• 대한후두음성언어의학회지
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• 제19권1호
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• pp.7-10
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• 2008

The early glottic cancers are traditionally treated by radiotherapy or endoscopic surgery. The excellent effectiveness of both treatment modalities for local control, larynx preservation, and disease specific death is similar. Therefore, functional voice outcome after treatment is one of the most important factors in the choice of treatment for early glottic cancer. To assess the functional outcomes and compare the voice quality in patients with early glottic cancer treated with curative intent with radiotherapy or laser cordectomy, we performed literature review. Most studies showed that the voice quality after radiation therapy is slightly better than that after laser cordectomy. Subanalysis according to types of laser cordectomy, however, indicates that voice quality depends on type of laser cordectomy. Especially, type I or type II laser cordectomy might be superior to other types of laser cordectomy and radiation therapy. We conclude that the laser cordectomy is a good surgical alternative for properly selected early glottic cancer including professional voice users.

• Journal of Trauma and Injury
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• 제29권2호
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• pp.37-42
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• 2016

Purpose: Arterial injury in children is a challenging problem for its special characteristics. It is rare even during warfare. This review described a personal experience in the management and outcome of acute pediatric arterial injuries of extremities. Methods: Thirty-six children below age of 13 years were studied during period from 2004 through 2014 in Iraq. Results: Male patients were 27 (75%) and female were 9 (25%). Seven to twelve years old was the most affected age group. The incidence of iatrogenic injuries was greater in infants and toddlers while penetrating injuries were the most common in older children. Upper limbs arteries were affected in 17 (47.2%) and lower limb in 19 (52.8%) patients. Hard signs were the commonest mode of presentation (83.3%). Lateral wall tear and complete transection were the most frequent types of arterial injury (36.1% and 27.8% respectively). The most frequent procedures performed were end-to-end anastomosis and lateral arteriorrhaphy. Surgical outcome was good. In 27 cases distal pulsations were regained. Seven cases had impalpable distal pulses but still viable limbs. Limb length discrepancy was detected in one case. One case was complicated with limb loss. No death was recorded. Conclusion: Arterial injuries in children are age related. The proper treatment of arterial injuries in children requires high index of suspicion, early operative intervention and continuous postoperative follow-up throughout years of active growth. Angiogram has a limited role as a diagnostic tool in acute arterial injuries.

• 한국동물위생학회지
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• 제37권3호
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• pp.203-212
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• 2014

Frog culture industry is not yet familiar but has much potential. Generally, in farm, the population density is higher than that of in nature and frog farm is not the exception. But when population density is high, it can easily leads to stressful condition, poor sanitation. When a disease occur, it is a primary factor that makes the population more susceptible and the results more grave. Because of severe Rhabditoidea- helminth infection and subsequent bacterial septicemia, 50~70% of the total population had been died in a farm in Jeong-sun in Gangwon-do and Chungju in Chungcheongbuk-do from late June, 2012 to September, 2012. Diseased frogs showed ruptured lung, bloody ascites, liver discoloration, myocardium weakness, congested kidney, microcytic anemia and so on. Enterobacteriacea, Citrobacter.sp, Cupriavidus metallidurans, Acinetobacter.sp were isolated as major bacterium that had caused septicemia in frogs. Among isolated bacterium, Cupriavidus metallidurans, Ewingella americana, Shewanella aquimarina and Pseudoalteromonas sp. have not reported as potential pathogens in frogs before. It is a good example that severe helminth infection in frogs can lead to secondary infection of bacteria.

• Archives of Pharmacal Research
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• 제27권5호
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• pp.495-501
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• 2004

A series of N-substituted-1,3-isoindolinedione derivatives (2-16) were synthesized for the purpose of defining the effect of N-substitution on the anticonvulsant activity of these derivatives. The target compounds (2-16) were obtained by condensation of phthalic anhydride with the corresponding amine derivative. The structures of the synthesized derivatives (2-16) were confirmed by means of IR, $^1$H-NMR, $^{13}$ C-NMR, MS and elemental analyses. The anticonvulsant activity of all compounds (2-16) were evaluated by subcutaneous pentylenetetrazole seizure threshold test at doses of 0.2, 0.4 and 0.8 mmol/kg compared with sodium valproate as a positive control. Their neurotoxicity were determined by the rotorod test. Many of the present series of compounds showed good anticonvulsant activity at the tested doses, as compared to sodium valproate. Three of them (4, 6 and 11) exhibited 100 % protection against convulsions, neurotoxicity and death at all tested doses. Out of the series, two compounds (12 and 13) were completely inactive with 100% mortality. 3-(p-chlorophenyl)-4-(1 ,3-dioxo-2,3-dihydro-1 H-2-isoindolyl) butanoic acid derivative (11) has emerged as the most active compound which is 20 times more active than valproate with ED$_{50}$ 8.7, 169 mg/kg; TD$_{50}$ 413, 406 mg/kg and PI 47.5, 2.4. The results revealed the importance of the combination of baclofenic and phthalimide moieties (compound 11) as a promising anticonvulsant candidate.

• 건축역사연구
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• 제8권1호
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• pp.63-80
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• 1999

Poet, Yi-sang, born in 1910, originally studied architecture in Kyeong Sung High Technical School. He also experienced an architectural practice in Chosun Chongdokbu (the Government office of Japanese empire in Korea) during 4 years. After resigned the post of architectural engineer in 1933, he became a man of letters. Until his death in 1937, he published the writings hard to understand, which remind us of the works of western avant-garde. Because of the peculiarity and difficulty of his poem and novels, he becomes the object of studies by many critics and historians of literature. And he is estimated as the representative of Korean modernism. This study tries to related Yi-sang's early poems to architectural discourse for the search of 'modernity' of Korean modern architecture. His early poems, which is published in from 1931 to 1933, are worthy of notice because they contained a acute shock derived from radically changed spacial structure, the absolute emptiness of the individual happened in the 1930's Seoul. They also show a different attitude from the writings of Park Dongjin and Park Kilryong, the architects contemporary with Yi-Sang. Compared with their writings, Yi sang's early poems had an insight into the totality of modern culture like western avant-gardes. Therefore Yi-sang's early poems can give us a good base to understand the characteristics of 'modernity' of Korean architecture.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제15권4호
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• pp.13-21
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• 2009

Healthcare design is always challenged to come up with the rapid changes in healthcare system and industry as well as complicated planning requirements. This thesis aims to grab good instructions from Louis I Kahn who designed more than 15 healthcare projects during his entire life, from the winning project of the student competition in 1920 to Ayub hospital in Dhaka, Bangladesh after his death. His many hospital projects are deeply related to his famous projects such as Yale Art gallery, Philips Exeter Library, and Sher-E-Bangla Nagar national capital of assembly hall. But, it is not easy to find the researches about his hospital projects among many books and theses about him. Thus, this thesis investigates them and their contextual and historical relationships in order to find the way to apply his knowledge and philosophy about healthcare design to the modern hospital projects. We expect that it will promote more following researches for his healthcare projects.

• 한국안전학회지
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• 제19권1호
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• pp.108-116
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• 2004

After the IMF financial crisis, a lot of risks in construction industry have been increased gradually with the expansion of construction industry widely, higher stories of building, and the expansion of the underground space and excavation work. These risks are bringing out construction accidents such as the death, the injury of worker and so on, not so much as it would be effected the corporation's image. In spite of these situations, many construction industries still maintain the wrong methods and not try to decrease construction accidents. Recently, we should focus on the fact that management system of the larger construction also is being good, on the other hand, the condition of the work in the case of smaller construction industries is very poor, construction company have a particular safety management system but it has a difference according to the construction magnitude, construction companies have a particular safety management system but it has a difference depending on the construction according to the construction magnitude. Therefore, this study will suggest the developed way of construction safety management by the comparison and analysis from the difference between the higher and the smaller construction industries.

• Journal of Chest Surgery
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• 제19권1호
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• pp.165-173
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• 1986

During the 4 year period from 1982 through 1985, twelve patients have undergone operations for discrete subaortic stenosis with good short-term clinical result at Department of Thoracic and cardiovascular Surgery, S.N.U.H. According to the cineangiographic and operative findings, nine of the 12 patients were classified as Deutsch type I, the other 3 as type II, and eleven of the 12 had one or more associated anomalies of the cardiovascular system such as PDA[5], VSD[5], left SVC[2], MS[1], COA[1], supramitral membrane[1], DORY[1], right aortic arch[1], DCRV[1], and TOF[1] [one with Shone`s complex], and three of them had secondary cardiac disorders such as aortic regurgitation[3],mitral regurgitation[2], and tunnel shaped dynamic obstruction of left ventricular outflow tract[2]. We have performed membrane resection via oblique aortotomy with retraction of the aortic cusps in 7 cases and via VSD from right cardiac chamber in 5 cases with large VSD and have also performed the operations on the correctable associated anomalies. There was only one operative death in patient with associated TOF due to neurologic complication and no other postoperative difficulties except in one patient with transient heart block resolved spontaneously on postoperative 3rd day. To our knowledge, this article is the first report of operation for discrete subaortic stenosis in Korean literature.

• Journal of Chest Surgery
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• 제22권5호
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• pp.739-747
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• 1989

Between September 1986, and August 1989, eight infants underwent operation for repair of coarctation of the aorta in the first year of life. The patients included 7 males and 1 female ranging in age 19 days and 9 months. Weights ranged from 3.5 Kg to 7 Kg [mean 5 Kg]. All patients had preductal coarctation of the aorta. Each infant had associated cardiac anomalies, including ventricular septal defect [7 infants] and patent ductus arteriosus [5 infants]. All had intractable congestive heart failure, despite aggressive medical therapy. Pressure gradient across the coarctation ranged from 10 mmHg to 60 mmHg. Operative techniques were subclavian flap aortoplasty in five cases, Gore-Tex patch aortoplasty in three cases. In addition to coarctation repair, six infants had concomitant banding of the pulmonary artery. Four infants required ventilator support for several days. There was no operative death. Complications developed in two. One infant had tracheal stenosis after a tracheostomy. Another infant had restenosis of the aorta revealed by cardiac catheterization 30 months after surgery. The pressure gradient was 30 mmHg, necessitating balloon dilatation aortoplasty. Results were satisfactory. During follow up, we performed total correction procedures [patch closure of the ventricular septal defect, infundibulectomy, pulmonary valvotomy and pulmonary artery angioplasty] in one case. Continuing follow-up finds all patients in good condition.

• 동의생리병리학회지
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• 제17권4호
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• pp.1120-1124
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• 2003

Erysipelas is a inflammatory disease that characterized by erythrism, heat sensation, swelling, pain and tenderness. In initial invasion chilling sense and hyperthermia occur suddenly and local skin turn into red like coating with paints. it spreads promptly and the boundary is manifest. the position of invasion is not settled and it recur over again. Compared with western medicine it is similar to the inflammation caused by group A p-hemolytic streptococcus. If a proper care for erysipelas is not done in the time of expiration. Inflammation diffuse on circumferential skin and Iymphnode due to the diffusion of pathogene. In serious case. it can lead to death by ichoremia. We have four healing cases using 'younkyopaedok-san' that obtain good results and report it.