• Title/Summary/Keyword: Global Minimum

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Lean Startup Application Study in the Healthcare Industrial point of View : The Case of Humedix Corporation (헬스케어산업 관점에서 본 린스타트업 적용 사례연구: (주)휴메딕스 사례를 중심으로)

  • Lim, Sung-Hoon;Kim, Yong-Tae
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.10 no.3
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    • pp.99-109
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    • 2015
  • The investment in healthcare industry has recently increased not only for global ventures but also for the domestic ventures. However, there has been hardship of founding and investment caused by healthcare startups characteristics that are costly and time consuming. In this study, the applicability of 'Lean Startup' theory to healthcare ventures was explored through the case of a domestic startup which accomplished funding from VC and KOSDAQ after establishing based on its technology in healthcare industry. There have been numerous case studies that applied 'Lean Startup' to IT industry. However, this case study that applied 'Lean Startup' to healthcare industry have some implications as follow: First, it is critical to conduct a hypothesis testing at initial research stage through R&D of 'MVP' (Minimum Viable Product) as the prototype testing is strictly prohibited in healthcare industry. Second, healthcare R&D teams ought to be well organized as startup teams and all researchers should be equipped with entrepreneurship as the licensing process in healthcare industry is time-consuming and costly due to issues like clinical studies. Lastly, management skills as smart and light as 'Lean Startup' are required in order to encourage young engineers' technology startups.

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Discrete Optimum Design of Sinusoidal Corrugated Web Girder (사인형 주름웨브보의 이산화 최적구조설계)

  • Shon, Su Deok;Yoo, Mi Na;Lee, Seung Jae
    • Journal of Korean Society of Steel Construction
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    • v.24 no.6
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    • pp.671-682
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    • 2012
  • The use of sinusoidal corrugated web girder for the box-type girders and gable steel main frames has recently been increasing very much. The reasons are that the thin web of the girder affords a significant weight reduction compared with rolled beam and welded built-up girder, and that corrugation prevents the buckling failure of the web. Improvements of the automatic fabrication process makes mass production of the corrugated web and unit possible, and applications of this girder have been extended considerably. Thus, the research for the optimum design processer considering the production data is needed practically. For doing this research, we develope the discrete optimum structural design program in consideration of production list data for the research, and the program apply to the single girder under the uniform load and the concentrated load as numerical example. We consider objective function as minimum weight of the girder, and use slenderness ratio, stress of flanges and corrugated web, and the girder deflection as the constraint functions. And also the Genetic Algorithms is adopted to search the global minimum point by using the production list as a discrete design variable. Finally, to verify the optimality of the design, we conduct a comparison of the results of the discrete optimum design with those of the continuous one, and also analyze the characteristics of the optimum cross-section.

Field Pullout Tests and Stability Evaluation of the Pretension Soil Nailing System (프리텐션 쏘일네일링 시스템의 현장인발시험 및 안정성 평가)

  • Kim, Hong-Taek;Choi, Young-Geun;Park, Si-Sam;Kim, Berm-Suk
    • Journal of the Korean GEO-environmental Society
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    • v.4 no.3
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    • pp.27-40
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    • 2003
  • In the present study, a newly modified soil nailing technology named as the PSN(Pretension Soil Nailing) system is proposed. Effects of various factors related to the design of the pretension soil nailing system, such as the length of a sheathing pipe and the fixed cone, are examined throughout a series of the displacement-controlled field pull-out tests. 9 displacement-controlled field pull-out tests are performed in the present study and the pretension forces are also evaluated based on the measurements. In addition, both short-term and long-term characteristics of pull-out deformations of the newly proposed PSN system are analyzed and compared with those of the general soil nailing system by carrying out the stress-controlled field pull-out tests. A numerical approach is further made to determine a postulated failure surface as well as a minimum safety factors of the proposed PSN system using the shear strength reduction technique and the $FLAC^{2D}$ program. Global minimum safety factors and local safety factors at various excavation stages computed in case of the PSN system are analyzed throughout comparisons with the results expected in case of the general soil nailing system. An efficiency of the PSN system is also dealt with by analyzing the wall-facing deformations and the adjacent ground surface settlements.

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Review of Minimum Curve Radius and Cant Range Setting for Mixed Section of Low and High speed Trains in Conventional Railway Line (일반철도의 저속 및 고속열차 혼용구간 최소곡선반경 및 설정캔트범위 검토)

  • Lee, Jae-Hyuk;Kim, Jeong-Hyeok;Park, Young-Gul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.10
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    • pp.345-353
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    • 2020
  • On conventional railway lines, trains with different speeds are operated. Therefore, trains moving on curved sections with cants must accept various ranges of balanced cants, cant deficiency, and cant excess, which is essential for the comfort and safety of train operation. In this study, the correlation between the curve radius, cant, and train speed on a track was analyzed to check the cant range that satisfies the criteria of train types, operation speed, cant deficiency, and cant excess. Also, the range of setting the cant by the curve radius and balanced cant were calculated by a regression analysis of train speed according to the frequency of operation in the case of mixed trains. The results could make it possible to improve the speed of the operation route, reduce the loss of ride quality, reduce the risk of derailing caused by cant deficiency, and minimize the load deflection by excess cant. This will ensure the safety of trains running on curves and improve the efficiency of track maintenance.

Numerical Study of Evaporation and Ignition of in-line Array Liquid Droplets (액적 배열의 증발과 착화에 관한 수치해석적 연구)

  • 김충익;송기훈
    • Fire Science and Engineering
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    • v.13 no.1
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    • pp.37-47
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    • 1999
  • The spreading fire of very small floating particles after they are ignited is fast and t therefore dangerous. The research on this area has been limited to experiments and global simulations which treat them as dusts or gaseous fuel with certain concentration well m mixed with air. This research attempted micro-scale analysis of ignition of those particles modeling them as liquid droplets. For the beginning, the in-line array of fuel droplets is modeled by two-dimensional, unsteady conservation equations for mass, momentum, energy and species transport in the gas phase and an unsteady energy equation in the liquid phase. They are solved numerically in a generalized non-orthogonal coordinate. The single step chemical reaction with reaction rate controlled by Arrhenius’ law is assumed to a assess chemical reaction numerically. The calculated results show the variation of temperature and the concentration profile with time during evaporation and ignition process. Surrounding oxygen starts to mix with evaporating fuel vapor from the droplet. When the ignition condition is met, the exothermic reactions of the premixed gas initiate a and burn intensely. The maximum temperature position gradually approaches the droplet surface and maximum temperature increases rapidly following the ignition. The fuel and oxygen concentration distributions have minimum points near the peak temperature position. Therefore the moment of ignition seems to have a premixed-flame aspect. After this very short transient period minimum points are observed in the oxygen and fuel d distributions and the diffusion flame is established. The distance between droplets is an important parameter. Starting from far-away apart, when the distance between droplets decreases, the ignition-delay time decreases meaning faster ignition. When they are close and after the ignition, the maximum temperature moves away from the center line of the in-line array. It means that the oxygen at the center line is consumed rapidly and further supply is blocked by the flame. The study helped the understanding of the ignition of d droplet array and opened the possibility of further research.

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Design of Multimode Block Cryptosystem for Network Security (네트워크 보안을 위한 다중모드 블록암호시스템의 설계)

  • 서영호;박성호;최성수;정용진;김동욱
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.28 no.11C
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    • pp.1077-1087
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    • 2003
  • In this paper, we proposed an architecture of a cryptosystem with various operating modes for the network security and implemented in hardware using the ASIC library. For configuring a cryptosystem, the standard block ciphers such as AES, SEED and 3DES were included. And the implemented cryptosystem can encrypt and decrypt the data in real time through the wired/wireless network with the minimum latency time (minimum 64 clocks, maximum 256 clocks). It can support CTR mode which is widely used recently as well as the conventional block cipher modes such as ECB, CBC and OFB, and operates in the multi-bit mode (64, 128, 192, and 256 bits). The implemented hardware has the expansion possibility for the other algorithms according to the network security protocol such as IPsec and the included ciphering blocks can be operated simultaneously. The self-ciphering mode and various ciphering mode can be supported by the hardware sharing and the programmable data-path. The global operation is programmed by the serial communication port and the operation is decided by the control signals decoded from the instruction by the host. The designed hardware using VHDL was synthesized with Hynix 0.25$\mu\textrm{m}$ CMOS technology and it used the about 100,000 gates. Also we could assure the stable operation in the timing simulation over 100㎒ using NC-verilog.

New Regulatory Formulation Approaches for IMO Maritime Safety Regulations (국제해사기구 해사안전규정의 새로운 제정방향에 대한 연구)

  • Park, Joo sung;Ha, Weon jae
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.22 no.7
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    • pp.773-781
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    • 2016
  • The present SOLAS Convention has maintained safety regulations in a largely prescriptive form and this has become overly prescriptive now. The prescriptive rules do not properly reflect technical advances and changing environments in the maritime sector in a timely manner. The purpose of this study is to provide preliminary research to lay a foundation for the development of a new regulatory framework based on safety performance which is not a prescriptive rule making bases. This study reviewed the concept and characteristics of a minimum requirement, the implications of safety regulations in terms of strategic, commercial and technical aspects, the compensative correlation between constructional requirements and operational measures, the concept of safety with regard to final stage confirmation of functions, expansion of implementers and objects of safety regulations, and the balance between safety and environmental protection requirements. Based on these research, 10 principles for the rule formulation process has been suggested such as consideration on the hardware requirements and software requirement, the multi-stage approval concept, new safety concerns for complex shipboard systems, considerations on the human element, regulatory impact assessments and measures to reduce administrative burdens.

A Study on Virtual Source-based Differentiated Multicast Routing and Wavelength Assignment Algorithms in the Next Generation Optical Internet based on DWDM Technology (DWDM 기반 차세대 광 인터넷 망에서 VS기반의 차등화된 멀티캐스트 라우팅 및 파장할당 알고리즘 연구)

  • Kim, Sung-Un;Park, Seon-Yeong
    • Journal of Korea Multimedia Society
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    • v.14 no.5
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    • pp.658-668
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    • 2011
  • Over the past decade, the improvement of communications technologies and the rapid spread of www (World Wide Web) have brought on the exponential growth of users using Internet and real time multimedia multicast services like video conferencing, tele-immersive virtual reality, and Internet games. The dense-wavelength division multiplexing (DWDM) networks have been widely accepted as a promising approach to meet the ever-increasing bandwidth demands of Internet users, especially in next generation Internet backbone networks for nation-wide or global coverage. A major challenge in the next generation Internet backbone networks based on DWDM technologies is the resolution of the multicasting RWA (Routing and Wavelength Assignment) problem; given a set of wavelengths in the DWDM network, we set up light-paths by routing and assigning a wavelength for each connection so that the multicast connections are set-upped as many as possible. Finding such optimal multicast connections has been proven to be Non-deterministic Polynomial-time-complete. In this paper, we suggest a new heuristic multicast routing and wavelength assignment method for multicast sessions called DVS-PMIPMR (Differentiated Virtual Source-based Priority Minimum Interference Path Multicast Routing algorithm). We measured the performance of the proposed algorithm in terms of number of wavelength and wavelength channel. The simulation results demonstrate that DVS-PMIPMR algorithm is superior to previous multicast routing algorithms.

Comparison of the Seed Productivity of Italian Ryegrass in Different Regions (다른 지역에서 이탈리안 라이그라스의 종자 생산성 비교)

  • Byeon, Ji-Eun;Lee, Hong-Ju;Hwang, Sun-Goo;Ryoo, Jong-Won
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.4
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    • pp.428-434
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    • 2021
  • To study whether the area under the cultivation of Italian ryegrass (IRG) has increased with rise in global temperatures, we investigated the effects of climatic variables on seed productivity in different parts of Gangwon-do, South Korea. Specifically, IRG was cultivated in the western (Gangneung), central (Wonju), and northern (Chuncheon) parts of Gangwon-do. The heading date of IRG in Gangneung was earlier than that in the other regions. Moreover, the values of agronomic traits, including spikelets per spike, grains per spike, and thousand-grain weight, were lower in Chuncheon. However, there were no differences spikelets per spike and grains per spike between Wonju and Gangneung. Additionally, the thousand-grain weight and seed production were higher in Gangneung. Statistical correlation analysis between climatic variables and agronomic traits revealed that the mean daily minimum temperature was positively correlated with seed formation-related traits in April and seed maturity-related traits in May. In the light of rising minimum temperatures in Gangwon-do, Gangneung, Chuncheon and Wonju are suitable areas for IRG cultivation with optimal seed productivity.

Improvement in Regional-Scale Seasonal Prediction of Agro-Climatic Indices Based on Surface Air Temperature over the United States Using Empirical Quantile Mapping (경험적 분위사상법을 이용한 미국 지표 기온 기반 농업기후지수의 지역 규모 계절 예측성 개선)

  • Chan-Yeong, Song;Joong-Bae, Ahn;Kyung-Do, Lee
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.24 no.4
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    • pp.201-217
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    • 2022
  • The United States is one of the largest producers of major crops such as wheat, maize, and soybeans, and is a major exporter of these crops. Therefore, it is important to estimate the crop production of the country in advance based on reliable long- term weather forecast information for stable crops supply and demand in Korea. The purpose of this study is to improve the seasonal predictability of the agro-climatic indices over the United States by using regional-scale daily temperature. For long-term numerical weather prediction, a dynamical downscaling is performed using Weather Research and Forecasting (WRF) model, a regional climate model. As the initial and lateral boundary conditions of WRF, the global hourly prediction data obtained from the Pusan National University Coupled General Circulation Model (PNU CGCM) are used. The integration of WRF is performed for 22 years (2000-2021) for period from June to December of each year. The empirical quantile mapping, one of the bias correction methods, is applied to the timeseries of downscaled daily mean, minimum, and maximum temperature to correct the model biases. The uncorrected and corrected datasets are referred WRF_UC and WRF_C, respectively in this study. The daily minimum (maximum) temperature obtained from WRF_UC presents warm (cold) biases over most of the United States, which can be attributed to the underestimated the low (high) temperature range. The results show that WRF_C simulates closer to the observed temperature than WRF_UC, which lead to improve the long- term predictability of the temperature- based agro-climatic indices.