• 대한한방부인과학회지
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• 제21권1호
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• pp.117-133
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• 2008

Purpose: This study was performed to evaluate anti-thrombotic effects of Hyulbuchukeotanggamibang(HBCT). Methods: It was measured the effects which was given to blood flow rate through the regular volume of glass tube after the blood was diluted five times with ACD soulution. Antithrombotic effect was calculated as a percentage of the experimental animal figure protected from the paralysis of hind legs or death of the mouse that is caused from the administration of platelet aggregation regent. Results: 1. HBCT showed a safety in toxicity of liver. 2. In experiment of anti-thrombotic effect, HBCT inhibited the platelet aggregation induced by ADP and epinephrine, collagen, arachidonic acid as compared with the control group. 3. HBCT inhibited pulmonary embolism induced by collagen and epinephrine (inhibitory rate is 50%). 4. HBCT increased platelet number and fibrinogen amount significantly and also HBCT shortened PT and APTT significantly as compared with the control group in thrombus model induced by dextran. 5. HBCT increased blood flow rate insignificantly as compared with the control group in vivo. Conclusion: These results suggest that HBCT can be used for treating diverse female diseases caused by thrombosis.

• 대한한방부인과학회지
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• 제21권1호
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• pp.99-116
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• 2008

Purpose: This study was performed to evaluate anti-inflammatory effects of Hyulbuchukeotanggamibang water extract (HBCT). Methods: In the study of anti-inflammatory effects, HBCT was investigated using cultured cells and a murine models. As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators which are known to be related to inflammation were determined in mouse lung fibroblast cells (mLFCs) and RAW264.7 cells. Results: Prior to the experiment, we investigated the cytotoxicity of HBCT. HBCT showed a safety in cytotoxicity on mLFCs. In experiment of anti-inflammatory effect, HBCT effected scavenging activity on DPPH free radical, superoxide dismutase and superoxide anion radical. HBCT inhibited $IL-1{\beta}$, IL-6, $TNF-{\alpha}$, COX-2 and NOS-II mRNA expression in a concentration-dependent manner in RAW264.7 cell line, and inhibited significantly $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ production at $100{\mu}g/\;ml$ in a concentration-dependent manner. Conclusion: These results suggest that HBCT can be used for treating diverse female diseases caused by inflammation such as endometriosis, pelvic pain, cervicitis, pelvic inflammatory disease and pelvic tuberculosis and so forth.

• 한국항만경제학회지
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• 제28권2호
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• pp.179-194
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• 2012

본 연구는 컨테이너터미널의 서비스 투입자원 중 장비를 중점으로 컨테이너터미널의 효율성 비교 평가하기 위해 DEA와 AHP 기법을 혼합한 AHP/DEA 통합모형을 적용하였다. 분석은 광양항(GICT, KEC, KIT), 부산항(HBCT, KBCT, DPCT, UTC, 감만부두) 그리고 부산신항(PNC, PNIT, HJNC, HPNT)의 12개 운영사를 대상으로 하였다. 제안된 AHP/DEA 통합모형은 DEA 모형의 가중치간의 불균형으로 인하여 잘못 평가된 DMU 발생가능성과 효율적인 DMU간의 우열에 대한 변별의 어려움을 극복하기 위해 DEA-AR(Assurance Region)모형을 적용하였고, DEA-AR모형의 가중치 범위를 산출하기 위해 전문가의 의견을 객관적인 가중치로 변환할 수 있는 AHP(Analytic Hierarchy Process) 방법론을 사용하였다. 연구모형의 투입변수는 C/C 수, TC 수, YT 수, RS 수로 하였고 산출변수는 컨테이너 물동량으로 하였다. 연구결과 AHP/DEA 통합모형은 기존의 항만 및 컨테이너터미널의 효율성 평가에 사용되었던 DEA, 또는 DEA 응용모형에 비해 최고의 효율성을 가지는 컨테이너터미널을 선정에 있어 유연하고, 우수한 능력이 있음을 분석결과의 비교를 통해 알 수 있었다. 분석결과를 보면 하역장비 효율성이 100%로 달성한 터미널은 DPCT로 나타났고, 상대적으로 부산항 터미널들의 장비 효율성이 높은 것으로 분석되었다.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2002년도 춘계학술대회논문집
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• pp.189-196
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• 2002

As the quantity of transported goods increases, there is a lot of mechanical trouble with loading facilities. So it tremendously produces not only economic loss but also time loss. To reduce the loss from the trouble of leading facilities, it is necessary to analyse the distribution of the problem's occurrence and use the analyzed data to minimize the outbreak of trouble. So the data can be usefully used when designing or manufacturing and it also can be utilized for proper maintenance of operating equipment, frequency of inspection and repair, know-how of checking on equipment and purchasing of spare parts. And it is possible to minimize the loss if the propel maintenance is adapted

• 대한한방부인과학회지
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• 제27권1호
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• pp.152-166
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• 2014

Purpose: The purpose of this study is to compare with the result of experimental study about antithrombotic effect by reviewing recent oriental medicine journals that have been published since 2001' in Korea. Methods: Articles on antithrombotic effect that have been published from 2001' to 2013' in oriental medicine journals registered National Research Foundation of Korea were searched. After that, 12 articles using same 'thrombosis condition model' were selected and reviewed. Results: The results were as follows. 1. If there is no limit drug concentrations, platelet aggregation induced by adenosine diphosphate (ADP) in hyulbuchukeo-tanggamibang (HBCT) was the largest aggregation inhibitory effect and platelet aggregation induced by epinephrine in Saegeum-san (SGS), Jogan-tanggagambang (JGTG), hyulbuchukeo-tanggamibang (HBCT) had a large inhibitory effect on aggregation. 2. At the lowest concentration, Mokdan-san (MDS) of the inhibition of platelet aggregation induced by ADP and Hyunhosaik-san (HHS) of the inhibition of platelet aggregation induced by epinephrine were effective. 3. Pulmonary embolism induced by collagen and epinephrine in Neungasojeok-tang (NSJT) has the highest antithrombotic effect. 4. Pathological conditions of extravasated blood by dextran, Jogan-tanggagambang (JGTG) has the highest inhibitory effect on decrease in platelet numbers. Compared to the rest of the experimental drug, Saegeum-san (SGS), Heanggyonghonghwa-tang (HGTHHT), Wusl-san (WSS), Mokdan-san (MDS) showed significant inhibitory effect on the prothrombin time (PT) increases. Honghwadanggui-san (HDS), Saegeum-san (SGS) showed significant inhibitory effect on increase in activated partial thromboplastin time (APTT) and Jogan-tanggagambang (JGTG), Heanggyonghonghwa-tang (HGTHHT) showed significant inhibitory effect on decrease in fibrinogen. Conclusions: This result will provide useful information for the prescriptions of antithrombotic medicine in the field of Oriental medicine. We will have to carry out further studies that will compare each herb used in the diseases caused by extravasated blood.

• 한국항만경제학회지
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• 제27권4호
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• pp.187-205
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• 2011

우리나라 컨테이너 물동량 규모를 고려할 경우 실질적으로 허브포트는 부산항 one-port가 바람직하지만 이미 부산항과 광양항을 two-port로 개발하고 있기 때문에 메가 허브 포트는 부산항과 광양항으로 충분할 것이다. 인천항 등 다른 지역항만을 추가로 개발할 경우 메가 허브 포트로 발전하기 보다는 피더포트로 전략할 가능성이 높다. 또한 수도권 물동량은 인천항과 평택항을 이용하므로 컨테이너 터미널 운영사간의 시설과잉에 따른 출혈경쟁이 야기되어 수익성 보장이 쉽지 않다. 따라서 인천항과 평택항 등 지역항만을 개발하는 것보다는 한 중 일 근해항로 중심의 권역별 거점항만으로 개발하여 수도권 수출입 물동량을 집중 처리하는 것이 컨테이너 터미널 운영사의 수익성 제고차원에서 바람직할 것이다. 컨테이너터미널 운영사간 과열경쟁을 완화하기 위해 국내 항만과 경쟁관계에 있는 일본(고베, 도쿄)과 중국(상해, 청도, 천진, 대련)의 요율과 비교하여 적정선을 유지하도록 하는 행정적 지도도 필요하다. 본고는 광양항, 부산항, 인천항의 컨테이너 터미널 운영사를 대상으로 효율성을 분석한다. 2006년부터 2010년까지 5년간의 자료를 수집하여 분석에 사용하였다. 분석변수는 4개의 투입요소(안벽길이, 야드면적, 크레인수, 직원수)와 1개의 산출요소(총 화물처리량)를 이용하였다. 분석결과는 CCR모형에 의한 효율성 측정결과 2006년 통운광양, KIT, 감만부두, DPCT, 통운 남항, 2007년은 감만부두, DPCT, 통운남항, 2008년은 감만부두, DPCT, 통운남항, 2009년은 통운부산, DPCT, 통운남항, 2010년에는 통운부산, DPCT, 통운남항이 효율적인 컨테이너 터미널은 운영사로 분석되었다. BCC모형에 의한 효율성 측정결과 2006년 통운광양, KIT, 감만부두, DPCT, 통운남항이다. 2007년은 통운광양, 통운부산, 감만부두, DPCT, 통운남항, 통운 4부두, 2008년 통운광양, 통운부산, 감만부두, DPCT, 통우남항, 2009년은 통운부산, HBCT, 감만부두, DPCT, 통운남항, 2010년에는 통운광양, 통운부산, DPCT, 통운남항, 통운4부두, ICT가 효율적인 컨테이너 터미널로 분석되었다.