• Journal of the Korean Applied Science and Technology
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• v.39 no.5
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• pp.614-622
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• 2022

This study attempted to investigate the effect of manufacturing a formulation with lavender extract and applying it to damaged hair. The experimental material was prepared by adding 0 g, 3 g 6 g, and 9 g of lavender extract to the perm base agent. The prepared formulation was applied to four damaged hair samples and compared and analyzed. As a measurement method for the effect on damaged hair, tensile strength, absorbance using methylene blue, and gloss were measured. Statistical analysis was conducted for the reliability of the research results. The tensile strength measurement results showed that the tensile strength of the sample applied with a formulation containing 6 g and 9 g at 8 levels increased, affecting damaged hair. As a result of absorbance analysis using methylene blue, it was found that the absorbance of all samples applied by adding extracts decreased, affecting damaged hair. The gloss measurement results showed that the addition of 9 g affected the damaged hair. In conclusion, it can be seen that lavender extract affects damaged hair, so it is considered to have an effect of improving Damage hair.

• Journal of the Korean Applied Science and Technology
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• v.41 no.1
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• pp.36-45
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• 2024

This study was to investigate the effect of manufacturing an avocado oil-added formulation and applying it to damaged hair. The experimental materials were prepared by adding avocado oil contents of 0 g, 3 g, 6 g, and 9 g to the perm base agent. It was applied to 4 damaged hair samples with the prepared formulation for comparative analysis. Tensile strength, absorbance using methylene blue, and gloss were measured as measurement methods for the effect on damaged hair. Statistical analysis was performed for the reliability of the research results. As a result of the tensile strength measurement, it was found that the tensile strength of the sample applied with the formulation containing 6 g and 9 g to the sample increased, affecting damaged hair. As a result of the absorbance analysis using methylene blue, it was found that the absorbance of all samples applied by adding oil decreased, affecting damaged hair. The gloss measurement result was found to affect damaged hair when 6 g and 9 g were added. The conclusion is that avocado oil affects damaged hair, so it is thought that it will have an effect of improving hair.

• Korean Journal of Oriental Medicine
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• v.16 no.3
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• pp.167-173
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• 2010

Objects : Glycine max Merr. (black bean), Triticum aestivum L. (wheat) and Oryza sativa L. (rice bran) have been widely used for treatment of relaxion of smooth muscle, gastrointestinal hemorrhage and alopecia in Korean Traditional Medicine. In this research, we examined the effect of the extracts, obtained from EtOH extracts of 3 kinds of traditional plants, on hair growing activity of the DP6 and C3H10T1 cell and physical properties. Materials and Methods : On the basis of previous studies, three traditional plants were selected and we extracted them with ethanol. We evaluated their hairy dermal papillar cell proliferation activity and mouse mesenchymal stem cell in vitro model. Also, 3 herbal extracts were added to the normal shampoo formulation in ranges of 0.1% and we validated tensile properties and physical changes using aged hair. In this research, we compared the tensile strength, shine and color appearance between the hair (general formulation) and the hair after applying shampoo with natural extracts. To analyze the luster and color image, we use the SAMBA hardware and software made by Bossa Nova Technologies. Results : In the comparative test for tensile characteristic between the hair treated general formulation(control) and the hair applying special formulation including 3 kinds of extracts, tensile distance and energy of the latter are larger than control on average. The shine and color appearance were also increased after using shampoo including natural extracts(shine : 10.9%, color appearance: 24.12%). We observed the enhancement of hair growth activity in the DP6 and C3H10T1 cell. Especially black bean extracts had the most powerful effect in the dermal papillar cell proliferation. Conclusion : These experiments suggest that extracts of Glycine max Merr. (black bean), Triticum aestivum L. (wheat) and Oryza sativa L. (rice bran) stimulate the hair growth activity and can improve physical activities of aged hair. Shampoo product, which contains 3 kinds of natural extracts, would be used for the treatment for aged hair.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.1
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• pp.1-10
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• 2009

Objectives : To investigate the effects of DL-HGF to hair growth activity in mouse, various kinds of ethosome and liposome formulations entrapped DL-HGF were produced and this study was carried out. Methods : The B16/BL6 mice were classified into five groups: vehicle control (Con) group, Et-1-applied group, Et-2-applied group, LP-1-applied group, LP-2-applied group. Active hair growth (anagen) was induced in the back skin by application of a waxosin mixture with subsequent depilation and the activity of hair growth was measured by macroscopic observation and histology. Results : In vehicle control group, there was no hair growth activity during experiment period. In Et-1-applied group, the rate of hair growth was about 100%, LP-1-applied group and Et-2-applied group showed 70-80% and 40-50% of hair growth rates, respectively. The rate of hair growth of LP-2-applied group was lower than other applied groups (20-30%). In H/E staining, Numerous hair folicles and hair shafts were observed in Et-1-applied group and other groups showed lower level of hair folicles and hair shafts formation than Et-1-applied group, Conclusion : Et-1 formulation showed highest hair growth activity than other ethosome and liposome formulations entrapped DL-HGF.

• Journal of the Korean Applied Science and Technology
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• v.38 no.4
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• pp.986-993
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• 2021

This study was aimed to investigate the improvement effects of kelp extract on the damaged hair by manufacturing hair quality improving formulation adding kelp extract and applying that in the damaged hair. With respect to the study materials, the formulation was manufactured with different strengths of kelp extract including 0, 2, 4, and 6 grams, adding perm base material. The manufactured formulation was applied to the decolored sample hair of Level 8 and its effects were measured and compared before and after its application. Tensile strength, absorbance using methylene blue, and gloss were measured as the tools to show the improvement effects of hair quality. To check the reliability of the results, statistical analysis was performed. Tensile strength showed to be increased in the Level 8 samples applied by the formulations containing 4- and 6-gram strength. Absorbance using methylene blue showed to be decreased in all the samples after the application, based on the absorbance results before and after the application. No difference was found in all the samples on the gloss. In conclusion, this study revealed that kelp extract could improve the damaged hair. Further studies are required to check the improvement effects on the damaged hair with multiple types of extracts and study methods.

• Journal of the Korean Applied Science and Technology
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• v.38 no.4
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• pp.1176-1182
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• 2021

In this study, the emulsion stability of henna, a natural hair dye, according to the content of cetyl alcohol, one of the emulsification stabilizers, was analyzed, and the content of cetyl alcohol showing the most stable emulsification was confirmed. To analyze the emulsion stability, differences in particle size, particle shape, viscosity, and color after dyeing were compared according to the content of cetyl alcohol. As a result of dynamic light scattering (DLS) zeta analysis, cetyl alcohol 3% showed the highest zeta potential value of 115.9 mV, and the particle size distribution was henna in which a cream-type hair dye containing 3% cetyl alcohol was dispersed in distilled water. The width of the particle size distribution was narrow compared to. As a result of viscometer analysis, the viscosity increased as the content of cetyl alcohol increased. As a result of measuring the henna pH of the cream formulation, it was measured in a pH range suitable for the scalp. As a result, emulsion stability increases as the content of cetyl alcohol increases in henna cream formulations for hair dye.

• Journal of the Korean Applied Science and Technology
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• v.39 no.3
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• pp.471-478
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• 2022

This study attempted to find out the improvement effect the improvement effect of Babassu oil on damaged hair by damaged hair by applying a hair-improving formulation with Babassu oil to damaged hair after manufacturing. As the experimental raw material, the contents of babassu oil were changed to 0 g, 3 g 6 g, and 9 g and added to the perm base agent. The prepared formulation was applied to 8 levels of bleached sample hair. Each sample and damaged hair were measured and compared and analyzed. As for the measurement method, tensile strength, absorbance using methylene blue, and gloss were measured to know the effect of improving damage hair Statistical analysis was conducted for the reliability of the research results. As a result of the research, it was found that the tensile strength was higher than that of the damaged hair in all samples applied by adding babassu oil. As a result of absorbance analysis using methylene blue, it was found that absorbance was decreased in all samples compared to damaged hair. As a result of the gloss measurement, it was found that the gloss was increased in all samples compared to the damaged hair. In conclusion, it was found that babassu oil had an improvement effect on damaged hair.

• The Journal of the Convergence on Culture Technology
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• v.4 no.3
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• pp.253-259
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• 2018

Astrigent persimmon fruit resources have been used traditionally to treat different systemic diseases and acclaimed for various biological activities including hair growth. This study investigates the hair restoration efficacy of astrigent persimmon fruit extracts on genetically predisposed to balding pattern Black mice model. Water extract of astrigent persimmon fruit(10 mg/mouse/day) with standardized vehicle formulation, only vehicle and positive control minoxidil (2%) were applied daily until completion of two full hair growth generations. The changing pattern of hair growth were observed through two hair growth generations of C57BL/6 Black mice. The hair existing area and hair length was increased significantly (P > 0.001) in astrigent persimmon fruit treated mice than vehicle-treated control mice. Furthermore, histological assessment revealed that the number of hair follicles did not remarkably increase after astrigent persimmon fruit treatment in compare to control mice. Thus, our data revealed that the topical application of astrigent persimmon fruit may promote hair growth in nude mice by extend the hair existing area and increase hair length which is an indicator of prolong anagen phase.

• Biomolecules & Therapeutics
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• v.19 no.2
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• pp.231-236
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• 2011

The aim of this study was to investigate the effect of charge carrier lipid on the skin penetration, retention, and hair growth of topically applied finasteride-containing liposomes. Finasteride-containing liposomes were prepared by traditional thin film hydration method using Phospholipon$^{(R)}$ 85 G and cholesterol with or without charge carrier lipid (1,2 dimyristoyl-sn-glycero-3-phosphate or 1,2-dioleoyl-trimethylammonium-propane for anionic and cationic charge, respectively). Freshly prepared finasteride-containing liposome suspension was applied on the hairless mouse skin, and skin penetration and retention were measured using Keshary-Chien diffusion cell. Non-liposomal formulation (ethanol 10% solution containing 0.5 mg/ml of FNS) was also used as a control. The amount of finasteride in the diffusion cell and mouse skin was measured by HPLC. The hair growth was evaluated using depilated male C57BL/6N mice. Mean particle size of all finasteride-containing liposomes was less than a micron, and polydispersity index revealed size homogeneity. Skin penetration and retention studies showed that significantly less amount of finasteride was penetrated when applied as anionic liposome while more amount of the drug was retained. Specifically, in liposome prepared with 10% anionic charge carrier lipid, penetration was 12.99 ${\mu}g/cm^2$ while retention was 79.23 ${\mu}g/cm^2$ after 24 h of application. In hair growth study, finasteride-containing anionic liposomes showed moderate efficacy, but the efficacy was not found when applied as cationic liposomes. In conclusion, topical application of finasteride using anionic liposome formulation appears to be useful option for the treatment of androgenetic alopecia to avoid systemic side effects of the drug.

• Journal of the Korean Applied Science and Technology
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• v.39 no.2
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• pp.294-302
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• 2022

This study attempted to investigate the effect of improving damaged hair by preparing a hair improving agent with basil oil and applying it to damaged hair. An experimental material was added to a perm base agent containing 0 g, 3 g, 6 g, 9 g of basil oil to prepare the preparation. It was applied to sample hair bleached at 8 levels with the prepared formulation. Each sample and damaged hair were measured and analyzed. The measurement method measured tensile strength, absorbance and gloss using methylene blue to determine the effect of improving maternal quality. Statistical analysis was conducted on the reliability of the study results. Studies have shown that all samples with basil oil have higher tensile strength than damaged hair. As a result of the absorbance analysis using methylene blue, it was found that the absorbance was lower than that of damaged hair in all samples. Gloss measurement showed that all samples showed increased luster compared to damaged hair. In conclusion, basil oil was found to improve damaged hair. In the future, research on various types of oil and research methods is needed.