• Journal of Animal Science and Technology
• /
• v.62 no.6
• /
• pp.765-776
• /
• 2020

The retinal degenerative disease, progressive retinal atrophy (PRA) is a major reason of vision impairment in canine population. Canine PRA signifies an inherently dissimilar category of retinal dystrophies which has solid resemblances to human retinis pigmentosa. Even though much is known about the biology of PRA, the knowledge about the intricate connection among genetic loci, genes and pathways associated to this disease in dogs are still remain unknown. Therefore, we have performed a genome wide association study (GWAS) to identify susceptibility single nucleotide polymorphisms (SNPs) of PRA. The GWAS was performed using a case-control based association analysis method on PRA dataset of 129 dogs and 135,553 markers. Further, the gene-set and pathway analysis were conducted in this study. A total of 1,114 markers associations with PRA trait at p < 0.01 were extracted and mapped to 640 unique genes, and then selected significant (p < 0.05) enriched 35 gene ontology (GO) terms and 5 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways contain these genes. In particular, apoptosis process, homophilic cell adhesion, calcium ion binding, and endoplasmic reticulum GO terms as well as pathways related to focal adhesion, cyclic guanosine monophosphate)-protein kinase G signaling, and axon guidance were more likely associated to the PRA disease in dogs. These data could provide new insight for further research on identification of potential genes and causative pathways for PRA in dogs.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.21 no.1
• /
• pp.19-34
• /
• 1997

The goals of this study are to suggest the guidance for automated clothing manufacture by analysis the technology of the automated manufacturing facilities and to propose how improve the efficiency of the production planning and management for automated clothing manufacture In this study, the research about the automated clothing manufacturing machines and the analysis about the modules and functions of apparel information systems were performed. In order to understand the factory automation of the larger clothing firms, the case study method was used. The case study samples were 3 clothing firms. The results and suggestions are as follows: 1. An information technology for automated clothing manufacture has enabled the computer integrated manufacturing system to connect production planning and management part with each work station on the factory floor. 2. The apparel information system to integrate and manage manufacturing informations from each workstation and the apparel CAD system are used in the department of production planning. At the cutting room, there are automated manufacturing machines like an automatic spreading system and an automatic cutting system. Sewing room has the computer controlled unit production system and semi-automated sewing machines. In addition, in the finishing room, an automatic packing machine and a press system are used and besides a warehousing system has been developed. Considering these available technology, for better product efficiency, it is necessary to consider and utilize the specific character of these automatic manufacturing machines and computer system whether they proper to each product style. 3. Most of the clothing manufacturers are in the stage of semi-automated manufacture. In order to improve the manufacturing environment, it is needed to gradual procedure of manufacturing automation with considering the firm's financial condition, existing facilities and staffs operating machines. The case study sample firms are in the high degree of manufacturing automation. They can accomplish the flexible manufacturing system to link the information system with each work station menufacturing system by computerized control. For the case of the firm having already used the computer integrated manufacturing and managing system, it is necessary that the function to deal with drawing information is added to the retaining module of the apparel system.

• Journal of Veterinary Clinics
• /
• v.11 no.2
• /
• pp.507-516
• /
• 1994

The purposes of this investigations were survey of the occurred bacterial diseases, development of new animal health drug, guidance to formers on the treatment and control methods of diseases. Some series of investigations have been carried out by microbiological, pathological and serological examinations. The results could be summarized as follows. 1. A total of 953 cases of outbreaked swine diseases have been diagnosed in Clinical pathology laboratories, Bayer Vet Res Institute during 8 years (from 1986 to 1993). The high incidence diseases were colibacillosis, pleuropneumonia, streptococcal infection and pasteurellosis in decreasing order. 2. Pleuropneumonia caused by Actinobacillus pleuropneumoniae was the most important respiratory diseases and pasteurellosis by Pasteurella multocide could be confirmed in several cases. 3. Actinobacillus pleuropneumoniae 50 strains were isolated and identified by biochemical and serological tests. In serotyping test, 22 isolated strains were serotype 5, 21 strains as serotype 2, each 2 strains as serotype 3 and 7 by the coagglutination test. 4. Colibacillosis and edema discase caused by Escherichia coli has been the most predominant outbreaked disease in this investigations. The 100 isolates of E coli strains were sensitive to amikacin, colistin, enrofloxacin, gentamycin and trimethoprim -sulfamethoxazole. 5. Swine erysipelas caused by Erysipelothrix rhusiopathiae was confirmed 25 cases as acute septicemic forms. Isolates of E rhusiopathiae were highly sensitive to ampicillin, cephalothin, enrofloxcin, penicillin and tetracycline. 6. The 49 cases of hemorrhagic and necrotic enteritis in piglets were observed and 13 strains of Clostridium perfringens could be isolated and confirmed by biological and serological test. Isolates of Clostridium perfringens type C were highly sensitive to ampicillin, cephalothin, enrofloxacin, penicillin and trimethoprim- sulfamethoxazole. 7. The 14 strains of Streptococcus suis type II could be isolated from meningitis of piplets. 8. Polyserositis caused by Haemophilus parasuis and salmonellosis were observed and confirmed. Also Corynebacterial infections and several parasitosis have been also observed in this investigations.

• Korean Journal of Clinical Laboratory Science
• /
• v.50 no.2
• /
• pp.77-84
• /
• 2018

In Singapore, biosafety and biosecurity measures are controlled by the Biological Agents and Toxins Act (BATA) and other requirements by regulatory agencies. The law prohibits and otherwise regulates the possession, use, import, transhipment, transfer, and transportation of biological agents, inactivated biological agents, and toxins that are of public health concern. The law also defines the facility requirements for high risk biological agents and toxins. The containment facility (BSL 3) is a minimum requirement to handle biological agents that falls under Schedule 1 (Risk Group 3). The Nanyang Technological University School of Biological Sciences Biosafety Level 3 Facility (NTU-SBS BSL 3) was designed specifically for research involving potential hazardous biological materials. The facility requires yearly re-certification by an approved facility certifier to meet the local requirements and international biosafety standards for a containment facility in many instances. On the other hand, most NTU researchers conduct biological projects involving biological agents with low or moderate risk groups (Risk Groups 1 and 2 or biological agents described in schedule 3 and 4 of BATA) and GMOs, which need only a BSL 2 laboratory. BSL 2 laboratories are yet to be legally certified or registered in Singapore. Institutional Biosafety Committee (IBC) identifies the requirements; defines a minimum standard in the safe control of biological risks and registers all BSL 2 laboratories in the NTU. Therefore, under the guidance of the IBC, the University Biosafety and Biosecurity Programme includes the audit and certification program as a unique and an internal exercise to bring NTU biosafety to a higher level.

• Journal of Korean society of Dental Hygiene
• /
• v.21 no.3
• /
• pp.311-318
• /
• 2021

Objectives: The purpose of this study was to understand the level and patterns of college adjustment, major satisfaction, academic engagement, and attention deficit hyperactivity disorder (ADHD). This study examined the factors influencing adaptation to college life. Methods: This study was approved by the institutional review board of 00 university. We analyzed 166 survey data responses collected by distributing questionnaires from June 1 to July 2, 2020. Statistical product and service solutions version 23.0 was used for statistical analyses. The data were presented as frequencies and percentages or means and standard deviations, and pearson correlation analysis and multiple regression analysis were performed. Results: There was a significant difference in the average score of major satisfaction according to the type of college (university) and grades. For college adjustment, there was a significant difference in the average score according to major grades. Academic engagement showed a significant difference in the average score according to the college type and grade. Major satisfaction, college adjustment, and academic motivation showed significant positive correlations among the variables, whereas ADHD, major satisfaction, and college adjustment showed a significant negative correlation. Multiple regression analysis revealed that major satisfaction (p<0.001) and academic motivation (p<0.001) were factors affecting college adjustment (p<0.05). Conclusions: It is necessary to develop and apply specific and systematic adaptation programs to improve the understanding, control, and guidance methods for college students and to promote human relations, such as school life and social life.

• Korean Journal of Community Nutrition
• /
• v.3 no.2
• /
• pp.190-201
• /
• 1998

This study was carried out with 505(243 boys and 262 girls in the Sungnam area) high school students to investigate the effects of eating behavior and anthropometric variables of weight and height on excercise performance. General characteristics about subjects and eating behavior were surveyed by questionnaire, anthropometric data were collected using two methods. The weight and height of subjects in 1996 were measured, but the same data in 1995 were collected from health records of each student. Body fat content of subjects was measured by BIA(Body Impedance Analysis). The grades of exercise performance, which were evaluated by physical education teachers were collected from records of a physical strength test score of each subject. From these, the following result were found. Groups with different eating behaviors such as skipping meals, overeating, food preference for a specific food(milk, carbonated drink etc.) were significantly different in their weight and height and body fat contents. The growth rate of height in first and second grade boys was significantly higher than that for grade boys. The amount of weight gain from second grade to third grade was significantly more than that of other grades both for boys and girls. The mean of BMI was $21.66\pm{2.95}$ in boy, $21.50\pm{2.62}$ in girls. The percentage of body fat was $24.91\pm{6.55%}$ in boy $34.73\pm{4.88%}$ in girls. Amounts of body fat were significantly increased in third grade. The group with higher fat content and the higher BMI group had lower values of physical strength. And the ability to exercises perform decreased significantly by promotion of grade. The other variables such as degree of concern about weight control and preference of exercise, and frequencies of exercise per week were significant factors in body fat content and physical strength. As a countermeasure for these problems, nutrition and health education must be developed for adolescents and a practical, proper physical activity guidance campaign for them is necessary.

• Journal of Nutrition and Health
• /
• v.50 no.1
• /
• pp.53-63
• /
• 2017

Purpose: This study was performed to examine motivational factors affecting sweetness preference in Korean and Japanese children. We identified meaningful variables that could be targeted to nutrition education interventions designed to overcome innate barriers and reduce sweetness preference and sweet food intake in Korean and Japanese children. Methods: Questionnaire surveys and sweetness preference test were conducted to examine variables affecting behavioral intention (BI) regarding sweetness preference. Questionnaire variables were based on the theory of planned behavior. Participants were recruited from one urban school from each country. In total, 166 children (mean age: 8.4 years) and their guardians (n = 166) participated in the study. A trained research assistant provided all children with personal guidance regarding completion of the sweetness preference test and survey questionnaire at school. The data were analyzed using Pearson's correlation coefficients, t tests, repeated measure ANOVA, and stepwise multiple regression analysis (significance level: p < 0.05). Results: Perceived behavioral control (PBC) and parenting practice were significantly associated with BI in both groups. Motivation to comply affected BI only in Japanese children, whereas affective attitude was associated with BI only in Korean children. In predicting sweetness preference, BI was associated only in Japanese children, whereas sweets consumption frequency had a significant effect in Korean children. Conclusion: The study shows similarities and differences in motivational factors, which could be considered when developing nutrition education programs in Korea and Japan. PBC and parenting practice were common factors in predicting BI. In predicting sweetness preference, BI had a significant effect on Japanese children, whereas sweets consumption frequency was the greatest contributor in Korean children.

• Journal of Hydrogen and New Energy
• /
• v.30 no.5
• /
• pp.401-410
• /
• 2019

The operating conditions greatly impact the efficiency and performance of polymer electrolyte membrane (PEM) fuel cell systems and must be properly managed to ensure better performance and efficiency. In particular, small variations in operating conditions interact with each other and affect the performance and efficiency of PEM fuel cell systems. Thus, a systematic study is needed to understand how small changes in operating conditions affect the system performance and efficiency. In this paper, an automotive fuel cell system (including cell stack and balance of plant [BOP]) with a turbo-blower was modeled using MATLAB/Simulink platform and the sensitivity analyses of main operating parameters were performed using the developed system model. Effects of small variations in four main parameters (stack temperature, cathode air stoichiometry, cathode pressure, and cathode relative humidity) on the system efficiency were investigated. The results show that cathode pressure has the greatest potential impact on the sensitivity of fuel cell system efficiency. It is expected that this study can be used as a basic guidance to understand the importance of achieving accurate control of the fuel cell operating conditions for the robust operation of automotive PEM fuel cell systems.

• Food Science of Animal Resources
• /
• v.44 no.3
• /
• pp.651-661
• /
• 2024

Chicken broth has a taste of umami, and the stewing time has an important effect on the quality of chicken broth, but there are fewer studies on the control of the stewing time. Based on this, the study was conducted to analyze the effects of different stewing times on the sensory, small molecular metabolites, free fatty acids, and volatile flavor compounds contents in chicken broths by liquid chromatography-quadrupole/time-of-flight mass spectrometry, gas chromatography-mass spectrometry, headspace solid-phase microextraction, and gas chromatography-mass spectrometry. Eighty-nine small molecular metabolites, 15 free fatty acids, and 86 volatile flavor compounds were detected. Palmitic and stearic acids were the more abundant fatty acids, and aldehydes were the main volatile flavor compounds. The study found that chicken broth had the best sensory evaluation, the highest content of taste components, and the richest content of volatile flavor components when the stewing time was 2.5 h. This study investigated the effect of stewing time on the quality of chicken broth to provide scientific and theoretical guidance for developing and utilizing local chicken.

• Journal of the Korean Institute of Landscape Architecture
• /
• v.31 no.2
• /
• pp.28-35
• /
• 2003

This study was conducted to identify the characteristics of social carrying capacity at mega-events, especially the 2000 Kwangju Biennale in Korea. In particular, this paper has proposed some management policies for mega events taking into account the relations between social carrying capacity, satisfaction and crowding. The research method was to look into the general characteristics and distributive forms of the location, and then to confirm the possibility of sampling the factors involved in satisfaction degree; last, A factor analysis for causal analysis of perceived crowding was performed. The study needed correlation analysis in order to compare expected crowding and perceived crowding, and performed regression to examine the causality of perceived crowding and satisfaction. The research results were as follows: the correlation of expected crowding, perceived crowding, and the total satisfaction was very low or meaningless. The relation between satisfaction and elements for factor analysis such as convenient facilities and value experience showed partial meaningfulness. The factors of convenient facilities, entrance fee, parking lot use, toilet convenience, and exhibit room use had meaningful results; on the other hand, the factors of value experience showed a meaningful result in the guide service of an event place. In conclusion when those holding an event make a basic project, they should consider management measures for convenience of facilities, proper education for guide service, and systematic guidance. Also, as a method for perceived crowding lower than expected crowding, the study has proposed that it is possible to lower expected crowding by providing appropriate information on the number of tourists expected on the weekends and weekdays. Future research should control variables such as personal characteristics, seasons proper for vacation and holidays, and carefully consider their investigation and design. Moreover, it is necessary to study variables involved in expected crowding of more various space-intensive sightseeing places (mesa-events).