• Archives of Pharmacal Research
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• v.29 no.10
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• pp.890-897
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• 2006

In inflammatory responses, induction of cytokines and other immune regulator genes in macrophages by pathogen-associated signal such as lipopolysaccharide (LPS) plays a crucial role. In this study, the gene expression profile changes by LPS treatment in the macrophage/monocyte lineage cell line RAW264.7 was investigated. A 60-mer oligonucleotide microarray of which probes target 32381 mouse genes was used. A reverse transcription-in vitro translation labeling protocol and a chemileuminescence detection system were employed. The mRNA expression levels in RAW264.7 cells treated for 6 h with LPS and the control vehicle were compared. 747 genes were up-regulated and 523 genes were down-regulated by more than 2 folds. 320 genes showing more than 4-fold change by LPS treatment were further classified for the biological process, molecular function, and signaling pathway. The biological process categories that showed high number of increased genes include the immunity and defense, the nucleic acid metabolism, the protein metabolism and modification, and the signal transduction process. The chemokine-cytokine signaling, interleukin signaling, Toll receptor signaling, and apoptosis signaling pathways involved high number of genes differentially expressed in response to LPS. These expression profile data provide more comprehensive information on LPS-target genes in RAW264.7 cells, which will be useful in comparing gene expression changes induced by extracts and compounds from anti-inflammatory medicinal herbs.

• Journal of Broadcast Engineering
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• v.14 no.6
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• pp.749-768
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• 2009

In this paper, an intra prediction offset compensation method is proposed to improve intra prediction in H.264/AVC. In H.264/AVC, intra prediction based on various directions improves the coding efficiency by removing spatial correlation between neighboring blocks. In details, neighboring pixels in reconstructed block can be used as intra reference block for the current block to be coded when intra prediction method is used. In order to reduce further the prediction error of the intra reference block, the proposed method introduces an intra prediction offset which is determined in the sense of the rate-distortion optimization and is added to the conventional intra prediction block. Besides the intra prediction offset compensation, the coefficient thresholding method which is used for inter coding in JM 11.0, is used for chroma component in intra block, which leads the improvement of the luma coding efficiency of the proposed method. In experiments, we show that the proposed method achieves average 2.45% in High Profile condition and maximum 4.41% of bitrate reduction relative to JM 11.0.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2015.07a
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• pp.470-473
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• 2015

본 논문에서는 MPEG 에서 현재 Type-1 동영상 표준을 위해 연구를 진행하고 있는 인터넷 비디오 코딩(Internet Video Coding, IVC)의 압축 성능에 대한 평가 방법 및 결과를 다룬다. 다년간의 연구로 IVC 의 성능은 매우 개선되어 왔으나, 산업이 원하는 수준에 도달했는지를 검증하기 위해서는 타 동영상 코덱과의 비교 평가 역시 필요하다. 이를 위하여, AVC/H.264 를 기반으로 Type-1 표준화를 진행해온 Web Video Coding(WebVC)의 인코더와 IVC Test Model 10.0 을 압축 성능 관점에서 객관적으로 비교 평가함으로써, IVC 의 부호화 성능의 뛰어남을 보이고자 한다. 또한, 상용화된 AVC/H.264 High Profile 과도 비교함으로써, IVC 의 객관적인 성능을 확인하고자 한다. 특별히, MPEG 내에서 결정한 시각적 비교 조건(Visual comparison condition)에 입각한 목표 비트율 및 양자화 변수 조건에 맞추어 평가한다.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.45 no.11
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• pp.71-76
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• 2008

H.264(or MPEG-4/AVC pt.10) is a high performance video coding standard, and is widely used. Variable length code (VLC) of the H.264 standard compresses data using the statistical distribution of values. A decoder parses the compressed bit stream and searches decoded values in lookup tables, and the decoding process is not easy to implement by hardware. We propose an architecture of variable length decoder(VLD) for the H.264 baseline profile(BP) L4. The CAVLD decodes syntax elements using the combination of arithmetic units and lookup tables for the optimized hardware architecture. A barral shifter and a first 1's detector parse NAL bit stream, and are shared by Exp-Golomb decoder and CAVLD. A FIFO memory between CAVLD and the reorder unit and a buffer at the output of the reorder unit eliminate the bottleneck of data stream. The proposed VLD is designed using Verilog-HDL and is implemented using an FPGA. The synthesis result using a 0.18um standard CMOS technology shows that the gate count is 22,604 and the decoder can process HD($1920{\times}1080$) video at 120MHz.

• 유체기계공업학회:학술대회논문집
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• 1999.12a
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• pp.264-271
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• 1999

The present experimental study is aimed to investigate the flow characteristics of the high-speed flow field within hot-water pump by PIV(Particle Image Velocimetry). As multi-point simultaneous velocity acquisition, 2-D PIV system based upon the two-frame gray-level cross correlation method is adopted using PC frame-grabber and simple video system. Gated image intensifier CCD Camera to cope with illumination problem is arranged for accurate PIV measurement of high-speed complex flow. The velocity vector distribution, velocity profile, and kinetic energy are represented quantitatively at the full-scale region for the deeper understanding of the unsteady flow characteristics in a pump.

• Journal of Broadcast Engineering
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• v.21 no.3
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• pp.319-329
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• 2016

Internet Video Coding (IVC) is a royalty-free codec currently being developed in MPEG. Coding efficiency of IVC codec has been steadily enhanced and it was reported that the performance of Committee Draft (CD) version is comparable to H.264/AVC High Profile (HP) in terms of objective and subjective qualities. In this paper, we present some coding tools that have been proposed for enhancing the coding efficiency of IVC during the developing process in MPEG along with brief overview of IVC codec architecture and coding algorithms. The coding tools include both of normative tools and informative tools such as non-reference P frame coding, DC mode intra prediction, Lagrange multiplier selection, and extension of chroma intra prediction modes. Improvement obtained by each tool is presented in terms of algorithm and coding gain based on the experiments. As a result of the experiment, the coding tools give the average bit saving of 8.8%, 0.4%, 0.4%, and 0.0%, respectively, in the low-delay coding mode.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2010.07a
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• pp.294-296
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• 2010

일반적으로, RGB 영상의 높은 주파수 영역은 잡음으로 인해 색평면 간 서로 낮은 상관도를 가지고 있기 때문에 이러한 고주파수 성분은 색평면 간 예측의 효율을 저하시키는 원인이 된다. 본 논문에서는 RGB 비디오 코딩에서 색평면 간 예측의 효율을 높이기 위해 기저 색평면을 적응적으로 필터링 하는 방법을 제안한다. 색평면 간 상관도에 따라 적응적으로 기저 색평면을 필터링함으로써 색평면 간 예측 성능을 높일 수 있었다. 본 논문에서 제안하는 알고리즘을 통해 우리는 H.264/AVC High 4:4:4 Intra Profile에 비해 평균 14.71%의 비트율 감소와 0.93dB의 PSNR 향상 결과를 얻을 수 있었다.

• Smart Media Journal
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• v.3 no.4
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• pp.16-21
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• 2014

HEVC is the latest joint video coding standard with ITU-T SG16 WP and ISO/IEC JTC1/SC29/WG11. Its coding efficiency is about two times compared to H.264 high profile. Intra prediction has 35 directional modes including dc and planer. However an accurate mode decision on lots of modes with SSE is too costly to implement it with hardware. The key idea of this paper is a DCT shared architecture to reduce the complexity of HEVC intra encoder. It is to use same DCT block to quantize as well as to calculate SSE in RDO. The proposed intra encoder uses two step mode decision to lighten complexity with simplified RDO blocks and shares the transform resources. Its BD-rate increase is negligible at 20% on hardware aspect and the operating clock frequency is 300MHz@60fps on FHD ($1920{\times}1080$) image.