• Title/Summary/Keyword: HBI

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The Association Between Healthy Beverage Index (HBI) With Metabolic Risk Factors Among Apparently Metabolically Healthy Overweight and Obese Individuals

  • Leila Jahanbazi;Mahdieh Abbasalizad Farhangi;Ayda Zahiri Tousi;Negin Nikrad
    • Clinical Nutrition Research
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    • v.12 no.3
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    • pp.218-228
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    • 2023
  • Recent studies have evaluated the association between specific beverage intake and metabolic risks in adults. However, more evidence is needed to examine the association between the Healthy Beverage Index (HBI) and metabolic factors. Therefore, this study investigated the relationship between HBI and metabolic factors in adults. In this cross-sectional study, 338 overweight and obese individuals living in Tabriz, Iran were selected. Data on beverage consumption, demographics, physical activity, and anthropometric characteristics were evaluated using validated standard protocols. The predefined HBI was calculated based on previous studies. The mean value of HBI index among all of the participants was 59.76 ± 6.51. Those at the higher HBI scores had significantly lower waist circumference, waist-to-hip ratio, fat mass, and weight (p < 0.05). HBI and triglyceride scores also had a significant relationship. It has been shown that at higher HBI scores compared to lower scores, high-density lipoprotein cholesterol levels increase while homeostatic model assessment for insulin resistance, low-density lipoprotein cholesterol, total cholesterol, and blood pressure decrease. HBI scores higher among Iranian adults were associated with a better chance of losing weight and weight loss and a better lipid profile, and lower blood pressure. Therefore, HBI can be a useful and helpful tool for assessing the overall quality of beverages adults consume. However, further studies are warranted to confirm the possible health effects of healthy beverage index.

A Hierarchical Bitmap-based Spatial Index use k-Nearest Neighbor Query Processing on the Wireless Broadcast Environment (무선방송환경에서 계층적 비트맵 기반 공간 색인을 이용한 k-최근접 질의처리)

  • Song, Doo-Hee;Park, Kwang-Jin
    • Journal of the Korea Society of Computer and Information
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    • v.17 no.1
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    • pp.203-209
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    • 2012
  • Recently, k-nearest neighbors query methods based on wireless broadcasting environment are actively studied. The advantage of wireless broadcasting environment is the scalability that enables collective query processing for unspecified users connected to the server. However, in case existing k-NN query is applied in wireless broadcasting environment, there can be a disadvantage that backtracking may occur and consequently the query processing time is increasing. In this paper proposes a hierarchical bitmap-based spatial index in order to efficiently process the k-NN queries in wireless broadcasting environment. HBI reduces the bitmap size using such bitmap information and tree structure. As a result, reducing the broadcast cycle can reduce the client's tuning time and query processing time. In addition, since the locations of all the objects can be detected using bitmap information, it is possible to tune to necessary data selectively. For this paper, a test was conducted implementing HBI to k-NN query and the proposed technique was proved to be excellent by a performance evaluation.

Effects of Ethanol and Phenobarbital on Hemoglobin Adducts Formation in Rats Exposed to Direct Black 38 (Direct Black 38 염료를 흰쥐에 투여 시 형성되는 헤모글로빈 부가체에 에탄올과 Phenobarbital이 미치는 영향)

  • Kim, Chi-Nyon;Lee, Se-Hoon;Roh, Jae-Hoon
    • Journal of Preventive Medicine and Public Health
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    • v.35 no.3
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    • pp.229-235
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    • 2002
  • Objectives : To evaluate the effects on the formation of benzidine-hemoglobin, and benzidine metabolite-hemoglobin adducts, caused by pretreatment with the known xenobiotic metabolism effectors, ethanol and phenobarbital, in rats administered Direct Black 38 dye. Methods : The experimental rats were divided into three groups: a control group, an ethanol group and a phenobarbital group. Rats were pretreated with ethanol (1g/kg) or phenobarbital (80mg/kg) 24 hours prior to the oral administration of Direct Black 38 (0.5mmol/kg), with the control group being administered the same amount of distilled water. Blood samples were obtained from the vena cava of 5 rats from each group prior to, and at 30 min, 3h, 5h, 9h, 12h, 24h, 48h, 72h, 96h, and 144h following the oral administration of Direct Black 38. Directly after sampling the blood was separated into hemoglobin and plasma, with the adducts being converted into aromatic amines by basic hydrolysis. Hydrolyzed benzidiene, monoacetylbenzidine and 4-aminobiphenyl were analyzed by reverse-phase liquid chromatography with an electrochemical detector, The quantitative amount of the metabolites was expressed by the hemoglobin binding index (HBI). Results : In the ethanol group, benzidine-, monoacetylbenzidine-, and 4-aminobiphenyl-HBI were increased to a greater extent than those in the control group. These results were attributed to the ethanol inducing N-hydrgxylation, which is related to the formation of the hemoglobin adduct, In the phenobarbital group, all the HBIs, with the exception of the benzidine-HBI, were increased to a greater extent than those of the control group. These results were attributed to the phenobarbital inducing N-hydroxylation related to the formation of the hemoglobin adduct. The N-acetylation ratio was only increased with the phenobarbital pretreatment due to the lower benzidine-HBI of the phenobarbital group compared to these of the control and ethanol groups. The N-acetylation ratios for all groups were higher than f for the duration of the experimental period. Although the azo reduction was unaffected by the ethanol, it was inhibited by the phenobarbital, The ratio of the benzidine-HBI in the phenobarbital group was lower than those of the ethanol the control groups for the entire experiment. Conclusion : Our results indicate that both ethanol and phenobarbital increase the formation of adducts by the induction of N-hydroxylation, but also induced N-acetylation. Phenobarbital decreased the formation of benzidine-HBI due to the decrease of the azo reduction. These results suggest that the effects or ethanol and phenobarbital need to be considered in the biochemical monitoring of Direct Black 38.

Evaluation of Baroreflex Effectiveness in Normal Subject and Obstructive Sleep Apnea Patient during Sleep using Granger Causality Analysis (그레인저 인과성 분석을 이용한 정상인과 수면무호흡증 환자의 수면 중 압수용기 반사 효과의 평가)

  • Jung, Da Woon;Kim, Sang Kyong;Kim, Ko Keun;Lee, Yu-Jin;Jeong, Do-Un;Park, Kwang Suk
    • Journal of Biomedical Engineering Research
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    • v.35 no.4
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    • pp.95-98
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    • 2014
  • The baroreflex is one kind of homeostatic mechanisms to regulate acute blood pressure (BP) changes by controlling heartbeat interval (HBI). To quantify the effect of baroreflex, we suggested a new approach of analyzing Granger causality between systolic BP (SBP) and HBI. The index defined as baroreflex effectiveness (BRE) was generated by the hypothesis that more effectual baroreflex would be related to more effective Granger causal influence of SBP on HBI. Six obstructive sleep apnea (OSA) patients (apnea-hypopnea index, AHI ${\geq}5$ events/hr) and six normal subjects participated in the study. Their SBP and HBI during nocturnal sleep were obtained from a non-invasive continuous BP measurement device. While the BRE ($mean{\pm}SD$) of normal subjects was $47.0{\pm}4.0%$, OSA patients exhibited the BRE of $34.0{\pm}3.8%$. The impaired baroreflex function of OSA patients can be explained by the physiological mechanism associated with recurrent hypoxic episodes during sleep. Thus, the significantly lower BRE in OSA patients verified the availability of Granger causality analysis to evaluate baroreflex during sleep. Furthermore, the range of BRE obtained from normal subjects was not overlapped with that obtained from OSA patients. It suggests the potential of BRE as a new helpful tool for diagnosing OSA.

A study on the dose distribution for total-body & hemibody irradiation using clinical photon beams (광자선을 이용한 전신 및 반신조사의 선량분포에 관한 고찰)

  • 김진기;권형철;김정수;오영기;김기환;신교철;김정홍;박충기;정동혁
    • Progress in Medical Physics
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    • v.12 no.2
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    • pp.147-153
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    • 2001
  • We have discussed that the total body irradiation(TBI) dose distribution of 6 and 10 MV photon beams, also differences between calculation dose use of compensator sheet and measurements in humanoid phantom. Total body irradiation and hemi-body irradiation(HBI) can be effectively performed when uniformity of dose distribution is estabilished. The method of TBI and HBI dosimatry requires special considerations related to technique, long distance and very large field, machine parameter, patient positioning. TBI and HBI with megavoltage photon beams requires basic dosimatric data which have to be measured directly or derived from the standard beam data. The semiconductor detector and ion chamber were positioned at a dmax depth, mid depth, and its specific ratio was determined using a scanning data by RFA-7 3-dimensional water phantom and solid phantom. The effective source axis distance 380 cm, the field size from 120 cm to 152 cm, isodose distributions were analyzed as a function of the thickness in phantom. Also, have discussed that the measurement of basic data for clinical photon beams for dosage calculations, data calculation sheet and the use of tissue compensation to improve dose uniformity. We have improved a dose uniformity in the TBI and HBI method.

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Performance Improvement of Power Control System for Driving MGT

  • Lee Sung-Geun
    • Journal of Advanced Marine Engineering and Technology
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    • v.29 no.7
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    • pp.744-749
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    • 2005
  • This paper describes the performance improvement of power control system of magnetron (MGT) for microwave oven. The MGT is used extensively in household microwave oven and industrial microwave heating devices, and is operated by 3.0[kV] $\∼$5.0[kV] dc high voltage. The proposed power supply is consisted of a bridge rectifier, step-up converter(SUC) and its controller, half bridge inverter(HBI) and its controller, and full wave double voltage rectifier(DVR). In the proposed system, a good power factor can be obtained by the SUC' switching method that the inductor current waveforms follows that of the rectified voltage, and a line input power can be controlled to a range of 17.5[$\%$] by duty ratio (DR) adjustment of the HBI.

A New Control Scheme for Maintaining Balanced DC Voltages in Static Var Compensator(SVC) Using Cascade Multilevel Inverter (직렬형 멀티레벨 인버터를 사용한 무효전력보상장치의 직류전압평형을 위한 새로운 제어기법)

  • Min, Wan-Ki;Min, Joon-Ki;Choi, Jae-Ho
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.54 no.4
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    • pp.179-184
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    • 2005
  • This paper examines the application of high voltage static var compensator(SVC) with cascade multilevel inverter which employs H-bridge inverter(HBI). A new switching scheme is developed for the SVC system. To improve the unbalanced problem of the DC capacitor voltages, the rotated switching scheme of fundamental frequency is newly used. The optimized fundamental switching pattern with low switching frequency is adapted to be suitable for high application. The selective harmonic elimination method(SHEM) allows to keep the total harmonic distortion(THD) low in the output voltage of multilevel inverter. The SVC system is modeled using the d-q transform which calculates the instantaneous reactive power. This model is used to design a controller and analyze the SVC system. Simulated and experimental results are also presented and discussed to validate the proposed schemes.

Design of the Control System for STATCOM (STATCOM용 제어시스템 개발)

  • Lee, Jong-Hak;Kim, Yun-Hyun;Kim, Tae-Hyeong;Kwon, Byung-Ki
    • Proceedings of the KIPE Conference
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    • 2013.07a
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    • pp.534-535
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    • 2013
  • 본 논문은 당사에서 개발한 5Mvar급 STATCOM(static synchronous compensator)의 제어 시스템에 대해 기술한다. 제작된 5Mvar급 STATCOM은 한 상당 12대의 HBI(H-Bridge Inverter)로 구성이 가능하도록 25-Level로 제작되었다. 제안된 제어시스템은 DSP(digital signal processor)를 이용하였으며, 하나의 Main Controller와 다수의 Cell Controller, FPGA 보드 등으로 구성되어 있다. Controller 간의 상호 정보를 교환하기 위해 eCAN 통신을 이용하였고, HBI의 스위칭을 위한 보드는 각각에 연결되어 있으며, Cell Controller보드와는 절연을 위해 광신호로 연결하였다. 본 논문에서는 개발한 제어시스템의 신뢰성을 검증하기 위한 실험을 진행하였다.

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Effects of ethanol and phenobarbital on hemoglobin adducts formation in rats exposed to benzidine (흰쥐에서 에탄올과 phenobarbital이 벤지딘의 헤모글로빈 부가체 형성에 미치는 영향)

  • Kim, Chi Nyon;Lee, Se Hoon;Kim, Hyun-Soo;Youn, Young-Shik;Roh, Jaehoon
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.11 no.2
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    • pp.118-125
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    • 2001
  • Recently, biochemical analysis using hemoglobin adduct is frequently performed to evaluate the exposure to chemical carcinogens. However, data on the effect of co-exposure with other chemicals on hemoglobin adduct formation are seldom provided. The objective of this study is to evaluate the effects of pretreatment of ethanol(EtOH) and phenobarbital(PB), which are known to affect metabolism of xenobiotics, on the formation of hemoglobin adducts in the rats(Sprague-Dawley) administered benzidine(BZ). The experimental rats were divided into control, EtOH, and P8 groups. Rats were pretreated with EtOH or PB 24 hours before the oral administration of BZ. Blood sampling was taken before the administration of the chemicals and 0.5, 3, 6, 9, 12, 24, 48, 72, 96, and 144 hours after the administration of the BZ in 5 rats each. The blood was separated into hemoglobin and plasma immediately after taking the blood samples, and the adducts were undergone basic hydrolysis to convert them into aromatic amines. Hydrolyzed BZ, monoacetylbenzidine (MABZ), and 4-aminobiphenyl(4ABP) were separated by reversed-phase liquid chromatography without derivatization, and quantitative analyses of them were performed by a highperformance liquid chromatograph equipped with electrochemical detector. The quantitative amount of the metabolites was expressed by hemoglobin binding index(HBI), BZ-, MABZ-, and 4ABP-HBI of EtOH and PB groups were increased more than those of control group. These results are attributable to the fact that EtOH and PB induced N-hydroxylation related to the hemoglobin adduct formation. The ratio of N-acetylation (viz, MABZ-HBI/BZ-HBI) showed no significant difference between EtOH group and control group. It means that EtOH increased N-hydroxylation and N-acetylation in a similar degree. The N-acetylation ratio of PB group was relatively lower than control group because the PB increased N-hydroxylation induction. The N-acetylation ratios of all groups were higher than 1 during the entire experimental period. This result suggests that the effects of EtOH or PB need to be considered in the biochemical monitoring for the assessment of intermittent exposure of benzidine.

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A Hierarchical Bitmap-based Spatial Index for Efficient Spatial Query Processing on Air (무선환경에서 효과적인 공간질의 처리를 위한 계층적 비트맵 기반 공간 색인)

  • Song, Doo-Hee;Park, Kwang-Jin
    • Journal of Internet Computing and Services
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    • v.12 no.6
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    • pp.43-51
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    • 2011
  • The recent development of the technology for wireless mobile computing and applied technology for location-based services has made it possible to support query processing faster than that in the past. However, some technological limitations on hardware and software still exist. The most critical aspects of query processing are accuracy and speed. For improving the accuracy, it is required that detailed information on the data involved in query processing be saved. In this case, the amount of information on the data increases, which decreases the speed. On the other hand, for increasing the speed, it is necessary to reduce the broadcast cycle, which enables rapid data acquisition as desired. In this case, because of insufficient index information, the listen time for the client increases, which may cause unnecessary energy consumption. Therefore, a trade-off occurs between the accuracy and speed. This paper proposes a hierarchical bitmap-based spatial index (HBI) as a solution for the aforementioned problems. HBI describes an object with 0 and 1 on the Hilbert curve map. It reduces the broadcast cycle by decreasing the index size on the basis of bit information and tree structure. Therefore, it is able to shorten the listen time and query processing time. In addition, HBI enables the detection of the locations of all the objects so that it is possible selectively listen to a broadcast. A performance evaluation of the proposed technique demonstrates that it is excellent.