• Title/Summary/Keyword: Growing factor

Search Result 991, Processing Time 0.026 seconds

Antiangiogenic activity of non-aqueous fraction from Sparassis crispa extract in human umbilical vein endothelial cells (혈관내피세포에서 꽃송이버섯(Sparassis crispa) 소수성 추출물의 항혈관신생 활성)

  • Han, Jang Mi;Gong, So Youn;Sohng, Jae Kyung;Kang, Yue Jai;Jung, Hye Jin
    • Korean Journal of Food Science and Technology
    • /
    • v.51 no.2
    • /
    • pp.141-146
    • /
    • 2019
  • Sparassis crispa is an edible mushroom that is distributed in Korea, Japan, Europe, and North America. It exerts various biological activities such as immunopotentiation, anti-diabetic, anti-cancer, and anti-inflammatory effects. Recently, we separated the health functional non-aqueous fraction from the chloroform extract of S. crispa (SCF4). In this study, we evaluated the antiangiogenic activity of SCF4 in human umbilical vein endothelial cells (HUVECs). SCF4 effectively inhibited vascular endothelial growth factor (VEGF)-induced cell growth at concentrations ($5-25{\mu}g/mL$) showing no cytotoxic effects. SCF4 inhibited VEGF-induced invasiveness and tube formation ability, which are in vitro angiogenic features of HUVECs, in a dose-dependent manner. In addition, SCF4 markedly suppressed in vivo angiogenesis of chorioallantoic membrane from growing chick embryos without cytotoxicity. Furthermore, SCF4 downregulated the phosphorylation of VEGFR2, AKT, and ERK1/2, which are major angiogenic signal mediators. These results suggest that SCF4 inhibited angiogenesis by suppressing the VEGFR2 signaling pathways without cytotoxicity.

Analysis of Changes in Urban Spatial Structure for Balanced Urban Development (도시균형발전을 위한 도시공간구조 변화 진단)

  • KIM, Ho-Yong
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.24 no.2
    • /
    • pp.40-51
    • /
    • 2021
  • The purpose of this study is to diagnose urban spatial structures using spatial modeling techniques for balanced urban development as part of sustainable urban growth management. Since urban spatial structure is an interaction of various activities, it is necessary to interpret the analysis results in conjunction with the analysis of changes in spatial structural elements. In this study, population and transportation were approached for research purposes. Population data were applied to the Getis-Ord Gi* method, a spatial statistical technique, to analyze the concentration-decreasing region of the population. Traffic data analyzed the trend of centrality change by applying commuting traffic O-D data to Social Network Analysis techniques. The analysis showed that urban imbalance was growing, and the centrality of transportation was changing. The results of the analysis of spatial structure elements could be interpreted by linking the results of each factor to each neighborhood unit, predicting changes in urban spatial structure and suggesting directions for sustainable urban growth management.These results could also be used as a decision-making tool for various urban growth management policies introduced to cope with rapid urban development and uncontrollable development in many cities around the world.

Development of Revegetation Measures using Boring Technique in Rock Slopes - Focus on Lespedeza cyrtobotrya - (암반비탈면에 있어서 천공기법에 의한 녹화공법의 개발 - 참싸리를 중심으로 -)

  • Ma, Ho-Seop;Kang, Won-Seok;Park, Jin-Won
    • Journal of Korean Society of Forest Science
    • /
    • v.100 no.4
    • /
    • pp.558-564
    • /
    • 2011
  • This study was conducted to evaluate the effects of early revegetation by analyzing the characteristics of germination and growth of Lespedeza cyrtobotrya using boring technique in rock slopes. After making up a growing basis of approximately 20 cm depth and 10 cm diameter by using a boring machine, the surface of rock slopes was planted with vegetation-plant. The number of germinating populations by soil media was 23 in H.s, 22 in T.s, 12 in M.s, and 1 in M.g.s. The germination rate (%) by soil media was 19.2% in H.s, 18.3% in T.s, 10.0% in M.s and 0.8% in M.g.s. In monthly changes of growth rate, the aspect was northwest direction, the soil media was M.s, and the treatment was microorganism plot. The main factors affecting survivorship and growth of population were soil media and treatment plot. The interaction between each factor had a good effects in bearing ${\times}$ soil media, bearing ${\times}$ treatment plot, soil media ${\times}$ treatment plot. but, it is recommended that the mulching of vegetation plant is highly needed to help the germination of seed and growth of vegetation because of loss of seed and soil media occurred due to rainfall. Therefore, The result suggests that the revegetation technique using boring in rock slope was very efficient in respect of the early revegetation and the landscape.

Analyzing adolescent family meal vs. alone meal: Focusing on adolescent time use and family characteristics (청소년의 가족식사와 혼밥 비교분석: 청소년의 시간활용과 가족특성을 중심으로)

  • Cha, Seung-Eun;Lee, Hyun Ah
    • Journal of Family Relations
    • /
    • v.22 no.4
    • /
    • pp.135-156
    • /
    • 2018
  • Objectives: This study aim to determine adolescent meal time, which provides the important context of parent-child sharing time. We divided mealtime into family meal and alone meal, and analyzed the time/space context of each meal time as well as the social determinations. Method: We employed adolescents age 10-18 who live with married patents and attends school at the present (n=5,128) from the original data of Korean Time Use Survey. Results: More adolescent were engaged in family meal rather than eating alone in daily bases. However, the trend show difference by day of week and academic grade; family meal are more prevalent in weekends rather than weekdays. As adolescent reaches high school age, the proportion of eating alone beats the proportion of family meal time. Most of the meal occur at home. Having meal outside was relatively scares, especially on weekdays. Tobit and logistic analysis reveal that, on weekday meal, less school hours, more time spent at the private academy, having family leisure event, and long mother's housework hours were positively associated with family meal time. In weekend model, father's education gradient was associated with family meal time, showing higher the father's education level, there were higher chance of having weekend family meal. As for the eating alone, relevant factors were similar with family meal but the directions were the opposite; having family leisure were negatively associated with alone meal, both weekdays and weekend. Long academy hours, meal preparing and leisure alone were positively associated eating alone. Overall, weekday meal time was strongly linked with adolescent daily schedules and time use, while for weekends meal, in both family meal and alone meal, the influence of parent factors were discovered. Conclusion: The results indicates that alone meal and the family meal are not exclusively related but seem to be complementary. Families tend to enjoy family meal yet, there are some necessary situation that adolescent need to be on their own. Increase in ready-made food industries, growing independence of children by age seem partly allow adolescent children to eat alone. Careful attentions may require for monitoring weekends meal situation and the family factor of adolescent in future studies.

A Study on the Influence of Sentiment and Emotion on Review Helpfulness through Online Reviews of Restaurants (레스토랑의 온라인 리뷰를 통해 감성과 감정이 리뷰 유용성에 미치는 영향에 관한 연구)

  • Yao, Ziyan;Park, Jiyoung;Hong, Taeho
    • Knowledge Management Research
    • /
    • v.22 no.1
    • /
    • pp.243-267
    • /
    • 2021
  • Sentiment represents one's own state through the process of change to stimulus, and emotion represents a simple psychological state felt for a certain phenomenon. These two terms tend to be used interchangeably, but their meaning and usage are different. In this study, we try to find out how it affects the helpfulness of reviews by classifying sentiment and emotion through online reviews written by online consumers after purchasing and using various products and services. Recently, online reviews have become a very important factor for businesses and consumers. Helpful reviews play a key role in the decision-making process of potential customers and can be assessed through review helpfulness. The helpfulness of reviews is becoming increasingly important in practice as it is utilized in marketing strategies in business as well as in purchasing decision-making issues of consumers. And academically, the importance of research to find the factors influencing the helpfulness of reviews is growing. In this study, Yelp.com secured reviews on restaurants and conducted a study on how the sentiment and emotion of online reviews affect the helpfulness of reviews. Based on the prior research, a research model including sentiment and emotions for online reviews was built, and text mining analyzes how the sentiment and emotion of online reviews affect the helpfulness of online reviews, and the difference in the effects on emotions It was verified. The results showed that negative sentiment and emotion had a greater effect on review helpfulness, which was consistent with the negative bias theory.

Correlation Analysis between Productivity of Forage Sorghum × Sudangrass Hybrids [Sorghum bicolor (L.) Moench] and Climatic Factors in Central Northern Region of South Korea (중북부지역에서 수수×수단그라스 교잡종의 생산성과 기후요인과의 상관분석)

  • Lee, Bae Hun;Park, Hyung Soo;Jung, Jeong Sung
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.41 no.1
    • /
    • pp.41-46
    • /
    • 2021
  • Sorghum×sudangrass hybrid (Sorghum bicolor (L.) Moench, SSH) is one of the most important summer forage crop and it is widely used for silage in Korea. Agriculture is highly dependent on the climate condition and experiencing significant loss of productivity due to climate change. This study was conducted to investigate the correlation analysis between productivity of forage SSH and climatic factors in Central Northern region of South Korea for 3 years (2017 to 2019). Plant height and dry matter yield of SSH were significantly higher in Gyeonggi-do than Ganwon-do. The productivity of SSH is more closely related with temperature than other climatic factors. Maximum temperature and Growing degree days in May and June showed a positive correlation. However, correlation between production of SSH and precipitation was not clear in this study, but rainy days showed a negative correlation (0.42). In conclusion, temperature is most important climatic factor to the maintenance of plant yield.

A Comparative Study on Concentrations of Indoor and Outdoor Particulate Matters in Elementary Schools (초등학교 실내외 미세먼지 농도 비교 연구)

  • Kim, Dae-hyeon;Son, Youn-Suk;Lee, Tae-Jung;Jo, Young Min
    • Korean Journal of Remote Sensing
    • /
    • v.36 no.6_3
    • /
    • pp.1721-1732
    • /
    • 2020
  • Elementary school students spend a lot of time in a school and are more exposed to indoor air pollution. Also the students are physically growing and have a relatively high respiratory rate per unit weight compared to adults, so it is known that there is a high sensitivity to indoor air pollution. Therefore, indoor air quality in a school is becoming an important factor for the student's health. In this study, a correlation analysis using levels of indoor and outdoor Particulate Matter (PM) measured from five elementary schools in Seoul was performed to evaluate the effect of outdoor PM on indoor PM. PM ratio and indoor/outdoor (I/O) ratio were also analyzed to investigate the actual condition of indoor air quality and effect of outdoor PM on indoor PM. As a result, the correlation between indoor and outdoor PM in elementary school was more significant in PM2.5 and PM1 than PM10. In the case of I/O ratio, the I/O ratio of PM10 was higher than that of 1 in four elementary schools except SD (BB:2.21, NS: 1.67, IS: 1.73, SI: 1.17). This indicates that the activity of students has a great effect on the concentration of indoor PM10.

Big Data-based Monitoring System Design for Water Quality Analysis that Affects Human Life Quality (인간의 삶의 질에 영향을 끼치는 수질(물) 분석을 위한 빅데이터 기반 모니터링 시스템 설계)

  • Park, Sung-Hoon;Seo, Yong-Cheol;Kim, Yong-Hwan;Pang, Seung-Peom
    • Journal of Korea Entertainment Industry Association
    • /
    • v.15 no.3
    • /
    • pp.289-295
    • /
    • 2021
  • Today, the most important factor affecting the quality of human life is thought to be due to the environment. The importance of environmental monitoring systems to improve human life and improve welfare as the magnitude of the damage increases year by year due to the rapid increase in the frequency of hail, typhoons, collapse of incisions, landslides, etc. Is increasing day by day. Among environmental problems, problems caused by water quality have a very high proportion, and as there is a growing concern that the scale of damage will increase when water pollution accidents occur due to urbanization and industrialization, the demand for social water safety nets is increasing. have. In the last 5 years, 259 cases of water pollution (Han River 99, Nakdong River 31, Geum River 25, Seomjin River and Yeongsan River 19, and 85 others) have occurred in the four major river basins. Caused damage. Therefore, it is required to establish a water quality environment management strategy system based on big data that can minimize the uncertainty of the water quality environment by expanding the target of water quality management from the current water quality management system centered on the four major rivers to small and medium-sized rivers, tributaries/branches, and reservoirs. In this paper, we intend to construct and analyze a water quality monitoring system based on big data that can present useful water quality environment information by analyzing the water quality information accumulated for a long time.

High Performance Work System for Entertainment Business : An Analytic Network Process Approach (엔터테인먼트업의 고성과작업조직 : ANP 기법을 중심으로)

  • Kwon, Jung-Eon
    • Journal of Korea Entertainment Industry Association
    • /
    • v.15 no.2
    • /
    • pp.1-10
    • /
    • 2021
  • The purpose of this study is to explore a significant HPWS(High Performance Work System) model for the entertainment industry. HPWS is one of the most studied themes for managing human resources as well as a set of practices to elicit employees' commitment to an organization. Recently, the entertainment industry is growing rapidly, but it is difficult for entertainment firms to retain a stable profit unlike the manufacturing industry. This is because the performance of entertainment business tends to rely heavily on the capabilities and synergy of human resources. In order to suggest a systematic way to manage these, this research identified an effective HPWS model for entertainment business and provides a competitive advantage to entertainment firms, using ANP(Analytic Network Process). ANP is a multicriteria decision making technique that allows dependences and feedbacks among decision elements in the hierarchical or network structures in a holistic manner. The pairwise comparison data that prioritized the criteria of HPWS was collected from 28 team leaders in entertainment firms. According to our results, the most critical factor for HPWS in entertainment business is "employee involvement in decision-making." The sub-factors such as "open communication," "distributive decision-making," and "performance-driven reward" have a greater effect. These findings could provide implications for entertainment firms to determine which practices should be taken into account to accomplish HPWS.

Well-being Tourism and Wellness Mediated Effects to Improve Quality of LifeFocusing on Forest Healing Program Users (삶의 질 향상을 위한 웰빙관광과 웰니스의 매개효과: 숲치유프로그램 이용자를 중심으로)

  • Lee, Woong-Bae
    • The Journal of the Korea Contents Association
    • /
    • v.21 no.12
    • /
    • pp.264-274
    • /
    • 2021
  • This study aims to analyze the impact of well-being tourism motivation on quality of life through well-being tourism satisfaction, focusing on wellness mediated effects. Recently, despite the growing number of well-being tourism pursuing wellness, the lack of research has led to a close analysis of the impact of well-being tourism motivation on quality of life through well-being tourism satisfaction. For this study, a total of 236 people who have experienced well-being tours in the metropolitan area were surveyed from May 10 to May 21, 2021. First, well-being tourism motivation has a positive effect on well-being tourism satisfaction. Second, well-being tourism satisfaction has a positive impact on the quality of life. Third, Wellness has a positive indirect effect as a partial mediator between well-being tourism satisfaction and quality of life The implications of this study are to demonstrate the impact of well-being tourism on quality of life using Wellness' mediators This study suggests that wellness tourism plays an important role in improving the quality of life. It was analyzed that well-being tourism had a positive effect on improving the quality of life at a time when the fatigue of daily life was increased due to prolonged COVID-19. In addition, Wellis analyzed that it is an important factor in enhancing the quality of life for well-being tourists. This contributes not only to the academic contribution to the revitalization of well-being tourism, but also to the development of stress improvement routes to improve people's lives nationally.