic status, daily TV watching period, sex, period of daily cellular phone use, period of working with computer, and daily VTR watching period. The knowledge of community residents concerning harmful affect of electronic wave on health is needed because people's opportunity of exposing to electronic wave is increasing. Especially, it is the demands of the times to provide information on knowledge of each equipment which generate electronic wave. The government, the product manufacturing companies, related social organizations, and education institutions must make efforts to develop the education program which is needed to make people have right knowledge and attitude.

• 한국콘텐츠학회논문지
• /
• 제18권11호
• /
• pp.540-549
• /
• 2018

본 연구는 대구 경북지역에서 근무하는 치과위생사 238명을 대상으로 자기기입식 설문을 통하여 근무유형별 치과재료에 대한 유해전달 실태를 파악하기위해 병원 유형별 유해인자 노출시간 및 근무환경특성 차이를 비교하고 물질안전보건자료(MSDS) 인지정도의 차이를 조사하였다. 연구 결과 병원 유형별 유해인자 노출시간을 비교한 결과 병원의 경우 화학물질에서 발생하는 분진유발에 노출되는 시간이 가장 길었고, 레진충전, 소독제 접촉 순으로 나타났다. 치과재료에 대한 물질안전보건자료(MSDS)를 인지하고 있는지에 대한 문항에 대하여 '인지한다'고 답한 대상자는 병원근로자는 37명(29.4%), 14명(12.5%)로 나타났으며(p<0.001), 치과재료를 사용하기 전 MSDS를 읽어본 경험이 있는 근로자는 병원근로자는 18명(14.3%), 의원근로자는 6명(5.4%)으로 조사되었다. 사용하는 치과재료의 물질안전보건자료(MSDS)를 비치한다고 응답한 대상자는 병원근로자의 경우 의원근로자에 비해 2.39배 물질안전보건자료(MSDS)를 비치하는 경우가 많았다. 이에 병원 유형별 특성에 맞게 화학물질의 건강상의 유해성에 대해 인지하고 안전보건교육을 지속적으로 실시함으로써 MSDS 정보에 대한 올바른 인식확립으로 근무환경이 개선되어져야 할 것이며, 치과재료의 제품에 사용설명서 및 MSDS 화학물질 정보제공 관리가 강화하여 전략적 접근 및 근로자의 알 권리를 보장할 수 있는 제도의 필요성을 제안한다.