• Clinical Nutrition Research
• /
• 제12권3호
• /
• pp.218-228
• /
• 2023

Recent studies have evaluated the association between specific beverage intake and metabolic risks in adults. However, more evidence is needed to examine the association between the Healthy Beverage Index (HBI) and metabolic factors. Therefore, this study investigated the relationship between HBI and metabolic factors in adults. In this cross-sectional study, 338 overweight and obese individuals living in Tabriz, Iran were selected. Data on beverage consumption, demographics, physical activity, and anthropometric characteristics were evaluated using validated standard protocols. The predefined HBI was calculated based on previous studies. The mean value of HBI index among all of the participants was 59.76 ± 6.51. Those at the higher HBI scores had significantly lower waist circumference, waist-to-hip ratio, fat mass, and weight (p < 0.05). HBI and triglyceride scores also had a significant relationship. It has been shown that at higher HBI scores compared to lower scores, high-density lipoprotein cholesterol levels increase while homeostatic model assessment for insulin resistance, low-density lipoprotein cholesterol, total cholesterol, and blood pressure decrease. HBI scores higher among Iranian adults were associated with a better chance of losing weight and weight loss and a better lipid profile, and lower blood pressure. Therefore, HBI can be a useful and helpful tool for assessing the overall quality of beverages adults consume. However, further studies are warranted to confirm the possible health effects of healthy beverage index.

• 한국컴퓨터정보학회논문지
• /
• 제17권1호
• /
• pp.203-209
• /
• 2012

최근 무선방송 환경을 기반으로 하는 k-최근접(k-Nearest Neighbor) 질의처리가 활발히 연구되고 있다. 무선방송환경의 장점은 서버 내에 존재하는 불특정 다수에게 일괄적으로 질의처리를 할 수 있는 확장성을 가진다는 것이다. 그러나 기존의 k-NN 질의는 무선방송환경에 적용할 경우 탐색과정에서 백트래킹이 발생하여 질의처리시간이 증가하는 단점을 가진다. 본 논문은 무선방송환경에서 k-NN 질의를 효과적으로 처리하기 위하여 계층적 비트맵 기반 공간색인(Hierarchical Bitmap-based Spatial Index: HBI)을 제안한다. HBI는 비트맵 정보와 트리 구조를 이용하여 비트맵의 크기를 줄인다. 결과적으로 방송주기를 줄임으로써 클라이언트의 청취시간과 질의처리 시간을 줄일 수 있다. 또한 비트맵 정보를 활용하여 객체의 위치를 모두 파악할 수 있기 때문에 필요한 데이터를 선택적으로 청취할 수 있다. 본 논문에서는 HBI를 k-NN 질의에 적용하여 실험을 실시하고 성능평가에서 제안 기법이 우수함을 증명한다.

• Journal of Preventive Medicine and Public Health
• /
• 제35권3호
• /
• pp.229-235
• /
• 2002

Objectives : To evaluate the effects on the formation of benzidine-hemoglobin, and benzidine metabolite-hemoglobin adducts, caused by pretreatment with the known xenobiotic metabolism effectors, ethanol and phenobarbital, in rats administered Direct Black 38 dye. Methods : The experimental rats were divided into three groups: a control group, an ethanol group and a phenobarbital group. Rats were pretreated with ethanol (1g/kg) or phenobarbital (80mg/kg) 24 hours prior to the oral administration of Direct Black 38 (0.5mmol/kg), with the control group being administered the same amount of distilled water. Blood samples were obtained from the vena cava of 5 rats from each group prior to, and at 30 min, 3h, 5h, 9h, 12h, 24h, 48h, 72h, 96h, and 144h following the oral administration of Direct Black 38. Directly after sampling the blood was separated into hemoglobin and plasma, with the adducts being converted into aromatic amines by basic hydrolysis. Hydrolyzed benzidiene, monoacetylbenzidine and 4-aminobiphenyl were analyzed by reverse-phase liquid chromatography with an electrochemical detector, The quantitative amount of the metabolites was expressed by the hemoglobin binding index (HBI). Results : In the ethanol group, benzidine-, monoacetylbenzidine-, and 4-aminobiphenyl-HBI were increased to a greater extent than those in the control group. These results were attributed to the ethanol inducing N-hydrgxylation, which is related to the formation of the hemoglobin adduct, In the phenobarbital group, all the HBIs, with the exception of the benzidine-HBI, were increased to a greater extent than those of the control group. These results were attributed to the phenobarbital inducing N-hydroxylation related to the formation of the hemoglobin adduct. The N-acetylation ratio was only increased with the phenobarbital pretreatment due to the lower benzidine-HBI of the phenobarbital group compared to these of the control and ethanol groups. The N-acetylation ratios for all groups were higher than f for the duration of the experimental period. Although the azo reduction was unaffected by the ethanol, it was inhibited by the phenobarbital, The ratio of the benzidine-HBI in the phenobarbital group was lower than those of the ethanol the control groups for the entire experiment. Conclusion : Our results indicate that both ethanol and phenobarbital increase the formation of adducts by the induction of N-hydroxylation, but also induced N-acetylation. Phenobarbital decreased the formation of benzidine-HBI due to the decrease of the azo reduction. These results suggest that the effects or ethanol and phenobarbital need to be considered in the biochemical monitoring of Direct Black 38.

• 대한의용생체공학회:의공학회지
• /
• 제35권4호
• /
• pp.95-98
• /
• 2014

The baroreflex is one kind of homeostatic mechanisms to regulate acute blood pressure (BP) changes by controlling heartbeat interval (HBI). To quantify the effect of baroreflex, we suggested a new approach of analyzing Granger causality between systolic BP (SBP) and HBI. The index defined as baroreflex effectiveness (BRE) was generated by the hypothesis that more effectual baroreflex would be related to more effective Granger causal influence of SBP on HBI. Six obstructive sleep apnea (OSA) patients (apnea-hypopnea index, AHI ${\geq}5$ events/hr) and six normal subjects participated in the study. Their SBP and HBI during nocturnal sleep were obtained from a non-invasive continuous BP measurement device. While the BRE ($mean{\pm}SD$) of normal subjects was $47.0{\pm}4.0%$, OSA patients exhibited the BRE of $34.0{\pm}3.8%$. The impaired baroreflex function of OSA patients can be explained by the physiological mechanism associated with recurrent hypoxic episodes during sleep. Thus, the significantly lower BRE in OSA patients verified the availability of Granger causality analysis to evaluate baroreflex during sleep. Furthermore, the range of BRE obtained from normal subjects was not overlapped with that obtained from OSA patients. It suggests the potential of BRE as a new helpful tool for diagnosing OSA.

• 한국의학물리학회지:의학물리
• /
• 제12권2호
• /
• pp.147-153
• /
• 2001

방사선 전신 및 반신 조사방법을 방사선치료에 적용하여 균일한 선량 분포를 유도하고자 조사거리에서 선량측정, 조직결손에 따른 보상과 선량 보정 방법을 논의하였다. 의료용 선형가속기에서 발생된 6MV 광자선을 이용한 전신 조사시의 흡수선량을 결정하는, 선원과 조사면사이의 거리 변화에 따른 계산자료를 조사면의 중심축에서 고체 팬톰, RFA-7 물팬톰(Scanditronix, Sweden)에 대해 UNIDOS 전리함(PTW, Germany), THERADOS 전리함(Scanditronix, Sweden)을 이용한 측정으로 그 크기를 결정하였다. 조직보상체는 연판과 아크릴판을 이용하였다. 전신조사의 조건은 선원으로부터 380 cm의 거리에서 120 $\times$ 120 $cm^2$ ～ 152 $\times$ 152 $cm^2$ 의 조사면을 대상으로 하였다. 전신조사를 위한 기본 자료 측정에서 선원과 조사면의 거리 변화에 따른 흡수 선량 분포는 거리가 멀수록 더 증가하는 현상을 보였고, 조사면의 모서리부분은 약 10-20% 의 선량이 감소되었으나 굴곡좌위형 체위를 취함으로서 선량분포를 보완할 수 있었다. 연판과 아크릴판을 이용한 조직결손에 따른 보상체 제작으로 중심축 선량비를 $\pm$ 8% 이내로 감소시킬 수 있었다. 조직결손의 보상에 따른 선량계산을 고찰하여 임상 적용시 선량분포의 불균일성을 줄일 수 있었다.

• Journal of Advanced Marine Engineering and Technology
• /
• 제29권7호
• /
• pp.744-749
• /
• 2005

This paper describes the performance improvement of power control system of magnetron (MGT) for microwave oven. The MGT is used extensively in household microwave oven and industrial microwave heating devices, and is operated by 3.0[kV] $\∼$5.0[kV] dc high voltage. The proposed power supply is consisted of a bridge rectifier, step-up converter(SUC) and its controller, half bridge inverter(HBI) and its controller, and full wave double voltage rectifier(DVR). In the proposed system, a good power factor can be obtained by the SUC' switching method that the inductor current waveforms follows that of the rectified voltage, and a line input power can be controlled to a range of 17.5[$\%$] by duty ratio (DR) adjustment of the HBI.

• 전기학회논문지P
• /
• 제54권4호
• /
• pp.179-184
• /
• 2005

This paper examines the application of high voltage static var compensator(SVC) with cascade multilevel inverter which employs H-bridge inverter(HBI). A new switching scheme is developed for the SVC system. To improve the unbalanced problem of the DC capacitor voltages, the rotated switching scheme of fundamental frequency is newly used. The optimized fundamental switching pattern with low switching frequency is adapted to be suitable for high application. The selective harmonic elimination method(SHEM) allows to keep the total harmonic distortion(THD) low in the output voltage of multilevel inverter. The SVC system is modeled using the d-q transform which calculates the instantaneous reactive power. This model is used to design a controller and analyze the SVC system. Simulated and experimental results are also presented and discussed to validate the proposed schemes.

• 전력전자학회:학술대회논문집
• /
• 전력전자학회 2013년도 전력전자학술대회 논문집
• /
• pp.534-535
• /
• 2013

본 논문은 당사에서 개발한 5Mvar급 STATCOM(static synchronous compensator)의 제어 시스템에 대해 기술한다. 제작된 5Mvar급 STATCOM은 한 상당 12대의 HBI(H-Bridge Inverter)로 구성이 가능하도록 25-Level로 제작되었다. 제안된 제어시스템은 DSP(digital signal processor)를 이용하였으며, 하나의 Main Controller와 다수의 Cell Controller, FPGA 보드 등으로 구성되어 있다. Controller 간의 상호 정보를 교환하기 위해 eCAN 통신을 이용하였고, HBI의 스위칭을 위한 보드는 각각에 연결되어 있으며, Cell Controller보드와는 절연을 위해 광신호로 연결하였다. 본 논문에서는 개발한 제어시스템의 신뢰성을 검증하기 위한 실험을 진행하였다.

• 한국산업보건학회지
• /
• 제11권2호
• /
• pp.118-125
• /
• 2001

Recently, biochemical analysis using hemoglobin adduct is frequently performed to evaluate the exposure to chemical carcinogens. However, data on the effect of co-exposure with other chemicals on hemoglobin adduct formation are seldom provided. The objective of this study is to evaluate the effects of pretreatment of ethanol(EtOH) and phenobarbital(PB), which are known to affect metabolism of xenobiotics, on the formation of hemoglobin adducts in the rats(Sprague-Dawley) administered benzidine(BZ). The experimental rats were divided into control, EtOH, and P8 groups. Rats were pretreated with EtOH or PB 24 hours before the oral administration of BZ. Blood sampling was taken before the administration of the chemicals and 0.5, 3, 6, 9, 12, 24, 48, 72, 96, and 144 hours after the administration of the BZ in 5 rats each. The blood was separated into hemoglobin and plasma immediately after taking the blood samples, and the adducts were undergone basic hydrolysis to convert them into aromatic amines. Hydrolyzed BZ, monoacetylbenzidine (MABZ), and 4-aminobiphenyl(4ABP) were separated by reversed-phase liquid chromatography without derivatization, and quantitative analyses of them were performed by a highperformance liquid chromatograph equipped with electrochemical detector. The quantitative amount of the metabolites was expressed by hemoglobin binding index(HBI), BZ-, MABZ-, and 4ABP-HBI of EtOH and PB groups were increased more than those of control group. These results are attributable to the fact that EtOH and PB induced N-hydroxylation related to the hemoglobin adduct formation. The ratio of N-acetylation (viz, MABZ-HBI/BZ-HBI) showed no significant difference between EtOH group and control group. It means that EtOH increased N-hydroxylation and N-acetylation in a similar degree. The N-acetylation ratio of PB group was relatively lower than control group because the PB increased N-hydroxylation induction. The N-acetylation ratios of all groups were higher than 1 during the entire experimental period. This result suggests that the effects of EtOH or PB need to be considered in the biochemical monitoring for the assessment of intermittent exposure of benzidine.

• 인터넷정보학회논문지
• /
• 제12권6호
• /
• pp.43-51
• /
• 2011

최근 무선 이동 컴퓨팅 기술과 위치기반 서비스 응용기술 등의 발전으로 과거보다 신속한 질의 처리를 지원할 수 있게 되었다. 그러나 여전히 하드웨어 및 소프트웨어의 기술적 한계가 존재한다. 질의 처리에 있어 가장 중요한 부분은 정확성과 신속성이다. 정확성을 높이기 위해서는 데이터에 상세한 정보를 저장해야 한다. 이 경우 데이터의 정보량이 증가하여 신속성이 떨어지게 된다. 반면에, 신속성을 높이기 위해서는 방송 주기를 줄여야만 얻고자 하는 데이터를 신속하게 얻게 된다. 이 경우 색인 정보의 부족으로 클라이언트의 청취 시간이 증가하여 불필요한 에너지 소모가 발생할 수 있다. 이와 같이, 정확성과 신속성 사이에는 트레이드 오프(trade-off)가 발생한다. 본 논문은 위와 같은 문제점을 극복하기 위해 계층적 비트맵 기반 공간 색인(Hierarchical Bitmap-based Spatial Index: HBI)을 제안한다. 계층적 비트맵 기반 공간 색인은 힐버트 커브(Hilbert Curve) 맵(map) 내에서 객체를 비트(0, 1)로 표기한다. 계층적 비트맵 기반 공간 색인은 비트 정보와 트리 구조를 이용하여 색인크기를 줄이는 방법으로 방송 주기를 줄임으로써 청취 시간과 질의 처리시간을 줄일 수 있다. 또한 계층적 비트맵 기반 공간 색인은 객체의 위치를 모두 파악할 수 있기 때문에 선택적인 청취가 가능하다. 성능평가를 통하여 제안 기법의 우수함을 증명한다.