• Journal of Sasang Constitutional Medicine
• /
• v.22 no.1
• /
• pp.49-58
• /
• 2010

1. Objectives: The purpose of this study is to find out the Anti-Oxidative effects of Soyangin Hyeongbangpaedok-san(HBP) in kidney and spleen cells of aged rats. 2. Methods: Aged rats used in this experiment were 6, 52, 68 weeks old. Each age group was divided into three groups again. One group was given no treatment, another group was dosed normal saline and the other group was dosed HBP decoction. The antioxidant effects of HBP decoction were measured by the levels of SOD, GSH, MDA and NO. 3. Results: and Conclusions: 1) The activity of SOD was significantly increased in kidney cells of 68w-HBP group. Deterioration of the activity of SOD in kidney cells was significantly suppressed according to increasing in age of the week. 2) The level of NO was significantly decreased in kidney cells of 68w-HBP group. Deterioration of The level of NO in kidney cells was significantly suppressed according to increasing in age of the week. 3) The activity of SOD was increased in spleen cells of 52w and 68w-HBP group. 4) The level of GSH was significantly increased in spleen cells of 68w-HBP group.

• Journal of Biomedical Engineering Research
• /
• v.24 no.5
• /
• pp.381-389
• /
• 2003

Various adult diseases (cerebral apoplexy, athymiait, etc.) result from hypertension, blood circulation disturbance and increment of HBP. In early diagnosis of these diseases, MRI, X-ray and PET have been used rather aim for treatment than for a prevention of disease. Since. cerebral apoplexy and athymiait could appear to the regular/irregular persons, it is very important to measure HBP which has connection with cerebral blood flow state. HBP has more diagnosis elements than that of BP. So, we can diagnose accurate hypertension by measuring of HBP. But, existing sphygmomanometers and automatic BP monitors can not measure HBP, and can not execute complex function(measuring of BP/HBP, blood flow improvement). Purpose of this paper is to develop a system and algorithm which can measure BP/HBP for accurate diagnosis. Also, we extracted diagnosis factors by correlativity analysis of BP/HBP. Maximum pressure of HBP corresponds to 62% that of BP, Minimum pressure of HBP corresponds to 46% that of BP. Therefore, we developed the multi-function automatic blood pressure monitor which can measure BP/HBP and improve cerebral blood flow state.

• ETRI Journal
• /
• v.31 no.2
• /
• pp.151-161
• /
• 2009

In this paper, we propose an adaptive multiview video coding scheme based on spatiotemporal correlation analyses using hierarchical B picture (AMVC-HBP) for the integrative encoding performances, including high compression efficiency, low complexity, fast random access, and view scalability, by integrating multiple prediction structures. We also propose an in-coding mode-switching algorithm that enables AMVC-HBP to adaptively select a better prediction structure in the encoding process without any additional complexity. Experimental results show that AMVC-HBP outperforms the previous multiview video coding scheme based on H.264/MPEG-4 AVC using the hierarchical B picture (MVC-HBP) on low complexity for 21.5%, on fast random access for about 20%, and on view scalability for 11% to 15% on average. In addition, distinct coding gain can be achieved by AMVC-HBP for dense and fast-moving sequences compared with MVC-HBP.

• Reproductive and Developmental Biology
• /
• v.32 no.4
• /
• pp.211-215
• /
• 2008

The HMG box containing protein (HBP) has a high mobility group domain and involved in the regulation of proliferation and differentiation of tissues. We screened HBP2 in glioblastoma using Suppression Subtractive Hybridization (SSH) and isolated human spermatogonial stem cell-like cells (hSSC-like cells) derived from patients of nonobstructive azoospermia (NOA). Expression of HBP2 was analyzed by RT-PCR in undifferentiated stem cells (human Embryonic Stem Cells, hSSC-like cells 2P) and spontaneous differentiated stem cells (hSSC-like cells 4P). It was overexpressed in hESC and hSSC-like cells 2P but not in hSSC-like cells 4P. Also, the expression level of HBP2 was downregulated in colon tumor tissues compared to normal tissues. Specifically in synchronized WI-38 cells, HBP2 was highly upregulated until the G1 phase of the cell cycle and gradually decreased during the S phase. Our results suggest that HBP2 was downregulated during the spontaneous differentiation of hSSC-like cells. HBP2 was differently expressed in colon tissues and was related to G1-progression in WI-38 cells. It may playa role in the maintenance of an undifferentiated hSSC-like cell state and transits from G1 to S in WI-38 cells. This research was important that it identified a biomarker for an undifferentiated state of hSSC-like cells and characterized its involvement to arrest during cell cycle in colon cancer.

• Journal of the Institute of Electronics Engineers of Korea SC
• /
• v.40 no.6
• /
• pp.58-67
• /
• 2003

Many adult diseases(cerebral apoplexy, athymiait, etc.) result from hypertension, blood circulation disturbance and increment of HBP. In early diagnosis of these diseases, MRI, X-ray and PET have been used rather aim for treatment than prevention of a disease. Since, cerebral apoplexy and athymiait have been caused to the regular/irregular persons, it is very important to measure HBP which has connection with cerebral blood low state. HBP has more diagnosis elements than that of BP. So, we can diagnose accurate hypertension by measuring of HBP. But, existing sphygmomanometers and automatic BP monitors can not measure HBF, and can not execute complex function(measuring of BP/HBP, blood flow improvement). The purpose of this paper is to develop the system and algorithm which can measure BP/HBP for accurate diagnosis. Also, we extracted diagnosis factors by the correlativity analysis of BP/HBP. The maximum pressure of HBP corresponds to 62% that of BP, the minimum pressure of HBP corresponds to 46% that of BP. Therefore, we developed the multi function automatic blood pressure monitor which can measure BP/HBP and improve cerebral blood flow state.

• Investigative Magnetic Resonance Imaging
• /
• v.22 no.1
• /
• pp.1-9
• /
• 2018

Purpose: This study was designed to optimize the flip angle (FA) and scan timing of the hepatobiliary phase (HBP) using the 3D T1-weighted, gradient-echo (GRE) imaging with controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) technique on gadoxetic acid-enhanced 3T liver MR imaging. Materials and Methods: Sixty-two patients who underwent gadoxetic acid-enhanced 3T liver MR imaging were included in this study. Four 3D T1-weighted GRE imaging studies using the CAIPIRINHA technique and FAs of $9^{\circ}$ and $13^{\circ}$ were acquired during HBP at 15 and 20 min after intravenous injection of gadoxetic acid. Two abdominal radiologists, who were blinded to the FA and the timing of image acquisition, assessed the sharpness of liver edge, hepatic vessel clarity, lesion conspicuity, artifact severity, and overall image quality using a five-point scale. Quantitative analysis was performed by another radiologist to estimate the relative liver enhancement (RLE) and the signal-to-noise ratio (SNR). Statistical analyses were performed using the Wilcoxon signed rank test and one-way analysis of variance. Results: The scores of the HBP with an FA of $13^{\circ}$ during the same delayed time were significantly higher than those of the HBP with an FA of $9^{\circ}$ in all the assessment items (P < 0.01). In terms of the delay time, images at the same FA obtained with a 20-min-HBP showed better quality than those obtained with a 15-min-HBP. There was no significant difference in qualitative scores between the 20-min-HBP and the 15-min-HBP images in the non-liver cirrhosis (LC) group except for the hepatic vessel clarity score with $9^{\circ}$ FA. In the quantitative analysis, a statistically significant difference was found in the degree of RLE in the four HBP images (P = 0.012). However, in the subgroup analysis, no significant difference in RLE was found in the four HBP images in either the LC or the non-LC groups. The SNR did not differ significantly in the four HBP images. In the subgroup analysis, 20-min-HBP imaging with a $13^{\circ}$ FA showed the highest SNR value in the LC-group, whereas 15-min-HBP imaging with a $13^{\circ}$ FA showed the best value of SNR in the non-LC group. Conclusion: The use of a moderately high FA improves the image quality and lesion conspicuity on 3D, T1-weighted GRE imaging using the CAIPIRINHA technique on gadoxetic acid, 3T liver MR imaging. In patients with normal liver function, the 15-min-HBP with a $13^{\circ}$ FA represents a feasible option without a significant decrease in image quality.

• Korean Journal of Environmental Biology
• /
• v.18 no.1
• /
• pp.33-39
• /
• 2000

Gordona sp. MS6, desulfurizing petroleum, can convert dibenzothiophene (DBT) to 2-hydroxybiphenyl (2-HBP) and sulfate. In this study, the effect of DBT degradation product on DBT desulfurization activity was investigated. When $Na_2$SO$_4$ and DBT were simultaneously added in the medium sulfur sources, specific growth rate of strain MS6 was doubled compared to not adding $Na_2$SO$_4$. But, sulfate inhibited DBT desulfurization rate, furthermore, when 0.05 g/L $Na_2$SO$_4$ was supplied DBT desulfurization rate decreased down to 40%. When 2-HBP and its derivative, 2, 2'-dihydroxybiphenyl (DHBP) were not added, DBT desulfurization rate was 5.0 $\mu$mol L$^{-1}$ㆍh$^{-1}$. With the increase of 2-HBP and DHBP concentration, DBT desulfurization rate was decreased. No DBT desulfurization activity of Gordona sp. MS6 was observed when initial concentration was over 0.15 mM 2-HBP and 0.8 mM DHBP [Gordona sp., Desulfurization, Dibenzothiophene, 2-Hydroxybiphenyl, Sulfate].

• Research in Community and Public Health Nursing
• /
• v.7 no.1
• /
• pp.80-99
• /
• 1996

Young black men(YBM) have the most severs levels of high blood pressure(HBP) and, in all reports but one, the lowest of HBP control of any age /sex /race group. To increase entry into care, remaining in care, and BP control for young(18-49 years) Black men, It is needed to review socio-demographic, medical characteristics, and behaviors(importance of and difficulty with HBP control behaviors, or worry about mdication) for experimental intervention study(educational- behavior strategies) of hypertensive urban young black men. The 204 participants had an average age of 38.8+7.0 years and an average educational level of $11.0{\pm}2.4$ years; only 23.1% were employed full- or part-time while 26% were on disability ; and 6% were married. Only 35.3% had an MD for HBP care and 37.3% had some form of health insurance. The average BP of those men currently being in care on medication(35.3%) was $148.2/95.1{\pm}19.5/11.3$ compared to those men not taking HBP care $153.7/99.1{\pm}14.0/9.8(p<.05)$. The average creatinine level was 1.3(excluding 3 marked elevations of 15.9, 9.6, and 7.7) for the 163 men consenting to have their blood drawn. Self-reported co-morbidity induded heart disease 7.8%, diabetes 8.9%, high cholesterol 18.2%, CVA 3.4%, alcohol and drug related problems 27.9% and 22.5% respectively. The kidney disease of those men currently being in care & on medication was 9.7 compared to those men not taking HBP care 0.8(p<.05). The problems of with sex life, physicl activity and dearly thinking of those men currently being in care & on medication was higher compared to those men not taking HBP care(p<.05). Questions of 'during the past month, on how many days did you have 5 or more drinks (bottles) of any alcoholic beverag?' and smoking of those men currently being in care & on medication was 18.1% and 72.2% compared to those men not taking HBP care 27.3 and 82.6%, respectively. HBP control behaviors was assessed with 1-5 point Likert subscales(5=extreme, 1-none at all), In general, th men reportd low levels of perceived psychological barrier to HBP care and control behaviors; importance of and difficulty with HBP control behaviors, or worry about mdication. For example, on a five point scale(1=none at all, 5=extreme), average ratings for perceived important and difficulty with BP care and behaviors were 2.8(SD=1.2) and 2.5(SD=1.1). Average ratings for perceived benefit with BP care and behaviors worry about medication of those men currently being in care on medication was 4.0(SD=0.9) and 2.2(SD=1.1) compared to those men not taking HBP care 3.6(SD=0.8), 2.8 (SD=1.6) respectively(p<.05). These data support the need for educational-behavioral strategies of community health nurse to improve high blood pressure control in this high risk group through perceived barriers to treatment, health care skills and use of resources, and social support.

• Reproductive and Developmental Biology
• /
• v.31 no.3
• /
• pp.133-137
• /
• 2007

The objective of the study was to determine the relationship between the mRNA expression levels of sperm phospholipids hydroperoxide glutathione peroxidase (PHGPx) and heparin-binding protein (HBP), and in-vivo fertility in boars. The farrowing rate was not correlated with litter size. Sperm PHGPx mRNA expression level of the larger litter size (over 10) group $(2,414.7{\pm}400.7)$ was high that of smaller litter size (below 8) group $(1,875.8{\pm}311.2)$. Sperm HBP mRNA expression level was also higher in the larger litter size $(2,255.9{\pm}360.8)$ group than the smaller litter size $(2,155.4{\pm}378.0)$. However, significant differences were not observed. Sperm PHGPx mRNA level was correlated positively with litter size (r=0.206). Because the expression levels of PHGPx and HBP are not strongly correlated with in-vivo fertility, PHGPx and HBP can not be considered a predictive measure for fertility in boars.

• Journal of Korean Society of Forest Science
• /
• v.97 no.3
• /
• pp.221-228
• /
• 2008

This study was conducted to understand the effect of the different treatment level of head back pruning (HBP) on flowering, fruiting and nut qualities. The average number of pistillate flowers per bearing mother branch (BMB) ranged greatly from 0.5 to 60.0. For all cultivars as the level of HBP treatment increases, the number of pistillate flowers per bearing branch (BB) and BMB decreased. For all cultivars the number of branches developed per BMB began to decrease above 30% HBP treatment level. The number of burrs per BB ranged from 1.0 to 2.0. Within 'Daebo' the number of burrs per BB increased with increasing HBP treatment level. The rate of fallen fruits was the lowest of 22.6% at the 50% HBP treatment level of 'Tsukuba', whereas the rate was the highest in 'Pyeonggi'. Nut weight increased with decreasing the number of burrs per BB. Nut yield per BMB showed a tendency of decreasing with increasing the HBP treatment level. Within a HBP treatment level nut grade indicating nut quality varied greatly among cultivars. For all cultivars except for 'Pyeonggi', the proportion of specially large nuts above the average weight increased as the HBP treatment level increased. The soluble solids content showed no significant difference among the HBP treatment levels just right after harvesting of nuts. After 8 weeks of harvesting, however, the soluble solids content increased about 3.3% to 5.3%. and was highest at the 50% HBP treatment level. There were no significant differences among the HBP treatment levels and cultivars in the nut hardness which is highly related to the storage as well as the initial soluble solid content.