• Title/Summary/Keyword: HOX

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A Probabilistic Approach to the Assessment of Phylogenetic Conservation in Mammalian Hox Gene Clusters

  • Stojanovic, Nikola;Dewar, Ken
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.118-123
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    • 2005
  • With the increasing availability of mammalian genome sequences it became possible to use large scale phylogenetic analysis in order to locate potentially functional regions. In this paper we describe a new probabilistic method for the characterization of phylogenetic conservation in mammalian DNA sequences. We have used this method for the analysis of Hox gene clusters, based on the alignment of 6 species, and we constructed a map of for indicating short and long conserved fragments and their positions with respect to the known locations of Hox genes and other elements, sometimes showing surprising layouts.

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Measurement of Tropospheric HOx(OH, $HO_2$) Radicals Radicals by Laser-Induced Fluorescence Technique (레이저 유도 형광법을 이용한 대류권 HOx(OH, $HO_2$) 라디칼 분석 기술 개발)

  • 민경은;이호재;박종호;최종호;이미혜
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2002.11a
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    • pp.292-293
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    • 2002
  • 대기 중에서 HOx(OH, H $O_2$) 라디칼은 가장 중요한 산화제로서 광화학 반응의 핵심적 역할을 한다. 이러한 OH 라디칼의 정확한 농도를 측정하기 위한 여러 가지 시도가 있었으나, 그 존재량이 적고 수명이 짧기 때문에 측정에 많은 어려움이 있다. 간접적인 측정에 근거한 모델링과 계산적인 이론 값에 의하면 대류권에서의 전 지구적 평균 OH 라디칼의 농도는 대략 $10^{6}$molecules $cm^{-3}$이고, H $O_2$ 라디칼의 농도는 $10^{8}$molecules $cm^{-3}$정도로 추정된다. (중략)

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Expression Pattern of labial-like Gene of the Earthworm, Perionyx excavatus (지렁이 labial-like유전자의 발현 양상에 관한 연구)

  • 조성진;이명식;허소영;이종애;박범준;조현주;박순철
    • The Korean Journal of Soil Zoology
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    • v.7 no.1_2
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    • pp.29-34
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    • 2002
  • Hox genes are a family of regulatory gene encoding transcription factor that primarily play a crucial role during development. Several indications suggest their involvement in the control of cell growth and regenration. RT-PCR and souther blot analysis revealed that labial-like gene was increasingly expressed along a spatial gradient in the anterior region of intact worm. During head and tail regeneration, labial-like gene was expressed only in the head region of regenerating body pieces, suggesting that the gene is involved in the anteroposterior patterning in earth-worm. This result could give us information on the significance of Hox genes and the relationship between Hox genes during regeneration.

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Differential Expression of Hox and Notch Genes in Larval and Adult Stages of Echinococcus granulosus

  • Dezaki, Ebrahim Saedi;Yaghoobi, Mohammad Mehdi;Taheri, Elham;Almani, Pooya Ghaseminejad;Tohidi, Farideh;Gottstein, Bruno;Harandi, Majid Fasihi
    • Parasites, Hosts and Diseases
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    • v.54 no.5
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    • pp.653-658
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    • 2016
  • This investigation aimed to evaluate the differential expression of HoxB7 and notch genes in different developmental stages of Echinococcus granulosus sensu stricto. The expression of HoxB7 gene was observed at all developmental stages. Nevertheless, significant fold differences in the expression level was documented in the juvenile worm with 3 or more proglottids, the germinal layer from infected sheep, and the adult worm from an experimentally infected dog. The notch gene was expressed at all developmental stages of E. granulosus; however, the fold difference was significantly increased at the microcysts in monophasic culture medium and the germinal layer of infected sheep in comparison with other stages. The findings demonstrated that the 2 aforementioned genes evaluated in the present study were differentially expressed at different developmental stages of the parasite and may contribute to some important biological processes of E. granulosus.

A Synthesis of Tungsten Complexes with Oxine, Aniline or Pyridine in Organic Solvent (有機溶媒中에서 옥신, 아닐린 및 피라딘을 포함하는 텅스텐錯物의 合成)

  • Doo Won Park;Tae Sub O
    • Journal of the Korean Chemical Society
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    • v.19 no.6
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    • pp.414-419
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    • 1975
  • The insoluble tungsten complexes with 8-hydroxy quinoline (oxine=Hox), aniline (A), and pyridine(Py) in several organic solvents have been synthesized. Using the different solvents with oxine, two different complexes have been synthesized in dichloromethane and dimethylformamide(DMF), respectively. Only one kind of complex has been synthesized with aniline in dichloromethane and with pyridine in acetone. The complexes may be formulated as $WCl_2(Hox)_2,\;[WO_2(Ox_2)],\;[WCl_3A_3],\;and\;[WO_2ClPy]$ by the results of elemental analysis, infrared spectral data, and thermogravimetric analysis.

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