Jenkins (2000, 2007) suggested lingua franca core (LFC) of English as an international language (EIL) context. According to her, intelligibility of English pronunciation of L2 English speakers and English learners is more important than pronunciation accuracy in English communication. Her suggestion has been widely accepted in Korean classroom situations, so the systematic teaching of English pronunciation has been rarely emphasized. In this paper it is argued that the LFC of English is widely misinterpreted in Korea while some of her suggestions themselves are also misleading. This paper tries to redefine Jenkins' LFC and provide suggestions for teaching LFC in Korea.
Haroon, Saroona;Hashmi, Atif Ali;Khurshid, Amna;Kanpurwala, Muhammad Adnan;Mujtuba, Shafaq;Malik, Babar;Faridi, Naveen
Asian Pacific Journal of Cancer Prevention
/
v.14
no.7
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pp.4353-4358
/
2013
Introduction: Breast cancer aggressiveness can be correlated with proliferation status of tumor cells, which can be ascertained with tumor grade and Ki67 indexing. However due to lack of reproducibility, the ASCO do not recommend routine use of Ki67 in determining prognosis in newly diagnosed breast cancers. We therefore aimed to determine associations of the Ki67 index with other prognostic markers like tumor size, grade, lymph node metastasis, ER, PR and HER2neu status. Methods: A total of 194 cases of newly diagnosed breast cancer were included in the study. Immunohistochemical staining for ER, PR, HER2neu and Ki67 was performed by the DAKO envision method. Associations of the Ki67 index with other prognostic factors were evaluated both as continuous and categorical variables. Results: Mean age of the patients was 51.7 years (24-90). Mean Ki67 index was 26.9% (1-90). ER, PR, HER2neu positivity was noted in 90/194 cases (46.4%), 74/194 cases (38.1%) and 110/194 cases (56.70%) respectively. Significant association was found between Ki67 and tumor grade, PR, HER2neu positivity and lymph node status, but no link was apparent with ER positivity and tumor size. There wasan inverse relation between Ki67 index and PR positivity, whereas a direct correlation was seen with HER2neu positivity. However, high Ki67 (>30%) was associated with decreased HER2neu positivity as compared to intermediate Ki67 (16-30%). The same trend was established with lymph node metastasis. Conclusion: Our study indicates that with high grade tumors, clinical utility of ki67 is greater in combination with other prognostic markers because we found that tumors with Ki67 higher than 30% have better prognostic profile compared to tumors with intermediate Ki67 level, as reflected by slightly lower frequency of lymph node metastasis and HER2neu expression. Therefore we suggest that Ki67 index should be categorized into high, intermediate and low groups when considering adjuvant chemotherapy and prognostic stratification.
Giant cell arteritis, which is also referred to as temporal arteritis, is defined as a systemic vasculitis in individuals over 50 years of age. Here, we report a case of giant cell arteritis combined with oculomotor nerve palsy. An 81-year old female patient experienced a headache for 10 days in her left temporoparietal area, that was characterized by a continuous dull ache and heaviness with intermittent shooting and lancinating pain. Her symptoms persisted in spite of receiving strong analgesics in another hospital. Upon physical examination, she was found to have marked tenderness over the left temporal area, especially along the path of the temporal artery as well as limitation of adduction, supraduction and infraduction of the left eyeball. At the time of admission, her erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were 52 mm/hr and 3.94 mg/dl. In addition her brain MRI revealed no specific findings. Giant cell arteritis was suspected based on the clinical symptoms and signs as well as the elevated ESR and CRP. Oral steroid therapy started was started with an initial dose of 40 mg of prednisolone per day that was gradually tapered to 5 mg a day for 2 weeks. Her headache subsided one day after the steroid therapy and oculomotor nerve palsy was markedly improved after 2 weeks of the therapy. After 2 months she had recovered completely from her symptoms.
Choi, Doo-Ho;Kim, Eun-Seog;Kim, Yong-Ho;Jin, So-Young;Lee, Dong-Wha;Haffty, Bruce G.
Radiation Oncology Journal
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v.22
no.4
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pp.307-315
/
2004
Purpose: The purpose of this work was to study the differences of cyclooxygenase (COX-2) expression between Korean and Caucasian patients with early-onset breast carcinoma by immunohistochemistry. The test were analyzed to find a correlation between COX-2 and other biomarkers including HER-2/neu amplification, because we previously reported that a significant difference had been found in the expression of HER-2/neu between the two races. Furthermore, we investigated prognostic significance of COX-2 in korean patients. Materials and Methods: Sixty Korean women who were diagnosed breast carcinoma at 45 years old or younger and 60 Caucasian women with breast carcinoma were selected for this study. The median age of both groups was 37 years and tumor sizes were distributed evenly between the two group. Paraffin embedded blocks of primary tumor were processed for immunohistochemical staining of COX-2. The COX-2 expression was evaluated according to the percentage of positive cells and the intensity of staining. And the results were compared with the data of the previous studies to find correlation between COX-2 and other parameters and survival data. Results: Proportion of the COX-2 expression in total patients was $27.6\%$. The percentage of tumors that stained positive for COX-2 in korean and Caucasian women with early-onset breast carcinoma were $37.9\%$ and $20.8\%$, respectively. The difference was statistically not significant(p=0.090). Expression of COX-2 was not associated with several clinicopathologic parameters including HER-2/neu overexpression, but negative estrogen receptor status was correlated with significance (p=0.046). The 5 year disease free survival rate for patients with COX-2 expression was $67.9\%$, compared to $81.9\%$ of the COX-2 negative patients and the result was statistically not significant. Conclusions : A significant difference was not found in the expression of COX-2 between the two groups of patients with early-onset breast carcinoma. And correlation between COX-2 and other parameters was not observed except estrogen receptor negativity. Large scaled further research including radiotherapy factors will be needed to identify COX-2 as a prognostic role in patients with early-onset breast carcinoma.
The study reported a phenomenological analysis of the interviews with 19 mothers who had a child preparing a college entrance examination. The research question was what mothers experienced in supporting their child in his/her study for the examination. Results indicated that 'the senior year in a highschool' was described as the most stressful period affecting all the family members. Mothers' experiences were portrayed from three perspectives: mothers, as family members, experiencing the attachment to her child but conflicts with her husband; mothers, as individuals, adjusting by trying to setting realistic academic goals for her child while supporting him/her physically, emotionally, and spiritually; and mothers, as critics to extrafamily systems, blaming the inconsistency of educational policies. 1bis study was conducted with a holistic view, and highlighted the importance of interactions between traditional ideology about the mother roles and socioeconomic contexts when interpreting mothers' supporting their child in study for a college entrance examination.
Kleine-Levin syndrome is a rare disorder characterized by recurrent episodes of hypersomnia, hyperphagia, hypersexuality and delusion and hallucination with spontaneous recovery. A 17-year-old female suddenly showed hypersomnia, severe fatigue, and compulsive hyperphagia. She was diagnosed with suspected Kleine-Levin Syndrome. The precipitating factor was an upper respiratory tract infection that the patient had undergone 2 weeks prior. Past psychiatric history included somnambulism and ADHD; her symptoms of ADHD included attention deficit, impulsiveness, hyperactivity, and irritability. This was her third episode. Her hypersomnia was longer in duration but lower in frequency compared with usual KLS. Her low LF/HF ratio in heart rate variability measurement showed high parasympathetic nerve activity. A MMPI report showed some psychological problem. The patient was diagnosed of gastric fever by pattern identification. Her hypersomnia episode improved 6 weeks after onset. This is the first reported case of suspected Kleine-Levin Syndrome in the field of Oriental Medicine in Korea.
The stdy of this study is to explore whether there is a social class difference in the relationship of mother and daughter-in-laws. The findings and summarized as follows. in the upper class the relationship of mother and daughter-in-laws seems 'fictitious one' In the middle class when her husband's occupation status is higher than his father's the relationship of mother and daughter-in-laws seems 'the relationship which is trobultesome only on daughter-in-law's behalf. When her husbands' occupation status is similar to his father's and her family is living together with in-laws and she and her mother-in=law are housewives the relationship of mother and daughter-in-laws seems 'the troublesome relationship for the both parts of mother and daughter-in-laws' In the same situation as above except the fact that the mother-in-law is housewife and daughter-in-law working the relationship between mother and daugther-in-laws seems apper to be 'interdependence' When her husband is self- mployed the daughter-in-laws keeps the interdepen-dent relationship with the mother-in-law. In the low class the relationship of mother and daughter-in-laws seems 'neglect' or 'conflicting'.
The purpose of this research is to grasp the factors behind a mother's behavior in purchasing baby's clothes and to investigate how her purchasing behavior is affected by the baby's age, sex, rank, her age, her educational background, her place of residence, her occupation, the number of children's and family's monthly income. for this purpose, questionnaires were used and personal interviews with 481 mothers who bring up from newborns to two-year-old babies in Seoul ere conducted. Through this research, some facts have been found as follows. 1. Mother's behavior in purchasing baby's clothes are affected by baby's variables such as the baby's age, sex and rank, particularly it is much affected by baby's rank. 2. Mother's behavior in purchasing baby's cloths are affected by mother's variables such as the mother's age, educational background, place of residence, occupation, the number of children's and family's monthly income. Particularly it is much affected by mother's educational background and family's monthly income.
Flannery O'Connor's stories have garnered critical attention for her religious views. Thus, the interpretation of violence in her fiction has been mainly associated with salvation in her characters. Nonetheless, O'Connor was aware of the historical facts surrounding white supremacist activities in the American South. In its revenge narrative, O'Connor's story "The Displaced Person" (1955) unveils subtle layers of politics from the Ku Klux Klan as well as her white characters' views of race and immigrants. O'Connor used a voice of reserve due to her minority position as woman and Catholic. Although she was a white female, she lived within repressive Southern religiosity. Racism prevailed beneath Southern chauvinism and patriotism. The conflicts in the South display the violent aspects of the "Invisible White Supreme Empire." After the World Wars, devalued whiteness elicited atrocities against socially upward mobile African Americans, foreigners and Catholics. This article explores the convoluted issues of racial hierarchy, miscegenation, and xenophobic reactions in the South.
Based on the Greek myth of Pygmalion and the fairy tale of Cinderella, Shaw's Pygmalion demonstrates a masterful coalescence of these two narrative motifs into a coherent plot scheme. Even more significant is his keen insight into the conflicts created at the tripartite intersection of human activity concerning language/class/culture, which, as the leitmotif, revolves around lessons in language learning. This play basically deals with human transformation and by its very nature, Higgins's experimentation with transforming Eliza cannot stop at language alone. Her cultural transformation ripples over into the realms of gesture and even a unique way of living (modus vivendi) intimately associated with taste and manners, which Bourdieu terms as habitus. By acquiring a new fashion and language, Eliza is reborn as a new lady aspiring to be filled with a newly acquired habitus. While separating her from her old Cockney style, Higgins inculcates Queen's English in Eliza, in which process her changed speech styles gradually transforms and restructures her deportment and manners, finally generating new practices, perceptions and attitudes. The gist of Pygmalion is however less Eliza's ascent into the middle class than her battle for symbolic capital waged at the level of language. By problematizing his contemporary practice of habitus conventionalized and warped by class distinctions based on economic, social and cultural capitals, Shaw creates a new humanist model of man founded on spiritual and rational virtues. In conclusion, Eliza is not a frigid Galatea but a dynamic character that goes through a brilliant transformation of three stages: 1) linguistic; 2) cultural, and 3) humanist. Finally she is built into a "consort battleship" on an equal standing with her sculptor. The process of her character-building cannot be illuminated without resorting to the dynamic notion of habitus, which highlights the process of inculcation, structuring, generation and transposing. Given the overwhelming weight of the heroine's role and the dynamic process of her transformation as the major plot scheme, this play should be christened Galatea in lieu of Pygmalion.
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