• Journal of Life Science
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• v.19 no.1
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• pp.21-33
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• 2009

In this study, we investigated the effect of Rhei Rhizoma (RR; 大黃) water extract on gene expression in a hypoxia model of cultured rat hippocampal neurons. RR water extract $(2.5{\mu}g/ml)$ was added to the culture media on day 10 in vitro (DIV10), and a hypoxic shock (2% $O_2$/5% $CO_2$, $37^{\circ}C$, 3 h) was given on DIV13. After maintaining the cultures in normoxia for 24 hr, total RNA was isolated and used for microarray analysis. The MA-plot indicated that most genes were up- or downregulated within 2-fold. There were more downregulated genes (725 ea) than upregulated ones (472 ea) when larger than Global M value 0.2 (i.e., >15% increase) or smaller than Global M value -0.2 (i.e., >15% decrease) were considered. Antiapoptosis genes such as Tegt (2.4-fold), Nfkb1 (2.4-fold) Veg (1.8-fold), Ngfr (1.6-fold) were upregulated, while pro-apoptosis genes such as Bad (-64%), Cstb (-66%) were downregulated. Genes for combating environmental stress (stress response genes) such as Defb3 (2.7-fold), Cygb (2.2-fold), Ahsg (2.18-fold), Alox5 (2-fold) were upregulated. Genes for cell proliferation (cell cycle-related genes) such as Erbb2 (1.84-fold), Mapk12 gene (1.8-fold) was upregulated. Therefore, RR water extracts upregulate many pro-survival genes while downregulating many pro-death genes. It is interpreted that these genes, in combination with other regulated genes, can promote neuronal survival in a stress such as hypoxia.

• Korean Journal of Agricultural and Forest Meteorology
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• v.8 no.2
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• pp.86-96
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• 2006

Ecoclimap-1, a new complete surface parameter global database at a 1-km resolution, was previously presented. It is intended to be used to initialize the soil-vegetation- atmosphere transfer schemes in meteorological and climate models. Surface parameters in the Ecoclimap-1 database are provided in the form of a per-class value by an ecoclimatic base map from a simple merging of land cover and climate maps. The principal objective of this ecoclimatic map is to consider intra-class variability of life cycle that the usual land cover map cannot describe. Although the ecoclimatic map considering land cover and climate is used, the intra-class variability was still too high inside some classes. In this study, a new strategy is defined; the idea is to use the information contained in S10 NDVI SPOT/VEGETATION profiles to split a land cover into more homogeneous sub-classes. This utilizes an intra-class unsupervised sub-clustering methodology instead of simple merging. This study was performed to provide a new ecolimatic map over Northeast Asia in the framework of Ecoclimap-2 global database construction for surface parameters. We used the University of Maryland's 1km Global Land Cover Database (UMD) and a climate map to determine the initial number of clusters for intra-class sub-clustering. An unsupervised classification process using six years of NDVI profiles allows the discrimination of different behavior for each land cover class. We checked the spatial coherence of the classes and, if necessary, carried out an aggregation step of the clusters having a similar NDVI time series profile. From the mapping system, 29 ecosystems resulted for the study area. In terms of climate-related studies, this new ecosystem map may be useful as a base map to construct an Ecoclimap-2 database and to improve the surface climatology quality in the climate model.

• Korean Journal of Construction Engineering and Management
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• v.13 no.4
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• pp.78-88
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• 2012

As worldwide efforts to reduce global warming gases, the construction Industry is endeavoring to diminish carbon dioxides emissions. Especially, by introducing the LCA methodology to the industry, A variety of related studies to measure the emission of carbon dioxides have been conducted. However, when the conventional LCA methodology is applied to the construction projects, some limitations have been reported. To overcome the restrictions derived from the industry characteristics, this research suggested the Activity-based LCA model by applying the Activity-based Costing (ABC), which breaks down the whole life cycles into more detailed stages. By implementing the newly developed model, forecasting accuracy of $CO_2$ emission was elevated, and the critical control points on carbon dioxides were established. Through the case study of aluminium curtain-wall system, this research verified the usefulness of the Activity-based LCA.

• Journal of Korean Society on Water Environment
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• v.26 no.2
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• pp.268-278
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• 2010

This study derived the effectiveness analysis results of construction of wastewater treatment plant under climate change scenarios. Canadian Global Coupled Model (CGCM3) was used and A1B and A2 of Special Report on Emission Scenario (SRES) were selected. Regional climate change data for this application were downscaled by using Statistical Downscaling Model (SDSM) and the flow and BOD concentration durations were obtained by using Hydrological Simulation Program - Fortran (HSPF). The criteria for low flow and water quality were chosen as $Q_{99}$, $Q_{95}$, $Q_{90}$ and $C_{30}$, $C_{10}$, $C_1$. The numbers of days to satisfy the instreamflow requirements and target BOD concentration were also added to the criteria for comparison. As a results, small wastewater treatment plant improved the water cycle due to the increase of low flow and the decrease of BOD concentration. But climate change affected the reduction of effectiveness significantly. Especially in case of construction of small waste water treatment plant in the upstream region, it is necessary to take climate change impact into consideration since it is usually related to the low flow and the water quality of the stream.

• 한국신재생에너지학회:학술대회논문집
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• 2010.11a
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• pp.137.2-137.2
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• 2010

With current real economic growth of more than 10% per year, the Chinese energy consumption is rapidly increasing. Coal supply consists of the vast majority of China's total energy consumption requirements in 2008. China, the largest energy consumer, is expected to be heavily dependent on coal for future power generation, too (IEA,2009). A growing concern on global warming, on the other hand, drives Chinese government to declare her commitment to the reduction of CO2 emission by 2020. In this paper, China's energy market is examined for the current and future primary energy mix. Coal is found to be the biggest part accounting for 68.7% of total primary energy consumption while coal-fired power accounts for over 80% of the total power generation. The importance of Clean Coal Technology is being discussed based on the findings of the importance of coal in China's economy and its sustainable development. Among the technologies involved, a brief investigation of IGCC(Integrated Gasification Combined Cycle) technology with a review on current IGCC projects in China are provided from the perspective of environmental benefits. Studies on regional Chinese power market is also conducted. It is found that the regulated power tariff in electricity system makes the power suppliers suffer from financial loss and changes in the electricity price system is under serious consideration by Chinese government. Even though Chinese power market system causes difficulties of commercialization for IGCC technology, the potential benefits will be high due to China's huge requirements of power generating capacity and its heavy reliance on coal if the electricity price system can be changed smoothly.

• Journal of Digital Convergence
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• v.10 no.2
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• pp.47-53
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• 2012

Economic crisis, efforts to overcome the digital content industry development at home and abroad have been racing in the country's future lies in the digital content industry. Therefore, the digital content industry through vision, model identification knowledge-based global digital content market-based deployment is required. For research purposes the digital content industry to derive an alternative to national industrial development that will lay the groundwork. The deployment order for the first digital content industry, SWOT analysis performed to derive the Korean-specific model. As a result, measures based on the advancement of digital content industry as a long-term vision and specific goals are presented as staged. The age of convergence of the u-media content markets in government, corporations, consumers, and these form the structure of a virtuous cycle distribution systems for energy by being active, synergistic effects are obtained. Above all, based on the content industry to secure internal and external growth is key. Vision of the digital content, the growth momentum of the national social development policies to be used as a role model by changing the way a series of courses is required.

• Journal of Distribution Science
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• v.7 no.3
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• pp.101-122
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• 2009

This study examines internationalization determinant factors, motivation and goal of internalization, market entry methods, timing, region, internalization strategy and access method, internationalization performance and success factors, problems and troubles of internalization, and ultimately suggests internalization strategies for domestic venture companies. The study found that interior factors of internationalization determinant factors are characteristics of new firm and technological capabilities while exterior factors include narrow domestic market, industrialization level, competition level, product life cycle, economy of scale, and global network. Motivation was found to include securing and preoccupying market, cost reduction and efficient production through moving of production base, and the necessity of network formation.

• Journal of the Korean Geotechnical Society
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• v.35 no.12
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• pp.111-121
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• 2019

In the revised 2019 Guidelines for Facility Safety and Maintenance, the existing safety-oriented facility evaluations have expanded from performance evaluations to added durability and serviceability. This expansion reflects the life cycle of facilities and the service abilities of facilities, which are becoming a global issue. However, since the performance evaluation of facilities is linked to repairing and reinforcement, the related researches such as the correlation of each performance and the target performance related to the decision on priority are necessary. In this study, through the analysis of historical data of existing facility safety evaluation results centered on the retaining earth wall installed in domestic road facilities, the appropriate target performance was suggested for the maintenance of the facility based on the revised performance evaluation. Also, the performances on the actual two retaining walls were evaluated for example and analyzed the verification of the target performance. Besides, new indicators were presented to add serviceability to the performance evaluation of retaining earth walls consisting of safety and durability.

• Transactions of the Korean hydrogen and new energy society
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• v.26 no.6
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• pp.541-546
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• 2015

Global energy shortage problem is expected to increase driven by strong energy demand growth from developing countries. Nuclear fusion power offers the prospect of an almost infinite source of energy for future generations. Hydrogen isotope storage and delivery system is a important subsystem of a nuclear fusion fuel cycle. Metal hydride is a method of the high-density storage of hydrogen isotope. For the safety storage of hydrogen isotope, depleted uranium (DU) has been widely proposed. But DU needs a safe test because It is a radioactive substance. The authors studied a small-scale DU bed and a medium-scale DU bed for the safety test. And then we made a large-scale DU bed and stored hydrogen isotopes in the bed. Before the hydriding/dehydriding, we tested it's heating and cooling properties and carried out an activation procedure. As a result, Reaction rate of DU-$H_2$ is more rapid than the other metal hydride ZrCo. Through the successful storage result of our large bed, the development possibility of the hydrogen isotope storage technology seems promising.

• Journal of Korean Society of Forest Science
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• v.96 no.5
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• pp.503-509
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• 2007

The major objective of this study was to analyze the difference of the chemical characteristics of acid deposition in Quercus forests in Korea and Japan. The pH values of rainfall at the experimental forest of Kangwon National University (KS site) were higher than those at the Foresta Hills in Japan (JP site), and all chemical contents of throughfall and stemflow were much higher than those of rainfall in Quercus forest stands at the KS and JP site. The pH values, $Ca^{2+}$, $NO_3{^-}$ and $SO{_4}^{2-}$ concentration of throughfall and stemflow at the KS site showed seasonal variation. While at the JP site, the same pattern was shown in the pH values of throughfall and stemflow, however, did not show any difference among seasons. Also, the annual input of all nutrients in these two contrasting forests varied seasonally. These results can be used to predict the amounts of air pollutant that are washed off and leached by the rainfall and Yellow Sand (Asian dust), including NOx and SOx acid pollutants transported easterly from China in the spring. Therefore, it is necessary to quantify the inputs of dry and wet deposition throughout a full year to gain a more complete understanding of the effects of acid deposition on the nutrient cycles in these forest ecosystems.