• 제목/요약/키워드: HIV-positive

검색결과 112건 처리시간 0.021초

Ten years of experience in the prevention of mother-to-child human immunodeficiency virus transmission in a university teaching hospital

  • Park, Jung-Weon;Yang, Tae-Whan;Kim, Yun-Kyung;Choi, Byung-Min;Kim, Hai-Joong;Park, Dae-Won
    • Clinical and Experimental Pediatrics
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    • 제57권3호
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    • pp.117-124
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    • 2014
  • Purpose: Administration of antiretroviral drugs to mothers and infants significantly decreases mother-to-child human immunodeficiency virus (HIV) transmission; cesarean sections and discouraging breastfeeding further decreases this risk. The present study confirmed the HIV status of babies born to mothers infected with HIV and describes the characteristics of babies and mothers who received preventive treatment. Methods: This study retrospectively analyzed medical records of nine infants and their mothers positive for HIV who gave birth at Korea University Ansan Hospital, between June 1, 2003, and May 31, 2013. Maternal parameters, including HIV diagnosis date, CD4+ count, and HIV ribonucleic acid (RNA) copy number, were analyzed. Infant growth and development, HIV RNA copy number, and HIV antigen/antibody test results were analyzed. Results: Eight HIV-positive mothers delivered nine babies; all the infants received antiretroviral therapy. Three (37.5%) and five mothers (62.5%) were administered single- and multidrug therapy, respectively. Intravenous zidovudine was administered to four infants (50%) at birth. Breastfeeding was discouraged for all the infants. All the infants were negative for HIV, although two were lost to follow-up. Third trimester maternal viral copy numbers were less than 1,000 copies/mL with a median CD4+ count of $325{\mu}L$ ($92-729{\mu}L$). Among the nine infants, two were preterm (22.2%) and three had low birth weights (33.3%). Conclusion: This study concludes that prophylactic antiretroviral therapy, scheduled cesarean section, and prohibition of breastfeeding considerably decrease mother-to-child HIV transmission. Because the number of infants infected via mother-to-child transmission may be increasing, studies in additional regions using more variables are necessary.

HIV감염자와 폐결핵환자 간의 스트레스지각과 삶의 질의 비교 (The Comparison of Perceived Stress, Quality of Life between Patients with HIV Positive and Patients with Pulmonary Tuberculosis)

  • 이상혁;고경봉;김준명;박성혁
    • 정신신체의학
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    • 제11권1호
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    • pp.15-24
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    • 2003
  • 본 연구의 목적은 HIV감염자, 폐결핵환자, 정상인간에 스트레스지각과 삶의 질을 비교하는데 있다. 스트레스 지각 및 정신병리는 각각 스트레스 반응 척도(Stress Response Inventory)와 간이정신진단검사(SCL-90-R)를, 삶의 질은 스미스클라인비참 삶의 질 척도(SmithKline Beecham Quality of Life Scale)를 이용하여 평가하였다. HIV감염자들이 폐결핵환자, 정상인들보다 스트레스반응 점수에 있어서는 긴장, 분노, 우울, 피로, 좌절 점수가 각각 유의하게 더 높았다. 정신병리에서는 HIV감염자들이 폐결핵환자, 정상인들보다 신체화, 우울, 불안, 적대감, 공포불안, 편집증, 정신증 하위척도 점수에서 각각 유의하게 더 높았다. 삶의 질의 비교에서는 HIV감염자군이 폐결핵환자군보다 삶의 질이 유의하게 더 낮았다. HIV감염자들은 연령이 낮을수록, 교육기간이 길수록 신체화, 강박증, 대인민감성, 공포불안, 편집증, 정신증 등 정신병리 점수가 더 높았다. 이상의 결과들은 HIV감염자들이 폐결핵환자들과 정상인들에 비해 스트레스지각이 더 높고 더 많은 정신병리를 가지고 있으며 삶의 질이 저하되어 있음을 시사한다.

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HIV 감염자의 삶에 관한 연구 (Life Experiences of Korean Men with HIV/AIDS)

  • 박영숙;오윤희
    • 여성건강간호학회지
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    • 제11권2호
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    • pp.110-119
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    • 2005
  • Purpose: The purpose of this study was to illuminate the life experiences of 10 Korean men with HIV. Method: This is qualitative research using a grounded theory methodology. Result: A core category - enduring under the yoke of HIV and 5 subcategories emerged: Accepting the fact of HIV infection unwillingly with shock, Conflict between the secret concealment and disclosure, Resisting social prejudice and discrimination, Change of the daily life and management of health, Remembering their past lives without HIV and reconstructing their own lives with HIV. Conclusion: The findings contributed to understanding the HIV/AIDS illness experiences among men with hetero & homo sexuality, and revealing the prejudice against HIV in Korean society. The results have very important implications for health care professionals working with HIV-positive men.

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HIV감염자와 폐결핵환자 간의 스트레스지각과 삶의 질의 비교 (The Comparison of Perceived Stress, Quality of Life between Patients with HIV Positive and Patients with Pulmonary Tuberculosis)

  • 이상혁;고경봉;김준명;박성혁
    • 정신신체의학
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    • 제10권2호
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    • pp.120-129
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    • 2002
  • 연구목적: 본 연구의 목적은 HIV감염자, 폐결핵환자, 정상인간에 스트레스지각과 삶의 질을 비교하는데 있다. 방법: 스트레스 지각 및 정신병리는 각각 스트레스 반응 척도 (Stress Response Inventory) 와 간이정신진단검사 (SCL-90-R)를, 삶의 철은 스미스클라인비챰 삶의 질 척도 (SmithKline Beecham Quality of Life Scale)를 이용하여 평가하였다. 결과: HIV감염자들이 폐결핵환자, 정상인들보다 스트레스반응 정수에 있어서는 긴장, 분노 우울, 피로, 좌절 점수가 각각 유의하게 더 높았다. 정신병리에서는 HIV감염자들이 폐결핵환자 정상인들보다 신체화, 우울, 불안, 적대감, 공포불안, 편집중, 정신증 하위척도 점수에서 각각 유의하게 더 높았다. 삶의 질의 비교에서는 HIV 감염자군이 폐결핵환자군보다 삶의 질이 유의하게 더 낮았다. 연령이 낮을수록, 교육기간이 길수록 신체화, 강박증, 대인민감성, 공포불안, 편집증, 정신증 등 정신병리 점수가 더 높았다. 결론: 이상의 결과들은 HIV감염자들이 폐결핵환자들과 정상인들에 비해 스트레스지각이 더 높고 더 많은 정신 병리를 가지고 있으며 삶의 질이 저하되어 있음을 시사한다.

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Biofilm-forming ability and adherence to poly-(methyl-methacrylate) acrylic resin materials of oral Candida albicans strains isolated from HIV positive subjects

  • Uzunoglu, Emel;Bicer, Arzu Zeynep Yildirim;Dolapci, Istar;Dogan, Arife
    • The Journal of Advanced Prosthodontics
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    • 제6권1호
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    • pp.30-34
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    • 2014
  • PURPOSE. This study evaluated the adhesion to acrylic resin specimens and biofilm formation capability of Candida albicans strains isolated from HIV positive subjects' oral rinse solutions. MATERIALS AND METHODS. The material tested was a heat-cured acrylic resin (Acron Duo). Using the adhesion and crystal violet assays, 14 oral Candida albicans isolated from HIV-positive subjects and 2 references Candida strains (C. albicans ATCC 90028 and C. albicans ATCC 90128) were compared for their biofilm production and adhesion properties to acrylic surfaces in vitro. RESULTS. There were no significant differences in adhesion (P=.52) and biofilm formation assays (P=.42) by statistical analysis with Mann-Whitney test. CONCLUSION. Denture stomatitis and increased prevalence of candidal carriage in HIV infected patients is unlikely to be related to the biofilm formation and adhesion abilities of C. albicans to acrylic resin materials.

HIV/AIDS 환자의 영적 안녕과 영적 요구도 조사 (A Research of the Spiritual Well-Being and Spiritual Needs of HIV/AIDS Patients)

  • 곽지현
    • Journal of Hospice and Palliative Care
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    • 제12권1호
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    • pp.14-19
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    • 2009
  • 목적: HIV/AIDS환자의 영적 안녕과 영적 요구 정도를 파악하여 간호실무 면에서 HIV/AIDS 환자의 영적 건강 사정과 영적 간호 중재 방안을 마련하는데 기초 자료를 제공하고자 본 연구를 시도하게 되었다. 방법: HIV/AIDS 환자의 영적 안녕과 영적 요구와의 관계를 파악하기 위한 관계성 조사연구(Correlation Survey Research)이며, 연구 대상은 20세에서 70세 사이의 HIV/ AIDS 환자 51명이다. 결과: 1. HIV/AIDS환자의 영적 안녕 점수는 평균 54.59점이었고, 영적 안녕의 하위 영역인 실존적 안녕은 27.78점, 종교적 안녕은 26.80점으로 모두 중 정도 이상으로 나타났다. 따라서 HIV/AIDS환자들은 자신의 영적인 안녕 상태에 대해 중 정도로 지각하고 있다고 볼 수 있으며, 종교적 안녕보다 실존적 안녕의 점수가 높게 나타났다. 2. HIV/AIDS환자의 영적 요구 점수는 평균 108.67점이고 영역별로는 사랑과 관심에 대한 요구가 37.80점, 의미와 목적을 갈망하는 요구가 42.35점, 용서받고 싶은 요구가 28.51점으로 의미와 목적을 갈망하는 요구, 사랑과 관심에 대한 요구, 용서받고 싶은 요구 순으로 높게 나타났다. 3. 영적 안녕과 영적 요구의 상관 관계에서 HIV/AIDS환자의 총 영적 안녕과 총 영적요구는 약한 순 상관관계를 나타냈다(r=0.344, P=0.013). 영적 안녕의 하위영역인 실존적 안녕과는 통계적으로 유의하지 않게 나타났으며, 종교적 안녕과는 순 상관관계를 보였다. 결론: HIV/AIDS환자의 영적 안녕과 영적 요구는 중 정도 수준 이상으로 나타났으며, 영적 안녕과 영적 요구간의 약한 순 상관관계를 나타냈다. HIV/AIDS환자들은 의미와 목적을 갈망하는 요구도가 높으므로 이에 대한 영적 간호를 제공하여 현재 위기 상태의 경험에서 삶의 의미와 목적을 찾도록 하여 실존적 영적 안녕 정도가 증진되도록 지지하고, 앞으로 대상자 수를 확대한 연구와 영적 안녕을 증진시키는 간호 중재에 대한 연구가 계속되어야 하리라고 사료된다.

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Detection of Enteropathogens in Human Immunodeficiency Virus and Non-Human Immunodeficiency Virus-Infected Children with Acute Diarrhea in an Indonesian Tertiary Hospital Using Multiplex Real-Time Polymerase Chain Reaction

  • Dewi Wulandari;Rivaldi Febrian;Pramita Gayatri Dwipoerwantoro;Nia Kurniati
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제27권2호
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    • pp.95-103
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    • 2024
  • Purpose: Diarrhea is one of the leading causes of mortality in children living in developing countries. The etiology of acute diarrhea in each healthcare center varies depending on place, time, and population. This study aimed to identify pathogen patterns in human immunodeficiency virus (HIV)-infected and non-HIV children suffering from acute diarrhea, using multiplex real time reverse transcriptase polymerase chain reaction (RT-PCR), in an Indonesian tertiary hospital. Methods: This cross-sectional study was conducted at Dr. Cipto Mangunkusumo National Hospital from March 2019 to April 2020. Results: The study showed that multiplex RT-PCR results were positive in 58.9% of the specimens, with more positive results in HIV-infected children than in non-HIV-infected children (70% vs. 54.7%). Altogether 72 enteropathogens were detected from all specimens. Enteropathogens in non-HIV children with acute diarrhea consisted of bacteria (70.6%) and viruses (29.4%) with a predominance of enteroaggregative Escherichia coli (25.4%), followed by Campylobacter spp. (11.8%), enteropathogenic E. coli (9.8%), Norovirus GII (7.8%), and Clostridium difficile (7.8%). Enteropathogens in HIV-infected children consisted of viruses (57.1%), bacteria (28.6%), and parasites (14.3%) comprising Norovirus GII (24%), Cryptosporidium spp. (14.3%), Campylobacter spp. (14.3%), Norovirus GI (14.3%), and Astrovirus (14.3%). Cryptosporidium spp. was the only parasite found in this study and was found only in HIV-infected children. In non-HIV children with acute diarrhea, most pathogens were invasive bacteria, while in HIV-infected children, more viral and parasite infections occurred, primarily caused by opportunistic pathogens. Conclusion: The pattern of enteropathogens can help clinicians determine further examinations and appropriate empirical antimicrobial therapy for the patient.

왜!왜! 내가 에이즈에 ···

  • 대한에이즈예방협회
    • 레드리본
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    • 통권68호
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    • pp.10-11
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    • 2006
  • HIV에 감염되었다는 것은 질병을 얻었다는 것 외에도 정신적 충격이 거의 동반된다. 그 이유는 에이즈 발견초기 병의 감염경로나 예방법이 알려지지 않은 상태에서 공포와 두려움으로 에이즈를 알렸기 때문이다. 25년이 지난 지금에도 HIV에 감염되지 않은 사람은 감염된 사람을 부정하고 낙인찍기를 서슴치 않고, 이런 이유로 감염된 사람들은 자신의 감염사실에 좌절하고 분노하기에 이른다. 그렇다면 HIV에 감염된 초기 감염인들은 자신의 감염사실을 어떻게 받아들이는 게 좋은지 포즈닷컴의 유용한 정보를 번역하여 게재하도록 한다. positive life 는 HIV 감염인들에게 유용한 정보를 매호 제공할 예정이다.

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Estimation of Seroconversion Dates of HIV by Imputation Based on Regression Models

  • Lee, Seungyeoun
    • Communications for Statistical Applications and Methods
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    • 제8권3호
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    • pp.815-822
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    • 2001
  • The aim of this study is to estimate the seroconversion date of the human immunodeficiency virus(HIV) infection for the HIV infected patients in Korea. Data are collected from two cohorts. The first cohort is a group of "seroprevalent" patients who were seropositive and AIDS-free at entry. The other is a group of "seroincident" patients who were initially seronegative but later converted to HIV antibody-positive. The seroconversion dates of the seroincident cohort are available while those of the seroprevalent cohort are not. Estimation of seroconversion date is important because it can be used to calculate the incubation period of AIDS which is defined as the elapsed time between the HIV infection and the development of AIDS. In this paper, a Weibull regression model Is fitted for the seroincident cohort using information about the elapsed time since seroconversion and the CD4$^{+}$ cell count.The seroconversion dates for the seroprevalent cohort are imputed on the basis of the marker of maturity of HIV infection percent of CD4$^{+}$cell count.unt.

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Seroprevalence of Toxoplasma gondii Infection among HIV/AIDS Patients in Eastern China

  • Shen, Guoqiang;Wang, Xiaoming;Sun, Hui;Gao, Yaying
    • Parasites, Hosts and Diseases
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    • 제54권1호
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    • pp.93-96
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    • 2016
  • Toxoplasmosis, a neglected tropical disease caused by the protozoan parasite Toxoplasma gondii, occurs throughout the world. Human T. gondii infection is asymptomatic in 80% of the population; however, the infection is life-threatening and causes substantial neurologic damage in immunocompromised patients such as HIV-infected persons. The major purpose of this study was to investigate the seroprevalence of T. gondii infection in subjects infected with HIV/AIDS in eastern China. Our findings showed 9.7% prevalence of anti-T. gondii IgG antibody in HIV/AIDS patients, which was higher than in intravenous drug users (2.2%) and healthy controls (4.7%), while no significant difference was observed in the seroprevalence of anti-Toxoplasma IgM antibody among all participants (P>0.05). Among all HIV/AIDS patients, 15 men (7.7%) and 10 women (15.9%) were positive for anti-T. gondii IgG antibody; however, no significant difference was detected in the seroprevalence of anti-Toxoplasma IgG antibody between males and females. The frequency of anti-Toxoplasma IgG antibody was 8.0%, 13.2%, 5.5%, and 0% in patients with normal immune function ($CD4^+$ T-lymphocyte count ${\geq}500cells/ml$), immunocompromised patients (cell count ${\geq}200$ and <500 cells/ml), severely immunocompromised patients (cell count ${\geq}50$ and <200 cells/ml), and advanced AIDS patients, respectively (cell count <50 cells/ml), while only 3 immunocompromised patients were positive for anti-T. gondii IgM antibody. The results indicate a high seroprevalence of T. gondii infection in HIV/AIDS patients in eastern China, and a preventive therapy for toxoplasmosis may be given to HIV/AIDS patients based on $CD4^+$ T lymphocyte count.