• 대한물리의학회지
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• 제18권1호
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• pp.87-97
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• 2023

PURPOSE: The purpose of this study was to investigate the effect of multimodal intervention through VR (virtual reality)-based immersion program on the cognitive function and brain activity of patients with mild cognitive impairment. METHODS: The subjects of the study were 10 people in the experimental group who applied a complex intervention that performed cognitive tasks using the movement of the upper extremities through the VR program, and 10 people in the control group who received traditional occupational therapy. After the study intervention was applied 5 times a week, 30 minutes a day for a total of 8 weeks, LOTCA-G(Lowenstein Occupational Therapy Cognitive Assessment for Geriatric Population) and NIRSIT LITE were used to compare. RESULTS: Significant differences in cognitive function and brain activity were noted between the pre- test and post-test in the experimental group. Brain activity showed statistically significant differences in four channels of the working memory domain and one channel of the metacognitive domain (p < . 05). Comparative analysis of the difference between the two groups revealed statistically significant differences in cognitive function and brain activity. The brain activity showed statistically significant differences in three channels of the working memory domain and one channel of the metacognitive domain (p < .05). CONCLUSION: Through the results of this study, it was found that the complex intervention of performing cognitive tasks using upper extremity movements through the VR program had a positive effect on the cognitive function of patients with mild cognitive.

• 한국콘텐츠학회논문지
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• 제12권1호
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• pp.416-429
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• 2012

본 연구는 회복지향의 통합재활프로그램이 만성정신분열병 환자의 증상, 인지 사회적 기능, 재활동기, 정신건강회복수준에 미치는 효과를 검증하고자 시도되었다. 이 프로그램은 인지분화, 정서관리, 직업재활, 가족교육으로 구성된 4개의 소프로그램과 함께 동기강화프로그램이 포함되어 있다. 연구대상은 지방소재의 일개 국립병원에 입원한 정신신분열증 환자로, 실험군 18명과 대조군 16명으로 구성된 비동등성 대조군 전후시차 설계를 사용하였다. 수집된 자료는 SPSS 12.0을 이용하여 통계 분석하였다. 프로그램의 효과를 검증한 결과, 인지 사회적 기능에 별다른 효과를 나타내지 못했으나, 재활동기수준(유지단계에서 p=.027)과 정신건강회복수준(p=.039)에서만 실험군과 대조군에서 유의한 차이를 나타내어 제한적인 효과를 나타내었다. 입원세팅에서 단기간의 회복지향의 통합재활프로그램은 증상감소나 기능향상보다는 재활 동기나 정신건강회복수준을 향상시키는데 보다 효과적으로 활용될 수 있는 가능성이 있는 것으로 보인다. 임상세팅에서 보다 회복지향적인 서비스를 제공하기 위한 노력이 필요하다.

• The Journal of Korean Physical Therapy
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• 제12권2호
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• pp.83-93
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• 2000

29 dementia patients over 60 years of no in the nursing home were assigned to execute rehabilitation program a month for 3 months. 1 evaluated MBI scores and MMSE scores and analyzed correlation between both scores. Analyses of results were as follows : 1. In the experimental group with rehabilitation program. ADL and cognitive function were improved significantly(p<0.05). 2. In the control group with no rehabilitation program. ADL was decreased significantly(p<0.05), cognition was not changed (pgt;0.05). 3. There were significant rises in MBI scores and MMSE scores in the experimental group(p<0.05). 4. There was a significant fall in MBI scores in the control group(p<0.05). a no change in MMSE scores in the control group(p>0.05). 5. There was strong correlation between ADL and cognition in the experimental group and the control group. 6. Inverse correlation revealed between the experimental group and the control group in ADL. 7. Inverse correlation revealed between the experimental group and the control group in cognition.

• Journal of Korean Neurosurgical Society
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• 제54권6호
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• pp.484-488
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• 2013

Objective : To examine the synergistic effects of both computer-assisted cognitive rehabilitation (CACR) and transcranial direct current stimulation (tDCS) on cognitive function in patients with stroke. Methods : The current double-blind, sham-controlled study enrolled a total of 11 patients who were newly diagnosed with stroke. The patients of the tDCS group (n=6) completed sessions of the Korean computer-assisted cognitive rehabilitation program five times a week for 30 minutes a session during a mean period of 18.5 days concomitantly with the anodal tDCS over the bilateral prefrontal cortex combined with the CACR. The patients of the control group (n=5) also completed sessions of the sham stimulation during a mean period of 17.8 days. Anodal tDCS over bilateral prefrontal cortex (F3 and F4 in 10-20 EEG system) was delivered for 30 minutes at an intensity of 2 mA. Cathode electrodes were applied to the non-dominant arm. All the patients were evaluated using the Seoul Computerized Neuropsychological Test (SCNT) and the Korean Mini-Mental State Examination. Results : Mann-Whitney U test revealed a significant difference between the two groups. The patients of the tDCS group achieved a significant improvement in the post/pre ratio of auditory continuous performance test and visual continuous performance test on the SCNT items. Conclusion : Our results indicate that the concomitant use of the tDCS with CACR to the prefrontal cortex may provide additional beneficial effects in improving the cognitive dysfunction for patients with stroke.

• 대한간호학회지
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• 제47권1호
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• pp.1-13
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• 2017

Purpose: The purpose of this study was to examine the effects of a cognitive training program on neurocognitive task performance and activities of daily living (ADL) in patients who had a stroke. Methods: The research design for this study was a nonequivalent control group non-synchronized design. Patients were assigned to the experimental (n=21) or control group (n=21). The experimental group received a 4-week cognitive training program and usual care (i.e., rehabilitation service), while the control was received usual care only. Cognitive function was measured with a standardized neurocognitive test battery and ADL was assessed at baseline and one and two months after completion of the intervention. Repeated measures ANOVA was used to determine changes in cognitive function and ADL over 2 months. Results: The interaction of group and time was significant indicating that the experimental group showed improvement in attention, visuospatial function, verbal memory, and executive function compared to the control group which had a sustained or gradual decrease in test performance. A significant group by time interaction in instrumental ADL was also found between the experimental group with gradual improvement and the control group showing no noticeable change. Conclusion: Findings show that the cognitive training program developed in this study is beneficial in restoring cognitive function and improving ADL in patients following a stroke. Further study is needed to investigate the long-term relationship between cognitive training participation and cognitive improvement and effective functioning in daily living.

• 재활치료과학
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• 제6권2호
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• pp.71-83
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• 2017

Objective: This study was to develop and verify the effects of the exercise-cognitive combined dual-task training program on cognitive function and depression of the elderly with mild cognitive impairment(MCI). Methods: The subjects were randomly assigned to the exercise-cognitive combined dual-task training group(n=32) or single-task training group(n=31). To identify the effects on cognitive function, general cognitive function, frontal lobe function, and attention/working memory were measured. Depression was evaluated using Korean version of Geriatric Depression Scale. The outcome measurements were performed before and after the 8 weeks of intervention(2 days per week). Results: After 8 weeks, general cognitive function, frontal cognitive function, attention/working memory function, depression of the dual-task training group were significantly increased than those of the single-task training group(p<0.05). Conclusion: The results indicated that an exercise-cognitive combined dual-task training for MCI was effective in improving general cognitive function, frontal /executive function, attention/working memory function and reducing depression.

• The Journal of Korean Physical Therapy
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• 제28권6호
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• pp.355-363
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• 2016

Purpose: In this study, we investigated the effectiveness of a 12-week virtual reality exercise program using the Nintendo Wii console (Wii) in improving balance, emotion, and quality of life among patients with cognitive decline. Methods: The study included 30 patients with cognitive decline (12 female, 18 male) who were randomly assigned to an experimental (n=15) and control groups (n=15). All subjects performed a traditional cognitive rehabilitation program and the experimental group performed additional three 40-minute virtual reality based video game (Wii) sessions per week for 12 weeks. The berg balance scale (BBS) was used to assess balance abilities. The short form geriatric depression scale-Korean (GDS-K) and the Korean version of quality of life-Alzheimer's disease (KQOL-AD) scale were both used to assess life quality in patients. Statistical significance was tested within and between groups before and after treatment, using Wilcoxon signed rank and Mann-Whitney u-tests. Results: After 36 training sessions, there were significant beneficial effects of the virtual reality game exercise on balance (BBS), GDS-K, and KQOL-AD in the experimental group when compared to the control group. No significant difference was observed within the control group. Conclusion: These findings demonstrate that a virtual reality-training program could improve the outcomes in terms of balance, depression, and quality of life in patients with cognitive decline. Long-term follow-ups and further studies of more efficient virtual reality training programs are needed.

• 한국산학기술학회논문지
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• 제21권8호
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• pp.537-545
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• 2020

본 연구는 회복기 단계에 있는 뇌혈관 질환자를 대상으로 가상현실 콘텐츠를 활용한 인지재활프로그램의 임상적 적용 효과를 알아보았다. 연구방법은 회복기 단계의 뇌혈관 질환자 34명을 대상으로 대조군(16명)과 실험군(18명)으로 나눈 후에 가상현실 콘텐츠 기반의 인지재활프로그램을 적용한 후, 인지기능과 일상생활활동 능력, 상지기능에서의 효과를 비교하고자 하였다. 대조군에는 보편적인 재활치료 프로그램을 실시하고, 실험군에서는 보편적인 재활치료 프로그램과 가상현실 콘텐츠 기반의 인지재활프로그램을 제공하였다. 두 집단 모두 하루 2회(1회 30분씩)씩, 주 5회, 4주간(총 20회기) 실시하였다. 중재 결과, 두 집단 모두 일상생활활동 능력이 모두 유의미하게 향상되었지만(p<.05), 실험군에서의 변화량이 대조군보다 5점정도 더 향상되었다(p<.05). 인지기능에서도 실험군과 대조군이 유의미한 차이를 보였고(p<.05), 변화량에서 실험군이 대조군보다 2점정도의 변화 수치를 보였다(p<.05). 상지기능에서는 대조군과 실험군 간의 유의마한 차이는 없었고(p>.05), 전후 변화량을 비교한 결과 실험군이 대조군보다 0.7점정도 유의미한 변화폭을 보였다(p<.05). 가상현실 콘텐츠를 활용한 인지재활프로그램이 일반적인 재활치료 프로그램에 비해서 일상생활활동 능력과 인지기능에서의 유의미한 향상 폭의 차이가 있다는 것을 확인하는 연구였다.

• 한국산학기술학회논문지
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• 제16권9호
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• pp.6201-6213
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• 2015

본 연구의 목적은 경증 알츠하이머 환자를 대상으로 현실감각과 시간차 회상 훈련을 적용한 CERAD-K형 인지재활 프로그램의 효과를 밝히는 것이다. 연구에 사용된 도구는 CERAD-K 신경심리 검사로, 하위 영역으로 보스턴 이름 대기, 간이 정신 상태, 단어 목록 회상, 구성 행동으로 구성되어 있다. 연구 설계는 비동등성 대조군 전 후 실험 설계이다. 연구는 경기도의 G 보건소에 등록된 경증 알츠하이머 치매 환자를 편의 표집 하여 실험군 32명과 대조군 53명을 대상으로 하였다. 실험군은 2014년 9월 1일 부터 9월 30일까지 매주 화요일과 금요일에 두 팀으로 나누어 오전 10시부터 11시, 오후 2시부터 3시까지 한 팀당 16명씩 주 2회씩 8회의 인지재활 프로그램을 실시하였다. 대조군은 해당 보건소의 일상 프로그램에 참여하였다. 자료는 SPSS WIN 21.0 program을 이용하여 분석하였다. 연구 결과 단어 목록 회상(F=.75 p>.05)을 제외한 보스턴 이름 대기(F=3.22, p<.001), 간이 정신 상태(F=5.92, p<.001), 구성 행동(F=4.67, p<.001)이 유의하게 향상되어 현실감각과 시간차 회상훈련을 적용한 CERAD-K형 인지재활 프로그램은 경증 알츠하이머 치매 환자의 인지 기능을 향상 시키는 것으로 나타났다.

• 대한간호학회지
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• 제46권3호
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• pp.349-363
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• 2016

Purpose: This study was done to develop a internalized stigma reducing program based on cognitive-behavioral therapy and appropriate for patients with schizophrenia and to evaluate its effectiveness. Methods: The study design was a mixed method research. Qualitative study, 13 patients with schizophrenia who had experience in overcoming stigma were purposively chosen for interviews and data were analyzed using Giorgi method. Quantitative study, 64 patients with schizophrenia (experimental group =32, control group =32) were recruited. The cognitive-behavioral therapy-based program for reducing internalized stigma in patients with schizophrenia was provided for 8 weeks (12 sessions). Data were collected from June. 20, 2013 to Feb. 14, 2014. Quantitative data were analyzed using ${\chi}^2-test$, t-test, repeated measures ANOVA with the SPSS program. Results: Qualitative results, from the experience of coping with stigma in patients with schizophrenia seventeen themes and five themes-clusters were drawn up. Quantitative results showed that internalized stigma, self-esteem, mental health recovery and quality of life were significantly better in the experimental group compared to the control group. Conclusion: Study findings indicate that this program for reducing internalized stigma in patients with schizophrenia is effective and can be recommended as a rehabilitation program intervention to help patients with schizophrenia to cope with internalized stigma.