• 제목/요약/키워드: HKL

검색결과 22건 처리시간 0.016초

Magnolol 및 Honokiol의 항생제와의 병용 효과 (Antibacterial Activity of Magnolol and Honokiol in Combination with Antibiotics)

  • 정경수;이수나;김영호;배기환
    • 생약학회지
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    • 제31권4호
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    • pp.407-411
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    • 2000
  • Antibacterial activities of magnolol (MGL) and honokiol (HKL) in combination with four representative antibiotics-amoxicillin (AMPC), oxytetracyclin (OTC), gentamicin (GM) and chloramphenicol (CAP)-were evaluated against four bacterial strains. When tested by disk-plate method, five out of eight combinations such as HKL-AMPC, HKL-CAP, MGL- AMPC, MGL-OTC, and MGL-CAP showed additive to synergistic interaction against gram- negative bacterium Salmonella typhimureum. Of these, MGL-AMPC combination turned out to be antagonistic against Sarcina lutea and Bacillus thurungiensis. Against these two grain-positive bacteria, only HKL-GM combination showed additivity to synergism. All the other combinations showed no interactions. Despite these results, however, no synergism was observed in checkerboard titration assay.

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X-Ray Triple Crystal Diffraction Spectrometer의 제작과 그 응용 (X-Ray Triple Crystal Diffraction Spectrometer and Its Applications)

  • 박영한;염효영;윤형근;민석기;박용주
    • 한국결정학회지
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    • 제8권1호
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    • pp.20-25
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    • 1997
  • 고분해도의 X-선 산란을 위해 두 실험 방법이 개발됐다. 그 방법들은 (1) 2-결정 회절 스펙트로메터 (DCD)설치와 (2) 3-결정 회절 스펙트로메터 (TCD) 설치였다. Si(511)-시료(hkl)의 DCD배열로 Si(333), Si(004), GaAs(004)의 rocking curve를 그렸다. 또한 단일체 단색 평행기와 $K_{\alpha1}$ 선택기를 포함하는 Si(111)-Si(111)-Si(511)-sample(hkl)의 TCD배열로 Si(333), Si(004) 그리고 GaAs(004)의 rocking curve를 그렸다. DCD와 TCD에 의한 rocking curve의 FWHM의 차이가 논의됐다. DCD에 의한 $In_{0.037}Ga_{0.0963}As/GaAs$의 (004) 및 (115) 반사 토포그라프가 행해졌다.

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Change of Crystalline Properties of Poly(ethylene-co-vinyl acetate) according to the Microstructures

  • Choi, Sung-Seen;Chung, Yu Yeon
    • Elastomers and Composites
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    • 제56권2호
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    • pp.92-99
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    • 2021
  • Microstructure-dependent changes in the crystalline properties of poly(ethylene-co-vinyl acetate) (EVA) was investigated using various EVAs at different VA contents via X-ray diffraction (XRD). The parameters analyzed herein were percentage crystallinity (Xc), interplanar crystal spacing (dhkl), crystal stack size (Dhkl), and the number of crystal plane piles (Nhkl). The Xcs of [110] and [200] crystals were 21.0-4.1 and 6.7-1.4%, respectively, and they decreased by approximately 2.3 and 0.7% for every mol% of the VA content, respectively. The Xc ratios of the [110] and [200] crystals were approximately 3. The d110s and d200s values were 0.41-0.42 and 0.37-0.38 nm, respectively. The D110s and D200s values were 9.56 -21.92 and 7.00-16.42 nm, respectively. The dhkls increased with an increase in the VA content, whereas the Dhkls decreased. The N110s and N200s were 22.7-51.3 and 18.3-43.2, respectively, and they decreased by increasing the VA content. EVA with the same VA content showed different crystalline properties as per the suppliers, and some EVAs deviated from the average trends. This could be explained by the difference in their microstructures such as the sizes and distribution uniformity of the ethylene sequences in EVA chains.

Identification and Phylogenetic Analysis of Long Terminal Repeat Elements of the Human Endogenous Retrovirus K Family (HERV-K) from a Human Brain cDNA Library

  • Kim, Heui-Soo;Lee, Young-Choon
    • Animal cells and systems
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    • 제5권2호
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    • pp.133-137
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    • 2001
  • Long terminal repeats (LTRs) of the human endogenous retrovirus K family (HERV-K) have been found to be coexpressed with sequences of genes closely located nearby. We examined transcribed HERV-K LTR elements in human brain tissue. Using cDNA synthesized from mRNA of the human brain, we performed PCR amplification and identified ten HERV-K LTR elements. These LTR elements showed a high degree of sequence similarity (92.4-99.7%) with the human-specific LTR elements. A phylogenetic tree obtained by the neighbor-joining method revealed that HERV-K LTR elements could be divided into two groups through evolutionary divergence. Some HERV-K LTR elements (HKL-B7, HKL-B8, HKL-B10) belonging to the group II from human brain cDNA were closely related to the human-specific HERV-K LTR elements. Our data suggest that HERV-K LTR element are active in the human brain; they could conceivably play a pathogenic role in human diseases such as psychosis.

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InterplanarA: 결정학적(結晶學的) 면간(面間) 각(角)의 계산(計算)을 위한 a Computer Program (InterplanarA: A Computer Program for the Calculation of the Crystallographic Interplanar Angles)

  • 서태원;강상욱;서일환
    • 한국결정학회지
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    • 제20권1호
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    • pp.15-18
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    • 2009
  • 실격자(real lattice)에서 이차원적인 (hkl)면의 총 집합이 역격자(reciprocal lattice)에서 한 개의점(點)으로 나타내어지며 원점에서 이 역격자점을 이은 vector의 방향은 (hkl)면의 방향이다. 따라서 두 역격자 vectors간의 각도가 결정학적 두 면간의 각도이므로 이들 각도들을 계산해보면 역격자의 개념을 이해하는데 도움이 된다. 이 논문에서는 6개의 실격자 상수 a, b, c, $\alpha$, $\beta$, $\gamma$를 사용하여 두 결정학적 면 ($h_1k_1l_1$)과 ($h_2k_2l_2$)간의 각도를 계산하는 한 computer program 'InterplanarA'를 소개하였다.

Physico-mechanical, AC-conductivity and microstructural properties of FeCl3 doped HPMC polymer films

  • Prakash, Y.;Somashekarappa, H.;Manjunath, A.;Mahadevaiah, Mahadevaiah;Somashekar, R.
    • Advances in materials Research
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    • 제2권1호
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    • pp.37-49
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    • 2013
  • The transition metal salt doped solid polymer electrolyte [TSPE] were prepared with HPMC as a host polymer. The virgin and doped films were prepared by solution-casting method and investigated using wide angle X-ray scattering method. Micro structural parameters like lattice strain (g%), stacking/twin faults, the average number of unit cells counted in a direction perpendicular to the Bragg's plane (hkl) spacing of (hkl) planes dhkl, crystallite size Ds, distortion width, standard deviation were determined by whole pattern powder fitting (WPPF) method, which is an extension of single order method. It is found that the crystallite size decreases with the increase in the content of $FeCl_3$. This decrease is due to increase in localized breaking of polymer network which also accounts for the amorphous nature of the material. The filler inorganic salt $FeCl_3$ acts as plasticizer. FTIR study also confirms and justifies the interaction between the polymer and in-organic salt in the matrix. Physical properties like mechanical stability and Ac conductivity in these films are in conformity with the X-ray results.

Application of Vector Moving Preisach Model to Longitudinal Thin Film Media

  • S. C. Seol;T. Kang;K. H. Shin;Lee, T. D.;Park, G. S.
    • Journal of Magnetics
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    • 제2권3호
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    • pp.101-104
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    • 1997
  • Vector Moving Preisach model has been applied to the unoriented Co-based alloy thin film media. In the model, the out-of plane easy axis distribution of the particles was derived directly from the texture coefficient phkl obtained from XRD analysis, which corresponds to the fraction of the grains that have the {hkl} plane lying parallel to in-plane direction. The model was validated, by its prediction of a variety of responses, including major loop, minor loop, and the angular dependence of coercivities.

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일라이트 폴리타입: 그 특성과 단층 활동연대 결정에의 활용 (Illite Polytypes: The Characteristics and the Application to the Fault Age Determination)

  • 송윤구
    • 자원환경지질
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    • 제45권2호
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    • pp.181-188
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    • 2012
  • 일라이트에서 적층방식을 달리하여 나타나는 폴리타입은 대부분 1M과 $2M_1$이며, 적층 Disordering에 따른 $1M_d$ 또한 흔히 관찰된다. 본 해설에서는 일라이트의 폴리타입을 구분하고 정량적으로 해석할 수 있는 광물학적 이론적 근거와 방법을 소개하고, 소규모 열수환경에 준하는 단층대 내 생성시기 및 조건을 달리하는 일라이트 폴리타입 혼합물에의 적용을 통한 단층 활동 및 재활동연대 결정에의 활용 가능성을 검토하였다. 단층연대해석의 정확도와 신빙도를 높이기 위해서는 단층암 대상시료 내 일라이트 폴리타입의 생성환경에 대한 정보, 동정 및 광물학적 특성에 대한 규명이 이루어져야 한다. 또한 WILDFIRE(C)시뮬레이션을 이용한 정량분석에서, $1M_d$ 폴리타입의 Disordering 정도 및 I/S 광물의 팽창도에 기인한 (hkl) 회절선들의 Broadening 효과 등 일라이트 폴리타입 정량분석법의 오차요인을 최소화시키는 하기 방법을 고려해야 할 것이다.

Human Lysozyme 유전자의 화학적 합성과 Saccharomyces cerevisiae 에서의 발현 (Chemical Synthesis of a Human Lysozyme Gene and Expression in Saccharomyces cerervisiae)

  • 김기운;이승철;황용일
    • 한국미생물·생명공학회지
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    • 제23권2호
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    • pp.138-144
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    • 1995
  • The cDNA, encoding human lysozyme (HLY) which was isolated from a human placenta cDNA library, has been well characterized (Yoshimura et al., 1988). Based on the communication, we have prepared an artificial HLY gene from chemically synthesized 38-oligomer with high codon usage in Saccharomyces cerevisiae. For directing the synthesis and secretion of HLY in S. cerevisiae, an expression vector, pHKl was constructed by inserting the HLY gene, containing a synthetic HLY secretion signal sequence, between the yeast GAP promoter and PH05 terminator. From a lysoplate assay, we have confirmed an yeast transformant harboring a pHK1 which makes a clearing zone on the overlayed Micrococcus luteus. This result means a chemically synthesized HLY gene which was normally expressed and secreted in yeast.

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