• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.549-549
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• 2012

Early detection of cancer biomarkers in the blood is of vital importance for reducing the mortality and morbidity in a number of cancers. From this point of view, immunosensors based on nanowire (NW) and carbon nanotube (CNT) field-effect transistors (FETs) that allow the ultra-sensitive, highly specific, and label-free electrical detection of biomarkers received much attention. Nevertheless 1D nano-FET biosensors showed high performance, several challenges remain to be resolved for the uncomplicated, reproducible, low-cost and high-throughput nanofabrication. Recently, two-dimensional (2D) graphene and reduced GO (RGO) nanosheets or films find widespread applications such as clean energy storage and conversion devices, optical detector, field-effect transistors, electromechanical resonators, and chemical & biological sensors. In particular, the graphene- and RGO-FETs devices are very promising for sensing applications because of advantages including large detection area, low noise level in solution, ease of fabrication, and the high sensitivity to ions and biomolecules comparable to 1D nano-FETs. Even though a limited number of biosensor applications including chemical vapor deposition (CVD) grown graphene film for DNA detection, single-layer graphene for protein detection and single-layer graphene or solution-processed RGO film for cell monitoring have been reported, development of facile fabrication methods and full understanding of sensing mechanism are still lacking. Furthermore, there have been no reports on demonstration of ultrasensitive electrical detection of a cancer biomarker using the graphene- or RGO-FET. Here we describe scalable and facile fabrication of reduced graphene oxide FET (RGO-FET) with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}$ 1-antichymotrypsin (PSA-ACT) complex, in which the ultrathin RGO channel was formed by a uniform self-assembly of two-dimensional RGO nanosheets, and also we will discuss about the immunosensing mechanism.

• Membrane Journal
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• v.27 no.2
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• pp.167-181
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• 2017

Graphene-based materials have been considered as a promising membrane material, due to its easy processability and atomic thickness. In this study, we studied on gas permeation behavior in few-layered GO membranes prepared by spin-coating method. The GO membrane structures were varied by using different GO flake sizes and GO solutions at various pH levels. The GO membranes prepared small flake size show more permeable and selective gas separation properties than large one due to shortening tortuosity. Also gas transport behaviors of the GO membranes are sensitive to slit width for gas diffusion because the pore size of GO membranes ranged from molecular sieving to Knudsen diffusion area. In particular, due to the narrow pore size of GO membranes and highly $CO_2$-philic properties of GO nanosheets, few-layered GO membranes exhibit ultrafast and $CO_2$ selective character in comparison with other gas molecules, which lead to outstanding $CO_2$ capture properties such as $CO_2/H_2$, $CO_2/CH_4$, and $CO_2/N_2$. This unusual gas transport through multi-layered GO nanosheets can explain a unique transport mechanism followed by an adsorption-facilitated diffusion behavior (i.e., surface diffusion mechanism). These findings provide the great insights for designing $CO_2$-selective membrane materials and the practical guidelines for gas transports through slit-like pores and lamellar structures.

• Journal of Electrochemical Science and Technology
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• v.8 no.4
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• pp.307-313
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• 2017

In this paper we report an electrochemical sensor based on ZnO-functionalized graphene oxide nanocomposite (ZnO-GO) for the sensitive determination of the cabergoline. Cabergoline electrochemical behaviors were investigated by cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV). The modified electrode shows electrocatalytic activity toward cabergoline oxidation in phosphate buffer solution (PBS) (pH 7.0) with a reduction of the overpotential of about 180 mV and an increase in peak current. The DPV data showed that the obtained anodic peak currents were linearly dependent on the cabergoline concentrations in the range of $1.0-200.0{\mu}M$, with the detection limit of $0.45{\mu}M$. The prepared electrode was successfully applied for the determination of cabergoline in real samples.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.382.2-382.2
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• 2014

We explain a method to fabricate multi-layered transparent conductive films (TCF) using graphene oxide (GO), copper powder and polyurethane (PU) solution. The flexible graphene nanosheets (GNSs) serve as nanoscale connection between conductive copper nanoparticles (CuNps) and PU nanofibers, resulting in a highly flexible TCF. To fabricate conductive films with high transmittance, polyurethane (PU) nanofibers were used for a conductive network consisting of CuNps and GNSs (CuNps-GNSs). In this experiment, copper powder and graphene oxides were mixed in deionized water with the ultrasonication for 2 h. NaBH4 solution is used as a reduction agents of CuNps and GNSs (CuNps-GNSs) under a nitrogen atmosphere in the oil bath at 100% for 24 h to mixed. The purified and dispersed CuNp-GNS were obtained in deionized water, and diluted to a 10wt.% based on the contents of GNSs. Polyurethane (PU) nanofibers on a PET substrate were formed by electrospinning method. PET slides coated with the PU nanofibers were immersed into CuNp-GNS solution for several second, rinsed briefly in deionized water, and dried to obtain self-assembled CuNp-GNS/PU films. The morphology of the multi-layered films were characterized with a field emission scanning electron microscope (FE-SEM, Hitachi S-4700) and atomic force microscope (AFM, PSIA XE-100). The electrical property was analysed by the I-V measurement system and the optical property was measured by the UV/VIS spectroscopy.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.431-431
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• 2011

Graphene, two dimensional sheet of sp2-hybridized carbon, has attracted an enormous amount of interest due to excellent electrical, chemical and mechanical properties for the application of transparent conducting films, clean energy devices, field-effect transistors, optoelectronic devices and chemical sensors. Especially, graphene is promising candidate to detect the gas molecules and biomolecules due to the large specific surface area and signal-to-noise ratios. Despite of importance to the disease diagnosis, there are a few reports to demonstrate the graphene- and rGO-FET for biological sensors and the sensing mechanism are not fully understood. Here we describe scalable and facile fabrication of rGO-FET with the capability of label-free, ultrasensitive electrical detection of a cancer biomarker, prostate specific antigen/${\alpha}1$-antichymotrypsin (PSA-ACT) complex, in which the ultrathin rGO sensing channel was simply formed by a uniform self-assembly of two-dimensional rGO nanosheets on aminated pattern generated by inkjet printing. Sensing characteristics of rGO-FET immunosensor showed the highly precise, reliable, and linear shift in the Dirac point with the analyte concentration of PSA-ACT complex and extremely low detection limit as low as 1 fg/ml. We further analyzed the charge doping mechanism, which is the change in the charge carrier in the rGO channel varying by the concentration of biomolecules. Amenability of solution-based scalable fabrication and extremely high performance may enable rGO-FET device as a versatile multiplexed diagnostic biosensor for disease biomarkers.

• Particle and aerosol research
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• v.9 no.2
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• pp.51-57
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• 2013

A graphene(GR)-$TiO_2$ composite was synthesized from colloidal mixture of graphene oxide(GO) nanosheets and $TiO_2$ nanoparticles by an aerosol assisted self-assembly. The morphology, specific surface area and pore size of asprepared GR-$TiO_2$ composite were characterized by FE-SEM, BET, and BJH respectively. The shape of GR-$TiO_2$ composite was spherical. The average particle size was 0.5-1 ${\mu}m$ in diameter and the pore diameter ranged 20-50 nm. Photovoltaic characteristics of a mixture of the GR-$TiO_2$ and $TiO_2$ nanoparticles were measured by a solar simulator under simulated solar light. The highest photoelectric conversion efficiency of the mixture photoanode was 5.1%, which was higher than that of $TiO_2$ photoanode.

• Applied Chemistry for Engineering
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• v.29 no.5
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• pp.533-540
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• 2018

Graphene has been reported to be an excellent lubricant additive that reduces friction and wear when coated on the surface of various materials or when dispersed in lubricants as an atomic thin material with the low surface energy. In this study, alkyl functionalized graphene oxide (FGO) nanosheets for oil-based lubricant additives were prepared by using three types of alkyl chloride chemicals (butyl chloride, octyl chloride, and tetradecyl chloride). The chemical and structural properties of the synthesized FGOs were analyzed by Fourier transform infrared (FT-IR), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscope (SEM), and transmission electron microscope (TEM). The synthesized FGOs were dispersed at 0.02 wt% in PAO-0W40 oil and its tribological characteristics were investigated using a high frequency friction/wear tester. The friction coefficient and the wear track width of poly alpha olefin (PAO) oil added with FGO-14 were tested by a ball-on-disk method, and the measured results were reduced by ~5.88 and ~3.8%, respectively compared with those of the conventional PAO oil. Thus, it was found that the wear resistance of PAO oil was improved. In this study, we demonstrated the successful functionalization of GO as well as the improvement of dispersion stability and tribological characteristics of FGOs based on various alkyl chain lengths.

• Membrane Journal
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• v.30 no.1
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• pp.38-45
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• 2020

Although Lithium metal battery (LMB) has a very large theoretical capacity, it has a critical problem such as formation of dendrite which causes short circuit and short cycle life of the LMB. In this study, PDMS/GO composite with evenly dispersed graphene oxide (GO) nanosheets in poly (dimethylsiloxane) (PDMS) was synthesized and coated into a thin film, resulting in the effect that can physically suppress the formation of dendrite. However, PDMS has low ion conductivity, so that we attained improved ion conductivity of PDMS/GO thin film by etching technic using 5wt% hydrofluoric acid (HF), to facilitate the movement of lithium (Li) ions by forming the channel of Li ions. The morphology of the PDMS/GO thin film was observed to confirm using SEM. When the PDMS/GO thin film was utilized to lithium metal battery system, the columbic efficiency was maintained at 87.4% on average until the 100^th cycles. In addition, voltage profiles indicated reduced overpotential in comparison to the electrode without thin film.

• Korean Chemical Engineering Research
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• v.60 no.4
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• pp.574-581
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• 2022

Nanofibers comprising reduced graphene oxide (rGO) and Mo₂C/Mo₂N nanoparticles (Mo₂C/Mo₂N rGO NFs) were prepared for a functional interlayer of Li-S batteries (LSBs). The well-dispersed Mo₂C and Mo₂N nanoparticles in the nanofiber structure served as active polar sites for efficient immobilization of dissolved lithium polysulfide. The rGO nanosheets in the structure also provide conductive channels for fast ion/electron transport during charging-discharging and ensured reuse of lithium polysulfide during redox reactions through a fast charge transfer process. As a result, the cell assembled with Mo₂C/Mo₂N rGO NFs-coated separator and pure sulfur electrode (70 wt% of sulfur content and 2.1 mg cm^-2 of sulfur loading) showed a stable discharge capacity of 476 mA h g^-1 after 400 charge-discharge cycles at 0.1 C. Furthermore, it exhibited a discharge capacity of 574 mA h g^-1 even at a high current density of 1.0 C. Therefore, we believe that the proposed unique nanostructure synthesis strategy could provide new insights into the development of sustainable and highly conductive polar materials as functional interlayers for high performance LSBs.

• Journal of Digital Convergence
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• v.18 no.4
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• pp.309-314
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• 2020

Polymethyl methacrylate (PMMA) is concerned with promoting oral infection due to its low antibacterial activity. To overcome this, the nanoparticles of Ag-MSN, nGO, and CNP were mixed with MMA liquid in a weight ratio of 0, 0.25, 0.5, 1.0, 2.0% compared to resin powder using Orthocryl from Dentarum, a calibration resin, and then instructed by the manufacturer. Accordingly, a specimen for calibration was prepared by mixing PMMA: MMA (1.2: 1) ratio, and physical properties of the calibration resin, antifungal experiments, and statistical analysis were performed. As a result of antibacterial experiments, the antibacterial properties of Ag-MSN increased. In nGO, the antibacterial adhesive effect increased hydrophilicity, not a change in surface roughness. The higher the CNP concentration, the higher the antibacterial activity. This suggests its potential usefulness as an antibacterial dental material for orthodontic devices and temporary restorations.