• Title/Summary/Keyword: Giseong

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Root Bark of Morus alba L. and Its Bioactive Ingredient, Ursolic Acid, Suppress the Proliferation of Multiple Myeloma Cells by Inhibiting Wnt/β-Catenin Pathway

  • Song, Geu Rim;Choi, Yoon Jung;Park, Soo Jin;Shin, Subeen;Lee, Giseong;Choi, Hui Ji;Lee, Do Yup;Song, Gyu-Yong;Oh, Sangtaek
    • Journal of Microbiology and Biotechnology
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    • v.31 no.11
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    • pp.1559-1567
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    • 2021
  • The root bark of Morus alba L. has cytotoxic activity against several types of cancer cells. However, little is known about its chemopreventive mechanisms and bioactive metabolites. In this study, we showed that M. alba L. root bark extracts (MRBE) suppressed β-catenin response transcription (CRT), which is aberrantly activated in various cancers, by promoting the degradation of β-catenin. In addition, MRBE repressed the expression of the β-catenin/T-cell factor (TCF)-dependent genes, c-myc and cyclin D1, thus inhibiting the proliferation of RPMI-8226 multiple myeloma (MM) cells. MRBE induced apoptosis in MM cells, as evidenced by the increase in the population of annexin VFITC-positive cells and caspase-3/7 activity. We identified ursolic acid in MRBE through LC/mass spectrum (MS) and observed that it also decreased intracellular β-catenin, c-myc, and cyclin D1 levels. Furthermore, it suppressed the proliferation of RPMI-8226 cells by stimulating cell cycle arrest and apoptosis. These findings suggest that MRBE and its active ingredient, ursolic acid, exert antiproliferative activity by promoting the degradation of β-catenin and may have significant chemopreventive potential against MM.

The Comparison of Activation Protocols for PEMFC MEA with PtCo/C Catalyst (PtCo/C 촉매를 사용한 PEMFC MEA의 활성화 프로토콜 비교)

  • GISEONG LEE;HYEON SEUNG JUNG;JINHO HYUN;CHANHO PAK
    • Journal of Hydrogen and New Energy
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    • v.34 no.2
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    • pp.178-186
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    • 2023
  • Three activation methods (constant voltage, current cycling, and hydrogen pumping) were applied to investigate the effects on the performance of the membrane electrode assembly (MEA) loaded with PtCo/C catalyst. The current cycling protocol took the shortest time to activate the MEA, while the performance after activation was the worst among the all activation methods. The constant voltage method took a moderate activation time and exhibited the best performance after activation. The hydrogen pumping protocol took the longest time to activate the MEA with moderate performance after activation. According to the distribution of relaxation time analysis, the improved performance after the activation mainly comes from the decrease of charge transfer resistance rather than the ionic resistance in the cathode catalyst layer, which suggests that the existence of water on the electrode is the key factor for activation.

Selection of Replantation Species in Roadside Cutting-slope Area of the Baekdu Range (백두대간 도로 절토비탈면의 녹화수종 선정)

  • Song, Hokyung;Jeon, Giseong;Kim, Namchoon;Park, Gwansoo;Kwon, Hyejin;Lee, Jihye
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.10 no.3
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    • pp.52-59
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    • 2007
  • This study was carried out to select proper species for early stage replantation in cutting-slope area of the Baekdu Range roadside. In the cutting-slope area and upper forest area of the cutting-slope area, sample plots of 46 were selected and their vegetations and environmental factors were investigated. We found total 90 species in the 46 plots. We found Festuca arundinacea in 27 plots of the 46 plots. We also found Lespedeza bicolor in 26 plots, Eragrostis curvula in 22 plots, Artemisia princeps var. orientalis in 19 plots, Erigeron annuus and Pinus densiflora in 15 plots, Lactuca indica var. laciniata in 14 plots, Miscanthus sinensis in 13 plots, Oenothera odorata, Commelina communis, and Humulus japonicus in 11 plots, Lespedeza cuneata in 10 plots, Salix koreensis and Salix hulteni in 9 plots, Festuca rubra, Youngia denticulata, Aster scaber, and Festuca arundinacea in 8 plots, Chenopodium album var. centrorubrum in 7 plots, Patrinia villosa and Erigeron canadensis in 6 plots, and Setaria viridis, Digitaria sanguinalis, and Dactylis glomerata in 5 plots.The dominancy of Festuca arundinacea, Eragrostis curvula, Lespedeza bicolor, Miscanthus sinensis, Pinus densiflora, Festuca arundinacea, Festuca rubra, Artemisia princeps var. orientalis, Erigeron annuus, Lespedeza cuneata, Dactylis glomerata, Salix koreensis, Alnus hirsuta, Pueraria thunbergiana, Medicago sativa, Lactuca indica var. laciniata, and Digitaria sanguinalis were 13.41% 11.87%, 4.88%, 4.56%, 3.38%, 2.29%, 2.14%, 2.14%, 1.99%, 1.95%, 1.54%, 1.47%, 1.44%, 1.37%, 1.15%, 1.13%, 1.07% in the roadside cutting-slope, respectively. The dominancy of Rhododendron mucronulatum, Lindera obtusiloba, Rhus trichocarpa, Quercus mongolica, Lespedeza bicolor, Rhododendron schlippenbachii, and Quercus serrata 22.15%, 13.36%, 13.14%, 12.03%, 11.74%, 11.20%, and 11.14% in shrub layer of the upper forest area, respectively. The species of Rhododendron mucronulatum, Lindera obtusiloba, Rhus trichocarpa, Rhododendron schlippenbachii, Zanthoxylum schinifolium, Weigela subsessilis, Stephanandra incisa, Rhamnus davurica, Ligustrum obtusifolium, Lindera erythrocarpa, Rosa multiflora, Rubus coreanus, Symplocos chinensis for. pilosa, Smilax china, Prunus sargentii, and Staphylea bumalda may be more helpful in stabilizing of the cutting-slope area and making harmony with the surrounding forest area.

Consumer Categorization Based on Perception of Functional Jacket and their Utilization of Functional Information and Hang-tag (기능성의류 인식에 따른 소비자 분류와 이에 따른 제품정보 및 행택 활용도 연구)

  • Bang, Giseong;Yoo, Shinjung
    • Science of Emotion and Sensibility
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    • v.18 no.4
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    • pp.75-86
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    • 2015
  • As a part of integrated study for technical communication between consumer and manufacturer of functional clothing, functional clothing consumers were categorized based on their perception of the functional outdoor jacket and the differences in the source of information and use of hang-tag were examined according to the groups. Questionnaire survey was conducted on 472 males and females in their 20s to 60s, who have experience of purchasing functional outdoor jackets. Perception of functional outdoor jackets was classified into four factors ('functionality', 'price', 'experience/knowledge' and 'brand/design') and the respondents were categorized into three groups according to the factors: 'unconversant/brand & design pursuing group', 'conversant/function pursuing group' and 'high-priced products preferring group'. 'Unconversant/brand & design pursuing group' was composed of high rate of office workers and students in their 20s and 30s who use internet most frequently as source of information while 'conversant/function pursuing group' was composed of high rate of professionals in their 40s and 50s who make the most frequent use of information on hang-tag. 'High-priced products preferring group', which has high rate of the elderly in their 60s and housewives, obtain their information mainly from salespersons. 'Unconversant/brand & design pursuing group' was satisfied with functional information more than other two groups and 'conversant/function pursuing group' concerned for the hang-tag and required more explanation of terminology used in hang-tag. The results effectively explained the features of consumer groups and their different responses toward the information of functional outdoor jacket.

A Study on Effectiveness of Hang-Tag Type and Preferred Method of Functional Information for Outdoor Jackets (아웃도어 재킷의 기능성표기 행택 유형에 대한 소비자의 이해도 및 선호도 연구)

  • Bang, Giseong;Yoo, Shinjung
    • Science of Emotion and Sensibility
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    • v.19 no.4
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    • pp.83-94
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    • 2016
  • The aim of this study was to investigate effective expression method of performance information of functional clothing and preferred alternatives for the categorized consumer groups according to the perception about the functional outdoor jacket. 472 males and females in their 20s-60s' were surveyed and their answers were analysed and categorized by using SPSS 21.0 statistical program. For the study, four different expression methods for waterproof & breathable fabric, 'illustration only', 'illustration+Korean text', 'illustration+foreign text', and 'chart with Korean text', were presented and asked for finding correct answers. The analysis was done for three categorized consumer groups from the former study, 'unconversant/brand & design pursuing group', 'conversant/function pursuing group' and 'high price/high function preferring group'. The results showed that regardless of groups, 'picture only' was the most preferred method and 'graph' was the least. However, the percentage of correct answers for the 'graph' was the biggest, especially for 'conversant/function pursuing group'. It implied that the effective expression method should be differentiated depending on the target consumer groups. 'Conversant/function pursuing group' more agreed on the need for additional information, such as 'after-washed performance', than other two groups.

Vegetation Structure and Succession of Highway Cutting-slope Area (고속도로 절토비탈면의 식생구조와 천이)

  • Song, Hokyung;Jeon, Giseong;Lee, Sanghwa;Kim, Namchoon;Park, Gwansoo;Lee, Byungjun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.8 no.6
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    • pp.69-79
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    • 2005
  • This study was carried out to select proper species for early stage replantation in highway cut-slope area. In highway cut-slope area, sample plots of 106 were selected, and their vegetations and environmental factors were investigated. 1. We found total 172 species in the 106 cutting area of highway. The species of high frequency of highway cut-slope were found in the order of Lespedeza bicolor, Artemisia princeps var. orientalis, Festuca arundinacea, Erigeron annuus, Lespedeza cuneata, Lactuca indica var. laciniata, Eragrostis curvula, Dactylis glomerata, Oenothera lamarckiana, Wistaria floribunda, Humulus japonica, Commelina communis, Miscanthus sinensis, Pueraria thunbergiana, Pinus densiflora, etc. 2. The average vegetation coverage was over 90% in the study sites and the average coverage was 91.4% in the total cut-slope area. The species of high coverage of highway cut-slope area were found in the order of Festuca arundinacea, Eragrostis curvula, Lespedeza bicolor, Wistaria floribunda, Lespedeza cuneata, Dactylis glomerata, Artemisia princeps var. orientalis, Humulus japonica, Pueraria thunbergiana, Robinia pseudoacacia, Poa pratensis, Medicago sativa, Festuca ovina, Pinus densiflora, Parthenocissua tricuspidata, etc. 3. The total coverage in the foreign plants of Festuca arundinacea, Eragrostis curvula, Dactylis glomerata, Poa pratensis, Medicago sativa, Coreopsis drummondii and native plants of Lespedeza bicolor, Wistaria floribunda, Lespedeza cuneata, Amorpha fruticosa, Indigofera pseudotinctoria, Lespedeza cyrtobotrya were 57.52%. That is, the ecological succession of native herbs and parachute shrubs have delayed because the afforested plants occupy 57.52%. In future, the coverage of foreign herbs have to reduce, and the coverage of the native herbs and parachute shrubs must be increased. 4. The native seed of Artemisia sp., Miscanthus sinensis, Smilax china, Pueraria thunbergiana, Rubus crataegifolius, Rubus parvifolius, Pinus densiflora, Rhus chinensis, Albizzia julibrissin, Rhododendron mucronulatum, Clematis apiifolia, Zanthoxylum schinifolium, Prunus sargentii could be added in the seedling of the temperate south zone highway with the used seeds. The native seed of Artemisia sp., Miscanthus sinensis, Rubus crataegifolius, Rhododendron mucronulatum, Weigela subsessilis, Stephanandra incisa, Rhus chinensis, Pinus densiflora, Salix koreensis, Cocculus trilobus, Populus alba, Spiraea prunifolia for. simpliciflora, Clematis apiifolia, Lindera obtusiloba, Quercus serrata, etc., could be added in the seedling of the temperate middle zone highway with the used seeds. 5. We have some recommendation. The native plants have to growth in the highway cut-slope area instead of foreign plants to have good environmental ecology. The role of the foreign plants should be the plant for the initial several years in the highway cut-slope area. And, the native plants should growth in the next season. 6. We should protect shrubs and trees in the highway slope area because shrubs and trees can be more helpful in stabilizing of the slope area than herbs.

An Analytical Study on the Revegetation Methods for Highway Slopes (고속도로 절·성토 비탈면 녹화 공법의 적용 실태 연구)

  • Kim, Namchoon;Song, Hokyung;Park, Gwansoo;Jeon, Giseong;Lee, Sanghwa;Lee, Byungjoon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.10 no.2
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    • pp.1-15
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    • 2007
  • A variety of revegetation methods are being utilized and developed. However, most of revegetation methods used on highway slopes in Korea are based on foreign-introduced plant varieties to stabilize road surfaces and to administer afforestation for surface covering at an earlier phase. Therefore. it results in various problems. such as failure to achieve harmony with the surrounding vegetation and 10 cause re-denudation of slopes as the foreign-in introduced plant varieties wane out from 2~3 years after hydro-seeding, etc. In addition, some of the revegetation plants seeded in the earlier phase grow excessively high, thus causes successional problems, such as to inhibit the invasion of the secondary vegetation from the surrounding areas, etc. Therefore, in this study, 160 slopes located in the nationwide express highways have been investigated and analyzed in order to produce basic data for restoration of ecological environment in slopes created on a long-term basis by investigating and analyzing locational characteristics of cut and filled slopes in express highways, status of revegetation methods, characteristics of soil and plant-ecological environment. 1. Investigation on cut and embanked slopes in express highways was carried out in the total of 160 locations, which include 108 cut slopes and 52 embanked slopes. As a whole, the most frequently used revegetation method was seed spray, which was found to be used in the total of 55 target slops investigated. 2. Planting method of Wistaria floribunda applied to some of the blasted rock zones was found to cause damages as Wistaria floribunda trailed up the surrounding vegetation and the secondary invaded trees. In order to prevent this, this method must be used only in the lowest parts of large-sized slopes. Also, it will be required to administer continuous management and maintenance in the areas already planted with this plants. 3. The areas of blasted rock and ripping rock slopes were applied with coir net (net + seeding) method. However, many of these areas failed in achieving ground covering. Most areas where revegetation was in progress, they were covered with Eragrostis curvula(Weeping lovegrass) only. In areas with soil, such as decomposition of granite, where afforestation is difficult. In this slopes, soil base must be improved by hrdroseeding with thin-layer vegetation base application methods in order to achieve success in afforestation with native plants. 4. Woody species, rather than herb species, are more helpful in stabilization of slope surfaces. Therefore, it is important to be able to grow and protect woody species on highway slopes. Growth of woody vegetation is most largely influenced by soil depth. Thus, when hydro-seeding woody plants, it is recommended to apply at the upper layer of the slopes, which is capable to sufficiently provide the fundamentals required in plant growth.

The Value and Application of The Mt. Palgong in Daegu (대구 팔공산의 가치와 활용방안)

  • JEON, Young-Gweon
    • Journal of The Geomorphological Association of Korea
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    • v.19 no.2
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    • pp.51-68
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    • 2012
  • This paper aims to investigate the value in culture, history and ecology of the Mt. Palgong. It attempts to build the strategy for making use of The Mt. Palgong by literature survey, interview, and field survey. The main results are as follows: 1) The boundary of physical geography of the Mt. Palgong is classified into two. The boundary of the Mt. Palgong limits to granite mass block in a narrow sense, while in a broad sense, the boundary of the Mt. Palgong includes a contact aureole to be bordered on the Mt. Palgong granite mass block. The boundary from a cultural viewpoint limits to Daegu city(excluding Dalseong county) and Gyeongsan city, Yeongcheon city, Gunwi county and Chilgok (Dongmyeong-myeon, Giseong-myeon) in Gyeongbuk province. 2) In the geological boundary, one of the south-west slope is clearer than that of the north-east slope of the Mt. Palgong. The landforms such as tor, sheeting joint and gutter are well developed as a whole. Mountain landform such as boulder stream, polygonal cracking is relatively well developed on the south-west slope, while river landform is relatively well developed on the north-east slope of the Mt. Palgong. 3) It is necessary to develope various masterpiece of interesting stories related to Mt. Palgong in order to make the Mt. Palgong excellent tour complex. 4) It is desirable to designate the Mt. Palgong as a national park for systematic management. A master plan should be ultimately designed to raise brand value of Daegu city, and make good identity of the city by restoring 'The Mt. Palgong Jecheondan' and registering 'Gatbawi' as world heritage. 5) It is reasonable that the method of development in The Mt. Palgong should be based on the pattern of 'slow life town'. 'The Mt. Palgong museum' will then be designed to give visitors all the informations on The Mt. Palgong.

The Impact of Health Teachers' Behavioral Characteristics on Organizational Commitment: Ffocusing on Self-Efficacy and Task Importance (보건교사의 행동적 특성이 조직몰입에 미치는 영향: 자기효능감과 과업중요성을 중심으로)

  • Sangho Park;Kyung Kim;Shincheol Kang
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.19 no.4
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    • pp.215-229
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    • 2024
  • The purpose of this study was to explore various factors that affect the organizational commitment of health teachers' behavioral characteristics and explain the causal relationship between each factor. As an exploratory study, the subjects were about 500 people working as health teachers. A survey was conducted, and 190 responses were collected. Descriptive statistics were analyzed using SPSS, and the measurement model and hypotheses were tested using structural equation modeling. As a result of the analysis, the behavioral characteristics of health teachers were found to have a positive effect on their self-efficacy, and the behavioral characteristics and self-efficacy were found to have a positive effect on emotional commitment. In addition, health teachers' self-efficacy has a positive effect on emotional commitment, which means that rather than their behavioral characteristics having a direct effect on emotional commitment, their behavioral characteristics indirectly affect emotional commitment through a mediator called self-efficacy. It shows that it has an impact. In particular, it was confirmed that the school nurse's level of awareness of the importance of the task affected self-efficacy and emotional commitment. The implication of this study is that it explained the phenomenon of transfer of their behavioral characteristics to organizational commitment by empirically revealing that the competency, or behavioral characteristics, of health teachers are a factor affecting organizational commitment through self-efficacy. The goal is to empirically demonstrate that awareness of task importance, a job characteristic, affects self-efficacy and organizational commitment. The results of the study are expected to be able to suggest directions for capacity building and operation of health teachers.

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Deformation History of Precambrian Metamorphic Rocks in the Yeongyang-Uljin Area, Korea (영양-울진 지역 선캠브리아기 변성암류의 변형작용사)

  • Kang Ji-Hoon;Kim Nam Hoon;Park Kye-Hun;Song Yong Sun;Ock Soo-Seok
    • The Journal of the Petrological Society of Korea
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    • v.13 no.4
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    • pp.179-190
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    • 2004
  • Precambrian metamorphic rocks of Yeongyang-Uljin area, which is located in the eastern part of Sobaegsan Massif, Korea, are composed of Pyeonghae, Giseong, Wonnam Formations and Hada leuco granite gneisses. These show a zonal distribution of WNW-ESE trend, and are intruded by Mesozoic igneous rocks and are unconformably overlain by Mesozoic sedimentary rocks. This study clarifies the deformation history of Precambrian metamorphic rocks after the formation of gneissosity or schistosity on the basis of the geometric and kinematic features and the forming sequence of multi-deformed rock structures, and suggests that the geological structures of this area experienced at least four phases of deformation i.e. ductile shear deformation, one deformation before that, at least two deformations after that. (1) The first phase of deformation formed regional foliations and WNW-trending isoclinal folds with subhorizontal axes and steep axial planes dipping to the north. (2) The second phase of deformation occurred by dextral ductile shear deformation of top-to-the east movement, forming stretching lineations of E-W trend, S-C mylonitic structure foliations, and Z-shaped asymmetric folds. (3) The third phase deformation formed I-W trending open- or kink-type recumbent folds with subhorizontal axes and gently dipping axial planes. (4) The fourth phase deformation took place under compression of NNW-SSE direction, forming ENE-WSW trending symmetric open upright folds and asymmetric conjugate kink folds with subhorizontal axes, and conjugate faults thrusting to the both NNW and SSE with drag folds related to it. These four phases of deformation are closely connected with the orientation of regional foliation in the Yeongyang-Uljin area. 1st deformation produced regional foliation striking WNW and steeply dipping to the north, 2nd deformation locally change the strike of regional foliation into N-S direction, and 3rd and 4th deformations locally change dip-angle and dip-direction of regional foliation.