• 한국재료학회지
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• 제22권4호
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• pp.202-206
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• 2012

$CoSi_2$ was formed through annealing of atomic layer deposition Co thin films. Co ALD was carried out using bis(N,N'-diisopropylacetamidinato) cobalt ($Co(iPr-AMD)_2$) as a precursor and $NH_3$ as a reactant; this reaction produced a highly conformal Co film with low resistivity ($50\;{\mu}{\Omega}cm$). To prevent oxygen contamination, $ex-situ$ sputtered Ti and $in-situ$ ALD Ru were used as capping layers, and the silicide formation prepared by rapid thermal annealing (RTA) was used for comparison. Ru ALD was carried out with (Dimethylcyclopendienyl)(Ethylcyclopentadienyl) Ruthenium ((DMPD)(EtCp)Ru) and $O_2$ as a precursor and reactant, respectively; the resulting material has good conformality of as much as 90% in structure of high aspect ratio. X-ray diffraction showed that $CoSi_2$ was in a poly-crystalline state and formed at over $800^{\circ}C$ of annealing temperature for both cases. To investigate the as-deposited and annealed sample with each capping layer, high resolution scanning transmission electron microscopy (STEM) was employed with electron energy loss spectroscopy (EELS). After annealing, in the case of the Ti capping layer, $CoSi_2$ about 40 nm thick was formed while the $SiO_x$ interlayer, which is the native oxide, became thinner due to oxygen scavenging property of Ti. Although Si diffusion toward the outside occurred in the Ru capping layer case, and the Ru layer was not as good as the sputtered Ti layer, in terms of the lack of scavenging oxygen, the Ru layer prepared by the ALD process, with high conformality, acted as a capping layer, resulting in the prevention of oxidation and the formation of $CoSi_2$.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2003년도 ICCAS
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• pp.1178-1183
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• 2003

As personal robots coexist with a person with a role to help a person, while adapting various human life and environment, the personal robots have to accommodate frequently-changing or different-from-home-to-home environment. In addition, personal robots may have many kinds of different Kinematic configurations depending on the capabilities. Some may have a mobile base and others may have arms and a head. The motivation of this study arises from this not-well-defined home environment and varying Kinematic configuration. So the goal of this study is to develop a general control architecture for personal robots. There exist three major architectures; deliberative, reactive and hybrid. We found that these are applicable only for the defined environment with a fixed Kinematic configuration. Neither could accommodate the above two requirements. For the general solution, we propose a Supervised Hybrid Architecture (SHA), in which we use double layers of deliberative and reactive controls, distributed control with a modular design of Kinematic configurations, and real-time Linux OS. Deliberative and reactive actions interact through a corresponding arbitrator. These arbitrators help a robot to choose an appropriate architecture depending on the current situation to successfully perform a given task. The distributed control modules communicate through IEEE 1394 for the easy expandability. With a personal robot platform with a mobile base, two arms, a head and a pan-tilt stereo eye system, we tested the developed SHA for static as well as dynamic environments. For this application, we developed decision-making rules for selecting appropriate control methods for several situations of navigation task. Examples are shown to show the effectiveness.

• 한국동물위생학회지
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• 제43권3호
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• pp.155-159
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• 2020

This study was conducted to investigate the infection of livestock diseases using 500 blood samples from wild boars captured in six cities and one county in northern Gyeonggi province, South Korea. We examined 239 cases of classical swine fever virus (CSFV), and each of 500 cases of foot and mouth disease virus (FMDV), porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), Mycoplasma hyopneumoniae (MH), Actinobacillus pleuropneumoniae (APP), Pasteurella multocida type A (PMA), Hemophilus parasuis (HP), Salmonella (Sal.) spp. infections. Antibodies were detected against CSFV (23.4%), PRRSV (4.0%), PCV2 (60.4%), MH (3.0%), APP (69.2%), PMA (52.8%), HP (11.8%), and Sal. spp. infections (37.2%). No antibodies were detected against FMDV. As a result of antigenic analysis of 68 positive cases (13.6%) out of 500 PRRS antigen tests, 61 North American cases, 6 European cases, 1 North American-European complex case. PCV2 has 158 positive cases (31.6%) out of 500 antigen tests, and the results indicate that a considerable number of individuals are infected. To our knowledge, this is the first seroprevalence report of MH, APP, PMA, HP, and Sal. spp. infections in wild boars in South Korea.

• 정보교육학회논문지
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• 제7권1호
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• pp.80-90
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• 2003

본 연구에서는 웹기반 프로젝트 학습 활동을 지원하는 실시간 화상학습시스템을 설계 구현하고 현장에 적용하였다. 또한 실시간 화상학습시스템 활용 수업의 효과를 검증하기 위하여 교실환경검사도구인 WIHIC를 투입하여 학생들의 교실 환경에 대한 인식에 어떠한 변화가 있는가를 조사하고 그 결과를 분석하였다. 웹기반 프로젝트 학습 활동을 통한 실시간 화상학습시스템의 활용은 교실 환경 8개 영역(학생들의 단결, 교사의 지원, 수업에의 참여, 자율성, 탐구 활동, 과제지향, 협동성, 평등) 에서 학생들의 인식 변화에 긍정적인 효과가 있는 것으로 나타났으며, 본 시스템을 통하여 학생들의 자기주도적 학습력 및 ICT 활용 능력 함양, 소집단 협동 학습에서의 토론 활동의 활성화에 도움을 줄 수 있을 것으로 기대된다.

• 대한화학회지
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• 제55권5호
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• pp.846-856
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• 2011

이 연구에서는 중학교 1학년 과학영재들의 비유 만들기의 각 단계에서 나타나는 심상적 사고의 특성을 심상적 정보처리 과정의 측면에서 분석하였다. 연구 결과, 과학영재들의 비유 만들기 과정에서 이미지 산출, 이미지 조작, 이미지 표현의 심상적 정보처리 과정이 나타났다. 또한, 과학영재들은 비유 만들기 과정에서 지각 심상, 기억 심상, 상상 심상의 세 가지 유형의 심상을 활용하는 것으로 나타났으며, 활용한 심상의 유형에 따라 심상적 정보처리 과정에 차이가 있었다. 이를 바탕으로 비유 만들기에서 활용한 심상의 유형에 따른 심상적 정보처리 모델을 제안하였다. 이 연구의 결과는 비유적 사고와 심상적 사고의 상호 작용을 강조함으로써 과학영재의 심상적 사고를 촉진할 수 있는 비유 만들기 전략의 효과적인 활용 방안을 마련하는데 유용한 시사점을 제공할 수 있을 것이다.

• Archives of Plastic Surgery
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• 제44권3호
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• pp.194-201
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• 2017

Background Platelet-rich plasma (PRP) contains high concentrations of growth factors involved in wound healing. Hydrogel is a 3-dimensional, hydrophilic, high-molecular, reticular substance generally used as a dressing formulation to accelerate wound healing, and also used as a bio-applicable scaffold or vehicle. This study aimed to investigate the effects of PRP and hydrogel on wound healing, in combination and separately, in an animal wound model. Methods A total of 64 wounds, with 2 wounds on the back of each nude mouse, were classified into 4 groups: a control group, a hydrogel-only group, a PRP-only group, and a combined-treatment group. All mice were assessed for changes in wound size and photographed on scheduled dates. The number of blood vessels was measured in all specimens. Immunohistochemical staining was used for the analysis of vascular endothelial growth factor (VEGF) expression. Results Differences in the decrease and change in wound size in the combined-treatment group were more significant than those in the single-treatment groups on days 3, 5, 7, and 10. Analysis of the number of blood vessels through histological examination showed a pattern of increase over time that occurred in all groups, but the combined-treatment group exhibited the greatest increase on days 7 and 14. Immunohistochemical staining showed that VEGF expression in the combined-treatment group exhibited its highest value on day 7. Conclusions This experiment demonstrated improved wound healing using a PRP-hydrogel combined treatment compared to either treatment individually, resulting in a decrease in wound size and a shortening of the healing period.

• 한국철도학회논문집
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• 제20권1호
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• pp.31-42
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• 2017

철도 시스템의 전력 소비를 줄이기 위한 많은 연구가 진행되고 있다. 그 중에서 급속충전방식 무가선 전동차 시스템은 철도 분야에서 매우 효율적인 에너지 절감 기술로 주목 받고 있다. 본 논문에서는 ESS를 이용한 급속충전 무가선 전동차 시스템을 소개하고 현재의 도시철도 전기요금 산정방식에 대하여 분석하였다. 이러한 분석을 바탕으로 급속 충전 무가선 전동차 시스템 적용 가능한 두 가지 전기요금 저감 방안(기본요금을 저감하는 방식(Case 1)과 전력량요금을 저감시키는 방식(Case 2))을 제안하였다. 제한하는 방식의 타당성 확인을 위해 현재 운영 중인 전동차 시스템(도시철도 2호선)의 전기요금과 비교하여 비용 경제성을 평가하였다.

• 한국위성정보통신학회논문지
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• 제9권3호
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• pp.109-115
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• 2014

본 논문에서는 위성영상처리 소프트웨어 및 시스템의 재사용성을 높이고, 개발기간 및 유지 관리 비용을 줄일 수 있는 알고리즘 컴포넌트화를 통한 위성영상처리 프레임워크 및 시스템에 대한 구조를 제안한다. 기존 위성영상처리 소프트웨어 및 시스템은 특정 데이터 및 기능에 국한되어 제한된 구조를 갖고 있다. 또한, 각각의 시스템들은 동일 및 유사한 영상처리 알고리즘이 사용되지만 해당 알고리즘을 중복적으로 개발하는 문제점이 있다. 이와 같은 문제점을 해결하기 위해 위성영상처리 소프트웨어 프레임워크의 요구사항을 분석하였다. 요구사항을 반영한 프레임워크 및 시스템 구조를 설계하였으며, 위성영상처리 프레임워크의 운영흐름도 함께 도출하였다.

• 한국발생생물학회지:발생과생식
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• 제20권3호
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• pp.255-266
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• 2016

The optimum concentrations of clove oil as an anesthetic for olive flounder (Paralichthys olivaceus) and the stress response of the fish to clove oil anesthesia were determined over a range of water temperatures, and investigated in a simulated transport experiment using analysis of various water and physiological parameters. While the time for induction of anesthesia decreased significantly as both the concentration of clove oil and water temperature increased, the recovery time increased significantly (P<0.05). The plasma cortisol concentration in fish at each temperature increased significantly up to 12 h following exposure (P<0.05), then decreased to 48 h (P<0.05). The DO dissolved oxygen concentrations, pH values, and the fish respiratory frequencies decreased over 6 h following exposure to clove oil in all experimental groups (P<0.05), whereas the $NH_4{^+}$ and $CO_2$ concentrations in all experimental groups increased up to 6 h (P<0.05). The pH values and DO concentrations increased with increasing clove oil concentration (P<0.05) in the 6 h following exposure, and the $CO_2$ and $NH_4{^+}$ concentrations and the respiratory frequencies decreased with increasing clove oil concentration (P<0.05). The results of this experiment suggest that clove oil reduced the metabolic activity of olive flounder, thus reducing $NH_4{^+}$ excretion and $O_2$ consumption. In conclusion, clove oil appears to be a cost-effective and efficient anesthetic that is safe for use and non-toxic to the fish and users. Its use provides the potential for improved transportation of olive flounder.

• Journal of Microbiology and Biotechnology
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• 제27권4호
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• pp.694-700
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• 2017

Clostridium difficile, which causes pseudomembranous colitis, releases toxin A and toxin B. These toxins are considered to be the main causative agents for the disease pathogenesis, and their expression is associated with a marked increase of apoptosis in mucosal epithelial cells. Colonic epithelial cells are believed to form a physical barrier between the lumen and the submucosa, and abnormally increased mucosal epithelial cell apoptosis is considered to be an initial step in gut inflammation responses. Therefore, one approach to treating pseudomembranous colitis would be to develop agents that block the mucosal epithelial cell apoptosis caused by toxin A, thus restoring barrier function and curing inflammatory responses in the gut. We recently isolated an antimicrobial peptide, Periplanetasin-2 (Peri-2, YPCKLNLKLGKVPFH) from the American cockroach, whose extracts have shown great potential for clinical use. Here, we assessed whether Peri-2 could inhibit the cell toxicity and inflammation caused by C. difficile toxin A. Indeed, in human colonocyte HT29 cells, Peri-2 inhibited the toxin A-induced decrease in cell proliferation and ameliorated the cell apoptosis induced by this toxin. Moreover, in the toxin A-induced mouse enteritis model, Peri-2 blocked the mucosal disruption and inflammatory response caused by toxin A. These results suggest that the American cockroach peptide Peri-2 could be a possible drug candidate for addressing the pseudomembranous colitis caused by C. difficile toxin A.