• Bulletin of the Korean Chemical Society
• /
• 제31권7호
• /
• pp.1931-1936
• /
• 2010

Discovery and isolation of compounds capable of blocking the interactions between VCAM-1 and VLA-4, a major pair of adhesion molecules contributing to the different steps of leukocyte migration across the endothelium in inflammatory responses, has been a major goal of this lab. Through bioactivity-guided fractionation, five saikosaponins were subsequently isolated from the methanol extracts of the roots of Bupleurum falcatum L. Their structures were elucidated by spectroscopic analysis ($^1H-$, $^{13}C$-NMR and 2D-NMR), as follows, saikosaponins: A (1); D (2); C (3); B3 (4); B4 (5). Compounds 1 and 2 inhibited interaction of sVCAM-1 and VLA-4 of THP-1 cells with respective $IC_{50}$ values of 7.8 and 1.7 ${\mu}M$. The aglycone structure of 2 also showed cell adhesion inhibitory activity with an $IC_{50}$ value of 21.1 ${\mu}M$. With these results, we suspect these two saikosaponins from the Bupleurum falcatum L. roots to be prime candidates for therapeutic strategies towards inflammation.

• Journal of the Korean Dietetic Association
• /
• 제8권1호
• /
• pp.33-41
• /
• 2002

This study has been focused on understandings for the problems of dietitian who perform nutrition service in the field of industry foodservice and then focused on using of its findings as basic material for smooth nutrition service performance through analyzing job satisfaction, job characteristic and its importance of dietitians' task in industry foodservice. A questionnaire survey of 120 nutritionists who have engaged themselves in industry foodservice―60 are under direct management and 60, held in trust―has been performed, and 95 responses (79%) have been collected and categorized, except some unfinished responses. The examined data have been classified statistically by using of SPSS, and then analyzed into frequency, percentage, mean value, standard deviation, and correlation among factors, according to questionnaires. The findings of the research can be summarized as following: The details of the surveyed dietitians were: 20-25 years old on an average; working less than two years; college graduates; mere employees; receiving monthly pay of 70～100 won on an average; working more than 52 hours weekly; and providing with four meals a day in a single menu. For job satisfaction and job characteristic, the service itself and the understanding of the service appear as main features. For the relative importance of the service, the findings show that the menu making, sanitation and cost control occupy an important position, while nutrition counseling, nutrition education and dietary control by ailments make up very low portion. For the cause of not enacting the nutrition service, the lack of counseling ability and the overburden of food service are at the top. The findings of this research, therefore, present the needs of the service capacity education and the reduction of excessive foodservice hours of dietitians in order to secure the efficient nutrition service in industry foodservice. To achieve this goal, first of all, there should be an intensive education course in school by using of practice hours. for enhancing practical service adaptability, and then the computerization of foodservice should be executed perfectly to reduce the excessive foodservice hours.

• Journal of the Korean Society of Environmental Restoration Technology
• /
• 제20권3호
• /
• pp.19-31
• /
• 2017

Plants are the basis for sustainable green growth, and the value of existence and importance of trees including landscape Plants can't be emphasized enough. Therefore, they are precious living things thriving in all sorts of public services, and continuous civil complaints for justifiable compensation of landscape Plants are filed. First, the standard formula of planting intervals according to production target specifications is calculated using root-collar caliper and diameter at breast height, and apply (1) standard medium sized trees which have not yet reached commercialization [deciduous tree production goal (R(B) less than 6cm]= (target standard)= [target standard $R(cm){\times}15{\times}0.7$]. (2) In case of commercialization(R6~R10)= [target standard $R(cm){\times}15{\pm}5%$], (3) In case of more than R12= [target standard $R(cm){\times}15{\times}130%$] shall be applied. In case of using diameter at breast height (4) In case of commercialization(B6~B10)= [target standard $B(cm){\times}20{\times}15{\pm}5%$], (5) In case of more than B12= [target standard $B(cm){\times}20{\times}130%$] shall be applied. Second, appraisal methods based on tree classification of compensation for loss are classified according to planted locations. (1) landscape trees within a house=[price of arrival at the site+planting cost], (2) landscape trees in places such as arboretum=[management technology of tress + relocation expenses considering scarcity of the trees (3) landscape trees in a place of loads= [landscape tree production cost + work out added price. In case of producted landscape threes (4) landscape trees ready to be commercialized as sales loss.

• Journal of Families and Better Life
• /
• 제26권6호
• /
• pp.209-225
• /
• 2008

This study has been designed to develop integrated supportive service works for the families of disabled children registered in the D-Healthy Family Support Center. The service works are intended to improve family members' health and their growth potentials, and cover service programs of family education, counselling, culture solidarity, and information networks. There are two topics covered in this study; first, this study is to develop integrated supportive service programs for the families of disabled children, and second, the study is also to construct comprehensive strategies and plans for effective services after evaluating practical service programs. In this study, 31 families with one or more disabled children have been selected through stratified random sampling, and all the family members were observed for program effects of integrated service items developed from previously validated indices. For analysis, eight question items were made for interview and each item denotes satisfaction score ranging from 1(very dissatisfied) to 5(very satisfied) on the Likert's five point scale. Mean value of each item was counted after the program, and satisfaction scores were compared over the programs implementation. Overall, the satisfaction scores range 4.1 to 4.6, indicating relatively high satisfaction over most service program. Therefore, it is finally proposed that a longitudinal strategy model offer high quality service programs consistently for the target families, as a goal of achieving comprehensive cooperation and support exchanges between community and healthy family support center be schematized.

• Journal of Korea Society of Digital Industry and Information Management
• /
• 제6권3호
• /
• pp.159-168
• /
• 2010

Developments and changes in digital environment based on computer technologies and internet networks enabled us interactive communication for planning and execution through the freedom of 'connection', 'sharing', and 'conversion'. The subject of this study, interactive commercial, might be the core of success based on creation which stems from communication design, revolution in design and technology, and conversion. Communication in modern economy is not optional, but essential. Furthermore, like evolution process up to Augmented Reality from developments of mobile communication technology, or concept in paradigm change, digital interactive commercial means the core of success, not a part of it. Therefore, in order to achieve success in the global competition structure, mobile communication design, revolution, and creation which produce added value shall be working as a base. In order to reach effective communication process performance of interactive commercial media, this study would like to propose building a media commercial system which is realized by human senses. Using this, standardized methods for interactive commercial which can be used together with augmented reality based on digital technology, and for using digital robot contents are available, along with methodology system of their use. In addition, the ultimate goal of this study aims to discover new factors through reorganization of precedent analysis and adaptation based on academic achievement and practical application. And thus, it wants to contribute to practical use of interactive commercial out of augmented reality-based communication in which technology, marketing, and design are integrated to be used in real sense.

• 한국신재생에너지학회:학술대회논문집
• /
• 한국신재생에너지학회 2005년도 춘계학술대회
• /
• pp.416-421
• /
• 2005

Most of solar system dissemination has been focused on domestic hot water system of which utilization to a building is relatively simple and safe than solar heating system. Through the survey on a cause of solar house dissemination failure in Korea, we conclude that design integration and systematic approach method for technology application are the most important element for a successful solar house. KIER(Korea Institute of Energy Research) and Hanbat National University have started new project on a development of Zero energy Solar House, called ZeSH which can be sustained just by natural energy without the support of existing fossil fuel. This is the 1st phase research of 10 years long-term ZeSH plan which develops a low-cost and $100\%$ self sufficient ZeSH. The goal of 1st phase ZeSH research is to get a $70\%$ self sufficiency only in thermal loads. Actual demonstration house, named KIER ZeSH I was designed and constructed as a result of 1st phase research work in the end of 2002. Various innovative technologies such as super insulation, high performance window, passive and active solar systems, ventilation heat recovery system are applied and evaluated to the KIER ZeSH I. A lot of computer simulations had been conducted for the optimal design and system integration in every design steps. Considering all the results from detailed hourly computer simulation, it is expected that at least $70\%$ self-sufficiency in thermal loads which is 1st phase target value can be excessively achieved in actual demonstration house. Besides, many valuable findings from the design and analysis to construction could be established such as collaboration method among the participants, practical design and construction techniques for system integration and the others. The purpose of this paper is to introduce the main findings through the development of KIER ZeSH I project. Practical guidelines in every design step for new low- or zero- energy solar house is proposed as result.

• Journal of Korean Neurosurgical Society
• /
• 제52권4호
• /
• pp.365-371
• /
• 2012

Objective : To document lumbar lordosis (LL) of the spine and its change during surgeries with the different height but the same angle setting of the anterior cage. Additionally, we attempted to determine if sufficient LL is achieved at different cage heights and to quantify the change in LL during multi-level anterior lumbar interbody fusion (ALIF). Methods : The medical records and radiographs of 42 patients who underwent more than 2 level ALIFs between 2008 and 2009 were retrospectively reviewed. We evaluated 3 parameters seen on lateral whole spine radiographs : LL, pelvic incidence (PI), and sagittal vertical axis (SVA). The mean follow-up time was 28.1 months and the final follow-up radiographs of all patients were reviewed at least 2 years after surgery. Statistical analysis was performed using the paired t-tests. Results : Lumbar lordosis had changed up to 30 degrees immediately and 2 years after surgery (preoperative mean LL, SVA : 22.45 degrees, 112.31 mm; immediate postoperative mean LL, SVA : 54.45 degrees, 37.36 mm; final follow-up mean LL, SVA : 49.56 degrees, 26.95 mm). Our goal of LL is to obtain as much PI as possible, preoperative mean PI value was $55.38{\pm}3.35$. The pre-operative and two year post-surgery follow-up mean of the Japanese Orthopedic Association score were $9.2{\pm}0.6$ and $13.2{\pm}0.6$ (favorable outcome rate : 95%), respectively. In addition, we were able to obtain good clinical outcomes and sagittal balance with a subsidence rate of 22.7%. Conclusion : We were able to achieve sufficient LL, such that it was similar to the PI, utilizing multi-level ALIF with the use of a tall cage with the same angle setting of the cage. We have found out that achieving sufficient lumbar lordosis and sagittal balance require an anterior lumbar cage with high angle and height.

• Journal of the Korean Society of Clothing and Textiles
• /
• 제40권5호
• /
• pp.788-800
• /
• 2016

This study proposes an execution protocol for fashion therapy. Research on fashion therapy are limited and insufficient for the current need for the establishment of a fashion therapy theory. This study introduces cognitive behavior therapy, embodied cognition, and object relations theory as theories that underlie fashion therapy. A fashion therapy system model is provided based on the analysis of art therapy to explore its applicability to fashion therapy. The fashion therapy system model utilizes fashion items to managing pain and stress to better competence, encouragement and self-expression mechanisms to improve social, psychological, emotional and behavioral functions. In addition, 8 phases of the fashion therapy process (inquiry, forming rapport, assessment, goal-objective, observation, selection of strategy and design, practice, and the final evaluation and closing of fashion therapy) are suggested for developing a practical fashion therapy program. This study is to help overcome a negative perspective on fashion that provokes an excessive spending behavior and to make a practical contribution by creating more social value through fashion. The significance of the study is in the attempt to create an interdisciplinary approach of psychotherapy and fashion that can be extend into the fashion and textile discipline.

• Archives of design research
• /
• 제18권2호
• /
• pp.211-218
• /
• 2005

As digital Information equipment is new arrival, new paradigm such as 'function exist but form don't' is needed in the field of design. Therefore, the activity of design is focused on the relationship of human and machine against visual form. For that reason, it is involved emotional factor in the relationship and studied on new field, the emotional interlace. The goal of this paper is to suggest the way of emotional interface on searching multimedia data. The main target of paper is effect sound and human's step and the main way of research is visualization after measuring and analyzing numerically similarity level among emotion-words. This paper suggests the theoretical bad(ground such as personal opinion, the character of auditory information and human's step and case studies on the emotion research. The experimental content about sound is fueled from my previous research and the main experimental content about human's step is made with regression-expression to substitute Quantification method 1 for value about stimulation. The realistic prototype to apply the research result will is suggested on the next research after studying the search environment.

• The Journal of the Korea Contents Association
• /
• 제13권3호
• /
• pp.370-380
• /
• 2013

The research is basically designed to reveal a revisiting behavior for Chung Nam Dae which is inherently characterized sightseeing site. Distributional lag model is tentatively employed to analyze economic factors such as entrance fee and a different level of income. Empirical findings investigate that the revisiting behavior that is associated with a long run effect is more closely connected to the level of national income, but not the level of incomes in Chung Cheong region and Chung Buk province as well. As far as revisiting intention concerns, the entrance fee tends to affect to it by a shorter distributional lag, but the level of income affects to it by way of a pretty much longer distributional lags. To this end, perceived value for Chung Nam Dae should be exposed in order to induce a re-visitor. Such a goal could be attainable by taking care of its system for entrance fee, expanding facilities, re-branding, service improvement, and developing useful programs. Also, setting up an inter-connected networking system with a sightseeing site around is highly recommended.