• Journal of Acupuncture Research
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• 제25권3호
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• pp.115-125
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• 2008

Diabetes mellitus is a worldwide epidemic. Global projections suggest that most nations will have a doubling of the incidence of Diabetes mellitus(DM) within 20years. The Herb-Combined Remedy(HCR) of DM was known as one of anti-hyperglycaemic agents. But it is unclear whether HCR can be used to treat patients with Diabetic nephropathy or not. The present study was designed to investigate the anti-hyperglycaemic and preventive effects from diabetic nephropathy of HCR in STZ-induced diabetic rats. Treatment with HCR regulated blood glucose levels, but did not affect body weights. In addition, HCR was able to decrease blood glucose levels after 120min. Serum BUN levels were not effective but, serum Creatinine levels were lowered by treatment with HCR or MF. In histopathological observation of renal tissue, both HCR and MF groups showed decreased tendency of inflammation and renal injury. In conclusion, these results demonstrate that HCR is effective to treat patients with DM and also has preventive activity on diabetic nephropathy.

• Journal of Acupuncture Research
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• 제25권1호
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• pp.57-72
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• 2008

Objectives : The Herb-combined Remedy(HCR) for diabetes mellitus is known as an anti-hyperglycaemic agent. But its exact mechanisms are unclear. The present study was carried out to investigate its anti-hyperglycaemic and anti-oxidative effects in STZ-induced diabetic rats. Methods : Experimental diabetes was induced by injection of STZ(80mg/kg) to ratsvia the peritoneum. The experimental animals were divided into 4 groups : normal group, control group(STZ-induced diabetic rats with no treatment), HCR group(STZ-induced diabetic rats with HCR treatment), MF group(STZ-induced diabetic rats with Metformin treatment). The effects of HCR on STZ-induced diabetes was observed by measuring fasting blood glucose, changes of body weight, food uptake, and water uptake glucose levels in the normal state decline rates in blood glucose levels DPPH free-radical scavenging activity superoxide dismutase in RBC lysate catalase activity in RBC lysate and glutathione reductase activity in RBC lysate. Results : Treatment with HCR regulated blood glucose levels. Treatment with HCR also prevented weight loss in STZ-induced diabetic rats. In addition, oral glucose tolerance decreased following treatment with HCR. Direct anti-oxidative effects on DPPH free-radical scavenging were not observed, but treatment with HCR elevated SOD levels in blood cell lysates from STZ-induced diabetic rats. In addition, the HCR-treatment group showed an elevated tendency to glutathione reductase activity. Conclusions : These results demonstrate that HCR has anti-hyperglycaemic and anti-oxidative effects in STZ-induced diabetic rats.

• 대한본초학회지
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• 제30권2호
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• pp.43-48
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• 2015

Objectives : The aim of this study was to investigate the memory enhancing properties of extract of Hoelen Cum Radix (HCR) and its possible mechanism in mice of normal condition. Methods : We evaluated the effects of HCR on cognitive function and memory enhancement in normal mice. Male ICR mice were orally administrated with HCR 100 mg/kg for 7 days and equal volume of saline was administrated to the control group in the same condition. We conducted two behavioral tests which measure the spatial working memory (Y-maze test) and cognitive fear memory (passive avoidance test). We also investigated whether HCR affects the hippocampal neurogenesis in the brain. To assess the effects of HCR on neural progenitor cell differentiation and neurite outgrowth in the early stage of hippocampal neurogenesis, we performed doublecortin (DCX), a direct neurogenesis marker, immunohistochemical analysis in the dentate gyrus (DG) of the mouse hippocampus. Results : HCR significantly enhanced memory and cognitive function as determined by the Y-maze test (p<0.05) and passive avoidance test (p<0.001). Moreover, HCR increased DCX positive cells (p<0.01) and neurite length (p<0.01) compared to the control group. These results indicated that HCR stimulates differentiation of neural progenitor cells and promotes neurite outgrowth in hippocampal DG of the mice. Conclusion : We concluded that HCR shows memory enhancing effects through the stimulation of hippocampal neurogenesis as a consequence of accelerated neuronal differentiation and neurite outgrowth in the DG of the hippocampus after HCR treatment.

• 접착 및 계면
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• 제14권4호
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• pp.192-196
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• 2013

본 연구에서는 polypropylene (PP)을 기본 고분자로 하여, 석유수지(hydrocarbon resin, HCR) 종류와 함량을 달리하여PP/HCR 블랜드의 열량 거동을 분석하였고, 이를 이용하여 bi-axially oriented polypropylene (BOPP) 필름을 제조한 후 필름의 기계적 물성, 광학적 특성, 가스 및 수증기에 대한 투과도 그리고 수축률을 비교 평가하였다. 이 연구에서 HCR로는 수첨 dicyclopentadiene (DCPD) 수지와 수첨 C9 수지가 사용되었다. Homo-PP 대비 PP/HCR 블랜드는 stiffness의 증가 등 필름의 기계적 물성 증가, 필름의 haze 감소 등의 광학적 특성 향상, 가스 및 수증기에 대한 투과도 감소 그리고 필름의 수축률이 증가되었으며, HCR로 사용된 수첨DCPD수지와 수첨 C9수지는 기계적 물성 및 광학적 물성에서는 유사한 기여도를 보이지만, 가스 및 수증기에 대한 투과도와 필름의 수축률에 있어서는 차이를 보였다.

• 한국통신학회논문지
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• 제22권10호
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• pp.2282-2291
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• 1997

본 논문은 분산된 가입자 댁내 ATM 망 및 소규모 사업장 ATM 망의 고속 멀티미디어 서비스응용에 적용하기 위한 공유매체 접속 프로토콜의 구조와 프로토콜의 성능 분석 및 집적회로 구현에 관한 것으로서 본 논문은 제 I부에서 제안된 HCR 프로토콜의 집적회로(Integrated Circuit)설계에 관하여 다룬 제 II부이다. 설계된 HCR용 IC는 기존의 ATM 프로토콜 IC들과 호환되도록 설계하였으며 입출력 인터페이스는 UTOPIA 접속 규격에 따랐다. 시뮬레이션 결과 본 집적회로는 현재의 쿼타 상태, 우선순위, 데이터의 유무에 따라 실시간 또는 비실시간 데이터를 효과적으로 처리함을 보였으며, 설계 변경없이 기존의 ATM IC와 사용되어 멀티미디어 서비스 응용에 유용하게 사용될 수 있다.

• 한국에너지공학회:학술대회논문집
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• 한국에너지공학회 2000년도 춘계 학술발표회 논문집
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• pp.153-157
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• 2000

• 대한전자공학회논문지SP
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• 제41권6호
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• pp.61-71
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• 2004

얼굴검출을 위한 다양한 연구가 행해지고 있으나 아직도 실시간성의 확보는 미진하다. 이에 본 연구는 연속영상에서 컬러와 움직임 정보를 이용한 실시간 얼굴검출 방법을 제안한다. 피부색 검출을 위한 컬러공간은 조명의 변화에 강인하고 피부색을 좁은 영역으로 정의할 수 있는 Hue와 Cr성분을 조합하여 재구성한 HCr을 사용한다. 배경참조영상 기반에서 밝기와 Cr 성분을 함께 사용하여 획득한 움직임 영역에서, HCr과 적응적 임계값을 이용해서 피부색 영역을 검출하고, 그 검출된 영역의 모양과 크기정보를 통해 얼굴 후보영역을 구한다. 이렇게 구해진 얼굴후보영역에서 G와 B성분의 차이, 밝기, Cr성분 값과 눈과 입의 위치 및 거리관계를 이용하여 눈과 입을 검출하여 얼굴을 확정한다. 실험결과 연속영상에서 실시간으로 얼굴을 검출 할 수 있었다.

• 한국토양비료학회지
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• 제26권3호
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• pp.197-203
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• 1993

항생제 내성변이 균주 HCR-46 $str^{r}cep^{r}$과 CB756 $str^{r}rif^{r}$를 종자피복방법(種子被覆方法)으로 땅콩에 접종(接種)하여 3처리(處理)의 온도(溫度)에 생육(生育)시켜 근권(根圈)에서 접종균주(接種菌株)의 밀도(密度)와 근류형성(根瘤形成) 경합(競合)등에 관하여 조사하였다. 접종균주(接種菌株)는 땅콩의 생육(生育)과 함께 증식(增殖)되었고 식물체(植物體) 뿌리 g당(當) 증식속도(增殖速度)는 파종후(播種後) 10~15일(日) 사이에 가장 빨랐다. 온도간(溫度間) 증식속도(增殖速度)는 $28^{\circ}C$>$34^{\circ}C$>$22^{\circ}C$순(順)이었으며 접종균주간(接種菌株間)에는 HCR-46 $str^{r}cep^{r}$ 균수(菌洙)가 CB756 $str^{r}rif^{r}$ 균주(菌株)보다 $22^{\circ}C$와 $28^{\circ}C$에서는 더 높았고, $34^{\circ}C$에서는 비슷하였다. HCR-46 $str^{r}cep^{r}$ 및 CB756 $str^{r}if^{r}$ 균주(菌株)를 단일접종시(單一接種時) 처리(處理)한 모든 온도(溫度)에서 근류(根瘤)의 대부분이 각 균주(菌株)에 의하여 점유(占有)되었으나, 2개(個) 균주(菌株)를 혼합접종시(混合接種時)에는 $22^{\circ}C$와 $28^{\circ}C$에서는 HCR-46 $str^rcep^r$ 균주(菌株)에 의한 근류(根瘤) 점유율(占有率)이 CB756 $str^{r}rif^{r}$에 비(比)하여 월등(越等)히 높았고 $34^{\circ}C$에서는 2균주(菌株)가 비슷한 비율(比率)로 점유(占有)하였다. 식물체(植物體) 건물중(乾物重), 근류형성능(根瘤形成能), 질소흡수량(窒素吸收量), 질소고정력(窒素固定力)은 대체로 $28^{\circ}C$>$34^{\circ}C$>$22^{\circ}C$순(順)이었으며, CB756 $str^{r}if^{r}$ 균주(菌株)보다 HCR-46 $str^{r}cep^{r}$ 또는 이들 2개혼합(個混合) 균주(菌株) 접종(接種)이 더 높았다.

• Preventive Nutrition and Food Science
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• 제18권1호
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• pp.67-75
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• 2013

Descriptive analysis and consumer acceptance tests were conducted with frozen (FCR), homemade (HCR), and aseptic-packaged (ACR) cooked rice products from two cultivars-IM and SD. FCR was prepared using a rapid freezing process, which may provide consumers with a quality similar to that of HCR. The intensity of the flavors of roasted, glutinous rice, rice cake, and rice starch and the textures of glutinousness, moistness, chunkiness, adhesiveness, and squishiness were all greater in the FCR as compared to the HCR and ACR (p<0.05) in IM and SD cultivars. The differences in sensory characteristics between the FCR and ACR were larger than the equivalent differences between the FCR and HCR. Overall consumer acceptance ratings for FCR in overall aspect, appearance, aroma, and texture were not significantly different compared to those for HCR (p>0.05); however, in most cases these factors showed significant differences when compared with ACR (p<0.05). From partial least square regression analysis, cooked rice was positively related to sweet, transparency, glossiness, roasted, glutinousness, chunkiness, moistness, glutinous rice, adhesiveness, rice shape, rice starch, and squishiness attributes but negatively related to raw rice, old rice, old rice aroma, a particle feeling, off-aroma, white color, scatteredness, slickness, size of cooked rice, and firmness attributes.

• International Journal of Computer Science & Network Security
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• 제24권2호
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• pp.101-112
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• 2024

Telugu language is considered as fourth most used language in India especially in the regions of Andhra Pradesh, Telangana, Karnataka etc. In international recognized countries also, Telugu is widely growing spoken language. This language comprises of different dependent and independent vowels, consonants and digits. In this aspect, the enhancement of Telugu Handwritten Character Recognition (HCR) has not been propagated. HCR is a neural network technique of converting a documented image to edited text one which can be used for many other applications. This reduces time and effort without starting over from the beginning every time. In this work, a Unicode based Handwritten Character Recognition(U-HCR) is developed for translating the handwritten Telugu characters into English language. With the use of Centre of Gravity (CG) in our model we can easily divide a compound character into individual character with the help of Unicode values. For training this model, we have used both online and offline Telugu character datasets. To extract the features in the scanned image we used convolutional neural network along with Machine Learning classifiers like Random Forest and Support Vector Machine. Stochastic Gradient Descent (SGD), Root Mean Square Propagation (RMS-P) and Adaptative Moment Estimation (ADAM)optimizers are used in this work to enhance the performance of U-HCR and to reduce the loss function value. This loss value reduction can be possible with optimizers by using CNN. In both online and offline datasets, proposed model showed promising results by maintaining the accuracies with 90.28% for SGD, 96.97% for RMS-P and 93.57% for ADAM respectively.