• Title/Summary/Keyword: Group Flow

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Improved Myoardial Protection by Addition of Fructose-1.6-diphosphate to Crystalloid Cardioplegic Solution in the Isolated Working Rat Heart (흰쥐의 적출 작업성 심장에서 허혈성 심정지시 Fructose-1.6-diphosphate(FDP)의 심근보호 작용)

  • 나국주
    • Journal of Chest Surgery
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    • v.23 no.4
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    • pp.646-653
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    • 1990
  • Currently numerous methods are in use for myocardial protection from the ravages of ischemia and hypoxia. This study was designed to compare with FDP-GIK[Group II, n=8] and GIK cardioplegic solution[Group I, n=8] in ability of myocardial protection and was examined in the isolated working rat heart subjected to long period[120 min] of hypothermic[10 - 15K] ischemic arrest with multidose[every 30 min] cardioplegic infusion. During postischemic reperfusion period 20 min, hemodynamic functions[aortic flow, coronary flow, peak aortic pressure, cardiac output, heart rate], biochemical enzymatic & electrical activities were evaluated. The time from onset of reperfusion to the return of regular sinus rhythm was significantly reduced from 87$\pm$3 sec to 17$\pm$2 sec[P<0.05]. The postischemic recovery of aortic flow was better in the group II [95.1$\pm$3.3% of its preischemic control level] than in the Group I [75.4$\pm$6.8%] [P<0.05]. Cardiac output and stroke volume was also better in the group[91.3$\pm$1.6%, 89.4$\pm$2.6%, respectively] than in the Group I [79.1$\pm$3.7%, 77.0$\pm$4.8%, respectively] [P<0. 05]. Creatine kinase leakage was also significantly reduced from 33.8$\pm$4.9 IU /10 min / gm * dry weight to 15.4$\pm$3.6 IU /10 min /gm * dry weight[P<0.05]. It is suggested that adding FDP to GIK cardioplegic solution improves its ability to protect the heart against long period of hypoxic ischemia.

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CHANGE OF BLOOD VISCOSITY AND DEFORMABILITY IN ORAL SQUAMOUS CELL CARCINOMA PATIENTS (구강편평세포암종 환자에서의 혈액 점도와 혈액 변형성 변화에 대한 연구)

  • Yun, Pil-Young;Myoung, Hoon;Lee, Jong-Ho;Choung, Pill-Hoon;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.3
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    • pp.181-185
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    • 2004
  • Malignant tumor have hypoxic cell fraction, which makes radio-resistant and hypoxia in tumor is a result from the blood flow decrease caused by increase in blood flow resistance. Blood viscosity increase is major factor of increased blood flow resistance and it could be attributed to the decrease in blood deformability index. For the evaluation of the change of blood viscosity and blood deformability in oral squamous cell carcinoma, we perform the test of the change of those factors between the normal control group and oral squamous cell carcinoma cell patient group. Relative viscosity measured against distilled water was $5.25{\pm}0.14$ for normal control group, and $5.78{\pm}0.26$ for the SCC patient group and there was statistical significance between the groups. However, there was no significant difference between the groups in blood viscosity between the groups by tumor size (T1+T2 vs T3+T4). Also, there was no significant difference between the normal control group and SCC patient group in blood deformability index and between the groups by tumor size (T1+T2 vs T3+T4). Increase in blood viscosity was confirmed with this study and it can be postulated that modification blood viscosity might contribute to decrease of hypoxia fraction in oral squamous cell carcinoma, thus improve the effect of radiotherapy and it can be assumed that the main factor of blood viscosity increase is not decrease of blood deformability in oral squamous cell carcinoma.

Electrochemical Studies of Carbon Felt Electrode Modified Under Airless Conditions for Redox Flow Batteries

  • Noh, Tae Hyoung;Kim, Min Young;Kim, Da Hye;Yang, Seung Hoon;Lee, Jong Ho;Park, Hong Sik;Noh, Hee Sook;Lee, Moo Sung;Kim, Ho Sung
    • Journal of Electrochemical Science and Technology
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    • v.8 no.2
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    • pp.155-161
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    • 2017
  • Carbon felts were prepared under various thermal conditions to improve the electrochemical properties of vanadium redox flow batteries. The number of C-O and/or C-OH functional groups on the surface of the electrodes treated under airless conditions was much larger than that of the untreated and partially oxygen-treated electrodes. The carbon felt treated under airless conditions had the lowest surface area. The overall kinetic properties of the redox reaction were greatly improved for the carbon felt treated under airless conditions; i.e., the reversibility of the anodic and cathodic reactions associated with the $VO_2{^+}/VO^{2+}$ couple became more reversible. Single-cell tests indicated that the carbon felt exhibited an excellent discharge capacity of $3.1Ah{\cdot}g^{-1}$ at $40mA{\cdot}cm^{-2}$, and the corresponding Coulombic, voltage, and energy efficiencies were 89.5%, 91.8%, and 82.2%, respectively.

Effects of Flow Excitation on the Nitrogen Oxide Emission of a Non-Premixed Flame (유동장 자극이 화염의 질소산화물 배출에 미치는 영향)

  • 이기만
    • Fire Science and Engineering
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    • v.18 no.2
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    • pp.34-40
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    • 2004
  • The effects of external flow excitation with various frequencies and amplitudes on the flame behavior and pollution emission characteristics from a laminar jet flame are experimentally investigated. Measurements of $NO_x$ emission indices ($EINO_x$), performed in vertical lifted flame like turbulent with various exciting amplitude at a constant resonance frequency, have been conducted. It was also conducted to investigate the effects of excited frequency at a constant exciting amplitude on $NO_x$ emissions with a various frequency ranged 0 Hz to 2 KHz. From the vertical lifted turbulent flame of the excited jet with resonance frequency by strong excitation was shown that the dependence of $NO_x$ emission could be categorized into three groups Group I of long flame length with high disturbances yielding high $NO_x$ emission, Group II of intermediate flame length and relative narrow flame volume with low disturbance yielding low $NO_x$ emission and Group III of long flame length and large flame volume with high time & space disturbances behaviour yielding high $NO_x$ emission.

Morphological Patterns of the Anterior Median Fissure in the Cervical Spinal Cord Evaluated by Computed Tomography After Myelography

  • Oichi, Yuki;Hanakita, Junya;Takahashi, Toshiyuki;Minami, Manabu;Kawaoka, Taigo;Funakoshi, Yusuke;Kawauchi, Takeshi;Ohtake, Yasufumi
    • Neurospine
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    • v.15 no.4
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    • pp.388-393
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    • 2018
  • Objective: Computed tomography following myelography (CTM) revealed an unusual flow of contrast dye into the anterior median fissure (AMF) in a patient with cervical spondylotic myelopathy. Since then, several AMF configurations have been observed on CTM. Therefore, we evaluated morphological patterns of the AMF on CTM and investigated the significance and mechanisms of contrast dye flow into the AMF. Methods: Morphological patterns of the AMF on CTM were examined in 79 patients. Group A (24 patients) underwent surgery because of symptomatic cervical myelopathy. Group B (43 patients) had no clinical symptoms but showed spinal cord compression on CTM. Group C (12 patients), who showed neither clinical symptoms nor cord changes, underwent CTM for lumbar lesion evaluation. AMF patterns were classified into 4 types according to their configurations on CTM (reversed T, Y, V, and O types). Results: In group B, the reversed T type and Y type appeared significantly more often near the compressed portion (p<0.001). A similar tendency was seen in group A. The V and O types were most frequently observed in group C (p<0.001). Conclusion: On CTM, contrast dye tends to flow into the AMF of the cervical cord when the spinal cord is compressed. We speculate that there may be 3 possible mechanisms for this phenomenon: deformation of the epipial layer of the AMF due to cervical cord compression, AMF dilatation due to atrophy of the anterior funiculus or anterior horn, and temporary AMF dilatation when it becomes an alternative route for cerebrospinal fluid circulation.

Neurological Improvement after Cranioplasty in Patients with Surgical Bony Defects : The Usefulness of Acetazolamide Activated $^{99m}Tc-HMPAO$ SPECT

  • Seo, Won-Duck;Kim, Young-Don;Hong, Dae-Young;Kim, Dae-Hyun;Choi, Gi-Hwan;Yeo, Hyung-Tae
    • Journal of Korean Neurosurgical Society
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    • v.40 no.6
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    • pp.434-440
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    • 2006
  • Objective : The purpose of this study is to examine the influence of cranioplasty on dynamics of cerebral blood flow[CBF] and cerebrovascular reserve capacity[CVRC], and to investigate the usefulness of single photon emission computed tomography [SPECT] as a prognostic factor for neurological improvement after cranioplasty. Methods : Between March 2003 and December 2005, a prospective study was performed on 24 patients who had undergone total 25 cranioplasty operations. Cerebral blood flow velocities in the middle cerebral artery[MCA] and internal carotid artery[ICA] were obtained by transcranial Doppler ultrasonography[TCD]. The CVRC was assessed by SPECT in the natural state and after stimulation with 1g of acetazolamide. Neurological improvement after cranioplasty was compared between patients who showed hyperactivity to acetazolamide-activated SPECT [Group 1, n=7] and hypoactivity to acetazolamide-activated SPECT [Group 2, n=17]. These measurements were obtained two weeks prior to and two weeks after cranioplasty. Results : The blood flow velocities at the opposite site to the cranioplasty as well as at the cranioplasty site were significantly increased [P<0.05]. Compared with Group 2, there was significant increase in CBF and neurological improvement after cranioplasty in Group 1. Conclusion : Among patients with surgical bony defects, the patients who had normal reactivity of the CVRC showed a significant increase in CBF and neurological improvement after cranioplasty. The authors suggest that CVRC measurement prior to surgery may be an important prognostic factor for neurological improvement after cranioplasty.

Analysis of Regional Centrality by Investigating Direct and Indirect Flows of Commuters (통근통행에 의한 직·간접 흐름을 이용한 지역의 중심성 분석)

  • Lee, Jong-Sang;Seo, Ducksu
    • Journal of Agricultural Extension & Community Development
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    • v.27 no.3
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    • pp.125-134
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    • 2020
  • The regional centrality plays a very important role in national and regional planning and it is measured by data such as people, goods, and information flows among regions. The inter-regional flows are usually considered by only direct flows, yet indirect flows, which are generated accordingly from direct flows, are not critically considered. Most centrality studies have also hardly reflected the indirect flow in the network analysis. This study demonstrates the significance of the indirect flows to enhance accuracy of the regional centrality. The nationwide dataset of inter-regional commuter traffic matrix is used in this study and analysed into two groups; one to consider only direct flow and the other both direct and indirect flows. The results indicate remarkable differences of centrality raking between two groups such as Yeongam of Jeonnam Province(+60th), Eumseong of Chungbuk Province(+57th), Gwacheon of Gyeonggi Province (-35th), and Nowon of Seoul (-32nd). It clearly shows the significant influence of indirect flow for regional centrality study. This also reveals regional centrality ranking in Korea by considering direct and indirect flows of commuters. Jung, Gangnam, and Jongno of Seoul are categorized in the highest rank group and Ulleung of Gyeongbuk, Ongjin of Incheon, and Jindo of Jeonnam are in the lowest group. The top group includes seven districts of Seoul, two of Busan, and one of Gyeonggi Province. The bottom group includes mostly island and costal areas. As this study shows an accurate method of centrality measurement, it has a significant implication to lead an effective regional planning.

Influence on Vertebral Artery and Basilar Artery Blood flow by Cervical CHUNA Manual Therapy (경추 추나요법이 추골동맥과 기저동맥 혈류에 미치는 영향)

  • Shin, Byung-Cheul;Kim, Do-Hwan;Kim, Sang-Don;Song, Yung-Sun
    • The Journal of Korea CHUNA Manual Medicine
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    • v.1 no.1
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    • pp.45-53
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    • 2000
  • Objectives : CHUNA therapy that removes compression of dislocated vertebral bones has positive effect, but sometimes improper CHUNA manual therapy may give rise to negative effect. The aim of this study is to make sure that cervical CHUNA manual therapy give positive effect or negative effect to the blood flow velocity of vertebral artery(VA) and basilar artery(BA) by Trancranial Doppler sonography(TCD). Methods : We performed TCD study on 20patients(male 5, female 15, mean ages 38.5 years) with diagnosis like cervical movement related disorder, headache or dizziness. After we measured mean blood flow velocity(Vm) of VA and BA before cervical CHUNA therapy(Pre-CCT) and after cervical CHUNA therapy(Post-CCT), statistically evaluated the results. Results: The patients received cervical CHUNA therapy for TA sequel, HIVD of cervical spine, headache, dizziness, neck stiffness etc. VA Vm was $31.9{\pm}8.0cm/sec$ before CHUNA therapy, but significantly increased $35.0{\pm}8.7cm/sec$ after CHUNA therapy (p < 0.05). But, there was no significant variation of BA Vm between $41.8{\pm}7.5cm/sec$ Pre-CCT and $41.2{\pm}8.5cm/sec$ Post-CCT(p>0.05). Though VA Vm slightly increased after CHUNA therapy in normal range group, there was no significant variation between VA Vm Pre-CCT and VA Vm Post~CCT. In VA Vm decrease group, VA Vm significantly increased after CHUNA therapy(p<0.05). But, there was no significant variation of BA Vm between Pre-CCT and Post-CCT in BA Vm normal range group and BA Vm decrease group(p>0.05). Conclusions: These findings suggest that cervical CHUNA manual therapy have positive effect on blood flow velocity of VA and BA.

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The Effect of Distal Aortic Pressure on Spinal Cord Perfusion in Rats

  • Park, Sung-Min;Cho, Seong-Joon;Ryu, Se-Min;Lee, Kyung-Hak;Kang, Gu
    • Journal of Chest Surgery
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    • v.45 no.2
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    • pp.73-79
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    • 2012
  • Background: Aortic cross clamping is associated with spinal cord ischemia. This study used a rat spinal cord ischemia model to investigate the effect of distal aortic pressure on spinal cord perfusion. Materials and Methods: Male Sprague-Dawley rats (n=12) were divided into three groups. In group A (n=4), the aorta was not occluded. In groups B (n=4) and C (n=4), the aorta was occluded. In group B the distal aortic pressures dropped to around 20 mmHg. In group C, the distal aortic pressure was decreased to near zero. The carotid artery and tail artery were cannulated to monitor the proximal aortic pressure and the distal aortic pressure. Fluorescent microspheres were used to measure the regional blood flow in the spinal cord. Results: After aortic occlusion, blood flow to the cervical spinal cord showed no significant difference among the three groups. In groups B and C, the thoracic and lumbar spinal cord and renal blood flow decreased. No microspheres were detected in the thoracic and lumbar spinal cord of group C. Conclusion: The spinal cord blood flow is dependent on the distal aortic pressure after thoracic aortic occlusion.

Dentin moisture conditions strongly influence its interactions with bioactive root canal sealers

  • Ozlek, Esin;Gunduz, Huseyin;Akkol, Elif;Neelakantan, Prasanna
    • Restorative Dentistry and Endodontics
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    • v.45 no.2
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    • pp.24.1-24.9
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    • 2020
  • Objectives: It is known that bioactive materials interact with the dentin to undergo biomineralization. The exact role of moisture in this interaction is unknown. Here, we investigate the effects of dentin moisture conditions on the dislocation resistance of two bioactive root canal sealers (MTA Fillapex [Angelus Solucoes Odontologicas] and GuttaFlow BioSeal [Colténe/Whaledent AG]) at 3 weeks and 3 months after obturation. Materials and Methods: Mandibular premolars (n = 120) were prepared and randomly divided into 3 groups based on the dentin condition: group 1, dry dentin; group 2, moist dentin; group 3, wet dentin. Each group was divided into 2 subgroups for root canal filling: MTA Fillapex and GuttaFlow BioSeal. Dislocation resistance was evaluated by measuring the push-out bond strength at 3 weeks and 3 months. Failure modes were examined under a stereomicroscope. Data were statistically analyzed by Kruskal-Wallis test with a significance level of 5%. Results: Moist dentin resulted in higher bond strength values for both materials at both time points. This was significantly higher than wet and dry dentin for both the sealers at the 3 months (p < 0.05), while at 3 weeks it was significant only for GuttaFlow Bioseal. The different moisture conditions demonstrated similar trends in their effects on the dislocation resistance of the 2 root canal sealers. Conclusions: The dentin moisture conditions had a significant impact on its interaction with the bioactive materials tested. Maintaining moist dentin, but not dry or wet dentin, may be advantageous before the filling root canals with bioactive sealers.