• Journal of Digital Contents Society
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• v.12 no.4
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• pp.585-592
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• 2011

Real Estate Auction Information System purposes on providing high quality information of auction customized to consumer's situation and preference. Especially, ever-changing real time information such as the number of hits and advanced analysis for expecting the winning bid are requiring of mobile information system based on context awareness. Therefore, this paper studies on Real Estate Auction Information System based on context awareness under a smart phone environment providing auction information such as consumer's current position, the number of hits to a specific real estate, and the number of bidder to anticipate the winning bid.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 1999.06a
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• pp.97.1-102
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• 1999

This paper porposes and efficient coding scheme for remote medical communication systems, or“telemedicine systems”. These systems require a technique which is able to transfer large volume of data such as X-ray images effectively. We have already developed a hierarchical image coding and transmission scheme (HITS), which achieves an efficient transmission of medical images simply[1]. In this paper, a new coding scheme for HITS is proposed, which used hierarchical context modeling for the purpose of improving the coding efficiency. The hierarchical context modeling divides wavelet coefficients into several sets by the value of a correspondent coefficient in their higher class, or“a parent”, optimizes a Golomb-Rice (GR) code parameter in each set, and then encodes the coefficients with the parameter. Computer simulation shows that the proposed scheme is effective with simple implementation. This is due to fact that a wavelet coefficient has dependence on its parent. As a result, high speed data transmission is achieved even if the telemedicine system consists of simple personal computers.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.249.1-249.1
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• 2003

The Korea Chemical Bank (KCB) has more than 80,000 compound collections. provided from many companies, academies and institutes. KCB has supported high-throughput screening (HTS) against 80 biological targets and identified a number of hits over 20 targets. These hits were first validated by confirming the purity and novelty of anticipated compound. We also determined their physiochemical properties. (omitted)

• Proceedings of the Korea Information Processing Society Conference
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• 2011.04a
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• pp.1243-1244
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• 2011

블로그 이용이 활성화됨에 따라 포스트 랭킹 방법의 필요성이 증가하고 있다. 기존 연구에서는 HITS 에 기반을 둔 포스트 랭킹 방법인 BAITS 와 BAITS 를 수정한 포스트 랭킹 방법들을 제안한바 있다. 본 논문에서는 이러한 포스트 랭킹 방법들을 다양한 척도를 이용한 비교 실험을 통해 비교하여 가장 정확도가 높은 랭킹 방법을 판별하고자 한다.

• Structural Engineering and Mechanics
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• v.84 no.2
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• pp.253-268
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• 2022

Using non-destructive Acoustic Emission (AE) and optical Digital Image Correlation (DIC) methods, the moment-curvature behavior of steel and GFRP bars reinforced concrete beams under flexure was explored in this study. In the tension zone, laboratory studies were carried out on steel-RC and GFRP-RC beams with varying percentages of longitudinal reinforcement ratios of 0.33 %, 0.52%, and 1.11%. The distinct mechanism of cracking initiation and fracture progression of failure in steel-RC and GFRP-RC beams were effectively correlated and picked up using AE waveform characteristics of the number of AE hits and their amplitudes, AE energy as well as average frequency and duration. AE XY event plots and longitudinal strain profiles using DIC gives an online and real-time visual display of progressive AE activity and strains respectively to efficaciously depict the crack evolution and their advancement in steel-RC and GFRP-RC beams. They display a close matching with the micro and macro-cracks visually observed in the actual beams at various stages of loading.

• Journal of Korean Society of Transportation
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• v.35 no.6
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• pp.525-544
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• 2017

With the advent of the big data era, the interest in the development of land using traffic data has increased significantly. However, the current research on traffic big data lingers around organizing or calibrating the data only. In this research, a novel method for discovering the hidden values within the traffic data through data mining is proposed. Considering the fact that traffic data and network structures have similarities, network analysis algorithms are used to find valuable information in the actual traffic volume data. The PageRank and HITS algorithms are then employed to find the centralities. While conventional methods present centralities based on uncomplicated traffic volume data, the proposed method provides more reasonable centrality locations through network analysis. Since the centrality locations that we have found carry detailed spatiotemporal characteristics, such information can be used as an objective basis for making policy decisions.

• Smart Structures and Systems
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• v.30 no.1
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• pp.49-62
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• 2022

Experimental and discrete element methods were used to investigate the effects of triple joints lengths and triple joint angle on the failure behavior of rock mass under uniaxial compressive test. Concrete samples with dimension of 20 cm × 20 cm × 5 cm were prepared. Within the specimen, three imbedded joint were provided. The joint lengths were 2 cm, 4cm and 6 cm. In constant joint lengths, the angle between middle joint and other joints were 30°, 60°, 90°, 120° and 150°. Totally 15 different models were tested under compression test. The axial load rate on the model was 0.05 mm/min. Concurrent with experimental tests, the models containing triple joints, length and joint angle are similar to the experiments, were numerical by Particle flow code in two dimensions (PFC2D). Loading rate in numerical modelling was 0.05 mm/min. Tensile strength of material was 1 MPa. The results show that the failure behaviors of rock samples containing triple joints were governed by both of the angle and the length of the triple joints. The uniaxial compressive strengths (UCS) of the specimens were related to the fracture pattern and failure mechanism of the discontinuities. Furthermore, it was shown that the compressive behavior of discontinuities is related to the number of the induced tensile cracks which are increased by decreasing the joint length. Along with the damage failure of the samples, the acoustic emission (AE) activities are excited. There were only a few AE hits in the initial stage of loading, then AE hits rapidly grow before the applied stress reached its peak. In addition, every stress drop was accompanied by a large number of AE hits. Finally, the failure pattern and failure strength are similar in both methods i.e., the experimental testing and the numerical simulation methods.

• Advances in concrete construction
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• v.13 no.2
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• pp.199-213
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• 2022

Experimental and discrete element approaches were used to examine the effects of F shape non-persistent joints on the failure behaviour of concrete under uniaxial compressive test. concrete specimens with dimensions of 200 cm×200 cm×50 cm were provided. Within the specimen, F shape non-persistent joint consisting three joints were provided. The large joint length was 6 cm, and the length of two small joints were 2 cm. Vertical distance between two small joints change from 1.5 cm to 4.5 cm with increment of 1.5 cm. In constant joint lengths, the angle of large joint change from 0° to 90° with increments of 30°. Totally 12 different models were tested under compression test. The axial load rate on the model was 0.05 mm/min. Concurrent with experimental tests, numerical simulation (Particle flow code in two dimension) were performed on the models containing F shape non-persistent joint. Distance between small joints and joint angles were similar to experimental one. the results indicated that the failure process was mostly governed by both of the Distance between small joints and joint angles. The axial loading rate on the model was 0.05 mm/min. The compressive strengths of the samples were related to the fracture pattern and failure mechanism of the discontinuities. Furthermore, it was shown that the compressive behaviour of discontinuities is related to the number of the induced tensile cracks which are increased by increasing the joint angle. In the first, there were only a few acoustic emission (AE) hits in the initial stage of loading, and then AE hits rapidly grow before the applied stress reached its peak. Furthermore, a large number of AE hits accompanied every stress drop. Finally, the failure pattern and failure strength are similar in both approaches i.e., the experimental testing and the numerical simulation approaches.

• Molecules and Cells
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• v.39 no.5
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• pp.375-381
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• 2016

MicroRNAs (miRNAs) are small non-coding RNAs (~22 nucleotides) regulating gene expression at the post-transcriptional level. By directing the RNA-induced silencing complex (RISC) to bind specific target mRNAs, miRNA can repress target genes and affect various biological phenotypes. Functional miRNA target recognition is known to majorly attribute specificity to consecutive pairing with seed region (position 2-8) of miRNA. Recent advances in a transcriptome-wide method of mapping miRNA binding sites (Ago HITS-CLIP) elucidated that a large portion of miRNA-target interactions in vivo are mediated not only through the canonical "seed sites" but also via non-canonical sites (~15-80%), setting the stage to expand and determine their properties. Here we focus on recent findings from transcriptome-wide non-canonical miRNA-target interactions, specifically regarding "nucleation bulges" and "seed-like motifs". We also discuss insights from Ago HITS-CLIP data alongside structural and biochemical studies, which highlight putative mechanisms of miRNA target recognition, and the biological significance of these non-canonical sites mediating marginal repression.

• Genomics & Informatics
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• v.15 no.4
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• pp.147-155
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• 2017

Apurinic/apyrimidinic endonuclease 1 (APE1) is an enzyme responsible for the initial step in the base excision repair pathway and is known to be a potential drug target for treating cancers, because its expression is associated with resistance to DNA-damaging anticancer agents. Although several inhibitors already have been identified, the identification of novel kinds of potential inhibitors of APE1 could provide a seed for the development of improved anticancer drugs. For this purpose, we first classified known inhibitors of APE1. According to the classification, we constructed two distinct pharmacophore models. We screened more than 3 million lead-like compounds using the pharmacophores. Hits that fulfilled the features of the pharmacophore models were identified. In addition to the pharmacophore screen, we carried out molecular docking to prioritize hits. Based on these processes, we ultimately identified 1,338 potential inhibitors of APE1 with predicted binding affinities to the enzyme.