• 제목/요약/키워드: Growing factor

검색결과 984건 처리시간 0.029초

Effect of Dietary Energy Level on Nutrient Utilization, Insulin-like Growth Factor-I and Insulin-like Growth Factor Binding Protein-3 in Plasma, Liver and Longissimus dorsi Muscle in Growing-finishing Pigs Using Soybean Oil as an Energy Source

  • Du, W.;Li, Y.J.;Zhao, G.Y.;Yin, Y.L.;Kong, X.F.
    • Asian-Australasian Journal of Animal Sciences
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    • 제22권8호
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    • pp.1180-1185
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    • 2009
  • Two experiments were carried out to study the effects of dietary energy level on nutrient digestion, nitrogen (N) utilization, growth performance, insulin-like growth factor-I (IGF-I), and insulin-like growth factor binding protein-3 (IGFBP-3) in plasma, liver and longissimus dorsi muscle in growing-finishing pigs. In experiment 1 (Exp 1), 15 castrated male pigs (Duroc${\times}$Landrace${\times}$Large White) (Body weight, BW, 55.6${\pm}$1.8 kg) were divided into three groups and fed rations containing 13.33, 14.87 and 17.35 MJ digestible energy (DE)/kg as treatments I, II and III, respectively, using soybean oil as an energy source. The experiment lasted 8 days and faecal and urinary samples were collected during the last 3 days. The results showed that the digestibility of dry matter (DM), energy and N was increased from treatments I to III (p<0.01). N-retention and N-retention rate were not influenced by dietary DE level (p>0.05). In experiment 2 (Exp 2), 36 female pigs (Duroc${\times}$Landrace${\times}$Large White) (BW 41.5${\pm}$3.8 kg) were divided into three groups. The pigs were fed with the same three rations used in Exp 1 for 60 days. At the end of Exp 2, eight pigs were selected from each group for blood sampling and 4 pigs for slaughter trial. The results indicated that average daily feed intake (ADFI) and N-intake were significantly decreased (p<0.01), and DE intake (p<0.01) and average daily gain (ADG) (p<0.05) were increased. IGF-I and IGFBP-3 in plasma were increased (p<0.05). No significant differences in IGF-I and IGFBP-3 in liver and longissimus dorsi muscle were found between different treatments. It was concluded that higher dietary DE level improved nutrient digestibility, ADG and feed/gain ratio when soybean oil was used as an energy source in the ration of growing-finishing pigs. No significant differences were found in Nretention and IGF-I and IGFBP-3 in liver and longissimus dorsi muscle between different treatments.

사춘기 소녀용 브래지어 개발을 위한 흉부 형태 분석에 관한 연구 (A Study on Breast Shape Analysis for Developing Brassiere of the Girls at Adolescence)

  • 이경화;임정란
    • 복식
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    • 제40권
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    • pp.81-93
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    • 1998
  • It is necessary to research shape of the breast of girls at adolescence for developing well-fit brassiers. 313 participants reside in Chonju and Kunsan were gathered for body measurement. The conclusion of this study can be summarized as follows. 1) The Analysis of Body Shape by Measurement. Comparing Age GroupⅠ(aged 10 to 12)' measurement with Age GroupⅡ(aged 13 to 15)', Each items has statistical significance. Two groups differed in the length, girth, depth, width items. 2) Factor Analysis of Body Measurement (1) Age GroupⅠ'characteristics were categorized Three Factor : Breast size and breast apex length. Breast volume, Length of the Breast part. (2) Age GroupⅡ' characteristics consist of four factors, which are named as breast size and its jut (first factor), breast volume (second factor), contour of breast profile & its jut (third factor), shoulder length (fourth factor). 3) Characteristics of Breast Shape. (1) Breast shapes of Age GroupⅠ are classified into three types. Types 1 is a protruded and more voluminous shape. Type 2 is the most voluminous and breast fatness is highest. Type 3 is the smallest and flat shape growing now. (2) Breast shapes of Age GroupⅡ are also classified into three types. Type 1 is the longest in length and middle in fatness, voluminous in size. Type 2 is the smallest in stature and the slimmest in fatness in breast shape. Type 3 is middle in length, the fattest and the most voluminous in breast.

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Electrochemical and Biochemical Analysis of Ethanol Fermentation of Zymomonas mobilis KCCM11336

  • Jeon, Bo-Young;Hwang, Tae-Sik;Park, Doo-Hyun
    • Journal of Microbiology and Biotechnology
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    • 제19권7호
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    • pp.666-674
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    • 2009
  • An electrochemical bioreactor (ECB) composed of a cathode compartment and an air anode was used in this study to characterize the ethanol fermentation of Zymomonas mobilis. The cathode and air anode were constructed of modified graphite felt with neutral red (NR) and a modified porous carbon plate with cellulose acetate and porous ceramic membrane, respectively. The air anode operates as a catalyst to generate protons and electrons from water. The growth and ethanol production of Z. mobilis were 50% higher in the ECB than were observed under anoxic nitrogen conditions. Ethanol production by growing cells and the crude enzyme of Z. mobilis were significantly lower under aerobic conditions than under other conditions. The growing cells and crude enzyme of Z. mobilis did not catalyze ethanol production from pyruvate and acetaldehyde. The membrane fraction of crude enzyme catalyzed ethanol production from glucose, but the soluble fraction did not. NADH was oxidized to $NAD^+$in association with $H_2O_2$reduction, via the catalysis of crude enzyme. Our results suggested that NADH/$NAD^+$balance may be a critical factor for ethanol production from glucose in the metabolism of Z. mobilis, and that the metabolic activity of both growing cells and crude enzyme for ethanol fermentation may be induced in the presence of glucose.

성장기 암컷 쥐에서 Arginine 첨가 식이가 골 대사 지표 및 호르몬에 미치는 영향 (Effects of Arginine Supplementation on Bone Markers and Hormones in Growing Female Rats)

  • 최미자
    • Journal of Nutrition and Health
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    • 제40권4호
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    • pp.320-326
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    • 2007
  • An important related question is whether arginine has influence bone metabolism. The effect of arginine supplements on bone markers and related hormones were studied in young female Sprague-Dawley rats fed either an arginine supplemented diet or control diet. Twenty four rats (body weight 83${\pm}$5 g) were randomly assigned to one of two groups, consuming casein or casein with supplemented arginine diet. All rats were fed on experimental diet and deionized water ad libitum for 9 weeks. Bone formation was measured by serum osteocalcin and alkaline phosphatase (ALP) concentrations. And bone resorption rate was measured by deoxypyridinoline (DPD) crosslinks immunoassay and corrected for creatinine. Serum osteocalcin, growth hormone, estrogen, insulin-like growth factor-1 (IGF-1), parathyroid hormone (PTH) and calcitonin were analyzed using radioimmunoassay kits. The weight gain and mean food intake were not affected regardless of diets. The rats fed arginine-supplemented diet had not significantly different in ALP, osteocalcin, crosslinks value, PTH, estradiol, and IGF-1 compared to those fed casein diet group. The arginine-supplemented group had significantly higher growth hormone and calcitonin than casein group. This study suggests that arginine is beneficial for bone formation in growing female rats. Therefore exposure to diet which rich in arginine early in life may have benefits for bone formation and osteoporosis prevention.

SENSITIVITY ANALYSIS OF SUV PARAMETERS ON ROLLOVER PROPENSITY

  • Jang, B.C.;Marimuthu, R.P.
    • International Journal of Automotive Technology
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    • 제7권6호
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    • pp.703-714
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    • 2006
  • The growing concern surrounding rollover incidences and consequences of Sports Utility Vehicles(SUV) have prompted to investigate the sensitivity of critical vehicle parameters on rollover. In this paper, dynamic rollover simulation of Sports Utility Vehicles is carried out using a validated nonlinear vehicle model in Matlab/Simulink. A standard model is considered and critical vehicle parameters like CG height, track width and wheel base are varied within chosen specified limits to study its influence on roll behavior during a Fishhook steering maneuver. A roll stability criterion based on Two Wheel Lift Off(TWLO) phenomenon is adopted for rollover propensity prediction. Further dynamic rollover characteristics of the vehicle are correlated with Static Stability Factor(SSF), Roll Stability Factor(RSF) and Two Wheel Lift Off Velocity(TWLV). These findings will be of immense help to SUV chassis designers to determine safety limits of critical vehicle parameters and minimize rollover incidences.

Prediction of Cognitive Ability Utilizing a Machine Learning approach based on Digital Therapeutics Log Data

  • Yeojin Kim;Jiseon Yang;Dohyoung Rim;Uran Oh
    • International journal of advanced smart convergence
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    • 제12권2호
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    • pp.17-24
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    • 2023
  • Given the surge in the elderly population, and increasing in dementia cases, there is a growing interest in digital therapies that facilitate steady remote treatment. However, in the cognitive assessment of digital therapies through clinical trials, the absence of log data as an essential evaluation factor is a significant issue. To address this, we propose a solution of utilizing weighted derived variables based on high-importance variables' accuracy in log data utilization as an indirect cognitive assessment factor for digital therapies. We have validated the effectiveness of this approach using machine learning techniques such as XGBoost, LGBM, and CatBoost. Thus, we suggest the use of log data as a rapid and indirect cognitive evaluation factor for digital therapy users.

Positive effects of grazing on blood components and intestinal microbiota in growing horses

  • Ji Hyun Yoo;Jong An Lee;Jae Young Choi;Sang Min Shin;Moon Cheol Shin;Hyeon Ah Kim;Yong Jun Kang;Hee Chung Ji;In Cheol Cho;Byoung Chul Yang
    • 농업과학연구
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    • 제49권4호
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    • pp.963-971
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    • 2022
  • Production of high-quality horses is important to make the horse industry grow. Grazing during the growing period can be an important factor affecting the production of high-quality horses. The objective of this study was to determine the effects of grazing on growing horses by analyzing their blood components and intestinal microbiota. Twelve growing horses for evaluating blood components and ten growing horses for evaluating intestinal microbiota were raised for about seven months and separated by two treatments: grazing vs. stable. Complete blood count, blood chemistry, and creatine kinase levels were analyzed as blood components and a 16s rRNA gene sequence analysis was performed to analyze intestinal microbiota. Calcium ions tended to be lower in the group with grazing treatment. Alkaline phosphatase and creatine kinase tended to be higher in the group with grazing treatment. These results indicate that grazing can provide horses with more exercise than staying in stables. At the phylum level, Firmicutes/Bacteroidetes ratios in grazing and stable groups were 4.2 and 6.5, respectively. Because various studies have reported that a. high Firmicutes/Bacteroidetes ratio indicates obesity, the method of raising horses might affect their physical ability. At the species level, rates of Clostridium butyricum in grazing and stable groups were 3.2% and 13.1%, respectively. Some strains of C. butyricum can cause several diseases such as botulism. These results indicate that grazing can positively affect growing horses in terms of blood components and intestinal microbiota. Moreover, grazing can be helpful to make growing horses healthy through proper exercise.

생쥐 난소의 발생단계에 따른 Growth Differentiation Factor-9의 유전자 발현 (Expression of Growth Differentiation Factor-9 in the Mouse Ovaries at Different Developmental Stages)

  • 윤세진;이경아;고정재;차광열
    • 한국발생생물학회지:발생과생식
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    • 제3권1호
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    • pp.95-100
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    • 1999
  • Growth/differentiation factor-9 (GDF-9)은 transforming growth factor $\beta$ (TGF-$\beta$) superfamily의 member로서 난소의 난자에서만 특이적으로 발현되며 정상적인 난포발달에 있어 필수적인 성숙인자로 최근에 알려졌다. 본 연구는 RT-PCR을 통해 생쥐의 원시난포에서의 GDF-9 mRNA의 발현 여부와 함께 난포의 발달단계에 따른 상대적인 발현량을 분석하고자 실시하였다. 본 실험에는 ICR 생쥐를 사용하여 질전 (vaginal plug)이 확인된 날을 1일로 하여 임신 19일의 태아와 태어난 날을 1일로 하여 생후 1일, 10일, 21일, 28일된 생쥐 난소를 실험에 사용하였다. 각 발달단계의 난소조직으로부터 total RNA를 추출하여 GDF-9 유전자 발현 여부를 확인하였으며 이들을 $\beta$-actin에 대해 상대적인 정량분석을 하였다. GDF-9 유전자 발현은 아직은 성장을 시작하지 않은 임신 19일의 태아의 난소, 대부분이 원시난포로 이루어진 태어난 날의 생쥐 난소에서도 확인되었으며, 성장이 왕성하게 진행되고 있는 난포 즉, antrum 형성 이전의 growing follicles이 주를 이루는 생후 10일째의 난소에서 가장 높은 GDF-9 유전자 발현이 관찰되었다. 나머지 단계의 난소에서는 거의 비슷한 정도로 발현함을 관찰할 수 있었다. 본 연구의 결과는 생쥐의 원시난포에도 GDF-9 transcript가 존재한다는 것을 확실하게 증명하였으며, GDF-9이 생쥐의 초기 난포발달에 중요한 역할을 할 것이라는 가능성을 시사한다.

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민간경호경비의 발전에 대한 자본주의의 사회환경적 해석 (Social Environment Research of Capitalism for the Private Security Development)

  • 김창호;공배완
    • 시큐리티연구
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    • 제7호
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    • pp.125-154
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    • 2004
  • Capitalism is based on a material desire of the human being. the social control of capital value and the management of capital ability reflects the actual condition of the capitalism well. The unconstrained growing and the expansion of capitalism, it finally lost social meaning and an importance of human being element and the safety of the civilian life, began to threat the security of citizen by forming over the material center structure of society. Improving human life quality and material richness on their life leads positive factor of capitalism whereas is causing several crimes through the society which is being threatened around a human being life for a negative factor of the capitalism. Therefore capitalistic social system has offered both a positive factor 'growing' and 'richness' and that of a negative 'structural poverty' and 'lack of security' and they have been remaining the assignment of capitalism 'poverty' and 'security' by settlement in the society for a extremely phenomenon of both sides. The objective of this research is to build its study theory and establish its causal relation by illuminating for the social environment of capitalism for a private guard or a development background of the civil security contributing for citizen security, as well as gets the clue of the development possibility of the civil guard and escort field and the development of capitalism. In Korea because their recognition of the study approach and the social safety for social security control function is still staying first step and our daily life is annoying from various threat of the society, many studies and the realistic necessity of experience related with social security is being studied. In addition, The development possibility of the civil guard and defense at the civil field which will be keep the social security has a wide position but its study approach and realistic comprehension is still in insufficient condition. Consequently, this research is started to grasp the security of civil fiend and to grope a development possibility through the research of capitalism.

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침구요법(鍼灸療法)에 의한 발모관련 인자들의 발현에 대한 실험적 연구 (Experimental Studies on the Expression of Hair Growth Related Factors after Acupuncture & Moxibustion Therapy)

  • 김호일;김정무;이창현
    • 동의생리병리학회지
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    • 제25권4호
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    • pp.674-682
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    • 2011
  • The present study was undertaken to investigate the effect of acupuncture & moxibustion therapy on the hair follicle growth of skin 5 days and 10 days by macroscopic, microscopic and immunohistochemical methods. The results were as follows : Macroscopic hair follicle growth of plum-blossom needle treated group and strong moxibustion treated group was more increase than that of control group. Microscopic hair follicle growth of plum-blossom needle treated group and strong moxibustion treated group was hair growing cycle, anagen phase VI and that of control group and weak moxibustion treated group was hair growing cycle, anagen phase IV. Immunohistochemical observations on the expression of various growth factors, enzyme and receptor in hair follicle cycle after local treatment of acupuncture & moxibustion therapy are as follows: Expression of fibroblast growth factor was more intense in epidermis in plum-blossom needle treated group, epidermis and secondary hair germ cells in strong moxibustion treated group than control group. Expression of epidermal growth factor was more intense in epidermis in all experimental groups, and secondary hair germ cells in moxibustion treated group than control group. Expression of c-kit receptor was more intense in epidermis, secondary hair germ cells, outer root sheath in all experimental groups than control group. Expression of protein kinase C-${\alpha}$ was more intense in epidermis, secondary hair germ cells, outer root sheath in all experimental groups than control group. Expression of vascular endothelial growth factor was more intense in epidermis, bulge, secondary hair germ cells, outer root sheath in plum-blossom needle treated group and strong moxibustion treated group than control group. We concluded that acupuncture & moxibustion therapy related to the expression of various growth factors, enzymes and receptor on the hair growth cycle for hair growth.