• Bulletin of the Korean Chemical Society
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• 제17권12호
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• pp.1117-1123
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• 1996

Chiral recognition models for resolving π-basic N-acyl-α-(1-naphthyl)alkylamines and π-acidic N-(3,5-dinitrobenzoyl)-α-amino alkyl esters on a (S)-tyrosine-derived chiral stationary phase (CSP) containing both π-basic and π-acidic interaction site have been proposed. In the models, the CSP was supposed to interact with the analytes through the π-π interaction between the 3,5-dinitrophenyl or the 3,5-dimethylphenyl group of the CSP and the 1-naphthyl or the 3,5-dinitrophenyl group of the analyte, and through the hydrogen bonding interaction between the appropriate N-H hydrogen of the CSP and the appropriate carbonyl oxygen of the analyte. In this instance, the alkyl substituent of the pertinent enantiomer of the analyte was found to intercalate between the adjacent strands of the bonded phase and consequently control the trends of the separation factors.

• 도시과학
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• 제6권2호
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• pp.59-72
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• 2017

Studies on the calculation of accident costs include the approach on calculating damage costs covering all accidents regardless of first or secondary party and the one calculating damage costs generated by a single victim. These two approaches have a limitation of considering a subject for costs analysis as a single entity. In addition, research on estimating the interaction effects caused in the relationship between diverse traffic accident features and factors remains inadequate since most studies focused on calculating costs incurred in a single entity such as a victim, damaged building, or social organization in charge of managing car accident. This study intends to identify the expected range of old age where a specific interaction effect would remain, compare accidents between old age section and the entire age section, and discover an exogenous variable to be applied in accident drop effects in senior people and reduced benefits by calculating and testing additional accident costs in case the first party and the second party all pertain to the senior age section. By classifying the entire accidents caused by old drivers according to the types of cars, significant coefficients representing the influence that affects car accidents according to the characteristics are calculated and set them as the representative variables by selecting top variable in accordance with from low to high order. Furthermore, characteristics on five age groups such as a group of over 65 and less than 70, a group of over 70 and less than 75, a group of over 75 and less than 80, a group of over 80 and less than 85, and a group of over 85 are elicited and compared them with these preselected accident characteristics variables, thereby identifying what changing effects come out.

• The Journal of Advanced Prosthodontics
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• 제10권3호
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• pp.236-244
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• 2018

PURPOSE. To determine the discrepancy in monolithic zirconium dioxide crowns made with computer-aided design and computer-aided manufacturing (CAD/CAM) systems by comparing scans of silicone impressions and of master casts. MATERIALS AND METHODS. From a Cr-Co master die of a first upper left molar, 30 silicone impressions were taken. The 30 silicone impressions were scanned with the laboratory scanner, thus obtaining 30 milled monolithic yttrium stabilized zirconium dioxide (YSZD) crowns (the silicone group). They were poured and the working models were scanned, obtaining 30 milled monolithic yttrium stabilized zirconium dioxide (YSZD) crowns (the plaster group). Three predetermined points were analyzed in each side of the crown (Mesial, Distal, Vestibular and Palatal), and the marginal fit was evaluated with SEM (${\times}600$). The response variable is the discrepancy from the master model. A repeated measures ANOVA with two within subject factors was performed to study significance of main factors and interaction. RESULTS. Mean marginal discrepancy was $22.42{\pm}35.65{\mu}m$ in the silicone group and $8.94{\pm}14.69{\mu}m$ in the plaster group. The statistical analysis showed significant differences between the two groups and also among the four aspects. Interaction was also significant (P=.02). CONCLUSION. The mean marginal fit values of the two groups were within the clinically acceptable values. Significant differences were found between the groups according to the aspects studied. Various factors influenced the accuracy of digitizing, such as the design, the geometry, and the preparation guidance, as well as the texture, roughness and the color of the scanned material.

• Geomechanics and Engineering
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• 제38권5호
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• pp.517-528
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• 2024

For numerous tunnelling projects implemented in urban areas due to limited space, it is crucial to take into account the interaction between the foundation, ground, and tunnel. In predicting the deformation of piled foundations and the ground during twin tunnel excavation, it is essential to consider various factors. Therefore, this study derived a prediction model for pile group settlement using machine learning to analyze the importance of various factors that determine the settlement of piled foundations during twin tunnelling. Laboratory model tests and numerical analysis were utilized as input data for machine learning. The influence of each independent variable on the prediction model was analyzed. Machine learning techniques such as data preprocessing, feature engineering, and hyperparameter tuning were used to improve the performance of the prediction model. Machine learning models, employing Random Forest (RF), eXtreme Gradient Boosting (XGB), and Light Gradient Boosting Machine (LightGBM, LGB) algorithms, demonstrate enhanced performance after hyperparameter tuning, particularly with LGB achieving an R² of 0.9782 and RMSE value of 0.0314. The feature importance in the prediction models was analyzed and P_N was the highest at 65.04% for RF, 64.81% for XGB, and P_CTC (distance between the center of piles) was the highest at 31.32% for LGB. SHAP was utilized for analyzing the impact of each variable. P_N (the number of piles) consistently exerted the most influence on the prediction of pile group settlement across all models. The results from both laboratory model tests and numerical analysis revealed a reduction in ground displacement with varying pillar spacing in twin tunnels. However, upon further investigation through machine learning with additional variables, it was found that the number of piles has the most significant impact on ground displacement. Nevertheless, as this study is based on laboratory model testing, further research considering real field conditions is necessary. This study contributes to a better understanding of the complex interactions inherent in twin tunnelling projects and provides a reliable tool for predicting pile group settlement in such scenarios.

• 융합정보논문지
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• 제10권6호
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• pp.109-118
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• 2020

본 연구는 유아의 로봇 상호작용 경험 유무, 성별 및 연령이 엔터테인먼트 로봇 견과의 친밀함에 영향을 미치는지 분배원리를 활용하여 살펴보는 데 목적이 있다. 이를 위해 서울지역 어린이집 유아 총 70명을 대상으로 두 가지 종류의 실험을 하였다. 실험 1은 상호작용 여부 영향을 살펴본 것으로 만 5세 유아 총 34명(실험집단 17명, 비교집단 17명), 실험2는 성별, 연령 영향에 관한 연구로 만 3세에서 만 5세까지 유아 각 12명씩 총 36명(사전, 사후 집단)이다. 연구 결과, 첫째, 로봇과 상호작용을 경험한 실험집단이 엔터테인먼트 로봇 견에게 유의한 친밀함을 느꼈고 그 이유는 정서로 밝혀졌다(실험1). 둘째, 엔터테인먼트 로봇 견과의 친밀함에 유아의 성별은 큰 영향을 미치지 못하며 연령은 reverted U 추이를 나타냈다(실험2).

• 대한화학회지
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• 제36권6호
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• pp.802-811
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• 1992

카르벤-올레핀-전이금속착물들[$(CO)_4M=CHX(CH_2=CH_2)$] (X: $OCH_3,\;NHCH_3,\;SCH_3$, M: C, Mo, W)의 형태에 대하여 확장된 Huckel 방법으로 계산하여 연구하였다. $d^6$ 전이금속 8면체 착물에서는 두 개의 인자 즉 금속에서 리간드로의 역제공과 리간드-리간드 상호작용이 안정한 형태를 결정해 준다는 사실이 밝혀졌지만 카르벤에 $\pi$-전자를 수용하는 리간드와 $\pi$-전자를 주는 기가 배위되어 있을 때 리간드-리간드 상호작용이 우세하므로 착물이 형태를 결정해 주는 주요한 인자라고 예측된다.

• Journal of Preventive Medicine and Public Health
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• 제42권6호
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• pp.360-370
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• 2009

Genetic factors clearly play a role in carcinogenesis, but migrant studies provide unequivocal evidence that environmental factors are critical in defining cancer risk. Therefore, one may expect that the lower availability of substrate for biochemical reactions leads to more genetic changes in enzyme function; for example, most studies have indicated the variant MTHFR genotype 677TT is related to biomarkers, such as homocysteine concentrations or global DNA methylation particularly in a low folate diet. The modification of a phenotype related to a genotype, particularly by dietary habits, could support the notion that some of inconsistencies in findings from molecular epidemiologic studies could be due to differences in the populations studied and unaccounted underlying characteristics mediating the relationship between genetic polymorphisms and the actual phenotypes. Given the evidence that diet can modify cancer risk, gene-diet interactions in cancer etiology would be anticipated. However, much of the evidence in this area comes from observational epidemiology, which limits the causal inference. Thus, the investigation of these interactions is essential to gain a full understanding of the impact of genetic variation on health outcomes. This report reviews current approaches to gene-diet interactions in epidemiological studies. Characteristics of gene and dietary factors are divided into four categories: one carbon metabolism-related gene polymorphisms and dietary factors including folate, vitamin B group and methionines; oxidative stress-related gene polymorphisms and antioxidant nutrients including vegetable and fruit intake; carcinogen-metabolizing gene polymorphisms and meat intake including heterocyclic amins and polycyclic aromatic hydrocarbon; and other gene-diet interactive effect on cancer.

• 한국보건간호학회지
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• 제19권2호
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• pp.261-273
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• 2005

Purpose: The purpose of this study was to explore the self management and related factors that affect the self management of diabetes between the middle aged and elderly groups. Method: This study was based by the conceptual framework of Cox's interaction model of client health behavior. The subjects were two groups; the middle aged group, 80 and the elderly group, 85 who were diabetes mellitus patients. Result: In the middle aged group, gender, education and social support were significantly correlated with self-management of diabetes mellitus. In the elderly group, gender, education, social support and the duration of diagnosis were significantly correlated with self-management of diabetes mellitus. In too middle aged group, the intrinsic motivation of diabetes mellitus patients and their understanding of diabetes were significantly correlated with self-management of diabetes mellitus. Understanding of diabetes and self perception were significantly correlated with self-management in middle aged group. In the elderly group, intrinsic motivation, understanding of diabetes and the attitude of the patients were significantly correlated with self-management Conclusion: In the middle aged group, maintaining a positive attitude of diabetes, reducing stress and continuous social support were important for improving self-management of diabetes mellitus. In the elderly group, enhancing their knowledge of diabetes, and maintaining continuous social support were important to improve self-management of diabetes mellitus.

• 대한물리치료과학회지
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• 제26권2호
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• pp.51-60
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• 2019

Background: The purpose of this study was to investigate the effects of HBOT (hyperbaric oxygen therapy) on the pain, ROM (range of motion) and muscle fatigue recovery of DOMS (delayed onset muscle soreness). Design: Randomized Controlled Trial. Methods: Twenty-six subjects who are student in their 20s at a university participated in this study, these subjects were assigned into two groups, a control group (n=12) and an experiment group (n=14). The subjects in experimental group were intervened by HBOT (40 minutes, 1.3 ATA), while ones on control group weren't by any intervention after induced DOMS. Results: First, in the comparison of VAS (visual analog scale), there were significant variations with the period (p<0.001), interaction of period (p<0.05) and group (p<0.05). In the comparison of PPT (pressure pain threshold), there were significant variations with the period (p<0.001) and interaction of period (p<0.05). Second, in the comparison of ROM, there were significant variations with the period (p<0.001), interaction of period (p<0.001) and group (p<0.01). Third, in the comparison of CK (creatine kinase) and LDH (lactate dehydrogenase), there no signigicant variations with all measure variables. Conclusion: The above results indicated that HBOT were effective to decrease the pain and improve the ROM in DOMS. Also the statistical significant variations of blood factors of muscle fatigue were not found in this.

• International Journal of Safety
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• 제10권1호
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• pp.32-35
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• 2011

Lifting capacity and difficulty of task are influenced by body posture. In RULA and REBA, the body was divided into segments which formed two groups, A and B. Group A includes the upper and lower arm and wrist while group B includes the neck, trunk and legs. This ensures that whole body posture is recorded so that any awkward or constrained posture of the legs, trunk or neck which might influence the posture of the upper limb. This study aimed to measure MVC (maximum voluntary contraction) and subjective judgment in psychophysical method (Borg's scale) according to trunk and upper arm angle and to analyze results statistically. The results of this study were that lifting capacity was more influenced by interaction of body posture rather than angles of each part, and MVC variation according to trunk and upper arms angles should different patterns. This means that we consider the interaction of trunk angles and upper arm angles when we access risk factors of the postures. This survey would be also the basic data to evaluate difficulty of lifting tasks according to body postures ergonomically.