• 대한약침학회지
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• 제20권3호
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• pp.173-178
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• 2017

Objectives: Medicinal plants are vital sources of bioactive compounds that are useful for the treatment of patients with snake bites or are indirectly applicable for boosting the effects of conventional serum therapy. These plants are being used traditionally by local healers and tribes for the treatment of patients with snake bites and therefore can be used as an alternative against snake envenomation. Scientifically, using the secondary metabolites of plants to neutralize venom enzymes has an extra benefit of being based on traditional knowledge; also, the use of such metabolites for the treatment of patients with snake bites is cheaper and the treatment can be started sooner. Methods: All the available information on various secondary metabolites exhibiting venom neutralizing ability were collected via electronic search (using Google books, Pubmed, SciFinder, Scirus, Google Scholar, and Web of Science) and articles of peer-reviewed journals. Results:Recent interest in different plant has focused on isolating and identifying of different phytoconstituents that exhibit Phospholipase A2 activity and other venom enzyme neutralizing ability. In this support convincing evidence in experimental animal models are available. Conclusion: Secondary metabolites are naturally present, have no side effect, are stable for a long time, can be easily stored, and can neutralize a wide range of snake enzymes, such as phospholipase A2, hyaluronidase, protease, L-amino acid oxidase, 5'nucleotidase, etc. The current review presents a compilation of important plant secondary metabolites that are effective against snake venom due to enzyme neutralization.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2021년도 학술발표회
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• pp.455-455
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• 2021

The Life Cycle Assessment (LCA) as an environmental impact assessment tool has received increasing attention over the years. Unlike the water footprint (WF) and carbon footprint (CF) assessments whose focus is only on a single environmental aspect, the LCA systematically analyzes the different impacts along the entire life cycle, making possible the identification of potential environmental tradeoffs. In Korea, LCA has drawn much attention from both industry and academia since the mid-90s. However, the level of Korea-related LCA studies with respect to different sectors in the past 20 years has not been analyzed. This study, therefore, sought to assess the status of environmental Life Cycle Assessment (LCA) studies in Korea, with a view to understanding the current level of sustainability reporting and identify potential research gaps. Online searches of English written articles published between 2000 and 2019 were conducted on Google, Google scholar, Scopus, and Web of Science databases using the Keywords "life cycle assessment", "lca", and "Korea." At the end of the search, about 88 LCA related studies were identified for Korea within the study period. Majority of these studies focused on the construction (49%) and energy (31%) sectors with fewer environmental studies on the transportation (9%), manufacturing (8%), agriculture (2%), and information and communication (1%) industries. Based on publication trend, results show that LCA studies in Korea have been on the rise in the past 20 years, even though the number of publications has not followed a constant pace. In comparison with the economic sectors of the country, reports show an inadequacy in the coverage of major industries of growing economic relevance like the tourism, health, and agriculture, suggesting a need to further increase and improve LCA related studies in these sectors.

• Journal of Hospice and Palliative Care
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• 제22권3호
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• pp.105-116
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• 2019

목적: 소아청소년 호스피스 완화의료(이하 소아완화의료)는 생명을 위협하는 질환을 가진 소아청소년의 삶의 질을 향상시기 위한 총체적 돌봄 철학이자 실무의 표준이다. 국내에서는 2018년 7월 국가 지원의 소아완화의료 시범사업을 도입하였는데, 소아완화의료의 발전 방향을 제시하기 위해 국외 선진국의 소아완화의료 제공체계를 고찰하였다. 방법: 소아완화의료 제공 수준을 검토하여 영국, 미국, 일본, 싱가포르를 대상으로 선정하였다. 소아완화의료 제공체계를 다룬 국내외 학술지 등 문헌을 통합적으로 고찰하고 현지 전문가의 자문과 현지 방문조사를 수행하였다. 1990년 이후 영어, 일본어로 발간된 문헌을 중심으로 PubMed, Google, Google Scholar에서 검색하여 학술지, 정책보고서 등을 참고하였다. 각국의 소아완화의료 발전과정, 정책, 재정 모델, 대상 기준, 전달 체계, 질 관리 체계에 대해 분석하였다. 결과: 영국은 지역사회의 독립형 소아전문 완화의료기관이 일차 의료체계와 협력하며 어린이병원의 전문 소아완화의료 자문팀과 의뢰와 자문을 주고받는다. 미국은 병원기반의 전문 소아완화의료 자문팀을 중심으로 지역사회의 호스피스기관, 가정의료기관이 네트워크를 구축하고 돌봄 코디네이터를 지정하여 소아완화의료를 제공한다. 일본은 완화의료, 재택의료, 장애아동 및 만성질환아동 지원체계에서 완화의료 성격의 서비스를 제공한다. 싱가포르는 소아전문 가정 완화의료 단체가 어린이병원의 전문 자문팀과 협력하여 높은 지리적 접근성을 토대로 중추적으로 완화의료를 제공한다. 결론: 국외의 제공체계를 참고하고 국내의 현장의 요구를 반영하여 소아완화의료의 제공체계를 정비하여 미충족 요구가 발생하지 않도록 한국 소아청소년 호스피스완화의료를 최적화해 나가야 한다.

• 대한감각통합치료학회지
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• 제21권1호
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• pp.59-73
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• 2023

목적 : 본 연구는 COVID-19 상황 속 자폐스펙트럼 장애아동의 놀이 활동과 관련된 문헌을 분석하여 재난으로 인한 아동의 놀이 활동 참여 변화를 살펴보고자 하였다. 연구방법 : Arskey와 O'Malley가 제시한 주제범위 문헌고찰의 5단계에 따라 진행되었다. COVID-19가 발표된 2020년 3월부터 2022년 8월까지 CINAHL, PubMed, ERIC, MEDLINE, Google scholar 데이터베이스와 Google 검색엔진을 통해 영문 문헌과 웹사이트 정보를 검색하였다. 문헌의 출판연도, 연구가 이루어진 국가, 연구유형, 대상자 연령, 대상자 수, 연구 결과 등의 10가지 항목에 따라 데이터를 정리하였다. 양적 자료를 통해 관련 주제의 일반적 특성을 알아보았고, 주제 분석을 통해 COVID-19로 인한 아동의 놀이 양상 변화를 확인하였다. 결과 : 437개의 문헌 및 152개의 웹사이트 정보를 검토하여 최종적으로 6개의 문헌이 분석되었다. 분석된 연구는 다양한 나라와 분야의 전문가들에 의해 수행되었다. 문헌에서 공통으로 강조된 5가지 주제는 COVID-19로 인한 자폐스펙트럼 장애아동의 실외 놀이 감소, 스크린 이용 시간 증가, 가족 간 시간 증가, 감각적 어려움, 그리고 연구자가 권고하는 서비스로 나타났다. 결론 : 본 연구에서는 재난 상황 시 자폐스펙트럼 장애아동이 경험하는 놀이 활동 참여의 어려움을 해결하기 위해 주양육자와 자녀가 함께할 수 있는 공동 미디어 참여, 부모 행동 전략 교육 등의 비대면 프로그램을 제안한다. 연구 결과는 향후 재난 상황 시 장애아동의 놀이 활동의 중요성을 강조하고, 이를 지원하기 위한 작업치료사의 역할과 서비스 지침을 체계화하는 데에 기초자료로 활용될 수 있다.

• 한국간호교육학회지
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• 제17권3호
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• pp.395-404
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• 2011

Purpose: The purpose of this paper was to analyze research papers using movies and to introduce a practical instruction in cinema education for nurse educators in Korea. Method: The computerized database of PubMed, Google scholar, NDSL, CINAHL, and PsychINFO were used to generate relevant literature. Sixteen studies were published between 1990 and 2011 and were included in this review. These papers were analyzed using the matrix method suggested by Garrad (2007). Results: The first paper using movies in nursing education was performed in 1995. There were 16 studies on this issue and classified into one qualitative and 15 quantitative research. Because psychiatric mental health nursing was the main course, movies relating to mental illness were mainly considered. Most papers used questionnaires developed by researchers and discussions regarding the course. The key findings in these papers were all positive. Conclusion: The critics and syntheses in these papers emerged into seven overarching merits of cinema education and that lead to conduct cinema education to deepen students' understanding and to evoke empathy, critical thinking, entertainment, and intimacy. In addition, cinema education was safe and economical. This study recommends discovering suitable films and developments in both instruction process and educational evaluation tools.

• 혜화의학회지
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• 제24권2호
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• pp.65-83
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• 2016

Objectives : The purpose of this study is to present the clinical practice guidelines for colorectal cancer through the analysis of existing clinical practice guidelines and randomised clinical trials (RCTs) in Western and Chinese medicine. Methods : The data related to Western and Oriental medical treatment of colorectal cancer were collected using various search engines such as Google Scholar, KIOM OASIS, PUBMED and Jisan library of Daejeon university. Results & Discussion : Colorectal cancer is the third most common cancer in Korea. In recent studies, applying combined oriental and western medicine can improve the survival, quality of life, immune function, and suppress of tumor growth in colorectal cancer. However there isn't still an objective and systemic clinical guideline for colorectal cancer, so we have difficulty in clinical application. This study will be a preliminary study to establish clinical practice guidelines of Korean Medicine for colorectal cancer. Conclusions : Further objective and systemic clinical studies related to Korean Medicine are needed to develop more advanced clinical practice guidelines of colorectal cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5633-5636
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• 2012

Purpose: Breast cancer is an important cause of cancer-related death in women. Numerous studies have evaluated the association between the insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene and breast cancer risk. However, the specific association is still controversial rather than conclusive. Therefore, we performed a meta-analysis of related studies to address this controversy. Methods: PubMed, EMBASE, Google Scholar and the Chinese National Knowledge Infrastructure databases were systematically searched to identify relevant studies. A meta-analysis was performed to examine the association between the I/D polymorphism in the ACE gene and susceptibility to breast cancer. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated. Results: 10 separate studies of 7 included articles with 10,888 subjects on the relation between the I/D polymorphism in the ACE gene and breast cancer were analyzed by meta-analysis, and our results showed no association between the I/D polymorphism in the ACE gene and breast cancer in total population and different populations. No publication bias was found in the present study. Conclusions: The ACE I/D polymorphism may not be associated with breast cancer risk. Further large and well-designed studies are needed to confirm this conclusion.

• Asian Pacific Journal of Cancer Prevention
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• 제15권11호
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• pp.4467-4474
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• 2014

Background: We aimed to comprehensively review the evidence for using sputum DNA to detect non-small cell lung cancer (NSCLC). Materials and Methods: We searched PubMed, Science Direct, Web of Science, Chinese Biological Medicine (CBM), Chinese National Knowledge Infrastructure (CNKI), Wanfang, Vip Databases and Google Scholar from 2003 to 2013. The meta-analysis was carried out using a random-effect model with sensitivity, specificity, diagnostic odd ratios (DOR), summary receiver operating characteristic curves (ROC curves), area under the curve (AUC), and 95% confidence intervals (CI) as effect measurements. Results: There were twenty-two studies meeting the inclusion criteria for the meta-analysis. Combined sensitivity and specificity were 0.62 (95%CI: 0.59-0.65) and 0.73 (95%CI: 0.70-0.75), respectively. The DOR was 10.3 (95%CI: 5.88-18.1) and the AUC was 0.78. Conclusions: The overall accuracy of the test was currently not strong enough for the detection of NSCLC for clinical application. Dscovery and evaluation of additional biomarkers with improved sensitivity and specificity from studies rated high quality deserve further attention.

• 유통과학연구
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• 제16권11호
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• pp.11-19
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• 2018

Purpose - The purpose of this study is to provide a systematic literature review related to environmental upgrading in Global Value Chains (GVCs) and suggest possible future research agendas in advancing environmental upgrading and ultimately GVC boundaries. Research design, data, and methodology - The academic databases such as Science Direct, EBSCO, ProQuest and Google Scholar were explored using a structured keywords searches to identify relevant research in the environmental upgrading area in GVCs. Only relevant papers were selected after reading the abstracts, and analyzed using qualitative content analysis. Results - Overall analysis of the literature review suggests two critical developments in the field of environmental upgrading. The first and foremost major development is an enhanced understanding of environmental upgrading as a concept and phenomenon. The second significant development is that environmental upgrading has been empirically proven to be fundamentally based on relationships and power structures within GVCs. Conclusions - Environmental upgrading in GVCs has been studied individually and not in relation to financial outcomes and social upgrading. Hence, the relationship of environmental upgrading with financial outcomes and social upgrading needs to be investigated. Furthermore, the impact of the interaction of varying institutional structures on environmental upgrading is worthy of future study.

• 한국보건간호학회지
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• 제32권1호
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• pp.5-18
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• 2018

Purpose: We present improvements to the Korean home visiting healthcare service based on analysis of Korean home visiting healthcare services considering recent sociodemographic changes and demands for healthcare services. Methods: This is a review study in which the results are derived through a literature review and data analysis. We collected data through a search of electronic databases, Google Scholar, and governmental websites. Results: Changes in Korean home visiting healthcare services are classified into four stages: 'introduction (1990-2000)', 'pilot project (2003-2006)', 'nationwide expansion (2007-2012)', 'various types (2013-2018)'. Korean home visiting healthcare service based on public health centers has achieved outcomes such as improved health behavior and health management, increased health management ability, and establishment of comprehensive healthcare infrastructure. Conclusion: In the future, the demand for home visiting healthcare service will increase steadily because of deepening social polarization, rapid aging of the population, and increases in chronic diseases. To improve health management and health equity, we suggest that Korean home visiting healthcare service will expand to all the people as a core public health service. It is necessary to establish a management team for various types of home visiting healthcare service in the public health center.