• Proceedings of the PSK Conference
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• 2003.04a
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• pp.205.2-206
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• 2003

This experiment was designed to evaluate the immune responses after treatment of diabetes by using water extract of traditional herbal drugs on the splenocytes and peritoneal macrophages in vivo. We found two herbal materials of the hypoglycemic agents based on inhibitory activity of ${\alpha}$-glucosidase. These potential herbal drugs which remarkably inhibited ${\alpha}$-glucosidase in STZ-induced diabetic mices (STZ 150 mg/kg, i.p.) were Mori radicis Cortex(MRC, 2.32 mg/mouse) and Cudraniae radicis Cortex (CRC, 2.24mg/mouse). (omitted)

• Toxicological Research
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• v.29 no.4
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• pp.257-261
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• 2013

${\alpha}$-Curcumene is one of the physiologically active components of Curcuma zedoaria, which is believed to perform anti-tumor activities, the mechanisms of which are poorly understood. In the present study, we investigated the mechanism of the apoptotic effect of ${\alpha}$-curcumene on the growth of human overian cancer, SiHa cells. Upon treatment with ${\alpha}$-curcumene, cell viability of SiHa cells was inhibited > 73% for 48 h incubation. ${\alpha}$-Curcumene treatment showed a characteristic nucleosomal DNA fragmentation pattern and the percentage of sub-diploid cells was increased in a concentration-dependent manner, hallmark features of apoptosis. Mitochondrial cytochrome c activation and an in vitro caspase-3 activity assay demonstrated that the activation of caspases accompanies the apoptotic effect of ${\alpha}$-curcumene, which mediates cell death. These results suggest that the apoptotic effect of ${\alpha}$-curcumene on SiHa cells may converge caspase-3 activation through the release of mitochondrial cytochrome c.

• Journal of Industrial Technology
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• v.31 no.A
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• pp.59-62
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• 2011

The demineralizing effect of chelating agents(Maleic acid solution, EDTA salts solutions; disodium-, trisodium- and tetrasodium-EDTA) on hydroxyapatite(HA) for the root canal dentin treatment was investigated. Dissolution of Ca from HA was increased with increasing immersion time in chelating solutions. Among the EDTA salts solutions, tetrasodium-EDTA was least effective in dissolving Ca out from HA, and trisodium-EDTA was the most effective. Trisodium-EDTA solutionmight be more effective in removing the smear layer compared to tetrasodium-EDTA solution.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.50 no.spc1
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• pp.37-40
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• 2005

In order to find out better cultivation practices in mid-mountainous area to produce high quality rice, an experiment involving seven nitrogen fertilizer rates and three varieties was carried out, during past two years$(2003\~2004)$. There was an interaction effect on palatability of milled rice between nitrogen fertilizer rate and variety. The palatability of Junambyeo grown by the treatment of nitrogen fertilizer yale wasn't different across the rates significantly, but Hwayongbyeo's palatability grown by 0 kg/ha nitrogen treatment was better than 50, 70,170 kg/ha, and Sangmibyeo's palatability grown by 70 kg/ha nitrogen treatment was better than 90, 110, 140, 170 kg/ha. Amylose content of milled rice was showed without a significant difference between nitrogen fertilizer rate, but in between variety, the amylose content of Sangmibyeo was lower than Hwayongbyeo's, also Hwayongbyeo's amylose content was lower than Junambyeo's. Protein content of milled rice was showed an interaction effect between nitrogen fertilizer rate and variety. The protein content of Hwayongbyeo and Junambyeo grown by the treatment of nitrogen fertilizer rate wasn't different across the fertilizer yale significantly, but Sangmibyeo's protein content grown by 0 kg/ha nitrogen treatment was lower than the rest of treatments, and it's protein content grown by 50, 70, 90 and 110 kg/ha nitrogen treatment was lower than 140 and 170 kg/ha. Bead rice yield of milled rice grown by lower nitrogen fertilizer rate, was lower than that grown by higher nitrogen fertilizer rate. In a conclusion gathering all above the results to produce high quality rice in Mid-mountainous area, the applicative nitrogen fertilizer rate was 70 kg per ha for Sangmibyeo, 110 kg/ha for Hwayongbyeo and 140 kg/ha for Junambyeo, in considering with head rice yield, palatability, amylose${\cdot}$protein content and productivity.

• The Journal of Pediatrics of Korean Medicine
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• v.20 no.3
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• pp.11-22
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• 2006

Objectives : Molluscum Contagiosum is a contagious disease most often seen in children. It is caused by molluscum contagiosum virus(MCV-1,2). The purpose of this study is to report three cases of Molluscum Contagiosum children treated by oriental medicine. Methods : The subjects are in regard to children diagnosed as Molluscum Contagiosum. We treated three children with herbal medicine(Gwakhyangjeonggisangamibang). Results : After treatment, the symptoms(papule on the whole body and pruritus) of Molluscum Contagiosum were improved. Two children of them were cured completely and the one child still appealed a little itching. But, the one child had atopic dermatitis, and suffered from itching primarily, so after treatment the itching sign decreased rather than before an attack of Molluscum Contagiosum. Conclusions : This study shows that oriental medicine can be an effective treatment for Molluscum Contagiosum. And the further study is needed with more cases and longer duration.

• Journal of Haehwa Medicine
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• v.9 no.1
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• pp.113-120
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• 2000

This study was carried out to investigate the relation between the Onbyung and the skin disease, and classify the medical treatment by some categories. The results were as follows ; 1. Onbyung reduces the Eun(陰) by the fever and the skin disease results from the deficiency of the Eun and blood. 2. We can grasp the depth of the disease and the damage of the Jung Gi(正氣) by the observation of the every condition on the skin disease. 3. Medical treatment 1. Hae Phyo Bub(解表法) Using the method of the perspiration, we take care of the preservation of the sap. 2. Cheong Gi Bub(淸氣法) of the using Gypsum and Tong Ha Bub(通下法) of the using Dae Whang(大黃). A. Cheong Gi Bub(淸氣法) When the Sa(邪) stay the Gi area(氣分), we use the radiational material or the Wha Sub(化濕) material with Gypsum. B. Tong Ha Bub(通下法) We reduce the evil fever by the Ha Bub(下法). 3. Cheong Yul Hae Dog Bub(淸熱解毒法) and Ja Eum Bub(滋陰法) 4. Wha Sub Bub(化濕法) This treatment reduce the fever by eliminating the urine or the sweat.

• Korean Journal of Veterinary Research
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• v.12 no.1
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• pp.77-84
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• 1972

Throughout the studies the following experimental results were obtained and summarized. 1. Treatment of MVE virus with acetone, Tween-ether and Tween-ether-protamine sulphate caused an eight to 16 fold increase in HA activity. 2. Treatment with acetone and Tween-ether resulted in a four fold increase in CF activity. Treatment with Tween-ether-protamine sulphate decreased the activity. 3. The crude virus showed a complete loss of infectivity after treatment with Tween-ether, but three log unit was, decreased with acetone treatment. 4. The HA activity of treated and crude virus was disappeared after heating at $37^{\circ}C$ for 60 minutes but CF activity was increased. 5. Tween-ether or acetone treatment equally applicable to the preparation of haemagglutinin for HI test. 6. Zonal centrifugation of crude virus in a linear ten to 60 percent sucrose gradient showed two peaks of CF activity, and one of high buoy ant density part accompanied by HA activity and infectivity and the other of lower density part. Acetone treatment brought a decrease of the high density CF activity but not affected the second peak of low density found with crude virus, and resulted in increased HA activity and decreased infectivity. The peaks of HA, CF and infectivity after acetone treatment were not clearly separated. Tween-ether treatment caused a loss of the peak of CF activity found in the area of high density with crude virus, but the peak in the area of low density was not affected. This peak of CF activity was separated from noninfectious HA activity. The HA and CF activities were considered to be contributed by different parts of the varion.

• Korean Journal of Soil Science and Fertilizer
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• v.32 no.2
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• pp.155-163
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• 1999

Nutrient balance during rice cultivation in the paddy of a local area under the environmental protection for drinking water supply was investigated. To compare nutrient balance in the paddy soil applied with different types of fertilization, 7 treatments were selected as followings : Recommended level of chemical fertilizers(R), Conventional fertilization(CF), Fresh cow manure(FCM), Cow manure compost(CMC), Straw compost+reduced chemical fertilizer(SCF), Fresh straw+recommended level of fertilizers(FSC), and no fertilization as control(C). Here, FCM, CMC and SCF were applied at the same level of total nitrogen as recommended in R. Rice yield was the highest in the recommendation(R) and fresh cow manure (FCM) treatments with $6,730kg\;ha^{-1}$(index 100), and followed by SCF (index 98), FSC (index 98), CMC(index 94), and CF(index 94). But statistically significant difference was not recognized among treatments except the control. Nitrogen infiltration loss was high in the simple chemical fertilizer treatments with $63kg\;ha^{-1}$ in CF and $58kg\;ha^{-1}$ in R during rice cultivation, respectively. Nitrogen infiltration loss was decreased below half level of chemical fertilizer treatments with cow manure treatments ($23kg\;ha^{-1}$ in FCM and $27kg\;ha^{-1}$ in CMC) and with reducing chemical fertilizer treatment by adding straw compost ($25kg\;ha^{-1}$). Phosphate was not leached during rice cultivation in paddy soil of a fluvial deposit type, in which oxidation horizon was developed broadly under around 15 cm depth of surface soil. Phosphate balance (A-B) was closed to 0 in all treatments except cow manure treatment (CMC), in which it was $+30kg\;ha^{-1}$ and show the possibility of over accumulation of phosphate by continuously replicated application of cow manure compost. Potassium balance was negative value in all but straw recycling treatment (FSC). It means that potassium was continuously supplied from soil minerals, uptaken by plants or eluted out of soil. In conclusion, by substituting inorganic fertilizer for organic fertilizer or reducing application rate of chemical fertilizer through mixing organic fertilizer, it would be possible to achieve the same rice yield as in the recommendation treatment and to decrease nutrient leaching below half level in rice paddy soil.

• Korean Journal of Organic Agriculture
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• v.21 no.2
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• pp.207-217
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• 2013

This study was conducted to estimate organic Hanwoo carrying capacity when whole crop wheat and triticale as winter forage crops were grown on different applying sources (no fertilizer, organic fertilizer or cattle slurry), and mixed sowing in combination with hairy vetch and forage pea at the level of 50% cattle slurry application during the period of 2009~2011. The experimental plots were consisted of 5 treatments. Each treatment was triplicates and allocated in the randomized complete block design. For whole crop wheat, annual mean dry matter (DM) yield was significantly (P<0.05) higher for fertilizer application treatments than for no fertilizer treatment, and crude protein (CP) yield was significantly (P<0.05) higher for forage pea and hairy vetch-mixed sowing treatments than for no fertilizer and organic ferilizer treatments. Mean CP, total digestible nutrients (TDN) and relative feed value (RFV) contents of legumes-mixed sowing treatments was significantly (P<0.05) higher than those of other treatments. As diets replaced with 70% whole crop wheat were provided for 450kg of Hanwoo heifers, legumes-mixed sowing treatments could raise more heifers than organic fertilizer and no fertilizer treatments. For triticale, annual mean DM, CP and TDN yields were significantly (P<0.05) higher for fertilizer application treatments than for no fertilizer treatment, and CP content of legumes-mixed sowing and cattle slurry application treatments was significantly (P<0.05) higher than that of other treatments. When 450kg of Hanwoo heifers were fed on diets replaced with 70% triticale, it was estimated that legumes-mixed sowing treatments at the level of 50% cattle slurry application could rear average 3.3~3.4 heads/ha/year, which was significantly (P<0.05) higher than no fertilizer treatment (2.5 heads/ha/year). It was indicated that DM yields of whole crop wheat and triticale were much more effective in cattle slurry application than organic fertilizer, and Legumes-mixed sowing at the level of 50% cattle slurry application rather than whole crop wheat or triticale alone increased yields per unit area and nutritional value such as CP content. In conclusion, it is conceived that whole crop wheat or triticale produced in the manner above can be used instead of grains imported as dietary protein sources in the organic Hanwoo feeding regimen.

• 한국초전도학회:학술대회논문집
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• v.16
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• pp.6-6
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• 2006