• Journal of Korean Neurosurgical Society
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• v.58 no.6
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• pp.508-512
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• 2015

Background : Cerebral ischemia is as a result of insufficient cerebral blood flow for cerebral metabolic functions. Resveratrol is a natural phytoalexin that can be extracted from grape's skin and had potent role in treating the cerebral ischemia. Apoptosis, a genetically programmed cellular event which occurs after ischemia and leads to biochemical and morphological changes in cells. There are some useful markers for apoptosis like Bcl-2, bax, and p53. The last reports, researchers verify the apoptosis with early markers like Annexin V. Methods : We preferred in this experimental study a model of global cerebral infarction which was induced by bilateral common carotid artery occlusion method. Rats were randomly divided into 4 groups : sham, ischemia-reperfusion (I/R), I/R plus 20 mg/kg resveratrol and I/R plus 40 mg/kg resveratrol. Statistical analysis was performed using Sigmastat 3.5 ve IBM SPSS Statistics 20. We considered a result significant when p<0.001. Results : After administration of resveratrol, Bcl-2 and Annexin levels were significantly increased (p<0.001). Depending on the dose of resveratrol, Bcl2 levels increased, p53 levels decreased but Annexin V did not effected. P53 levels were significantly increased in ishemia group, so apoptosis is higher compared to other groups. Conclusion : In the acute period, Annexin V levels misleading us because the apoptotic cell counts could not reach a certain level. Therefore we should support our results with bcl-2 and p53.

• Journal of the Korea Society for Simulation
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• v.21 no.4
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• pp.35-46
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• 2012

As complexity of real-time systems is being increased ad hoc approaches to analysis of such systems would have limitations in completeness and coverability for states space search. Formal means using a model-based approach would solve such limitations. This paper proposes a model-based formal method for logical analysis, such as safety and liveness, of real-time systems at a discrete event system level. A discrete event model for real-time systems to be analyzed is specified by DEVS(Discrete Event Systems Specification) formalism, which specifies a discrete event system in hierarchical, modular manner. Analysis of such DEVS models is performed by Communicating DEVS (C-DEVS) formalism of a timed global state transition specification and an associated analysis algorithm. The C-DEVS formalism and an associated analysis algorithm guarantees that all possible states for a given system are visited in an analysis phase. A case study of a safety analysis for a rail road crossing system illustrates the effectiveness of the proposed method of the model-based approach.

• Journal of Global Scholars of Marketing Science
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• v.17 no.4
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• pp.223-245
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• 2007

Purpose: While empirical importance of dimensionality of perceived value is widely accepted, our understanding of experiential value dimensions in other retail channels and other cultures has not been explicitly tested. This study attempted to determine if the dimensions of experiential value scale (EVS) by Mathwick, Malhotra, and Rigdon (2001) identified in US catalog and Internet contexts could be applied in other international markets (South Korea) and in other retail channels (department store versus Internet shopping mall). Methodology/Approach: Two data sets, one from 220 department store shoppers and the other from 359 Internet shopping mall shoppers, were analyzed. Findings: Confirmatory factor analysis confirmed four different EVS dimensions by retail channels. Overall, entertainment and intrinsic enjoyment values were found to be more important in department store while economic and efficiency value dimensions were interpreted critical in Internet shopping mall context. Visual appeal aspect constitutes distinct value dimension in two channels. Practical Implications: One separate dimension of time efficiency in Internet shopping mall suggests that more efficient web design and functions that can save time and promote convenience are needed to better accommodate their customers. Internet has heavily relied on traditional attributes, such as factual information, price comparability, and brand name reliance. However, this study suggests that Internet shopping mall retailer should offer visual diversion and stimulation just as brick and mortar shopping malls do. Originality /Value of Paper: Although the research findings must be viewed as tentative because the results are from one country, they provide a rich basis for further understanding the dimensions of experiential value in other international markets and other retail channels. Category: Research Paper

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.4083-4088
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• 2016

Background: Physical inactivity has been identified as the fourth leading risk factor for global mortality and is associated with increased breast cancer diagnosis and recurrence. Purpose: To examine the association between adult lifetime physical activity and breast cancer risk in a case-control analysis. Materials and Methods: This study involved 122 cases of breast cancer and 121 controls in the state of Kelantan in Malaysia. A comprehensive measure of lifetime physical activity was used to assess occupational, household, and recreational/sports activity. For every type of activity, a metabolic equivalent (MET) score was assigned using the compendium of physical activities. MET-hours/week per year for all types of activities at different levels of intensities for different age groups were calculated. Logistic regression analysis was used to estimate odds ratios between various measures of physical activity and breast cancer risk. Conclusions: The mean MET-hours/week per year for all activities were 120.0 and 132.9 of MET-hours/week per year for cases and controls respectively. Household activities accounted for about 70% of the total lifetime physical activities. Only about 2.5% of the total lifetime physical activities were in the form of recreational/sports. This study found no association between lifetime occupational and recreational/sports physical activities with breast cancer risk among Kelantanese women. However, higher intensity lifetime household activities seemed to significantly reduce risk of breast cancer.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.26 no.4
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• pp.283-292
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• 2013

The objective of this research is to evaluate of global and local damage for steel-concrete composite structures under highway bridge exposed to fire loading. To enhance the accuracy and efficiency of the numerical analysis, the proposed transient nonlinear thermal structure interaction(TSI) parallel fire analysis method is implemented in ANSYS. To validate the TSI parallel fire analysis method, a comparison is made with the standard fire test results. The proposed TSI parallel fire analysis method is applied to fire damage analysis and performance evaluation for Buchen highway bridge. The result of analysis, temperature of low flange and web are exceed the critical temperature. The deflection and deformation state show good agreement with the fire accident of buchen highway bridge.

• Journal of the Korean Geographical Society
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• v.50 no.5
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• pp.557-569
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• 2015

This study aims to illustrate the national images of United Kingdom, France, and Germany based on the descriptions in the Korean middle school Social Studies textbooks in comparative perspective. In order to identify and compare the national images of the three countries, the author uses a framework for analysis consisting cognitive, normative, and relational factors. The main findings are as follows. First, the most frequently shown topics and issues are democratic institutions in the case of United Kingdom, respect for human rights in the case of France, and sustainable environment in the case of Germany. Second, for all the three countries, the most frequent factor among the three is cognitive one, followed by normative and then relational factors. Third, United Kingdom is described as a country of social unrest and conflict as well as a democratic country with long history and tradition. Fourth, France is described as a country of respect/abuse of human rights, potential for high tech industry, and largest agricultural state in Europe. Fifth, Germany is described more as a country of a leading country for global environmental protection than as a country with electronic and information technology.

• Preventive Nutrition and Food Science
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• v.6 no.1
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• pp.43-50
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• 2001

The effects of cardiac ischemia-reperfusion and $\beta$-adrenergic stimulation on metabolic function and energetics were investigated in Lan gendorff-perfused spontaneously hypertensive rat (SHR) hearts. Sarcoplasmic reticulum {TEX}$Ca^{2+}${/TEX}-dependent ATPase and cardiac lactate dehydrogenase (LDH) are additionally studied. The perfusion medium (1.0 mM {TEX}$Ca^{2+}${/TEX}) contained 5 mM glucose(+5 U/L insulin) and 2 mM pyruvate as substrates. Global ischemia was induced by reducing perfusion pressure of 100 to 40 cm {TEX}$H_{2}${/TEX}O, followed by 20 min reperfusin. Isoproterenol (ISO, 1$\mu$M) was infused for 10 min. Coronary vascular resistance and myocardial oxygen consumption ({TEX}$MVO_{2}${/TEX}) of SHR were increased in parallel with enhanced venous lactate during ischemia and reperfusion compared to those of Sprague Dawley (SD) hearts. Although ischemia-induced increase in venous lactate and combined adenosine plus inosine was abolished, coronary vasodilation produced in SD during reperfusion. In SHR, depressed reactive hyperemia was associated with a fall in cardiac ATP and CrP/Pi ratio and a rise in intracellular lactate/Pyruvate ratio. On the other hand, ISO produced coronary functional hyperemia and an increase in {TEX}$MVO_{2}${/TEX}. However, these responses were less than those in SHR hearts. The ATPase activity of SHR was attenuated in free {TEX}$Ca^{2+}${/TEX} concentrations used under basal condition and with ISO compared to that of SD. Venous lactate output and cardiac LDH activity were augmented in SHR as influenced by ISO. These results demonstrate that coronary reactive and functional hyperemia was dpressed in SHR, which cold be explained by alterations in the cytosolic phosphorylation potential and the cytosolic redox state manipulated by LDH, and by abnormal free calcium handling.

• Korean journal of communication and information
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• v.51
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• pp.136-155
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• 2010

Media diversity, coupled with the logic of competition in the global media market, has become a fashionable yet unfitting lingo of media policy in Korea. Media diversity has been fenced in the neoliberal economic logic of market competition and so tamed to consumers' free choice in the market. It is within this context that this article attempts to problematize narrowly-defined, market-oriented, and measurement-obssessed funtionalistic approaches to media diversity. In doing so, the article provides a critical overview of various definitions of media diversity. It also reveals how certain definitions, justifications, and measurements are legitimized and normalized in the name of science and objectivity. The core argument is that reflecting a larger neoliberal, deregulatory turn in media policy, media diversity has shifted from the pluralistic principle of democracy to the matter of free market choice or the myth thereof. It then focuses on the ongoing debate between state interventionists and free market liberals over the relationship between media ownership concentration and content diversity. Finally, it puts forth some recommendations as to how media diversity ought to be reconsidered as reformers' cultural politics, rather than marketeers' science, and discusses implications diversity has for deepening Korean democracy.

• Journal of Hydrogen and New Energy
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• v.19 no.6
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• pp.490-497
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• 2008

For continuous operation of the sulfur-iodine(SI) thermochemical cycle, which is expected practical method for massive hydrogen production, suggesting operation conditions at steady state is very important. Especially, in the Bunsen reaction section, the Bunsen reaction as well as side reactions is occurring simultaneously. Therefore, we studied on the relation between the variation of compositions in product solution and side reactions. The experiments for Bunsen reaction were carried out in the temperature range, from 268 to 353 K, and in the $I_2/H_2O$ molar ratio of $0.094{\sim}0.297$ under a continuous flow of $SO_2$ gas. As the result, sulfur formed predominantly with increasing temperature and decreasing $I_2/H_2O$ molar ratios. The molar ratios of $H_2O/H_2SO_4$ and $HI/H_2SO_4$ in global system were decreased as the more side reaction occurred. A side reactions did not appear at $I_2/H_2O$ molar ratios, saturated with $I_2$, irrespective of the temperature change. We concluded that it caused by the increasing stability of an $I_{2x}H^+$ complex and a steric hindrance with increasing $I_2/HI$ molar ratios.

• Journal of the Economic Geographical Society of Korea
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• v.23 no.3
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• pp.197-208
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• 2020

This study attempts to identify the structure of class conflict in Korea and to suggest an alternative framework for a empathetic society. The objective and subjective level of satisfaction with life and class consciousness are in direct proportion, and status consistency signifies polarization. Distorted distribution structures and cultural values make income disparity and property disputes widen, which in turn lead to educational divides and status fixations, refracting or blocking the possibility of social mobility. By overcoming the COVID-19 crisis, it is not appropriate to go back to the past but to correct wrong consciousness and practices in the past, and the consistency between the state and members of society must be re-established. Through the process of innovation at the economic, global, and digital level, a major transformation is required in the new normal era, which prioritizes social development for human values. The conflict resolution depends on the solidarity of the community as a social foundation, since an empathetic society needs the trust and communication of the members of the society.