• Journal of Oriental Neuropsychiatry
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• v.21 no.2
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• pp.87-101
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• 2010

Objectives : The aim of this experiment was to investigate the influences of Autonomic Nervous System and EEG by conducting Reinforcement-Reduction(補瀉) acupuncture stimulation to compare the changes in acupoints on the body before and after treatment of acupuncture at Xingjian(LR2) being referred as Fire-point(火穴) and Ququan(LR8) being referred as Water-point(水穴) of Yin Liver Meridian(足厥陰肝經). Methods : This study was carried out on 30 healthy female volunteers in their 20's. There were four tests conducted throughout and the period for each test was between 2 to 5days. HRV and EEG were measured for 5 minutes before acupuncture stimulation was conducted on LR2-Reinforcement, LR2-Reduction, LR8-Reinforcement and LR8-Reduction at random. During the 20 minutes of acupuncture treatment, same subjects were measured simultaneously to observe any significant changes in acupoints. Again, the same subjects were measured for 5 minutes after removing the acupuncture in order to perform a comparative analysis. Results : The measurement of HRV showed that LF, LFnorm and LF/HF ratio increased significantly(p<0.05) while HF, HF norm decreased significantly in case of LR2-Reinforcement & LR8-Reduction. Both LR2-Reduction and LR8-Reinforcement induced a significant increase in HFnorm. EEG measurement indicated low $\alpha$ wave decreased and high $\beta$ wave increased significantly at LR2-Reinforcement during post-acupuncture period compared with acupuncture stimulation period. Both LR2-Reduction and LR8-Reinforcement developed significantly low $\alpha$ wave and high $\alpha$ wave. High $\beta$ wave increased significantly at LR8-Reduction during the acupuncture stimulation in comparison with pre-acupuncture period. Conclusions : The manipulation of acupuncture stimulation at LR2-Reinforcement and LR8-Reduction enhanced the activity of sympathetic nerves and the state of arousal while that of para sympathetic nerves declined. On the other hand, LR2-Reduction and LR8-Reinforcement developed the levels of para sympathetic nerves and relaxation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.3
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• pp.525-532
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• 2010

Dypepsia is the most common gastrointestinal disease and mainly occurs by stress or food. According to the cause of dyspepsia, the clinical characteristics and the curative process are different in patients. The purpose of this study is to compare acute dyspepsia patients depending on food factor and stress factor. For this study, we analyzed the cause, and the symptoms of 59 acute dyspepsia patients and divided them into two groups: one group is 27 acute dyspepsia patient group caused by stress factor (stress factor group). The other group is 32 acute dyspepsia patient group caused by food factor (food factor group). In addition, we carried out HRV test and compared HRV index between two groups. There was no significant difference in past illness involved in gastrointestinal tract diseases between two groups. There were big differences in the frequency of chest discomfort, thurst, lack of appetite, and exhaustion after meals between two groups. There were many changes of tongue fur in food factor group. But there were many changes of tongue body in stress factor group. The pulse pattern is mostly wiry in stress factor group. But, The pulse pattern is mostly slippery in food factor group. HF, TP were significantly lower than food factor group in stress factor group, it means autonomic nerve system was more suppressd in stress factor group than food factor group. Food factor group improved sooner than stress factor group. This study presented the clinically different characteristics (past medical history, symptoms, tongue diagnosis, pulse pattern, curative process) of acute dyspepsia depending on food factor and stress factor. Thus, it provides the necessity of oriental medical diagnosis and treatment called pattern identification for acute dyspepsia.

• Journal of People, Plants, and Environment
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• v.24 no.5
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• pp.545-550
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• 2021

Background and objective: With increasing land use intensity in urban areas, apartment buildings have been recognized as a typical type of urban residence. In this study, the impacts of different views through a window on health-related responses were investigated using psychological and physiological parameters. Methods: Photos of three different types of views taken on low (2-12 m), middle (28-35 m), and high (over 54 m) floors of dense apartment building areas were used as visual stimuli. Twenty-two healthy adults participated in the indoor experiment. Semantic differential methods and profile of mood states were used as psychological tools. Autonomic nervous activity was evaluated using blood pressures, pulse rate and heart rate variability (HRV). Results: Analytic data showed different characteristics of psychological and physiological outcomes in three different apartment views. In the analysis of psychological parameters, significantly negative responses to the views on middle floors were found in the subscales of tension-anxiety and anger-hostility, compared to low floors. Significantly positive scores in the subscale of vigor were found on low floors with abundance of vegetation and high floors with a view of the sky. A significantly increased value of HF was found on low floors (2,294.96 ± 169.79), compared to the middle(1,553.45 ± 84.66) and high (1,523.02 ± 70.49) floors. Despite the high scores in openness and vigor, high floor views showed significantly higher LF/HF values (1.83 ± 0.09), the indicator of the sympathetic nervous system, than low (1.30 ± 0.07) and middle floor views (1.34 ± 0.06), which might be related to the unconscious fear of heights. Conclusion: Views from different heights in an apartment building can affect the psychological states of residents. Green space through the window may have a positive health outcome by reducing physiological stress.

• The Journal of Internal Korean Medicine
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• v.41 no.5
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• pp.838-847
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• 2020

Objectives: The aim of this study was to investigate the clinical characteristics of patients with Burning Mouth Syndrome (BMS) due to hyposalivation (HS). Methods: We reviewed the clinical records of 39 BMS patients who visited the Department of Digestive Diseases of Kyunghee Korean Medicine Hospital from March 1st, 2020 to July 31st, 2020. The subjects were classified according to the presence or absence of hyposalivation and both groups were compared for the proportion of coated tongue, heart rate variability (HRV), Ryodoraku, and the numeral rating scale (NRS) score of tongue pain results. Results: The BMS with Hyposalivation (HS group) and the BMS without Hyposalivation (Non-HS group) showed a significant difference in the proportion of coated tongue and the NRS score for tongue pain. The NRS score was significantly higher in the Non-HS group and the proportion of coated tongue was lower. However, no significant differences were noted in several HRV parameters between the two groups. The most frequent accompanying symptoms were xerostomia and dyspepsia. Conclusions: The results of this study suggest that hyposalivation might be one of the main causes of tongue pain, the key complaint in BMS patients. Sympathetic/parasympathetic imbalance might not be a main contribution of hyposalivation in BMS. Instead, factors such as the number of medications taken seem to correlate with hyposalivation in BMS. This results could be useful in the management of BMS patients with hyposalivation in clinical practice.

• The Journal of Korean Medicine
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• v.32 no.5
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• pp.50-65
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• 2011

Objectives: Moxibustion has been used for various post-stroke symptoms and has also been known to have effect on peripheral blood flow. This study investigated the effect of moxibustion on radial artery blood flow by Doppler ultrasound and on heart rate variability in post-stroke hemiplegia patients. Methods: Moxibustion was applied on the points of LI4, TE3, TE5 and LI11 on the affected side, and blood flow of the radial artery was measured using the Minimax-Doppler-K device. Blood flow velocity and pulsation index were analyzed before, during, and after moxibustion. Simultaneously LF, HF, and LF/HF as variables for HRV were measured by FM-150. Results: The mean value of blood flow velocity in all patients (n=23) showed significant increase between before and after moxibustion, but there was no significant difference in pulsation index and LF, HF, LF/HF ratio between before and after moxibustion. In Yin (n=9) and Yang (n=14) groups, both showed significant increase of blood flow velocity between before and after moxibustion, but there was no significant difference in pulsation index and LF, HF, LF/HF ratio between before and after moxibustion. In Deficiency (n=14) and Fullness (n=9) groups, only the Deficiency group showed significant increase of blood flow velocity between before and after moxibustion, while the Fullness group showed no significant difference in blood flow velocity between before and after moxibustion, and also there was no significant difference in pulsation index and LF, HF, LF/HF ratio between before and after moxibustion. Conclusions: This study suggests that moxibustion on LI4, TE3, TE5 and LI11 on the affected side of stroke patients increase the peripheral blood flow in the affected arm, which was most remarkable in those with Yin and Deficiency pattern.

• Journal of Acupuncture Research
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• v.29 no.4
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• pp.25-34
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• 2012

Objectives : This study was conducted to investigate the effects of fixed-intensity and varied-intensity electroacupuncture in pain and sensory threshold concerning parameters visual analogue scale(VAS), brief pain inventory(BPI) and quantitative sensory testing(QST), among chronic tension headache patients. Methods : Thirty patients with chronic tension headache were randomly assigned to three groups and received different kinds of electroacupuncture at $ST_{36}$ and $ST_{37}$. Group A received fixed-intensity electroacupuncture(fixed-EA), group B received varied-intensity electroacupuncture (varied-EA), and group C received only acupuncture treatment without electrical stimulation as a control group. The intervention was given three times per week, and continued in two weeks. All the experiments were conducted blindly. Results : Fixed-EA group showed a significant decrease of VAS and BPI compared to the baseline measurement, while both varied-EA and control group did not. Of the parameters of QST, subtraction of heat pain threshold(HPT) and cold pain threshold(CPT) slightly increased in all groups, but this was not significant. Conclusions : These results suggest that fixed-EA reduce pain and improve quality of life in patients with chronic tension headache and that acupuncture may regulate patient's pain sensitivity through changing sensory threshold.

• Journal of the Korean Society of School Health
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• v.29 no.2
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• pp.116-122
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• 2016

Purpose: This study compared the effects of two six-week school-based intervention programs - a health promotion program using a school forest and a traditional school health promotion program (TSHPP) - on physical and mental health among elementary school students. Methods: A total of 73 students participated in the study: 21 students in the 6-week school forest program conducted in a rural area and 52 students in the 6-week TSHPP conducted in an urban area. Children's health promotion behavior, depression and hyperactivity were measured using a self-report questionnaire. To assess children's physical health, body mass index (BMI), body fat percentage, and heart rate variability (HRV) were used. Results: Overall, both intervention programs improved participants' physical and mental health. Both programs significantly decreased the body fat percentage; this effect was more prominent in the TSHPP group. Only the TSHPP significantly decreased the participants' BMI after the intervention. The school forest group showed significantly improved relaxation and diminished hyperactivity; the TSHPP group showed significantly improved health promoting behavior and social relationship after the intervention. Comparing the two groups'post-pre difference scores, the two groups significantly differed only in social relationship. Both group showed significantly improved depression after the intervention. Conclusion: These findings support the effectiveness of these 6-week school-based health promotion programs in improving physical and mental health among school-aged children.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.8
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• pp.3925-3932
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• 2013

Emotion is closely related to the life of human, so has effect on many parts such as concentration, learning ability, etc. and makes to have different behavior patterns. The purpose of this paper is to extract important features based on physiological signals to recognize negative emotion. In this paper, after acquisition of electrocardiography(ECG), electroencephalography(EEG), skin temperature(SKT) and galvanic skin response(GSR) measurements based on physiological signals, we designed an accurate and fast algorithm using combination of linear discriminant analysis(LDA) and genetic algorithm(GA), then we selected important features. As a result, the accuracy of the algorithm is up to 96.4% and selected features are Mean, root mean square successive difference(RMSSD), NN intervals differing more than 50ms(NN50) of heart rate variability(HRV), ${\sigma}$ and ${\alpha}$ frequency power of EEG from frontal region, ${\alpha}$, ${\beta}$, and ${\gamma}$ frequency power of EEG from central region, and mean and standard deviation of SKT. Therefore, the features play an important role to recognize negative emotion.

• Journal of Oriental Neuropsychiatry
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• v.31 no.2
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• pp.63-76
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• 2020

Objectives: The purpose of this study was to verify the clinical effects of herbal medicines on patients with depressive disorder. Methods: A prospective observational study on patients with depressive disorder was conducted. The patients were treated with herbal medicines for eight weeks. The Korean Hamilton Depression Rating Scale (K-HDRS) was evaluated as the primary outcome and the Korean Beck's Depression Inventory (K-BDI), Instrument on Pattern Identification for Depression, Korean Symptom Checklist-95 (KSCL-95), Insomnia Severity Index (ISI), Korean State-Trait Anxiety Inventory (STAI-K), Korean State-Trait Anger Expression Inventory (STAXI-K), EuroQol five-dimensional Questionnaire (EQ-5D), Minnesota Multiphasic Personality Inventory-2 (MMPI-2), Heart Rate Variability (HRV) were measured as the secondary outcome. Adverse events were assessed for safety. Results: A total of 35 participants were observed for 12 weeks. The K-HDRS improved significantly in four, eight, and 12 weeks and the K-BDI showed significant differences in four, and eight weeks. There were no significant improvements in other evaluation scales. Gyejibongnyeong-hwan was the most frequently and continuously prescribed, showing significant improvements of K-HDRS after eight weeks of treatment. Conclusions: In our observational study, herbal medicine was effective for relieving the depression of patients with depressive disorder and Gyejibongnyeong-hwan showed the most significant effectiveness.

• Journal of Sasang Constitutional Medicine
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• v.23 no.4
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• pp.487-502
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• 2011

1. Objective This study was performed to research the biological change of forest healing according to Sasang constitution. 2. Methods Forty seven applicants are involved in this study. They were classified into three groups(Soyangin, Taeeumin, Soeumin) by QSCC II. And then they participated in forest healing program from March 26 to March 27 in 2011. We performed before and after experiment, including vital sign, electroencephalography(EEG), heart rate variability(HRV), complete blood cell count(CBC), biochemical test(BC), and stress hormones. 3. Results Men had the relaxative effect of tension. While, the group of women and Soyangin was more sensitive to sudden environmental change than the group of men or other constitutions. The tension of women and soyangin's group increased after the forest healing program. Soeumin group showed reduced diastolic blood pressure after the forest healing program. 3. Conclusions Forest healing program has shown better efficacy in relaxation in men than women, in lowering diastolic blood pressure in Soeumin group than other constitutional groups. However a single positive result within this study should be carefully interpreted.